Title: Identification of glycan structure alterations on cell membrane proteins in desoxyepothilone B resistant leukemia cells.
Journal: Molecular & cellular proteomics : MCP20111101
Title: The characterization of microtubule-stabilizing drugs as possible therapeutic agents for Alzheimer's disease and related tauopathies.
Journal: Pharmacological research20110401
Title: Synthesis of (Z)-trisubstituted olefins by decarboxylative grob-type fragmentations: epothilone D, discodermolide, and peloruside A.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20100111
Title: Simultaneous determination of epothilone D and its hydrolytic metabolite in human plasma by high performance liquid chromatography-tandem mass spectrometry for pharmacokinetic studies.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20091101
Title: Determination of a novel epothilone D analog (AV-EPO-106) in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry.
Journal: Biomedical chromatography : BMC20090301
Title: Decarboxylative Grob-type fragmentations in the synthesis of trisubstituted Z olefins: application to peloruside A, discodermolide, and epothilone D.
Journal: Angewandte Chemie (International ed. in English)20090101
Title: Total synthesis of epothilones B and D: stannane equivalents for beta-keto ester dianions.
Journal: The Journal of organic chemistry20081219
Title: Epothilones and new analogues of the microtubule modulators in taxane-resistant disease.
Journal: Expert opinion on investigational drugs20080401
Title: Preclinical investigations with epothilones in breast cancer models.
Journal: Seminars in oncology20080401
Title: Clinical studies with epothilones for the treatment of metastatic breast cancer.
Journal: Seminars in oncology20080401
Title: Phase II study of KOS-862 in patients with metastatic androgen independent prostate cancer previously treated with docetaxel.
Journal: Investigational new drugs20071201
Title: Epothilone D, a microtubule-stabilizing compound, inhibits neointimal hyperplasia after rat carotid artery injury by cell cycle arrest via regulation of G1-checkpoint proteins.
Journal: Vascular pharmacology20071001
Title: Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kappaB/IkappaB kinase signal pathway.
Journal: Molecular cancer therapeutics20071001
Title: Novel tubulin-targeting agents: anticancer activity and pharmacologic profile of epothilones and related analogues.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology20070701
Title: Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia.
Journal: Journal of the National Cancer Institute20061004
Title: Determination of desoxyepothilone B in nude mice plasma by liquid-liquid extraction and reversed-phase high-performance liquid chromatography.
Journal: Journal of pharmaceutical and biomedical analysis20060918
Title: Heterologous production of epothilone C and D in Escherichia coli.
Journal: Biochemistry20060131
Title: Current state of the art of new tubulin inhibitors in the clinic.
Journal: Current clinical pharmacology20060101
Title: Total synthesis of 12,13-desoxyepothilone B (Epothilone D).
Journal: Bioorganic chemistry20050401
Title: Total syntheses of epothilones B and d.
Journal: The Journal of organic chemistry20041224
Title: Kinetics and mechanism of degradation of epothilone-D: an experimental anticancer agent.
Journal: Journal of pharmaceutical sciences20041201
Title: A comparison of signaling activities induced by Taxol and desoxyepothilone B.
Journal: Journal of chemotherapy (Florence, Italy)20041201
Title: Crystal structures of epothilone D-bound, epothilone B-bound, and substrate-free forms of cytochrome P450epoK.
Journal: The Journal of biological chemistry20031107
Title: Creating polyketide diversity through genetic engineering.
Journal: Frontiers in bioscience : a journal and virtual library20030101
Title: Probing the SAR of dEpoB via chemical synthesis: a total synthesis evaluation of C26-(1,3-dioxolanyl)-12,13-desoxyepothilone B.
Journal: The Journal of organic chemistry20021101
Title: A new cytotoxic epothilone from modified polyketide synthases heterologously expressed in Myxococcus xanthus.
Journal: Journal of natural products20020701
Title: Optimizing the heterologous production of epothilone D in Myxococcus xanthus.
Journal: Biotechnology and bioengineering20020505
Title: Large-scale isolation and crystallization of epothilone D from Myxococcus xanthus cultures.
Journal: Journal of natural products20020401
Title: Total synthesis of epothilones B and D.
Journal: Organic letters20010712
Title: New natural epothilones from Sorangium cellulosum, strains So ce90/B2 and So ce90/D13: isolation, structure elucidation, and SAR studies.
Journal: Journal of natural products20010701
Title: Total synthesis of epothilone B, epothilone D, and cis- and trans-9,10-dehydroepothilone D.
Journal: Journal of the American Chemical Society20010613
Title: Catalytic antibody route to the naturally occurring epothilones: total synthesis of epothilones A-F.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20010417
Title: Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma. Invest New Drugs. 2012 Dec;30(6):2294-302.
Title: Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. J Neurosci. 2010 Oct 13;30(41):13861-6.
