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Home Amines 945755-56-6
945755-56-6,MFCD24386874
Catalog No.:AA01DMV8

945755-56-6 | Pyrrolidine-2-carboxylic acid {4-[2-(4-morpholin-4-yl-phenylamino)-pyrimidin-4-yl]-phenyl}-amide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$19.00   $14.00
- +
2mg
98+%
in stock  
$27.00   $19.00
- +
5mg
98+%
in stock  
$37.00   $26.00
- +
10mg
98+%
in stock  
$52.00   $36.00
- +
25mg
98+%
in stock  
$87.00   $61.00
- +
  • Technical Information
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  • Technical Information
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Technical Information
Catalog Number:
AA01DMV8
Chemical Name:
Pyrrolidine-2-carboxylic acid {4-[2-(4-morpholin-4-yl-phenylamino)-pyrimidin-4-yl]-phenyl}-amide
CAS Number:
945755-56-6
Molecular Formula:
C25H28N6O2
Molecular Weight:
444.5288
MDL Number:
MFCD24386874
SMILES:
O=C([C@@H]1CCCN1)Nc1ccc(cc1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1
Properties
Computed Properties
 
Complexity:
614  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
6  
XLogP3:
2.8  

Literature

Title: SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20121215

Title: Forsyth T, et al. SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7653-8.

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Tags:945755-56-6 Molecular Formula|945755-56-6 MDL|945755-56-6 SMILES|945755-56-6 Pyrrolidine-2-carboxylic acid {4-[2-(4-morpholin-4-yl-phenylamino)-pyrimidin-4-yl]-phenyl}-amide