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Home Amines 952753-59-2
952753-59-2,MFCD24642255
Catalog No.:AA00IKKL

952753-59-2 | 2-amino-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile

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100mg
98%
in stock  
$7.00   $5.00
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250mg
98%
in stock  
$16.00   $11.00
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1g
98%
in stock  
$48.00   $34.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
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Technical Information
Catalog Number:
AA00IKKL
Chemical Name:
2-amino-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile
CAS Number:
952753-59-2
Molecular Formula:
C10H6FN3S
Molecular Weight:
219.2381
MDL Number:
MFCD24642255
SMILES:
N#Cc1sc(nc1c1ccc(cc1)F)N
Properties

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,2017,vol.60,p.3580-3590

[2]Patent:WO2014/139882,2014,A1.Locationinpatent:Paragraph00436-00437

[3]Patent:WO2014/202458,2014,A1.Locationinpatent:Paragraph00388

952753-59-2   
2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)-3,3-dimethylpiperazin-1-yl)-8-methylimidazo1,2-apyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile 

[1]CurrentPatentAssignee:GALAPAGOS-WO2014/139882,2014,A1

952753-59-2   
2-(6-bromo-2-ethyl-8-methyl-imidazo1,2-apyridin-3-yl)-methyl-amino-4-(4-fluoro-phenyl)-thiazole-5-carbonitrile 

[1]CurrentPatentAssignee:GALAPAGOS-WO2014/139882,2014,A1

[2]Desroy,Nicolas;Housseman,Christopher;Bock,Xavier;Joncour,Agnès;Bienvenu,Natacha;Cherel,Laëtitia;Labeguere,Virginie;Rondet,Emilie;Peixoto,Christophe;Grassot,Jean-Marie;Picolet,Olivier;Annoot,Denis;Triballeau,Nicolas;Monjardet,Alain;Wakselman,Emanuelle;Roncoroni,Veronique;LeTallec,Sandrine;Blanque,Roland;Cottereaux,Celine;Vandervoort,Nele;Christophe,Thierry;Mollat,Patrick;Lamers,Marieke;Auberval,Marielle;Hrvacic,Boska;Ralic,Jovica;Oste,Line;VanderAar,Ellen;Brys,Reginald;Heckmann,Bertrand[JournalofMedicinalChemistry,2017,vol.60,#9,p.3580-3590]

952753-59-2   
2-chloro-4-(4-fluoro-phenyl)-thiazole-5-carbonitrile 

[1]Chen,Jiahui;Deng,Xiaoyun;Haider,Ahmed;Josephson,Lee;Liang,StevenH.;Perrakis,Anastassis;Rong,Jian;Salgado-Polo,Fernando;Shao,Tuo;Shao,Yihan;Van,Richard;Xiao,Zhiwei[JournalofMedicinalChemistry,2021,vol.64,#20,p.15053-15068]

[2]Desroy,Nicolas;Housseman,Christopher;Bock,Xavier;Joncour,Agnès;Bienvenu,Natacha;Cherel,Laëtitia;Labeguere,Virginie;Rondet,Emilie;Peixoto,Christophe;Grassot,Jean-Marie;Picolet,Olivier;Annoot,Denis;Triballeau,Nicolas;Monjardet,Alain;Wakselman,Emanuelle;Roncoroni,Veronique;LeTallec,Sandrine;Blanque,Roland;Cottereaux,Celine;Vandervoort,Nele;Christophe,Thierry;Mollat,Patrick;Lamers,Marieke;Auberval,Marielle;Hrvacic,Boska;Ralic,Jovica;Oste,Line;VanderAar,Ellen;Brys,Reginald;Heckmann,Bertrand[JournalofMedicinalChemistry,2017,vol.60,#9,p.3580-3590]

[3]CurrentPatentAssignee:SUZHOUSINOVENTPHARMACEUTICALS-US2020/369676,2020,A1Locationinpatent:Paragraph0809;0812

[4]CurrentPatentAssignee:GALAPAGOS-WO2014/139882,2014,A1Locationinpatent:Paragraph00438-00439

[5]CurrentPatentAssignee:GALAPAGOS-WO2014/202458,2014,A1Locationinpatent:Paragraph00390;00391

952753-59-2   
2-6-(3,3-dimethyl-piperazin-1-yl)-2-ethyl-8-methyl-imidazo1,2-apyridin-3-yl-methyl-amino}-4-(4-fluoro-phenyl)-thiazole-5-carbonitrile 

[1]CurrentPatentAssignee:GALAPAGOS-WO2014/139882,2014,A1

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