Home Other Building Blocks 943540-74-7
943540-74-7,MFCD31657377
Catalog No.:AA01EO61

943540-74-7 | JNJ-38877618

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$123.00   $86.00
- +
2mg
95%
1 week  
$151.00   $106.00
- +
5mg
95%
1 week  
$216.00   $152.00
- +
10mg
95%
1 week  
$311.00   $218.00
- +
25mg
95%
1 week  
$568.00   $398.00
- +
50mg
95%
1 week  
$811.00   $568.00
- +
100mg
95%
1 week  
$1,131.00   $792.00
- +
500mg
95%
1 week  
$2,206.00   $1,544.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EO61
Chemical Name:
JNJ-38877618
CAS Number:
943540-74-7
Molecular Formula:
C20H12F2N6
Molecular Weight:
374.3463
MDL Number:
MFCD31657377
SMILES:
FC(c1nnc2n1nc(cc2)c1ccncc1)(c1ccc2c(c1)cccn2)F
Properties
Computed Properties
 
Complexity:
543  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
7  
Rotatable Bond Count:
3  
XLogP3:
2.7  

Downstream Synthesis Route
Literature

Title: Libouban M, et al. OMO-1, a potent, highly selective, orally bioavailable, Met kinase inhibitor with a favorable preclinical toxicity profile, shows both monotherapy activity, against Met pathway-driven tumors, and EGFR TKI combination activity in acquired resistance models [abstract In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 4791.

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SDS
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Tags:943540-74-7 Molecular Formula|943540-74-7 MDL|943540-74-7 SMILES|943540-74-7 JNJ-38877618