Home Fluorides 97009-67-1
97009-67-1,MFCD01314307
Catalog No.:AA006NWO

97009-67-1 | 1-(4-Fluorophenyl)cyclopropanecarbonitrile

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Purity
Availability
Price(USD)
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250mg
98%
in stock  
$6.00   $4.00
- +
1g
98%
in stock  
$8.00   $6.00
- +
5g
98%
in stock  
$38.00   $27.00
- +
10g
98%
in stock  
$68.00   $48.00
- +
25g
98%
in stock  
$140.00   $98.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA006NWO
Chemical Name:
1-(4-Fluorophenyl)cyclopropanecarbonitrile
CAS Number:
97009-67-1
Molecular Formula:
C10H8FN
Molecular Weight:
161.1756
MDL Number:
MFCD01314307
SMILES:
N#CC1(CC1)c1ccc(cc1)F
Properties
Properties
 
BP:
268.7 °C at 760 mmHg  
Form:
Liquid  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
215  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
2  

Downstream Synthesis Route

[1]Huang,Adrian;Moretto,Alessandro;Janz,Kristin;Lowe,Michael;Bedard,PatriciaW.;Tam,Steve;Di,Li;Clerin,Valerie;Sushkova,Natalia;Tchernychev,Boris;Tsao,DesireeH.H.;KeithJr.,JamesC.;Shaw,GrayD.;Schaub,RobertG.;Wang,Qin;Kaila,Neelu[JournalofMedicinalChemistry,2010,vol.53,#16,p.6003-6017]

[2]Locationinpatent:experimentalpartTu,Hua;Powers,JayP.;Liu,Jinsong;Ursu,Stefania;Sudom,Athena;Yan,Xuelei;Xu,Haoda;Meininger,David;DeGraffenreid,Michael;He,Xiao;Jaen,JuanC.;Sun,Daqing;Labelle,Marc;Yamamoto,Hiroshi;Shan,Bei;Walker,NigelP.C.;Wang,Zhulun[BioorganicandMedicinalChemistry,2008,vol.16,#19,p.8922-8931]

[3]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-WO2019/3143,2019,A1Locationinpatent:Page/Pagecolumn32;33

[4]Fedorynski,Michal;Jonczyk,Andrzej[OrganicPreparationsandProceduresInternational,1995,vol.27,#3,p.355-359]

[5]Locationinpatent:schemeortableYoon,YoungAe;Park,ChanSun;Cha,MyungHun;Choi,Hyunho;Sim,JaeYoung;Kim,JaeGyu[BioorganicandMedicinalChemistryLetters,2010,vol.20,#19,p.5735-5738]

[6]CurrentPatentAssignee:7TMPHARMAAS-WO2007/62773,2007,A1Locationinpatent:Page/Pagecolumn17;22

[7]CurrentPatentAssignee:PFIZERINC-WO2008/50200,2008,A1Locationinpatent:Page/Pagecolumn37

[8]CurrentPatentAssignee:MERCK&COINC-WO2003/104207,2003,A2Locationinpatent:Page52-53

[9]Shi,Yongjia;Gao,Qian;Xu,Senmiao[JournaloftheAmericanChemicalSociety,2019,vol.141,#27,p.10599-10604]

[1]Arava,VeeraReddy;Siripalli,UdayaBhaskaraRao;Dubey,PramodKumar[TetrahedronLetters,2005,vol.46,#42,p.7247-7248]

[1]CurrentPatentAssignee:PFIZERINC-WO2008/50200,2008,A1Locationinpatent:Page/Pagecolumn37-38

[1]Locationinpatent:experimentalpartTu,Hua;Powers,JayP.;Liu,Jinsong;Ursu,Stefania;Sudom,Athena;Yan,Xuelei;Xu,Haoda;Meininger,David;DeGraffenreid,Michael;He,Xiao;Jaen,JuanC.;Sun,Daqing;Labelle,Marc;Yamamoto,Hiroshi;Shan,Bei;Walker,NigelP.C.;Wang,Zhulun[BioorganicandMedicinalChemistry,2008,vol.16,#19,p.8922-8931]

[2]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-WO2019/3143,2019,A1Locationinpatent:Page/Pagecolumn32;33

97009-67-1   
1-(4-fluorophenyl)cyclopropane-1-carboxylicacid 

[1]Huang,Adrian;Moretto,Alessandro;Janz,Kristin;Lowe,Michael;Bedard,PatriciaW.;Tam,Steve;Di,Li;Clerin,Valerie;Sushkova,Natalia;Tchernychev,Boris;Tsao,DesireeH.H.;KeithJr.,JamesC.;Shaw,GrayD.;Schaub,RobertG.;Wang,Qin;Kaila,Neelu[JournalofMedicinalChemistry,2010,vol.53,#16,p.6003-6017]

[2]Lee,Taegyo;Hartwig,JohnF.[AngewandteChemie-InternationalEdition,2016,vol.55,#30,p.8723-8727][Angew.Chem.,2016,vol.128,#30,p.8865-8869,5]

[3]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-WO2019/3143,2019,A1

[4]Shi,Yongjia;Gao,Qian;Xu,Senmiao[JournaloftheAmericanChemicalSociety,2019,vol.141,#27,p.10599-10604]

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