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99590-86-0,MFCD00077339
Catalog No.:AA0064TR

99590-86-0 | Bis(acetoxymethyl) 3,12-bis(2-(acetoxymethoxy)-2-oxoethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioate

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10mg
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA0064TR
Chemical Name:
Bis(acetoxymethyl) 3,12-bis(2-(acetoxymethoxy)-2-oxoethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioate
CAS Number:
99590-86-0
Molecular Formula:
C26H40N2O18
Molecular Weight:
668.5984
MDL Number:
MFCD00077339
SMILES:
O=C(CN(CC(=O)OCOC(=O)C)CCOCCOCCN(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCOC(=O)C
Properties
Computed Properties
 
Complexity:
857  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
46  
Hydrogen Bond Acceptor Count:
20  
Rotatable Bond Count:
33  
XLogP3:
-0.4  

Literature

Title: VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission.

Journal: Nature neuroscience 20120501

Title: Role of stored calcium in the regulation of neurotransmitter quantum size.

Journal: Bulletin of experimental biology and medicine 20120201

Title: ATP signalling is crucial for the response of human keratinocytes to mechanical stimulation by hypo-osmotic shock.

Journal: Experimental dermatology 20110501

Title: The Ca2+-dependent phosphatase calcineurin controls the formation of the Carma1-Bcl10-Malt1 complex during T cell receptor-induced NF-kappaB activation.

Journal: The Journal of biological chemistry 20110304

Title: Ca(2+)-dependent enhancement of release by subthreshold somatic depolarization.

Journal: Nature neuroscience 20110101

Title: Effect of fast and slow calcium buffers on induced secretion of neurotransmitter.

Journal: Bulletin of experimental biology and medicine 20100901

Title: Luminal Ca(2+) content regulates intracellular Ca(2+) release in subepicardial myocytes of intact beating mouse hearts: effect of exogenous buffers.

Journal: American journal of physiology. Heart and circulatory physiology 20100601

Title: Asynchronous release of GABA via tonic cannabinoid receptor activation at identified interneuron synapses in rat CA1.

Journal: The European journal of neuroscience 20100401

Title: The involvement of intracellular calcium in the MCT-mediated uptake of lactic acid by HeLa cells.

Journal: Molecular pharmaceutics 20100201

Title: Increase in cytosolic calcium maintains plasma membrane integrity through the formation of microtubule ring structure in apoptotic cervical cancer cells induced by trichosanthin.

Journal: Cell biology international 20091101

Title: Ca(2+) regulation of endocochlear potential in marginal cells.

Journal: The journal of physiological sciences : JPS 20090901

Title: Inhibitory regulation of electrically coupled neurons in the inferior olive is mediated by asynchronous release of GABA.

Journal: Neuron 20090528

Title: Redistribution of intracellular calcium and its effect on apoptosis in macrophages: Induction by oxidized LDL.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090501

Title: The conversion of rapid TCCD nongenomic signals to persistent inflammatory effects via select protein kinases in MCF10A cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20090401

Title: Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages.

Journal: Chemosphere 20090301

Title: L-type calcium channels govern calcium signaling in migrating newborn neurons in the postnatal olfactory bulb.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090225

Title: SV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosis.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090128

Title: D2 dopamine receptor activation facilitates endocannabinoid-mediated long-term synaptic depression of GABAergic synaptic transmission in midbrain dopamine neurons via cAMP-protein kinase A signaling.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081224

Title: Topography and affinity of calcium sensors of exo- and endocytosis in motor nerve terminals.

Journal: Bulletin of experimental biology and medicine 20081201

Title: Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells.

Journal: Molecular pharmacology 20080701

Title: Thrombin increases hyposmotic taurine efflux and accelerates ICI-swell and RVD in 3T3 fibroblasts by a src-dependent EGFR transactivation.

Journal: Pflugers Archiv : European journal of physiology 20080201

Title: Intracellular GSH levels rather than ROS levels are tightly related to AMA-induced HeLa cell death.

Journal: Chemico-biological interactions 20080110

Title: The membrane permeable calcium chelator BAPTA-AM directly blocks human ether a-go-go-related gene potassium channels stably expressed in HEK 293 cells.

Journal: Biochemical pharmacology 20071203

Title: Activity-dependent changes in temporal components of neurotransmission at the juvenile mouse calyx of Held synapse.

Journal: The Journal of physiology 20070601

Title: Evidences for calcium-dependent inactivation of calcium current at the frog motor nerve terminal.

Journal: Brain research bulletin 20060531

Title: Dysregulation of cellular calcium homeostasis in chemotherapy-evoked painful peripheral neuropathy.

Journal: Anesthesia and analgesia 20060501

Title: Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release.

Journal: Neuron 20051123

Title: Asynchronous GABA release generates long-lasting inhibition at a hippocampal interneuron-principal neuron synapse.

Journal: Nature neuroscience 20051001

Title: Hyposmolarity evokes norepinephrine efflux from synaptosomes by a depolarization- and Ca2+ -dependent exocytotic mechanism.

Journal: The European journal of neuroscience 20051001

Title: Dynamics of excitatory synaptic components in sustained firing at low rates.

Journal: Journal of neurophysiology 20050601

Title: Presynaptic Ca2+ requirements and developmental regulation of posttetanic potentiation at the calyx of Held.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050525

Title: Endolymphatic perfusion with EGTA-acetoxymethyl ester inhibits asphyxia- and furosemide-induced decrease in endocochlear potential in guinea pigs.

Journal: The Japanese journal of physiology 20050201

Title: [The mechanisms of short-term forms of synaptic plasticity].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20040801

Title: Effect of thrombopoietin alone and a combination of cytochalasin B and ethylene glycol bis(beta-aminoethyl ether) N,N'-tetraacetic acid-AM on the survival and function of autologous baboon platelets stored at 4 degrees C for as long as 5 days.

Journal: Transfusion 20040601

Title: Lysophosphatidylcholine inhibits endothelial cell migration by increasing intracellular calcium and activating calpain.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20030201

Title: Mechanism of the inhibitory effect of histamine on amygdaloid-kindled seizures in rats.

Journal: Epilepsia 20011201

Title: K(+)-induced HSP-72 expression is mediated via rapid Ca(2+) influx in renal epithelial cells.

Journal: American journal of physiology. Renal physiology 20010801

Title: A calcium microdomain near NMDA receptors: on switch for ERK-dependent synapse-to-nucleus communication.

Journal: Nature neuroscience 20010601

Title: Properties of synchronous and asynchronous release during pulse train depression in cultured hippocampal neurons.

Journal: Journal of neurophysiology 20010601

Title: Coupling of L-type calcium channels to neurotransmitter release at mouse motor nerve terminals.

Journal: Pflugers Archiv : European journal of physiology 20010301

Title: Intraterminal Ca(2+) and spontaneous transmitter release at the frog neuromuscular junction.

Journal: Journal of neurophysiology 20010101

Title: Li MJ, et al. Cholinergic and glutamatergic transmission at synapses between pedunculopotine tegmental nucleus axonal terminals and A7 catecholamine cell group noradrenergic neurons in the rat. Neuropharmacology. 2016 Nov;110(Pt A):237-50

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Tags:99590-86-0 Molecular Formula|99590-86-0 MDL|99590-86-0 SMILES|99590-86-0 Bis(acetoxymethyl) 3,12-bis(2-(acetoxymethoxy)-2-oxoethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioate