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954126-98-8,MFCD27987922
Catalog No.:AA01DGGC

954126-98-8 | DANIRIXIN

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$26.00   $19.00
- +
5mg
98+%
in stock  
$66.00   $46.00
- +
10mg
98+%
in stock  
$98.00   $68.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01DGGC
Chemical Name:
DANIRIXIN
CAS Number:
954126-98-8
Molecular Formula:
C19H21ClFN3O4S
Molecular Weight:
441.9041
MDL Number:
MFCD27987922
SMILES:
O=C(Nc1cccc(c1C)F)Nc1ccc(c(c1O)S(=O)(=O)[C@H]1CCCNC1)Cl
Properties
Computed Properties
 
Complexity:
677  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.1  

Downstream Synthesis Route

[1]Patent:US2007/249672,2007,A1.Locationinpatent:Page/Pagecolumn11

954126-98-8   
N-{4-chloro-2-hydroxy-3-(3S)-3-piperidinylsulfonylphenyl}-N'-(3-fluoro-2-methylphenyl)ureahydrobromide 

[1]Patent:WO2015/71235,2015,A1.Locationinpatent:Page/Pagecolumn16

Literature

Title: The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756)--a selective CXCR2 antagonist --in healthy adult subjects.

Journal: BMC pharmacology & toxicology 20150101

Title: Miller BE, et al. The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756)--a selective CXCR2 antagonist?--in healthy adult subjects. BMC Pharmacol Toxicol. 2015 Jun 20;16:18.

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SDS
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200274-73-3

200274-73-3

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700816-98-4

 2034493-02-0

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Tags:954126-98-8 Molecular Formula|954126-98-8 MDL|954126-98-8 SMILES|954126-98-8 DANIRIXIN
Catalog No.: AA01DGGC
954126-98-8,MFCD27987922
954126-98-8 | DANIRIXIN
Pack Size： 1mg
Purity： 98+%
in stock
$26.00 $19.00
Pack Size： 5mg
Purity： 98+%
in stock
$66.00 $46.00
Pack Size： 10mg
Purity： 98+%
in stock
$98.00 $68.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA01DGGC
Chemical Name: DANIRIXIN
CAS Number: 954126-98-8
Molecular Formula: C19H21ClFN3O4S
Molecular Weight: 441.9041
MDL Number: MFCD27987922
SMILES: O=C(Nc1cccc(c1C)F)Nc1ccc(c(c1O)S(=O)(=O)[C@H]1CCCNC1)Cl
Properties
Complexity: 677  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 29  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 4  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.1  
Downstream Synthesis Route
954127-43-6    954126-98-8 

[1]Patent:US2007/249672,2007,A1.Locationinpatent:Page/Pagecolumn11

954126-98-8   
N-{4-chloro-2-hydroxy-3-(3S)-3-piperidinylsulfonylphenyl}-N'-(3-fluoro-2-methylphenyl)ureahydrobromide 

[1]Patent:WO2015/71235,2015,A1.Locationinpatent:Page/Pagecolumn16

Literature fold

Title: The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756)--a selective CXCR2 antagonist --in healthy adult subjects.

Journal: BMC pharmacology & toxicology20150101

Title: Miller BE, et al. The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756)--a selective CXCR2 antagonist?--in healthy adult subjects. BMC Pharmacol Toxicol. 2015 Jun 20;16:18.

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700816-98-4
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2034493-02-0
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