Home Other Building Blocks 956590-23-1
956590-23-1,MFCD22380608
Catalog No.:AA01DX24

956590-23-1 | UNBS5162

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$39.00   $28.00
- +
5mg
≥98%
in stock  
$116.00   $81.00
- +
10mg
98%
in stock  
$146.00   $103.00
- +
25mg
98%
in stock  
$247.00   $173.00
- +
50mg
98%
in stock  
$320.00   $224.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01DX24
Chemical Name:
UNBS5162
CAS Number:
956590-23-1
Molecular Formula:
C17H18N4O3
Molecular Weight:
326.3498
MDL Number:
MFCD22380608
SMILES:
CN(CCn1c(=O)c2cc(NC(=O)N)cc3c2c(c1=O)ccc3)C
Properties
Computed Properties
 
Complexity:
536  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
0.8  

Downstream Synthesis Route

[1]CurrentPatentAssignee:UNIBIOSCREEN-WO2007/128538,2007,A1Locationinpatent:Page/Pagecolumn21

[1]CurrentPatentAssignee:UNIBIOSCREEN-WO2007/128538,2007,A1Locationinpatent:Page/Pagecolumn25

Literature

Title: UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.

Journal: Neoplasia (New York, N.Y.) 20080601

Title: Mijatovic T, et al. UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers. Neoplasia. 2008 Jun;10(6):573-86.

Title: Tina Mahieu, et al. UNBS5162: A novel naphthalimide derivative with potent pro-autophagic effects in human cancer cells. Cancer Research, 2007 May; 67(9) Supplement.

Title: He D, et al. UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway. Mol Med Rep. 2018 Jan;17(1):549-555.

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SDS
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