Home Other Building Blocks 99-32-1
99-32-1,MFCD00149433
Catalog No.:AA003OP3

99-32-1 | Chelidonic acid

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Purity
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Price(USD)
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250mg
95%
in stock  
$12.00   $8.00
- +
1g
95%
in stock  
$17.00   $12.00
- +
5g
95%
in stock  
$56.00   $39.00
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10g
97%
in stock  
$102.00   $71.00
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25g
97%
in stock  
$198.00   $139.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003OP3
Chemical Name:
Chelidonic acid
CAS Number:
99-32-1
Molecular Formula:
C7H4O6
Molecular Weight:
184.1031
MDL Number:
MFCD00149433
SMILES:
OC(=O)c1oc(cc(=O)c1)C(=O)O
NSC Number:
3979
Properties
Properties
 
BP:
471.3 °C at 760 mmHg  
Form:
Solid  
MP:
265 °C (dec.)(lit.)  
Refractive Index:
1.5600 (estimate)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
316  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
-0.4  

Upstream Synthesis Route

[1]BulletindelaSocieteChimiquedeFrance,1950,p.40,42

[1]SyntheticCommunications,1992,vol.22,#5,p.755-759

[2]Tetrahedron,2000,vol.56,#31,p.5687-5698

[3]BulletindelaSocieteChimiquedeFrance,1950,p.40,42

[4]SpectrochimicaActa,PartA:MolecularandBiomolecularSpectroscopy,1986,vol.42,#4,p.473-486

[1]BulletindelaSocieteChimiquedeFrance,1950,p.40,42

[1]JournalofOrganicChemistry,1958,vol.23,p.1030

[1]JournalofOrganicChemistry,1958,vol.23,p.1030

Downstream Synthesis Route

[1]SyntheticCommunications,1992,vol.22,p.755-759

[2]Tetrahedron,2000,vol.56,p.5687-5698

[3]BulletindelaSocieteChimiquedeFrance,1950,p.40,42

[4]SpectrochimicaActaPartA:MolecularandBiomolecularSpectroscopy,1986,vol.42,p.473-486

[1]MonatsheftefurChemie,1885,vol.6,p.281

[1]Gan,Xin-Min;Paine,RobertT.;Duesler,EileenN.;Noeth,Heinrich[DaltonTransactions,2003,#1,p.153-159]

[2]Terazzi,Emmanuel;Zaïm,Amir;Bocquet,Bernard;Varin,Johan;Guénée,Laure;Dutronc,Thibault;Lemonnier,Jean-François;Floquet,Sébastien;Cadot,Emmanuel;Heinrich,Benoît;Donnio,Bertrand;Piguet,Claude[EuropeanJournalofInorganicChemistry,2013,vol.19,p.3323-3333]

[3]Alves,Filipe;Golesorkhi,Bahman;Guénée,Laure;Naseri,Soroush;Nozary,Homayoun;Piguet,Claude;Taarit,Inès[JournaloftheAmericanChemicalSociety,2021,vol.143,#37,p.15326-15334]

[4]Locationinpatent:experimentalpartBattilocchio,Claudio;Baumann,Marcus;Baxendale,IanR.;Biava,Mariangela;Kitching,MatthewO.;Ley,StevenV.;Martin,RainerE.;Ohnmacht,StephanA.;Tappin,NicholasD.C.[Synthesis,2012,vol.44,#4,p.635-647]

[5]Haitinger;Lieben[MonatsheftefurChemie,1885,vol.6,p.281]Lerch[MonatsheftefurChemie,1884,vol.5,p.383]Lietzenmayer[Dissertation<Erlangen1878>,S.43]

[6]Ong,WeiQiang;Zhao,Huaiqing;Fang,Xiao;Woen,Susanto;Zhou,Feng;Yap,Weiliang;Su,Haibin;Li,SamF.Y.;Zeng,Huaqiang[OrganicLetters,2011,vol.13,#12,p.3194-3197]

[7]Locationinpatent:schemeortableZhao,Huaiqing;Ong,WeiQiang;Fang,Xiao;Zhou,Feng;Hii,MengNi;Li,SamFongYau;Su,Haibin;Zeng,Huaqiang[OrganicandBiomolecularChemistry,2012,vol.10,#6,p.1172-1180]

[8]Wang,Zhenhua;Fan,Wenru;Tong,Rui;Lu,Xili;Xia,Hesheng[RSCAdvances,2014,vol.4,#49,p.25486-25493]

[9]Besnard,Céline;Guénée,Laure;Mirzakhani,Mohsen;Naseri,Soroush;Nozary,Homayoun;Piguet,Claude[InorganicChemistry,2021,vol.60,#20,p.15529-15542]

[1]JournalofHeterocyclicChemistry,1988,vol.25,p.1689-1695

99-32-1   
copperpowder 
  108-97-4 

[1]ChemischeBerichte,1904,vol.37,p.3745    ChemischeBerichte,1905,vol.38,p.1465

Literature

Title: The therapeutic effect of chelidonic acid on ulcerative colitis.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Inhibitory effects of chelidonic acid on IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells.

Journal: Immunopharmacology and immunotoxicology 20111201

Title: Statistically disordered short hydrogen bonds in (pipzH2)(cdoH)2 and a comparison with (pipzH2)(cdo)·H2O (pipz is piperazine and cdoH2 is chelidonic acid).

Journal: Acta crystallographica. Section C, Crystal structure communications 20110401

Title: Beneficial effects of chelidonic acid on a model of allergic rhinitis.

Journal: International immunopharmacology 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Cationic, neutral and anionic metal(II) complexes derived from 4-oxo-4H-pyran-2,6-dicarboxylic acid (chelidonic acid).

Journal: Acta crystallographica. Section C, Crystal structure communications 20070501

Title: Effect of mucilage from yam on activation of lymphocytic immune cells.

Journal: Nutrition research and practice 20070101

Title: Tracer studies with 13C-labeled carbohydrates in cultured plant cells. Retrobiosynthetic analysis of chelidonic acid biosynthesis.

Journal: Phytochemistry 20010501

Title: Shin HJ, et al. Inhibitory effects of chelidonic acid on IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells. Immunopharmacol Immunotoxicol. 2011 Dec;33(4):614-9.

Title: Porter TG, et al. Chelidonic acid and other conformationally restricted substrate analogues as inhibitors of rat brain glutamate decarboxylase. Biochem Pharmacol. 1985 Dec 1;34(23):4145-50.

Title: Oh HA, et al. Beneficial effects of chelidonic acid on a model of allergic rhinitis. Send to Int Immunopharmacol. 2011 Jan;11(1):39-45.

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