Catalog No.:AA00II2D

944118-01-8 | Peficitinib

Name: Name:Peficitinib
Brand: AABLOCKS
SKU: AA00II2D
Availability: InStock
Rating: 90 (10 reviews)

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Purity

Availability

Price(USD)

Quantity

1mg

≥98%

in stock

$63.00 $44.00

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5mg

≥98%

in stock

$230.00 $161.00

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10mg

≥98%

in stock

$336.00 $235.00

- +

Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA00II2D

Chemical Name:

Peficitinib

CAS Number:

944118-01-8

Molecular Formula:

C18H22N4O2

Molecular Weight:

326.3929

MDL Number:

MFCD28502035

SMILES:

NC(=O)c1cnc2c(c1NC1C3CC4CC1CC(C3)(C4)O)cc[nH]2

Properties

Computed Properties

Complexity:

525

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

1.9

Literature

Title: A novel JAK inhibitor, peficitinib, demonstrates potent efficacy in a rat adjuvant-induced arthritis model.

Journal: Journal of pharmacological sciences 20170101

Title: A phase 2a randomized, double-blind, placebo-controlled, sequential dose-escalation study to evaluate the efficacy and safety of ASP015K, a novel Janus kinase inhibitor, in patients with moderate-to-severe psoriasis.

Journal: The British journal of dermatology 20150901

Title: In vitro/in vivo investigations to examine the gender differences in the pharmacokinetics of novel oral Janus kinase (JAK) inhibitor ASP015K and sulfate metabolite M2 in rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20150101

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SDS