Name: Name:N-benzyl-4-chloro-N-cyclohexylbenzamide
Brand: AABLOCKS
SKU: AA01A0HR
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA01A0HR

Chemical Name: N-benzyl-4-chloro-N-cyclohexylbenzamide

CAS Number: 945714-67-0

Molecular Formula: C20H22ClNO

Molecular Weight: 327.8478

MDL Number: MFCD22378757

SMILES: Clc1ccc(cc1)C(=O)N(C1CCCCC1)Cc1ccccc1

Properties

Complexity: 366

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 23

Hydrogen Bond Acceptor Count: 1

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 4

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 5.3

Literature fold

Title: A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease.

Journal: The Journal of clinical investigation20120402

Title: Deane R, et al. A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease. J Clin Invest. 2012 Apr;122(4):1377-92.

Title: Hong Y, et al. Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus. Neurochem Res. 2016 May;41(5):1192-9.

Title: Lian YJ, et al. Ds-HMGB1 and fr-HMGB induce depressive behavior through neuroinflammation in contrast to nonoxid-HMGB1. Brain Behav Immun. 2017 Jan;59:322-332.

945714-67-0 | N-benzyl-4-chloro-N-cyclohexylbenzamide