98079-52-8,MFCD00214312
Catalog No.:AA00IJYA

98079-52-8 | Lomefloxacin hydrochloride

Pack Size
Purity
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250mg
95%
in stock  
$29.00   $20.00
- +
1g
98%(HPLC)
in stock  
$34.00   $24.00
- +
5g
98%(HPLC)
in stock  
$88.00   $62.00
- +
10g
≥98%
in stock  
$166.00   $116.00
- +
25g
98%(HPLC)
in stock  
$343.00   $240.00
- +
50g
≥98%
in stock  
$669.00   $468.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00IJYA
Chemical Name:
Lomefloxacin hydrochloride
CAS Number:
98079-52-8
Molecular Formula:
C17H19ClF2N3O3
Molecular Weight:
387.8088
MDL Number:
MFCD00214312
SMILES:
CCn1cc(C(=O)O)c(=O)c2c1c(F)c(N1CCNC(C1)C)c(c2)F.[Cl-].[H+]
NSC Number:
758168
Properties
Computed Properties
 
Complexity:
586  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  

Downstream Synthesis Route

[1]Fasani;Mella;Caccia;Tassi;Fagnoni;Albini[ChemicalCommunications,1997,#14,p.1329-1330]

[1]Zhou,You;Xu,Xiaoli;Sun,Yuan;Wang,Huaping;Sun,Haopeng;You,Qidong[BioorganicandMedicinalChemistryLetters,2013,vol.23,#10,p.2974-2978]

[2]CurrentPatentAssignee:NICOXS.A.-US2003/105066,2003,A1

10199-89-0    98079-52-8   
CASUnavailable 

[1]Locationinpatent:experimentalpartUlu,SevgiTatar[EuropeanJournalofMedicinalChemistry,2009,vol.44,#9,p.3402-3405]

[1]Locationinpatent:experimentalpartShu,Zhan;Li,HaiYan;Ma,LinLin;Chen,WeiLiang;Jin,ZhiMin[JournalofChemicalCrystallography,2009,vol.39,#5,p.384-388]

[1]Zhou,You;Xu,Xiaoli;Sun,Yuan;Wang,Huaping;Sun,Haopeng;You,Qidong[BioorganicandMedicinalChemistryLetters,2013,vol.23,#10,p.2974-2978]

Literature

Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.

Journal: Chemical research in toxicology 20150518

Title: Relationship of cellular topoisomerase IIα inhibition to cytotoxicity and published genotoxicity of fluoroquinolone antibiotics in V79 cells.

Journal: Chemico-biological interactions 20130425

Title: Interaction between holo transferrin and HSA-PPIX complex in the presence of lomefloxacin: an evaluation of PPIX aggregation in protein-protein interactions.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101

Title: Spectroscopic study of degradation products of ciprofloxacin, norfloxacin and lomefloxacin formed in ozonated wastewater.

Journal: Water research 20121015

Title: Photoreactivity of fluoroquinolones: nature of aryl cations generated in water.

Journal: Organic letters 20120803

Title: Simultaneous determination of norfloxacin and lomefloxacin in milk by first derivative synchronous fluorescence spectrometry using Al (III) as an enhancer.

Journal: Analytica chimica acta 20111130

Title: Ligational behaviour of lomefloxacin drug towards Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), Th(IV) and UO(2)(VI) ions: synthesis, structural characterization and biological activity studies.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101

Title: Determination of ofloxacin and lomefloxacin in chicken muscle using molecularly imprinted solid-phase extraction coupled with liquid chromatography.

Journal: Journal of separation science 20111001

Title: Interaction study of moxifloxacin and lomefloxacin with co-administered drugs.

Journal: Pakistan journal of pharmaceutical sciences 20110701

Title: Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma.

Journal: Biomedical chromatography : BMC 20110501

Title: Lomefloxacin promotes the interaction between human serum albumin and transferrin: a mechanistic insight into the emergence of antibiotic's side effects.

Journal: Journal of pharmaceutical and biomedical analysis 20110428

Title: Comparison of binding interactions of lomefloxacin to serum albumin and serum transferrin by resonance light scattering and fluorescence quenching methods.

Journal: Journal of biomolecular structure & dynamics 20110201

Title: Ultrasound-assisted dispersive liquid-liquid microextraction for determination of fluoroquinolones in pharmaceutical wastewater.

Journal: Journal of pharmaceutical and biomedical analysis 20110105

Title: [Treatment of prostatic adenoma with concomitant chronic bacterial prostatitis].

Journal: Urologiia (Moscow, Russia : 1999) 20110101

Title: [Administration of vitaprost plus for prevention of infectious-inflammatory complications of transurethral prostatic resection in patients with prostatic adenoma].

Journal: Urologiia (Moscow, Russia : 1999) 20110101

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Protective effects of platinum nanoparticles against UV-light-induced epidermal inflammation.

Journal: Experimental dermatology 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Enantioseparation of lomefloxacin hydrochloride by high-speed counter-current chromatography using sulfated-β-cyclodextrin as a chiral selector.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

Title: [Preliminary study on occurrence and health risk assessment of quinolone antibiotics in vegetables from Guangzhou, China].

Journal: Huan jing ke xue= Huanjing kexue 20101001

Title: Determination of four fluoroquinolone antibiotics in tap water in Guangzhou and Macao.

Journal: Environmental pollution (Barking, Essex : 1987) 20100701

Title: Quorum-sensing regulator sdiA and marA overexpression is involved in in vitro-selected multidrug resistance of Escherichia coli.

Journal: The Journal of antimicrobial chemotherapy 20100601

Title: Comparative study of skin phototoxicity with three drugs by an in vivo mouse model.

Journal: The Journal of toxicological sciences 20100201

Title: Real-time visualization of photochemically induced fluorescence of 8-halogenated quinolones: lomefloxacin, clinafloxacin and Bay3118 in live human HaCaT keratinocytes.

Journal: Photochemistry and photobiology 20100101

Title: [Characteristics of microbiological diagnosis of chronic bacterial prostatitis].

Journal: Urologiia (Moscow, Russia : 1999) 20100101

Title: Validation of a MLC method with fluorescence detection for the determination of quinolones in urine samples by direct injection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091201

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Highly sensitive spectrofluorimetric determination of lomefloxacin in spiked human plasma, urine and pharmaceutical preparations.

Journal: European journal of medicinal chemistry 20090901

Title: Molecular spectroscopy and chemometrics: an analytical study of synergistic effects of drugs--interaction between fluoroquinolones and DNA.

Journal: The Analyst 20090901

Title: Investigation on enhanced chemiluminescence reaction systems with bis(hydrogenperiodato) argentate(III) complex anion for fluoroquinolones synthetic antibiotics.

Journal: Talanta 20090715

Title: Use of centromeric and telomeric DNA probes in in situ hybridization for differentiation of micronuclei induced by lomefloxacin.

Journal: Environmental and molecular mutagenesis 20090601

Title: Late-onset laser in situ keratomileusis-related corneal ulcer--a case series.

Journal: Cornea 20090601

Title: Enhanced separation of seven quinolones by capillary electrophoresis with silica nanoparticles as additive.

Journal: Talanta 20090315

Title: Sonodynamic effects of lomefloxacin derivatives conjugated with methoxy polyethylene glycol on sarcoma 180 cells.

Journal: Anticancer research 20090101

Title: Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: [Vitaprost plus in the treatment of chronic bacterial prostatitis].

Journal: Urologiia (Moscow, Russia : 1999) 20090101

Title: [Efficacy of levofloxacin, lomefloxacin and moxifloxacin vs. other fluoroquinolones in experimental plague due to FI+ and FI- strains of Yersinia pestis in Albino mice].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101

Title: Abatement by naringin of lomefloxacin-induced genomic instability in mice.

Journal: Mutagenesis 20081101

Title: Development and validation of a solid-phase extraction method coupled to liquid chromatography with fluorescence detection for the determination of fluoroquinolone residues in powdered infant formulae. Application to the analysis of samples from the Spanish and Latin American market.

Journal: Journal of chromatography. A 20081031

Title: Postoperative lomefloxacin 0.3% prophylaxis in strabismus surgery.

Journal: Current eye research 20081001

Title: Enrofloxacin-imprinted monolithic columns synthesized using reversible addition-fragmentation chain transfer polymerization.

Journal: Journal of separation science 20080601

Title: Modeling the photochemistry of the reference phototoxic drug lomefloxacin by steady-state and time-resolved experiments, and DFT and post-HF calculations.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: The apical uptake transporter of levofloxacin is distinct from the peptide transporter in human intestinal epithelial Caco-2 cells.

Journal: Drug metabolism and pharmacokinetics 20080101

Title: Separation of seven fluoroquinolones by microemulsion electrokinetic chromatography and application to ciprofloxacin, lomefloxacin determination in urine.

Journal: Journal of chromatography. A 20070907

Title: Corneal critical barrier against the penetration of dexamethasone and lomefloxacin hydrochloride: evaluation by the activation energy for drug partition and diffusion in cornea.

Journal: Drug development and industrial pharmacy 20070801

Title: Penetration of second-, third-, and fourth-generation topical fluoroquinolone into aqueous and vitreous humour in a rabbit endophthalmitis model.

Journal: Eye (London, England) 20070701

Title: [Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20070701

Title: [Preparation of lomefloxacin-Tb3+ nanoparticles modified by PVP via microwave-assistance and its properties of fluorescence].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20070601

Title: Multi-spectroscopic study on interaction of bovine serum albumin with lomefloxacin-copper(II) complex.

Journal: International journal of biological macromolecules 20070310

Title: Minor depression and health status among US adults with diabetes mellitus.

Journal: The American journal of managed care 20070201

Title: Adsorption and oxidation of fluoroquinolone antibacterial agents and structurally related amines with goethite.

Journal: Chemosphere 20070101

Title: Stability indicating methods for the determination of some fluoroquinolones in the presence of their decarboxylated degrades.

Journal: Chemical & pharmaceutical bulletin 20061201

Title: Chiral separation of four fluoroquinolone compounds using capillary electrophoresis with hydroxypropyl-beta-cyclodextrin as chiral selector.

Journal: Journal of chromatography. A 20061020

Title: Photo-chemically induced DNA effects in the comet assay with epidermal cells of SKH-1 mice after a single oral administration of different fluoroquinolones and 8-methoxypsoralen in combination with exposure to UVA.

Journal: Mutation research 20061010

Title: Quinolones for uncomplicated acute cystitis in women.

Journal: The Cochrane database of systematic reviews 20060719

Title: Spectrofluorimetric study on the inclusion interaction between lomefloxacin and p-sulfonated calix[4]arene and its analytical application.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060601

Title: Corneal penetration of simultaneously applied topical levofloxacin, norfloxacin and lomefloxacin in human eyes.

Journal: Acta ophthalmologica Scandinavica 20060401

Title: Effect of fluoroquinolones on plasma glucose levels in fasted and glucose-loaded mice.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20060401

Title: Fluorometric study on the interaction between lomefloxacin and bovine lactoferrin.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060301

Title: [Study on the interaction of lomefloxacin terbium complex and bovine serum albumin by fluorescence spectra].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20060301

Title: Spectrofluorimetric determination of trace heparin using lomefloxacin-terbium probe.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060201

Title: Broad-spectrum sunscreens prevent the secretion of proinflammatory cytokines in human keratinocytes exposed to ultraviolet A and phototoxic lomefloxacin.

Journal: Canadian journal of physiology and pharmacology 20060201

Title: Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20060123

Title: T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060101

Title: [Synchronous fluorimetric determination of the residues of three quinolones in Eel by partial least squares].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20060101

Title: Microbiological assay for lomefloxacin in coated tablets.

Journal: Journal of AOAC International 20060101

Title: Determination of lomefloxacin in tablet preparations by liquid chromatography.

Journal: Journal of AOAC International 20060101

Title: Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro.

Journal: The Journal of parasitology 20051201

Title: Electrochemical adsorptive behavior of some fluoroquinolones at carbon paste electrode.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20051001

Title: The simultaneous separation and determination of five quinolone antibiotics using isocratic reversed-phase HPLC: application to stability studies on an ofloxacin tablet formulation.

Journal: Journal of pharmaceutical and biomedical analysis 20050915

Title: The photocarcinogenesis of antibiotic lomefloxacin and UVA radiation is enhanced in xeroderma pigmentosum group A gene-deficient mice.

Journal: The Journal of investigative dermatology 20050901

Title: In vitro availability of lomefloxacin hydrochloride in presence of essential and trace elements.

Journal: Pakistan journal of pharmaceutical sciences 20050701

Title: Chlamydia trachomatis survival in the presence of two fluoroquinolones (lomefloxacin versus levofloxacin) in patients with chronic prostatitis syndrome.

Journal: Andrologia 20050601

Title: Vibrational spectroscopic characterization of fluoroquinolones.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050501

Title: In vitro activity of fluoroquinolones against Mycobacterium tuberculosis.

Journal: Journal of chemotherapy (Florence, Italy) 20050401

Title: [Antimicrobial susceptibility surveillance of recent isolates from ophthalmological infections to gatifloxacin and other antimicrobial drugs].

Journal: The Japanese journal of antibiotics 20050201

Title: High-throughput mass spectrometer using atmospheric pressure ionization and a cylindrical ion trap array.

Journal: Analytical chemistry 20050115

Title: [Comparative efficiency of treatment with moxyfloxacin and lomefloxacin for generalized murine tuberculosis caused by drug-resistant Mycobacterium strains].

Journal: Problemy tuberkuleza i boleznei legkikh 20050101

Title: Multiresidue determination of eleven quinolones in milk by liquid chromatography with fluorescence detection.

Journal: Journal of AOAC International 20050101

Title: [Fluorescence spectroscopy determination of lomefloxacin by charge transfer complex formation with chloranilic acid].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20041201

Title: [Simultaneous determination of quinolones in foods by LC/MS/MS].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20041001

Title: Clinical evaluation of ophthalmic lomefloxacin 0.3% in comparison with fortified cefazolin and gentamicin ophthalmic solutions in the treatment of presumed bacterial keratitis.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040901

Title: Levofloxacin in the treatment of urinary tract infections and prostatitis.

Journal: Journal of chemotherapy (Florence, Italy) 20040401

Title: Comparison of topical lomefloxacin 0.3 per cent versus topical ciprofloxacin 0.3 per cent for the treatment of presumed bacterial corneal ulcers.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040301

Title: Compare two methods of measuring DNA damage induced by photogenotoxicity of fluoroquinolones.

Journal: Acta pharmacologica Sinica 20040201

Title: Molecular responses to photogenotoxic stress induced by the antibiotic lomefloxacin in human skin cells: from DNA damage to apoptosis.

Journal: The Journal of investigative dermatology 20030901

Title: Aqueous humor levels of topically applied levofloxacin, norfloxacin, and lomefloxacin in the same human eyes.

Journal: Journal of cataract and refractive surgery 20030901

Title: [Analysis of the response factors of different quinolones detected by evaporative light-scattering detector].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20030901

Title: Binding characteristics of fluoroquinolones to synthetic levodopa melanin.

Journal: The Journal of pharmacy and pharmacology 20030801

Title: Effects of lomefloxacin and norfloxacin on pancreatic beta-cell ATP-sensitive K(+) channels.

Journal: Life sciences 20030613

Title: Reliability of phototoxic tests of fluoroquinolones in vitro.

Journal: Acta pharmacologica Sinica 20030501

Title: Genotoxicity of lomefloxacin--an antibacterial drug in somatic and germ cells of Swiss albino mice in vivo.

Journal: Mutation research 20030205

Title: Photocarcinogenesis in the Tg.AC mouse: lomefloxacin and 8-methoxypsoralen.

Journal: Photochemistry and photobiology 20030101

Title: [Levofloxacin (Tavanic) in the treatment of corneal ulcers].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: Determination of lomefloxacin by terbium sensitized chemiluminescence method.

Journal: Analytical and bioanalytical chemistry 20021201

Title: Determination of bioequivalence of lomefloxacin tablets using urinary excretion data.

Journal: Journal of pharmaceutical and biomedical analysis 20021107

Title: Laser flash photolysis study of photoionization in fluoroquinolones.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021101

Title: In vivo photochemical micronucleus induction due to certain quinolone antimicrobial agents in the skin of hairless mice.

Journal: Mutation research 20020926

Title: The expanding role of fluoroquinolones.

Journal: The American journal of medicine 20020708

Title: Lomefloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis.

Journal: International journal of antimicrobial agents 20020701

Title: [Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies].

Journal: The Japanese journal of antibiotics 20020601

Title: [Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration].

Journal: The Japanese journal of antibiotics 20020601

Title: [Study on the direct determination of lomefloxacin in urine by derivative-synchronous fluorescence].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20020601

Title: Ultrastructural characterization of murine limb buds after in vitro exposure to grepafloxacin and other fluoroquinolones.

Journal: Archives of toxicology 20020101

Title: [Lemofloxacin: antimicrobial ability and clinico-pharmacokinetic basis for use in urogenital infections].

Journal: Urologiia (Moscow, Russia : 1999) 20020101

Title: Accumulation of ciprofloxacin and lomefloxacinin fluoroquinolone-resistant strains of Escherichia coli.

Journal: Chinese medical journal 20020101

Title: Safety and effectiveness of lomefloxacin in patients with acute exacerbation of chronic bronchitis (AECB) chronically treated with oral theophyllines.

Journal: Journal of chemotherapy (Florence, Italy) 20011201

Title: Disposable 1-day Acuvue contact lenses for the delivery of lomefloxacin to rabbits' eyes.

Journal: The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc 20011001

Title: Studies on the uptake and release of fluoroquinolones by disposable contact lenses.

Journal: The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc 20011001

Title: Determination of lomefloxacin, an antibacterial drug, in pharmaceutical preparations based on its polarographic catalytic wave in the presence of 2-iodoacetamide.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20011001

Title: Differential-pulse adsorptive stripping voltammetric determination of the antibacterial lomefloxacin.

Journal: Journal of pharmaceutical and biomedical analysis 20010801

Title: Pulmonary disposition of lomefloxacin in patients with acute exacerbation of chronic obstructive pulmonary disease. A multiple-dose study.

Journal: Journal of chemotherapy (Florence, Italy) 20010801

Title: Multifaceted photoreactivity of 6-fluoro-7-aminoquinolones from the lowest excited states in aqueous media: a study by nanosecond and picosecond spectroscopic techniques.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20010518

Title: Simple high-performance liquid chromatographic assay for the determination of ciprofloxacin in human plasma with ultraviolet detection.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010505

Title: Fluoroquinolones as chemical tools to define a strategy for photogenotoxicity in vitro assessment.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20010401

Title: Lomefloxacin is an effective treatment of experimental bacterial keratitis.

Journal: Cornea 20010401

Title: [Study on photodegradation kinetics of lomefloxacin hydrochloride aqueous solution].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010301

Title: The role of lomefloxacin in the treatment of chronic prostatitis.

Journal: Journal of chemotherapy (Florence, Italy) 20010201

Title: Unusual cause of hematuria.

Journal: Urologia internationalis 20010101

Title: Sequence-specific DNA damage induced by UVA radiation in the presence of endogenous and exogenous photosensitizers.

Journal: Current problems in dermatology 20010101

Title: Voltammetric behavior and analytical applications of lomefloxacin, an antibacterial fluorquinolone.

Journal: Journal of AOAC International 20010101

Title: Possible relationship between phototoxicity and photodegradation of sitafloxacin, a quinolone antibacterial agent, in the auricular skin of albino mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20000801

Title: Minimal inhibitory concentrations of lomefloxacin and minocycline against drug-sensitive and drug-resistant isolates of M. tuberculosis compared on L-J and 7H11 media.

Journal: International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 19970901

Title: [Bactericidal effects of maxaquin on mycobacterium tuberculosis].

Journal: Problemy tuberkuleza 19970101

Title: [Long-term monitoring of female acute uncomplicated cystitis cases after lomefloxacin single-dose therapy].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 19950101

Title: In vitro activity of the new quinolone lomefloxacin against Mycobacterium tuberculosis.

Journal: The American review of respiratory disease 19921201

Title: In-vitro activity of lomefloxacin against pathogenic and environmental mycobacteria.

Journal: The Journal of antimicrobial chemotherapy 19920801

Title: Hoogkamp-Korstanje JA. In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections. J Antimicrob Chemother. 1997 Sep;40(3):427-31.

Title: Reem I Al-Wabli. Lomefloxacin. Profiles Drug Subst Excip Relat Methodol. 2017;42:193-240.

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SDS
Tags:98079-52-8 Molecular Formula|98079-52-8 MDL|98079-52-8 SMILES|98079-52-8 Lomefloxacin hydrochloride
Catalog No.: AA00IJYA
98079-52-8,MFCD00214312
98079-52-8 | Lomefloxacin hydrochloride
Pack Size: 250mg
Purity: 95%
in stock
$29.00 $20.00
Pack Size: 1g
Purity: 98%(HPLC)
in stock
$34.00 $24.00
Pack Size: 5g
Purity: 98%(HPLC)
in stock
$88.00 $62.00
Pack Size: 10g
Purity: ≥98%
in stock
$166.00 $116.00
Pack Size: 25g
Purity: 98%(HPLC)
in stock
$343.00 $240.00
Pack Size: 50g
Purity: ≥98%
in stock
$669.00 $468.00
Quantity
- +
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Technical Information
Catalog Number: AA00IJYA
Chemical Name: Lomefloxacin hydrochloride
CAS Number: 98079-52-8
Molecular Formula: C17H19ClF2N3O3
Molecular Weight: 387.8088
MDL Number: MFCD00214312
SMILES: CCn1cc(C(=O)O)c(=O)c2c1c(F)c(N1CCNC(C1)C)c(c2)F.[Cl-].[H+]
NSC Number: 758168
Properties
Complexity: 586  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 26  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
Downstream Synthesis Route
98079-52-8    111234-01-6 

[1]Fasani;Mella;Caccia;Tassi;Fagnoni;Albini[ChemicalCommunications,1997,#14,p.1329-1330]

24424-99-5    98079-52-8    1432044-64-8 

[1]Zhou,You;Xu,Xiaoli;Sun,Yuan;Wang,Huaping;Sun,Haopeng;You,Qidong[BioorganicandMedicinalChemistryLetters,2013,vol.23,#10,p.2974-2978]

[2]CurrentPatentAssignee:NICOXS.A.-US2003/105066,2003,A1

10199-89-0    98079-52-8   
CASUnavailable 

[1]Locationinpatent:experimentalpartUlu,SevgiTatar[EuropeanJournalofMedicinalChemistry,2009,vol.44,#9,p.3402-3405]

98079-52-8    98079-51-7 

[1]Locationinpatent:experimentalpartShu,Zhan;Li,HaiYan;Ma,LinLin;Chen,WeiLiang;Jin,ZhiMin[JournalofChemicalCrystallography,2009,vol.39,#5,p.384-388]

98079-52-8    1432044-76-2 

[1]Zhou,You;Xu,Xiaoli;Sun,Yuan;Wang,Huaping;Sun,Haopeng;You,Qidong[BioorganicandMedicinalChemistryLetters,2013,vol.23,#10,p.2974-2978]

Literature fold

Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.

Journal: Chemical research in toxicology20150518

Title: Relationship of cellular topoisomerase IIα inhibition to cytotoxicity and published genotoxicity of fluoroquinolone antibiotics in V79 cells.

Journal: Chemico-biological interactions20130425

Title: Interaction between holo transferrin and HSA-PPIX complex in the presence of lomefloxacin: an evaluation of PPIX aggregation in protein-protein interactions.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20121101

Title: Spectroscopic study of degradation products of ciprofloxacin, norfloxacin and lomefloxacin formed in ozonated wastewater.

Journal: Water research20121015

Title: Photoreactivity of fluoroquinolones: nature of aryl cations generated in water.

Journal: Organic letters20120803

Title: Simultaneous determination of norfloxacin and lomefloxacin in milk by first derivative synchronous fluorescence spectrometry using Al (III) as an enhancer.

Journal: Analytica chimica acta20111130

Title: Ligational behaviour of lomefloxacin drug towards Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), Th(IV) and UO(2)(VI) ions: synthesis, structural characterization and biological activity studies.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20111101

Title: Determination of ofloxacin and lomefloxacin in chicken muscle using molecularly imprinted solid-phase extraction coupled with liquid chromatography.

Journal: Journal of separation science20111001

Title: Interaction study of moxifloxacin and lomefloxacin with co-administered drugs.

Journal: Pakistan journal of pharmaceutical sciences20110701

Title: Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma.

Journal: Biomedical chromatography : BMC20110501

Title: Lomefloxacin promotes the interaction between human serum albumin and transferrin: a mechanistic insight into the emergence of antibiotic's side effects.

Journal: Journal of pharmaceutical and biomedical analysis20110428

Title: Comparison of binding interactions of lomefloxacin to serum albumin and serum transferrin by resonance light scattering and fluorescence quenching methods.

Journal: Journal of biomolecular structure & dynamics20110201

Title: Ultrasound-assisted dispersive liquid-liquid microextraction for determination of fluoroquinolones in pharmaceutical wastewater.

Journal: Journal of pharmaceutical and biomedical analysis20110105

Title: [Treatment of prostatic adenoma with concomitant chronic bacterial prostatitis].

Journal: Urologiia (Moscow, Russia : 1999)20110101

Title: [Administration of vitaprost plus for prevention of infectious-inflammatory complications of transurethral prostatic resection in patients with prostatic adenoma].

Journal: Urologiia (Moscow, Russia : 1999)20110101

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals20101201

Title: Protective effects of platinum nanoparticles against UV-light-induced epidermal inflammation.

Journal: Experimental dermatology20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Enantioseparation of lomefloxacin hydrochloride by high-speed counter-current chromatography using sulfated-β-cyclodextrin as a chiral selector.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20101015

Title: [Preliminary study on occurrence and health risk assessment of quinolone antibiotics in vegetables from Guangzhou, China].

Journal: Huan jing ke xue= Huanjing kexue20101001

Title: Determination of four fluoroquinolone antibiotics in tap water in Guangzhou and Macao.

Journal: Environmental pollution (Barking, Essex : 1987)20100701

Title: Quorum-sensing regulator sdiA and marA overexpression is involved in in vitro-selected multidrug resistance of Escherichia coli.

Journal: The Journal of antimicrobial chemotherapy20100601

Title: Comparative study of skin phototoxicity with three drugs by an in vivo mouse model.

Journal: The Journal of toxicological sciences20100201

Title: Real-time visualization of photochemically induced fluorescence of 8-halogenated quinolones: lomefloxacin, clinafloxacin and Bay3118 in live human HaCaT keratinocytes.

Journal: Photochemistry and photobiology20100101

Title: [Characteristics of microbiological diagnosis of chronic bacterial prostatitis].

Journal: Urologiia (Moscow, Russia : 1999)20100101

Title: Validation of a MLC method with fluorescence detection for the determination of quinolones in urine samples by direct injection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20091201

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology20091001

Title: Highly sensitive spectrofluorimetric determination of lomefloxacin in spiked human plasma, urine and pharmaceutical preparations.

Journal: European journal of medicinal chemistry20090901

Title: Molecular spectroscopy and chemometrics: an analytical study of synergistic effects of drugs--interaction between fluoroquinolones and DNA.

Journal: The Analyst20090901

Title: Investigation on enhanced chemiluminescence reaction systems with bis(hydrogenperiodato) argentate(III) complex anion for fluoroquinolones synthetic antibiotics.

Journal: Talanta20090715

Title: Use of centromeric and telomeric DNA probes in in situ hybridization for differentiation of micronuclei induced by lomefloxacin.

Journal: Environmental and molecular mutagenesis20090601

Title: Late-onset laser in situ keratomileusis-related corneal ulcer--a case series.

Journal: Cornea20090601

Title: Enhanced separation of seven quinolones by capillary electrophoresis with silica nanoparticles as additive.

Journal: Talanta20090315

Title: Sonodynamic effects of lomefloxacin derivatives conjugated with methoxy polyethylene glycol on sarcoma 180 cells.

Journal: Anticancer research20090101

Title: Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.

Journal: Drug metabolism and pharmacokinetics20090101

Title: [Vitaprost plus in the treatment of chronic bacterial prostatitis].

Journal: Urologiia (Moscow, Russia : 1999)20090101

Title: [Efficacy of levofloxacin, lomefloxacin and moxifloxacin vs. other fluoroquinolones in experimental plague due to FI+ and FI- strains of Yersinia pestis in Albino mice].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]20090101

Title: Abatement by naringin of lomefloxacin-induced genomic instability in mice.

Journal: Mutagenesis20081101

Title: Development and validation of a solid-phase extraction method coupled to liquid chromatography with fluorescence detection for the determination of fluoroquinolone residues in powdered infant formulae. Application to the analysis of samples from the Spanish and Latin American market.

Journal: Journal of chromatography. A20081031

Title: Postoperative lomefloxacin 0.3% prophylaxis in strabismus surgery.

Journal: Current eye research20081001

Title: Enrofloxacin-imprinted monolithic columns synthesized using reversible addition-fragmentation chain transfer polymerization.

Journal: Journal of separation science20080601

Title: Modeling the photochemistry of the reference phototoxic drug lomefloxacin by steady-state and time-resolved experiments, and DFT and post-HF calculations.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20080101

Title: The apical uptake transporter of levofloxacin is distinct from the peptide transporter in human intestinal epithelial Caco-2 cells.

Journal: Drug metabolism and pharmacokinetics20080101

Title: Separation of seven fluoroquinolones by microemulsion electrokinetic chromatography and application to ciprofloxacin, lomefloxacin determination in urine.

Journal: Journal of chromatography. A20070907

Title: Corneal critical barrier against the penetration of dexamethasone and lomefloxacin hydrochloride: evaluation by the activation energy for drug partition and diffusion in cornea.

Journal: Drug development and industrial pharmacy20070801

Title: Penetration of second-, third-, and fourth-generation topical fluoroquinolone into aqueous and vitreous humour in a rabbit endophthalmitis model.

Journal: Eye (London, England)20070701

Title: [Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].

Journal: Se pu = Chinese journal of chromatography20070701

Title: [Preparation of lomefloxacin-Tb3+ nanoparticles modified by PVP via microwave-assistance and its properties of fluorescence].

Journal: Guang pu xue yu guang pu fen xi = Guang pu20070601

Title: Multi-spectroscopic study on interaction of bovine serum albumin with lomefloxacin-copper(II) complex.

Journal: International journal of biological macromolecules20070310

Title: Minor depression and health status among US adults with diabetes mellitus.

Journal: The American journal of managed care20070201

Title: Adsorption and oxidation of fluoroquinolone antibacterial agents and structurally related amines with goethite.

Journal: Chemosphere20070101

Title: Stability indicating methods for the determination of some fluoroquinolones in the presence of their decarboxylated degrades.

Journal: Chemical & pharmaceutical bulletin20061201

Title: Chiral separation of four fluoroquinolone compounds using capillary electrophoresis with hydroxypropyl-beta-cyclodextrin as chiral selector.

Journal: Journal of chromatography. A20061020

Title: Photo-chemically induced DNA effects in the comet assay with epidermal cells of SKH-1 mice after a single oral administration of different fluoroquinolones and 8-methoxypsoralen in combination with exposure to UVA.

Journal: Mutation research20061010

Title: Quinolones for uncomplicated acute cystitis in women.

Journal: The Cochrane database of systematic reviews20060719

Title: Spectrofluorimetric study on the inclusion interaction between lomefloxacin and p-sulfonated calix[4]arene and its analytical application.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20060601

Title: Corneal penetration of simultaneously applied topical levofloxacin, norfloxacin and lomefloxacin in human eyes.

Journal: Acta ophthalmologica Scandinavica20060401

Title: Effect of fluoroquinolones on plasma glucose levels in fasted and glucose-loaded mice.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy20060401

Title: Fluorometric study on the interaction between lomefloxacin and bovine lactoferrin.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20060301

Title: [Study on the interaction of lomefloxacin terbium complex and bovine serum albumin by fluorescence spectra].

Journal: Guang pu xue yu guang pu fen xi = Guang pu20060301

Title: Spectrofluorimetric determination of trace heparin using lomefloxacin-terbium probe.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20060201

Title: Broad-spectrum sunscreens prevent the secretion of proinflammatory cytokines in human keratinocytes exposed to ultraviolet A and phototoxic lomefloxacin.

Journal: Canadian journal of physiology and pharmacology20060201

Title: Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis20060123

Title: T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20060101

Title: [Synchronous fluorimetric determination of the residues of three quinolones in Eel by partial least squares].

Journal: Guang pu xue yu guang pu fen xi = Guang pu20060101

Title: Microbiological assay for lomefloxacin in coated tablets.

Journal: Journal of AOAC International20060101

Title: Determination of lomefloxacin in tablet preparations by liquid chromatography.

Journal: Journal of AOAC International20060101

Title: Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro.

Journal: The Journal of parasitology20051201

Title: Electrochemical adsorptive behavior of some fluoroquinolones at carbon paste electrode.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20051001

Title: The simultaneous separation and determination of five quinolone antibiotics using isocratic reversed-phase HPLC: application to stability studies on an ofloxacin tablet formulation.

Journal: Journal of pharmaceutical and biomedical analysis20050915

Title: The photocarcinogenesis of antibiotic lomefloxacin and UVA radiation is enhanced in xeroderma pigmentosum group A gene-deficient mice.

Journal: The Journal of investigative dermatology20050901

Title: In vitro availability of lomefloxacin hydrochloride in presence of essential and trace elements.

Journal: Pakistan journal of pharmaceutical sciences20050701

Title: Chlamydia trachomatis survival in the presence of two fluoroquinolones (lomefloxacin versus levofloxacin) in patients with chronic prostatitis syndrome.

Journal: Andrologia20050601

Title: Vibrational spectroscopic characterization of fluoroquinolones.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20050501

Title: In vitro activity of fluoroquinolones against Mycobacterium tuberculosis.

Journal: Journal of chemotherapy (Florence, Italy)20050401

Title: [Antimicrobial susceptibility surveillance of recent isolates from ophthalmological infections to gatifloxacin and other antimicrobial drugs].

Journal: The Japanese journal of antibiotics20050201

Title: High-throughput mass spectrometer using atmospheric pressure ionization and a cylindrical ion trap array.

Journal: Analytical chemistry20050115

Title: [Comparative efficiency of treatment with moxyfloxacin and lomefloxacin for generalized murine tuberculosis caused by drug-resistant Mycobacterium strains].

Journal: Problemy tuberkuleza i boleznei legkikh20050101

Title: Multiresidue determination of eleven quinolones in milk by liquid chromatography with fluorescence detection.

Journal: Journal of AOAC International20050101

Title: [Fluorescence spectroscopy determination of lomefloxacin by charge transfer complex formation with chloranilic acid].

Journal: Guang pu xue yu guang pu fen xi = Guang pu20041201

Title: [Simultaneous determination of quinolones in foods by LC/MS/MS].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan20041001

Title: Clinical evaluation of ophthalmic lomefloxacin 0.3% in comparison with fortified cefazolin and gentamicin ophthalmic solutions in the treatment of presumed bacterial keratitis.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet20040901

Title: Levofloxacin in the treatment of urinary tract infections and prostatitis.

Journal: Journal of chemotherapy (Florence, Italy)20040401

Title: Comparison of topical lomefloxacin 0.3 per cent versus topical ciprofloxacin 0.3 per cent for the treatment of presumed bacterial corneal ulcers.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet20040301

Title: Compare two methods of measuring DNA damage induced by photogenotoxicity of fluoroquinolones.

Journal: Acta pharmacologica Sinica20040201

Title: Molecular responses to photogenotoxic stress induced by the antibiotic lomefloxacin in human skin cells: from DNA damage to apoptosis.

Journal: The Journal of investigative dermatology20030901

Title: Aqueous humor levels of topically applied levofloxacin, norfloxacin, and lomefloxacin in the same human eyes.

Journal: Journal of cataract and refractive surgery20030901

Title: [Analysis of the response factors of different quinolones detected by evaporative light-scattering detector].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20030901

Title: Binding characteristics of fluoroquinolones to synthetic levodopa melanin.

Journal: The Journal of pharmacy and pharmacology20030801

Title: Effects of lomefloxacin and norfloxacin on pancreatic beta-cell ATP-sensitive K(+) channels.

Journal: Life sciences20030613

Title: Reliability of phototoxic tests of fluoroquinolones in vitro.

Journal: Acta pharmacologica Sinica20030501

Title: Genotoxicity of lomefloxacin--an antibacterial drug in somatic and germ cells of Swiss albino mice in vivo.

Journal: Mutation research20030205

Title: Photocarcinogenesis in the Tg.AC mouse: lomefloxacin and 8-methoxypsoralen.

Journal: Photochemistry and photobiology20030101

Title: [Levofloxacin (Tavanic) in the treatment of corneal ulcers].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]20030101

Title: Determination of lomefloxacin by terbium sensitized chemiluminescence method.

Journal: Analytical and bioanalytical chemistry20021201

Title: Determination of bioequivalence of lomefloxacin tablets using urinary excretion data.

Journal: Journal of pharmaceutical and biomedical analysis20021107

Title: Laser flash photolysis study of photoionization in fluoroquinolones.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology20021101

Title: In vivo photochemical micronucleus induction due to certain quinolone antimicrobial agents in the skin of hairless mice.

Journal: Mutation research20020926

Title: The expanding role of fluoroquinolones.

Journal: The American journal of medicine20020708

Title: Lomefloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis.

Journal: International journal of antimicrobial agents20020701

Title: [Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies].

Journal: The Japanese journal of antibiotics20020601

Title: [Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration].

Journal: The Japanese journal of antibiotics20020601

Title: [Study on the direct determination of lomefloxacin in urine by derivative-synchronous fluorescence].

Journal: Guang pu xue yu guang pu fen xi = Guang pu20020601

Title: Ultrastructural characterization of murine limb buds after in vitro exposure to grepafloxacin and other fluoroquinolones.

Journal: Archives of toxicology20020101

Title: [Lemofloxacin: antimicrobial ability and clinico-pharmacokinetic basis for use in urogenital infections].

Journal: Urologiia (Moscow, Russia : 1999)20020101

Title: Accumulation of ciprofloxacin and lomefloxacinin fluoroquinolone-resistant strains of Escherichia coli.

Journal: Chinese medical journal20020101

Title: Safety and effectiveness of lomefloxacin in patients with acute exacerbation of chronic bronchitis (AECB) chronically treated with oral theophyllines.

Journal: Journal of chemotherapy (Florence, Italy)20011201

Title: Disposable 1-day Acuvue contact lenses for the delivery of lomefloxacin to rabbits' eyes.

Journal: The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc20011001

Title: Studies on the uptake and release of fluoroquinolones by disposable contact lenses.

Journal: The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc20011001

Title: Determination of lomefloxacin, an antibacterial drug, in pharmaceutical preparations based on its polarographic catalytic wave in the presence of 2-iodoacetamide.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20011001

Title: Differential-pulse adsorptive stripping voltammetric determination of the antibacterial lomefloxacin.

Journal: Journal of pharmaceutical and biomedical analysis20010801

Title: Pulmonary disposition of lomefloxacin in patients with acute exacerbation of chronic obstructive pulmonary disease. A multiple-dose study.

Journal: Journal of chemotherapy (Florence, Italy)20010801

Title: Multifaceted photoreactivity of 6-fluoro-7-aminoquinolones from the lowest excited states in aqueous media: a study by nanosecond and picosecond spectroscopic techniques.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20010518

Title: Simple high-performance liquid chromatographic assay for the determination of ciprofloxacin in human plasma with ultraviolet detection.

Journal: Journal of chromatography. B, Biomedical sciences and applications20010505

Title: Fluoroquinolones as chemical tools to define a strategy for photogenotoxicity in vitro assessment.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20010401

Title: Lomefloxacin is an effective treatment of experimental bacterial keratitis.

Journal: Cornea20010401

Title: [Study on photodegradation kinetics of lomefloxacin hydrochloride aqueous solution].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20010301

Title: The role of lomefloxacin in the treatment of chronic prostatitis.

Journal: Journal of chemotherapy (Florence, Italy)20010201

Title: Unusual cause of hematuria.

Journal: Urologia internationalis20010101

Title: Sequence-specific DNA damage induced by UVA radiation in the presence of endogenous and exogenous photosensitizers.

Journal: Current problems in dermatology20010101

Title: Voltammetric behavior and analytical applications of lomefloxacin, an antibacterial fluorquinolone.

Journal: Journal of AOAC International20010101

Title: Possible relationship between phototoxicity and photodegradation of sitafloxacin, a quinolone antibacterial agent, in the auricular skin of albino mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20000801

Title: Minimal inhibitory concentrations of lomefloxacin and minocycline against drug-sensitive and drug-resistant isolates of M. tuberculosis compared on L-J and 7H11 media.

Journal: International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association19970901

Title: [Bactericidal effects of maxaquin on mycobacterium tuberculosis].

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Title: [Long-term monitoring of female acute uncomplicated cystitis cases after lomefloxacin single-dose therapy].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases19950101

Title: In vitro activity of the new quinolone lomefloxacin against Mycobacterium tuberculosis.

Journal: The American review of respiratory disease19921201

Title: In-vitro activity of lomefloxacin against pathogenic and environmental mycobacteria.

Journal: The Journal of antimicrobial chemotherapy19920801

Title: Hoogkamp-Korstanje JA. In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections. J Antimicrob Chemother. 1997 Sep;40(3):427-31.

Title: Reem I Al-Wabli. Lomefloxacin. Profiles Drug Subst Excip Relat Methodol. 2017;42:193-240.

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