Home Deuterated Building Blocks 97-56-3
97-56-3,MFCD00007733
Catalog No.:AA00IJTE

97-56-3 | 2-Methyl-5-(p-tolyldiazenyl)aniline

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100g
≥ 99% (Assay)
in stock  
$65.00   $46.00
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250g
≥ 99% (Assay)
in stock  
$102.00   $72.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IJTE
Chemical Name:
2-Methyl-5-(p-tolyldiazenyl)aniline
CAS Number:
97-56-3
Molecular Formula:
C14H15N3
Molecular Weight:
225.2890
MDL Number:
MFCD00007733
SMILES:
Cc1ccc(cc1)/N=N/c1ccc(c(c1)N)C
Properties
Computed Properties
 
Complexity:
264  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
3.7  

Literature

Title: OAT and 3'MeDAB azo compounds similarly cause liver tumors in GR mice, but differently modify activities of FoxA transcription factors.

Journal: Bulletin of experimental biology and medicine 20111101

Title: Ortho-aminoazotoluene activates mouse constitutive androstane receptor (mCAR) and increases expression of mCAR target genes.

Journal: Toxicology and applied pharmacology 20110815

Title: [Metabolism inhibition stimulates, metabolism activation inhibits cancerogenic activity of ortho-aminoazotoluene in mouse liver].

Journal: Voprosy onkologii 20110101

Title: o-Aminoazotoluene.

Journal: Report on carcinogens : carcinogen profiles 20110101

Title: [O-aminoazotoluene inhibits DENA-induced hepatocarcinogenesis when used together in mice].

Journal: Voprosy onkologii 20100101

Title: Biological Basis of Differential Susceptibility to Hepatocarcinogenesis among Mouse Strains.

Journal: Journal of toxicologic pathology 20090301

Title: O-aminoazotoluene suppresses hepatocyte proliferation in inbred mice susceptible to hepatocarcinogenesis.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20090101

Title: Orto-aminoazotoluen induces the expression of the p53 gene in inbred strains of mice susceptible and resistant to hepatocarcinogenesis.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20090101

Title: Effects of o-aminoazotoluene on liver regeneration and p53 activation in mice susceptible and resistant to hepatocarcinogenesis.

Journal: Toxicology 20081205

Title: Detection of target genes of FOXA transcription factors involved in proliferation control.

Journal: Biochemistry. Biokhimiia 20080101

Title: Promoting effect of o-aminoazotoluene on hepatocarcinogenesis is accompanied by the increase in inflammatory and proliferative processes in liver tissue and decrease in the concentration of free thyroxin in the blood.

Journal: Bulletin of experimental biology and medicine 20071201

Title: FOXA transcription factors determine the amplitude of glucocorticoid induction of tyrosine aminotransferase in mice.

Journal: Bulletin of experimental biology and medicine 20071101

Title: Activation of constitutive androstane receptor under the effect of hepatocarcinogenic aminoazo dyes in mouse and rat liver.

Journal: Bulletin of experimental biology and medicine 20070901

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Species-specific effects of the hepatocarcinogens 3'-methyl-4-dimethyl-aminoazobenzene and ortho-aminoazotoluene in mouse and rat liver.

Journal: Molecular carcinogenesis 20051201

Title: o-Aminoazotoluene does induce the enzymes of its own mutagenic activation in mouse liver.

Journal: Toxicology 20050701

Title: Flocculation behaviour of model textile wastewater treated with a food grade polysaccharide.

Journal: Journal of hazardous materials 20050214

Title: Relationship between high sensitivity of suckling mice to hepatocarcinogenic and antiglucocorticoid effects of o-aminoazotoluene and diethylnitrosamine.

Journal: Bulletin of experimental biology and medicine 20040601

Title: [Different sensitivity of inbred mice to hepatocarcinogen ortho-aminoazotoluene may be due to differences in the negative control mechanisms of hepatocyte proliferation].

Journal: Tsitologiia 20040101

Title: The unknown nuclear protein that decreases HNF3 activity ensures species specificity of action of hepatocarcinogenic amino azo dyes.

Journal: Doklady. Biochemistry and biophysics 20040101

Title: o-Aminoazotoluene.

Journal: Report on carcinogens : carcinogen profiles 20040101

Title: Cytochrome P4501A1 and 1A2 gene expression in the liver of 3-methylcholanthrene- and o-aminoazotoluene-treated mice: a comparison between PAH-responsive and PAH-nonresponsive strains.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030501

Title: Species specific hepatocarcinogen inhibition of the glucocorticoid induction of tyrosine aminotransferase gene in mouse and rat liver.

Journal: Biochemistry. Biokhimiia 20030501

Title: [mRNA level and cytochrome P450 1A activity in the liver of C57BL mice induced by various xenobiotics].

Journal: Biomeditsinskaia khimiia 20030101

Title: o-Aminoazotoluene.

Journal: Report on carcinogens : carcinogen profiles 20020101

Title: Lack of effect of furfural on unscheduled DNA synthesis in the in vivo rat and mouse hepatocyte DNA repair assays and in precision-cut human liver slices.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20011001

Title: Involvement of transcription factor HNF3gamma in the effect of o-aminoazotoluene on glucocorticoid induction of tyrosine aminotransferase in mice sensitive to its hepatocarcinogenic action.

Journal: Molecular carcinogenesis 20010501

Title: Mutation spectrum of o-aminoazotoluene in the cII gene of lambda/lacZ transgenic mice (MutaMouse).

Journal: Mutation research 20010405

Title: [Effect of the hepatocarcinogen ortho-aminoazotoluene on induction of tyrosine-aminotransferase by glucocorticoids in mouse liver].

Journal: Molekuliarnaia biologiia 20010101

Title: Expression of CYP1A in liver of A/Sn and CC57BR mice differing in sensitivity to hepatocarcinogenesis induced by o-aminoazotoluene.

Journal: Biochemistry. Biokhimiia 20000601

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