Catalog No.:AA01E6EM

97534-21-9 | 6-Hydroxy-4-oxo-N-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

Name: Name:6-Hydroxy-4-oxo-N-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
Brand: AABLOCKS
SKU: AA01E6EM
Availability: InStock
Rating: 90 (10 reviews)

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5mg

99%

1 week

$273.00 $191.00

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Technical Information
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA01E6EM

Chemical Name:

6-Hydroxy-4-oxo-N-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

CAS Number:

97534-21-9

Molecular Formula:

C11H9N3O3S

Molecular Weight:

263.2725

MDL Number:

MFCD00866337

SMILES:

O=C(C1C(=O)NC(=S)NC1=O)Nc1ccccc1

Properties

Literature

Title: Fortune JM, et, al. Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage. J Biol Chem. 1998 Jul 10;273(28):17643-50.

Title: Brewer AD, et, al. 5-(N-phenylcarboxamido)-2-thiobarbituric acid (NSC 336628), a novel potential antitumor agent. Biochem Pharmacol. 1985 Jun 1;34(11):2047-50.

Title: Cooney DA, et, al. Initial mechanistic studies with merbarone (NSC 336628). Biochem Pharmacol. 1985 Sep 15;34(18):3395-8.

Title: Chen M, et, al. Differences in inhibition of chromosome separation and G2 arrest by DNA topoisomerase II inhibitors merbarone and VM-26. Cancer Res. 1995 Apr 1;55(7):1509-16.

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