Home Amines 945-24-4
945-24-4,MFCD00006711
Catalog No.:AA0032X3

945-24-4 | 2,4-Diamino-6-(hydroxymethyl)pteridine

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Purity
Availability
Price(USD)
Quantity
  
1g
95%
in stock  
$21.00   $15.00
- +
5g
95%
in stock  
$56.00   $39.00
- +
25g
95%
in stock  
$155.00   $109.00
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100g
95%
in stock  
$401.00   $281.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0032X3
Chemical Name:
2,4-Diamino-6-(hydroxymethyl)pteridine
CAS Number:
945-24-4
Molecular Formula:
C7H8N6O
Molecular Weight:
192.1780
MDL Number:
MFCD00006711
SMILES:
OCc1cnc2c(n1)c(N)nc(n2)N
Properties
Properties
 
BP:
560.2°C at 760 mmHg  
Form:
Solid  
MP:
>236ºC (dec.)  
Storage:
Light sensitive;Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
203  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
-1.7  

Literature

Title: Resistance of a rodent malaria parasite to a thymidylate synthase inhibitor induces an apoptotic parasite death and imposes a huge cost of fitness.

Journal: PloS one 20110101

Title: Plasmodium berghei: lack of antimalarial activity of an analogue of folate precursor, 2,4-diamino-6-hydroxymethylpteridine in a mouse model.

Journal: Experimental parasitology 20081101

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Determination of the chiral and achiral related substances of methotrexate by cyclodextrin-modified micellar electrokinetic chromatography.

Journal: Electrophoresis 20040801

Title: Photohydrolysis of methotrexate produces pteridine, which induces poly-G-specific DNA damage through photoinduced electron transfer.

Journal: Photochemistry and photobiology 20021101

Title: Design, synthesis, computational prediction, and biological evaluation of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii.

Journal: Journal of medicinal chemistry 20010719

Title: Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds.

Journal: Journal of medicinal chemistry 19990826

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SDS
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