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Home Other Building Blocks 946075-13-4
946075-13-4,MFCD27987905
Catalog No.:AA01EMWU

946075-13-4 | Isavuconazonium sulfate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$165.00   $115.00
- +
25mg
97%
in stock  
$247.00   $173.00
- +
100mg
97%
in stock  
$922.00   $645.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EMWU
Chemical Name:
Isavuconazonium sulfate
CAS Number:
946075-13-4
Molecular Formula:
C35H36F2N8O9S2
Molecular Weight:
814.8353
MDL Number:
MFCD27987905
SMILES:
[O-]S(=O)(=O)O.CNCC(=O)OCc1cccnc1N(C(=O)OC([n+]1cnn(c1)C[C@](c1cc(F)ccc1F)([C@H](c1scc(n1)c1ccc(cc1)C#N)C)O)C)C
Properties

Downstream Synthesis Route
CASUnavailable 
  946075-13-4 

[1]CurrentPatentAssignee:WOCKHARDTLIMITED-WO2016/16766,2016,A2Locationinpatent:Page/Pagecolumn15

[1]CurrentPatentAssignee:SINOBIOPHARMACEUTICALLIMITED-CN106565699,2017,ALocationinpatent:Paragraph0037-0047

241479-67-4   
1-N-methyl-N-3-(methylamino)acetoxymethylpyridin-2-ylcarbamoyloxyethyl-1-(2R,3R)-2-(2,5-difluorophenyl)-2-hydroxy-3-4-(4-cyanophenyl)thiazol-2-ylbutyl-1H-1,2,4-triazo-4-iumsulfate 

[1]Patent:CN110128420,2019,A

[2]Patent:CN110128420,2019,A

[1]CurrentPatentAssignee:YinQiming;LiJia;MaoJun;ZhouWeihai-CN110128420,2019,A

[2]CurrentPatentAssignee:YinQiming;LiJia;MaoJun;ZhouWeihai-CN110128420,2019,A

[3]CurrentPatentAssignee:SHANGHAIDESANOCHEMICALPHARMACEUTICALCO.;SHANGHAIDESANOBIO-PHARMACEUTICALCO.;SHANGHAIDESANOPHARMACEUTICALSCO.-US2023/75632,2023,A1

[1]CurrentPatentAssignee:YinQiming;LiJia;MaoJun;ZhouWeihai-CN110128420,2019,A

[2]CurrentPatentAssignee:YANGTZERIVERPHARMACEUTICALGROUPCOLTD-CN115215857,2022,ALocationinpatent:Paragraph0078-0100

[3]CurrentPatentAssignee:SHANGHAIDESANOCHEMICALPHARMACEUTICALCO.;SHANGHAIDESANOBIO-PHARMACEUTICALCO.;SHANGHAIDESANOPHARMACEUTICALSCO.-US2023/75632,2023,A1

Literature

Title: Schmitt-Hoffmann AH, et al. Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01292-17.

Title: Murrell D, et al. Isavuconazonium sulfate: a triazole prodrug for invasive fungal infections. Int J Pharm Pract. 2017 Feb;25(1):18-30.

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SDS
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