Title: Blocking Scn10a channels in heart reduces late sodium current and is antiarrhythmic.
Journal: Circulation research 20120720
Title: A channelopathy contributes to cerebellar dysfunction in a model of multiple sclerosis.
Journal: Annals of neurology 20120201
Title: The differential effect of intrathecal Nav1.8 blockers on the induction and maintenance of capsaicin- and peripheral ischemia-induced mechanical allodynia and thermal hyperalgesia.
Journal: Anesthesia and analgesia 20120101
Title: Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis.
Journal: Arthritis research & therapy 20120101
Title: Na(v)1.8 channelopathy in mutant mice deficient for myelin protein zero is detrimental to motor axons.
Journal: Brain : a journal of neurology 20110201
Title: Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives.
Journal: Bioorganic & medicinal chemistry letters 20101115
Title: Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS.
Journal: Journal of neurochemistry 20100601
Title: Structural determinants of drugs acting on the Nav1.8 channel.
Journal: The Journal of biological chemistry 20090417
Title: Additive antinociceptive effects of the selective Nav1.8 blocker A-803467 and selective TRPV1 antagonists in rat inflammatory and neuropathic pain models.
Journal: The journal of pain : official journal of the American Pain Society 20090301
Title: A selective Nav1.8 sodium channel blocker, A-803467 [5-(4-chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide], attenuates spinal neuronal activity in neuropathic rats.
Journal: The Journal of pharmacology and experimental therapeutics 20080301
Title: Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain.
Journal: Journal of medicinal chemistry 20080214
Title: Painful research: identification of a small-molecule inhibitor that selectively targets Nav1.8 sodium channels.
Journal: Molecular interventions 20070801
Title: Sodium channel blockers.
Journal: Journal of medicinal chemistry 20070531
Title: A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20070515
Title: Block of Nav1.8 by small molecules.
Journal: Channels (Austin, Tex.) 20070101
Title: Anreddy N, et al. A-803467, a tetrodotoxin-resistant sodium channel blocker, modulates ABCG2-mediated MDR in vitro and in vivo. Oncotarget. 2015;6(36):39276-39291.
Title: Jarvis MF, et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci U S A. 2007;104(20):8520-8525.