Home Amines 23325-78-2
23325-78-2,MFCD00167148
Catalog No.:AA002MS0

23325-78-2 | 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-, hydrate (1:1), (6R,7R)-

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1g
98
in stock  
$150.00   $105.00
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5g
98%
in stock  
$561.00   $393.00
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25g
98%
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$1,700.00   $1,190.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002MS0
Chemical Name:
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-, hydrate (1:1), (6R,7R)-
CAS Number:
23325-78-2
Molecular Formula:
C16H19N3O5S
Molecular Weight:
365.4042
MDL Number:
MFCD00167148
SMILES:
N[C@H](c1ccccc1)C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)C.O
Properties
Computed Properties
 
Complexity:
600  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
4  

Literature

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Journal: The Pediatric infectious disease journal 20121101

Title: Crystal structures of penicillin-binding protein 3 (PBP3) from methicillin-resistant Staphylococcus aureus in the apo and cefotaxime-bound forms.

Journal: Journal of molecular biology 20121026

Title: Removal of cefalexin using yeast surface-imprinted polymer prepared by atom transfer radical polymerization.

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Title: Prophylactic antibiotics for simple hand lacerations: time for a clinical trial?

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Title: Identification of priority pharmaceuticals in the water environment of China.

Journal: Chemosphere 20120901

Title: Multifocal cutaneous histiocytic sarcoma in a young dog and review of histiocytic cell immunophenotyping.

Journal: Veterinary clinical pathology 20120901

Title: Biodegradability enhancement of wastewater containing cefalexin by means of the electro-Fenton oxidation process.

Journal: Journal of hazardous materials 20120815

Title: Distribution, fate and risk assessment of antibiotics in sewage treatment plants in Hong Kong, South China.

Journal: Environment international 20120701

Title: Development of an ultrasonic slurry sampling method for the determination of Cu and Mn in antibiotic tablets by electrothermal atomic absorption spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20120701

Title: Susceptibility of coagulase-negative staphylococci to a kanamycin and cefalexin combination.

Journal: Journal of dairy science 20120601

Title: Characterization of biocompatible NiCo2O4 nanoparticles for applications in hyperthermia and drug delivery.

Journal: Nanomedicine : nanotechnology, biology, and medicine 20120501

Title: Construction, identification and application of HeLa cells stably transfected with human PEPT1 and PEPT2.

Journal: Peptides 20120401

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Journal: Minerva pediatrica 20120401

Title: The effect of staggered administration of zinc sulfate on the pharmacokinetics of oral cephalexin.

Journal: British journal of clinical pharmacology 20120301

Title: Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.

Journal: The Journal of pharmacology and experimental therapeutics 20120201

Title: In vitro release kinetics and physical, chemical and mechanical characterization of a POVIAC®/CaCO3/HAP-200 composite.

Journal: Journal of materials science. Materials in medicine 20120201

Title: Batch reactor performance for the enzymatic synthesis of cephalexin: influence of catalyst enzyme loading and particle size.

Journal: New biotechnology 20120115

Title: Pyoderma gangrenosum following patellar tendon repair: a case report and review of the literature.

Journal: American journal of orthopedics (Belle Mead, N.J.) 20120101

Title: Man with rash and nausea. Acute generalized exanthematous pustulosis after cephalexin use.

Journal: Annals of emergency medicine 20111201

Title: Subdiffraction-limit study of Kaede diffusion and spatial distribution in live Escherichia coli.

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Title: [Antibiotic resistance of bacteria to 6 antibiotics in secondary effluents of municipal wastewater treatment plants].

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Title: Characterization of cephalexin loaded nonionic microemulsions.

Journal: Journal of colloid and interface science 20110901

Title: Selection of CMY-2 producing Escherichia coli in the faecal flora of dogs treated with cephalexin.

Journal: Veterinary microbiology 20110805

Title: Pharmacokinetics and bioavailability of a long-acting formulation of cephalexin after intramuscular administration to cats.

Journal: Research in veterinary science 20110801

Title: Comparative pharmacokinetics of intravenous cephalexin in pregnant, lactating, and nonpregnant, nonlactating goats.

Journal: Journal of veterinary pharmacology and therapeutics 20110801

Title: Purification development and characterization of the zinc-dependent metallo-β-lactamase from Bacillus anthracis.

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Title: [Spectroscopy study on the selectively distinguishing cefalexin with the molecular imprinted polymer].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20110701

Title: Anaerobic stabilization and conversion of transformed intermediates of antibiotic pharmaceutical effluent in a fluidized bed reactor.

Journal: Journal of environmental science & engineering 20110701

Title: Does laboratory antibiotic susceptibility reporting influence primary care prescribing in urinary tract infection and other infections?

Journal: The Journal of antimicrobial chemotherapy 20110601

Title: Pharmacokinetics of a single oral administration of cefalexin in mares and foals.

Journal: The Veterinary record 20110423

Title: Randomized controlled trial of cephalexin versus clindamycin for uncomplicated pediatric skin infections.

Journal: Pediatrics 20110301

Title: Modulation in concentrative nucleoside transporters-mediated intestinal absorption of mizoribine, an immunosuppressive agent, in lipopolysaccharide-treated rats.

Journal: Die Pharmazie 20110301

Title: Removal of cephalexin from aqueous solutions by original and Cu(II)/Fe(III) impregnated activated carbons developed from lotus stalks Kinetics and equilibrium studies.

Journal: Journal of hazardous materials 20110130

Title: Kill rate of mastitis pathogens by a combination of cefalexin and kanamycin.

Journal: Journal of applied microbiology 20110101

Title: Effects of sodium bicarbonate and ammonium chloride pre-treatments on PEPT2 (SLC15A2) mediated renal clearance of cephalexin in healthy subjects.

Journal: Drug metabolism and pharmacokinetics 20110101

Title: Management of suppurative cervical lymphadenitis in a healthy 24-year-old man.

Journal: The Journal of the American Osteopathic Association 20110101

Title: [Pulmonary hydatic cyst--a case report].

Journal: Pneumologia (Bucharest, Romania) 20110101

Title: Analysis of 6 cases of drug-induced pemphigus.

Journal: European journal of dermatology : EJD 20110101

Title: Investigation of the antibacterial activity of pioglitazone.

Journal: Drug design, development and therapy 20110101

Title: Improved specific productivity in cephalexin synthesis by immobilized PGA in silica magnetic micro-particles.

Journal: Biotechnology and bioengineering 20101201

Title: Adherence to perioperative antibiotic prophylaxis among orthopedic trauma patients.

Journal: Canadian journal of surgery. Journal canadien de chirurgie 20101201

Title: Pharmacokinetics, protein binding, and tissue distribution of orally administered cefpodoxime proxetil and cephalexin in dogs.

Journal: American journal of veterinary research 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Management of osteonecrosis of the jaws in patients with history of bisphosphonates therapy.

Journal: The Journal of craniofacial surgery 20101101

Title: Cervical trophic syndrome.

Journal: Journal of the American Academy of Dermatology 20101001

Title: Empiric outpatient therapy with trimethoprim-sulfamethoxazole, cephalexin, or clindamycin for cellulitis.

Journal: The American journal of medicine 20101001

Title: [A simple disk diffusion test to identify beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae--application of cephalexin, cefsulodin and cefaclor disks].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20101001

Title: Effect of cationic micelles on the decomposition of alpha-aminophenyl cephalosporins.

Journal: Colloids and surfaces. B, Biointerfaces 20100901

Title: What is your diagnosis? Pneumopericardium.

Journal: Journal of the American Veterinary Medical Association 20100815

Title: In vivo effects of adjunctive tetracycline treatment on refractory corneal ulcers in dogs.

Journal: Journal of the American Veterinary Medical Association 20100815

Title: Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.

Journal: The Journal of pharmacology and experimental therapeutics 20100801

Title: Validation of the betaeta-s.t.a.r. 1 + 1 for rapid screening of residues of beta-lactam antibiotics in milk.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100801

Title: The role of antibiotics in reduction mammaplasty.

Journal: Annals of plastic surgery 20100801

Title: Transformation of beta-lactam antibacterial agents during aqueous ozonation: reaction pathways and quantitative bioassay of biologically-active oxidation products.

Journal: Environmental science & technology 20100801

Title: Cutaneous leishmaniasis in a child treated with oral fluconazole.

Journal: The Australasian journal of dermatology 20100801

Title: Painful rash on face.

Journal: The Journal of family practice 20100801

Title: A painful rash.

Journal: The Journal of emergency medicine 20100601

Title: Pharmacokinetic interaction between JBP485 and cephalexin in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100601

Title: Cephalexin microspheres for dairy mastitis: effect of preparation method and surfactant type on physicochemical properties of the microspheres.

Journal: AAPS PharmSciTech 20100601

Title: Effects of lithium carbonate on carboplatin-induced thrombocytopenia in dogs.

Journal: American journal of veterinary research 20100501

Title: Bronchospasms after infusion of a cephalosporin in anesthetized patients: what is the culprit?

Journal: Journal of the Chinese Medical Association : JCMA 20100401

Title: Prophylactic antibiotic administration induced bronchospasm as increased airway pressure during general anesthesia.

Journal: Journal of the Chinese Medical Association : JCMA 20100201

Title: Design and evaluation of gastroretentive mucoadhesive cephalexin tablets.

Journal: Pharmaceutical development and technology 20100101

Title: Determination of the crystallinity of cephalexin in pharmaceutical formulations by chemometrical near-infrared spectroscopy.

Journal: Drug development and industrial pharmacy 20100101

Title: Effects of Acanthopanax senticosus HARMS extract on drug transport in human intestinal cell line Caco-2.

Journal: Journal of natural medicines 20100101

Title: Measuring the bending stiffness of bacterial cells using an optical trap.

Journal: Journal of visualized experiments : JoVE 20100101

Title: A noninferiority clinical trial comparing fluconazole and ketoconazole in combination with cephalexin for the treatment of dogs with Malassezia dermatitis.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20100101

Title: Keloid formation occurring in the distribution of a congenital vascular malformation.

Journal: Skinmed 20100101

Title: In vitro studies as supporting evidence on the efficacy of antimicrobials for mastitis treatment.

Journal: Journal of applied microbiology 20091201

Title: Evaluating the in vitro susceptibility of bovine mastitis pathogens to a combination of kanamycin and cefalexin: Recommendations for a disk diffusion test.

Journal: Journal of dairy science 20091201

Title: Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis.

Journal: The Journal of biological chemistry 20091127

Title: The effect of wellsolve, a novel solubilizing agent, on the intestinal barrier function and intestinal absorption of griseofulvin in rats.

Journal: Biological & pharmaceutical bulletin 20091101

Title: Molecularly imprinted solid-phase extraction of cephalexin from water-based matrices.

Journal: Journal of separation science 20091001

Title: Case of the month. Compartment syndrome.

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20091001

Title: Effect of loading rate and HRT on the removal of cephalosporin and their intermediates during the operation of a membrane bioreactor treating pharmaceutical wastewater.

Journal: Environmental technology 20090901

Title: Dermal drug levels of antibiotic (cephalexin) determined by electroporation and transcutaneous sampling (ETS) technique.

Journal: Journal of pharmaceutical sciences 20090801

Title: Bioavailability and pharmacokinetics of a novel cephalexin oral paste formulation in fed and fasted dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20090801

Title: Direct evidence for efficient transport and minimal metabolism of L-cephalexin by oligopeptide transporter 1 in budded baculovirus fraction.

Journal: Biological & pharmaceutical bulletin 20090801

Title: Synergistic interactions between cefalexin and kanamycin in Mueller-Hinton broth medium and in milk.

Journal: Journal of applied microbiology 20090701

Title: Expandase-like activity mediated cell-free conversion of ampicillin to cephalexin by Streptomyces sp. DRS I.

Journal: Biotechnology letters 20090701

Title: Influences of solution chemistry and polymeric natural organic matter on the removal of aquatic pharmaceutical residuals by nanofiltration.

Journal: Water research 20090701

Title: Empirical antimicrobial therapy of acute dentoalveolar abscess.

Journal: Vojnosanitetski pregled 20090701

Title: Cephalexin residue detection in milk and beef by ELISA and colloidal gold based one-step strip assay.

Journal: Journal of agricultural and food chemistry 20090610

Title: Cephalexin-loaded injectable macroporous calcium phosphate bone cement.

Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20090501

Title: Usefulness of antibiogram surveillance for methicillin-resistant Staphylococcus aureus in outpatient pediatric populations.

Journal: Diagnostic microbiology and infectious disease 20090501

Title: Treatment of Staphylococcus aureus colonization in atopic dermatitis decreases disease severity.

Journal: Pediatrics 20090501

Title: A new biocatalyst: Penicillin G acylase immobilized in sol-gel micro-particles with magnetic properties.

Journal: Biotechnology journal 20090501

Title: Synthesis of cephalexin in aqueous medium with carrier-bound and carrier-free penicillin acylase biocatalysts.

Journal: Applied biochemistry and biotechnology 20090401

Title: Mechanism and implication of cephalosporin penetration into oropharyngeal mucosa.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20090401

Title: Morphological features and signature gene response elicited by inactivation of FtsI in Mycobacterium tuberculosis.

Journal: The Journal of antimicrobial chemotherapy 20090301

Title: Development and validation of an immunochromatographic assay for rapid multi-residues detection of cephems in milk.

Journal: Analytica chimica acta 20090216

Title: Pharyngeal colonization by Kingella kingae in children with invasive disease.

Journal: The Pediatric infectious disease journal 20090201

Title: Interethnic differences of PEPT2 (SLC15A2) polymorphism distribution and associations with cephalexin pharmacokinetics in healthy Asian subjects.

Journal: European journal of clinical pharmacology 20090101

Title: Quantitative evaluation of PEPT1 contribution to oral absorption of cephalexin in rats.

Journal: Pharmaceutical research 20090101

Title: Community-acquired methicillin-resistant Staphylococcus aureus: not just a spider bite.

Journal: Family & community health 20090101

Title: Management of vagal nerve stimulator infections: do they need to be removed?

Journal: Journal of neurosurgery. Pediatrics 20090101

Title: Preparation and characterization of cephalexin loaded PLGA microspheres.

Journal: Current drug delivery 20090101

Title: Antibiotic selection for purulent skin and soft-tissue infections in ambulatory care: a decision-analytic approach.

Journal: Academic pediatrics 20090101

Title: Rhodococcus equi infection in a surgical wound.

Journal: Clinical laboratory science : journal of the American Society for Medical Technology 20090101

Title: Comparative pharmacokinetics of an injectable cephalexin suspension in beef cattle.

Journal: Research in veterinary science 20081201

Title: Cephalexin remains preferred oral antibiotic therapy for uncomplicated cellulitis.

Journal: The American journal of medicine 20081101

Title: Non-random segregation of sister chromosomes in Escherichia coli.

Journal: Nature 20081030

Title: Xanthogranulomatous pyelonephritis infiltrating the liver.

Journal: Journal of pediatric surgery 20081001

Title: Teratogenicity of antibacterial agents.

Journal: Collegium antropologicum 20080901

Title: Efficacy and tolerability of once-daily cephalexin in canine superficial pyoderma: an open controlled study.

Journal: The Journal of small animal practice 20080801

Title: Selective solid-phase extraction of amoxicillin and cephalexin from urine samples using a molecularly imprinted polymer.

Journal: Journal of separation science 20080801

Title: hPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3.

Journal: Pflugers Archiv : European journal of physiology 20080601

Title: PDZK1 regulates two intestinal solute carriers (Slc15a1 and Slc22a5) in mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080601

Title: Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus.

Journal: The Journal of biological chemistry 20080516

Title: A retrospective review of ampicillin-sulbactam and amoxicillin + clavulanate vs cefazolin/cephalexin and erythromycin in the setting of preterm premature rupture of membranes: maternal and neonatal outcomes.

Journal: American journal of obstetrics and gynecology 20080501

Title: Prospective evaluation of the management of moderate to severe cellulitis with parenteral antibiotics at a paediatric day treatment centre.

Journal: Journal of paediatrics and child health 20080401

Title: Beta-haemolytic group A streptococci emm75 carrying altered pyrogenic exotoxin A linked to scarlet fever in adults.

Journal: The Journal of infection 20080401

Title: A survey of obstetricians' practice of using prophylactic antibiotics in vaginal deliveries and caesarean sections.

Journal: Journal of the Indian Medical Association 20080301

Title: Staphylococcus aureus bacteremia complicating herpes simplex virus type 1 stomatitis: case report and review of the literature.

Journal: Journal of periodontology 20080201

Title: Determination of faropenem in human plasma and urine by liquid chromatography-tandem mass spectrometry.

Journal: Biomedical chromatography : BMC 20080101

Title: Oral cephalexin for acne vulgaris: clinical experience with 93 patients.

Journal: Pediatric dermatology 20080101

Title: Cutaneous myiasis from Panama, South America: case report and review.

Journal: Journal of cutaneous medicine and surgery 20080101

Title: Pulmonary abscess of viral-bacterial etiology in a neonate.

Journal: European journal of pediatrics 20071201

Title: Management of cellulitis in a pediatric emergency department.

Journal: Pediatric emergency care 20071101

Title: In vitro activity of cefadroxil, cephalexin, cefatrizine and cefpirome in presence of essential and trace elements.

Journal: Pakistan journal of pharmaceutical sciences 20071001

Title: Long-term effect of leptin on H+-coupled peptide cotransporter 1 activity and expression in vivo: evidence in leptin-deficient mice.

Journal: The Journal of pharmacology and experimental therapeutics 20071001

Title: Cutaneous vasculitis following an intradermal tattoo.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20071001

Title: Case study and panel discussion.

Journal: Pharmacotherapy 20071001

Title: A comparative study of capillary zone electrophoresis and pH-potentiometry for determination of dissociation constants.

Journal: Journal of pharmaceutical and biomedical analysis 20070903

Title: Galbanic acid from Ferula szowitsiana enhanced the antibacterial activity of penicillin G and cephalexin against Staphylococcus aureus.

Journal: Biological & pharmaceutical bulletin 20070901

Title: Bilateral endogenous endophthalmitis after holmium laser lithotripsy.

Journal: Urology 20070901

Title: Clinical, histopathological and therapeutic considerations in a flock of sheep with facial staphylococcal-associated dermatitis.

Journal: Veterinary dermatology 20070801

Title: Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters.

Journal: Biochemical pharmacology 20070715

Title: Regulation of the oligopeptide transporter, PEPT-1, in DSS-induced rat colitis.

Journal: Digestive diseases and sciences 20070701

Title: Botryomycosis presenting as pruritic papules in a human immunodeficiency virus-positive patient.

Journal: Cutis 20070701

Title: Symptomatic relapse of group A beta-hemolytic streptococcal tonsillopharyngitis in children.

Journal: Clinical pediatrics 20070501

Title: Metoclopramide modifies oral cephalexin pharmacokinetics in dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20070401

Title: Functional expression of stereoselective metabolism of cephalexin by exogenous transfection of oligopeptide transporter PEPT1.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301

Title: Safe use of selected cephalosporins in penicillin-allergic patients: a meta-analysis.

Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20070301

Title: Effects of capsaicin on intestinal cephalexin absorption in rats.

Journal: Biological & pharmaceutical bulletin 20070301

Title: Evidence that focal adhesion complexes power bacterial gliding motility.

Journal: Science (New York, N.Y.) 20070209

Title: Success of short-course parenteral antibiotic therapy for acute osteomyelitis of childhood.

Journal: Clinical pediatrics 20070101

Title: Real-time TaqMan PCR for rapid detection and typing of genes encoding CTX-M extended-spectrum beta-lactamases.

Journal: Journal of medical microbiology 20070101

Title: Simultaneous determination of beta-lactamic antibiotics by a new high-performance low-pressure chromatographic system using a multisyringe burette coupled to a monolithic column (MSC).

Journal: Analytical and bioanalytical chemistry 20070101

Title: Chronopharmacological study of cephalexin in dogs.

Journal: Chronobiology international 20070101

Title: Pregnancy complications and birth outcomes of pregnant women with urinary tract infections and related drug treatments.

Journal: Scandinavian journal of infectious diseases 20070101

Title: Cephalexin inhibits N-formylated peptide transport and intestinal hyperpermeability in Caco2 cells.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101

Title: Pyoderma caused by Pseudomonas aeruginosa infection in dogs: 20 cases.

Journal: Veterinary dermatology 20061201

Title: Topical retapamulin ointment (1%, wt/wt) twice daily for 5 days versus oral cephalexin twice daily for 10 days in the treatment of secondarily infected dermatitis: results of a randomized controlled trial.

Journal: Journal of the American Academy of Dermatology 20061201

Title: Pustule-studded plaques after abrasion injury.

Journal: Archives of dermatology 20061201

Title: The additive effects of hepatitis C infection and end-stage renal disease in porphyria cutanea tarda.

Journal: Cutis 20061201

Title: Cefdinir vs. cephalexin for mild to moderate uncomplicated skin and skin structure infections in adolescents and adults.

Journal: Current medical research and opinion 20061201

Title: PepT1 mediates colon damage by transporting fMLP in rats with bowel resection.

Journal: The Journal of surgical research 20061101

Title: Abnormal expression of the peptide transporter PepT1 in the colon of massive bowel resection rat: a potential route for colonic mucosa damage by transport of fMLP.

Journal: Digestive diseases and sciences 20061101

Title: Successful treatment of recalcitrant necrotizing eosinophilic folliculitis using indomethacin and cephalexin.

Journal: The Australasian journal of dermatology 20061101

Title: Delirium in an adolescent patient during treatment with cephalexin.

Journal: The Journal of adolescent health : official publication of the Society for Adolescent Medicine 20061101

Title: Interference of Mycobacterium tuberculosis cell division by Rv2719c, a cell wall hydrolase.

Journal: Molecular microbiology 20061001

Title: Mucosal permeability of water-soluble drugs in the equine jejunum: a preliminary investigation.

Journal: Journal of veterinary pharmacology and therapeutics 20061001

Title: An outpatient medical treatment protocol for peritonsillar abscess.

Journal: Ear, nose, & throat journal 20061001

Title: A case of interface perianal dermatitis in a dog: is this an unusual manifestation of lupus erythematosus?

Journal: Veterinary pathology 20060901

Title: Morphological changes and proteome response of Corynebacterium glutamicum to a partial depletion of FtsI.

Journal: Microbiology (Reading, England) 20060801

Title: Controlled release of cephalexin through gellan gum beads: effect of formulation parameters on entrapment efficiency, size, and drug release.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060701

Title: Acute otitis media and mastoiditis following cochlear implantation.

Journal: International journal of pediatric otorhinolaryngology 20060501

Title: Transfer of probenecid and cephalexin into breast milk.

Journal: The Annals of pharmacotherapy 20060501

Title: Effects of doxycycline, amoxicillin, cephalexin, and enrofloxacin on hemostasis in healthy dogs.

Journal: American journal of veterinary research 20060401

Title: Community-acquired methicillin-resistant Staphylococcus aureus skin infection presenting as a periumbilical folliculitis.

Journal: Cutis 20060401

Title: Liquid chromatographic method for the simultaneous determination of cefalexin and trimethoprim in dog plasma and application to the pharmacokinetic studies of a coformulated preparation.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060307

Title: Expression and purification of penicillin G acylase enzymes from four different micro-organisms, and a comparative evaluation of their synthesis/hydrolysis ratios for cephalexin.

Journal: Protein expression and purification 20060301

Title: High-level production and covalent immobilization of Providencia rettgeri penicillin G acylase (PAC) from recombinant Pichia pastoris for the development of a novel and stable biocatalyst of industrial applicability.

Journal: Biotechnology and bioengineering 20060205

Title: Variability in renal clearance of substrates for renal transporters in chinese subjects.

Journal: Journal of clinical pharmacology 20060201

Title: Isolated obturator externus muscle abscess presenting as hip pain.

Journal: The Journal of emergency medicine 20060201

Title: Effects of progesterone and norethisterone on cephalexin transport and peptide transporter PEPT1 expression in human intestinal cell line Caco-2.

Journal: Biological & pharmaceutical bulletin 20060101

Title: Retapamulin ointment twice daily for 5 days vs oral cephalexin twice daily for 10 days for empiric treatment of secondarily infected traumatic lesions of the skin.

Journal: Skinmed 20060101

Title: Urinary bactericidal activity of oral antibiotics against common urinary tract pathogens in an ex vivo model.

Journal: Chemotherapy 20060101

Title: Fatal cephalosporin-induced acute hypersensitivity myocarditis.

Journal: Pediatric cardiology 20060101

Title: Outpatient treatment with corticosteroids and antibiotics for acalculous cholecystitis in chronic granulomatous disease.

Journal: Acta paediatrica (Oslo, Norway : 1992) 20051101

Title: Pharmacokinetics of two once-daily parenteral cephalexin formulations in dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20051001

Title: Pharmacokinetics and tissue fluid distribution of cephalexin in the horse after oral and i.v. administration.

Journal: Journal of veterinary pharmacology and therapeutics 20051001

Title: Routine use of antimicrobials by pregnant Indian women does not improve birth outcome: a randomized controlled trial.

Journal: Journal of health, population, and nutrition 20050901

Title: Rapid elimination of cefaclor from the cerebrospinal fluid is mediated by a benzylpenicillin-sensitive mechanism distinct from organic anion transporter 3.

Journal: The Journal of pharmacology and experimental therapeutics 20050801

Title: A prospective study of antibiotic efficacy in preventing infection in reduction mammaplasty.

Journal: Plastic and reconstructive surgery 20050701

Title: Comparison of the clinical efficacy of oral terbinafine and ketoconazole combined with cephalexin in the treatment of Malassezia dermatitis in dogs--a pilot study.

Journal: Veterinary dermatology 20050601

Title: Purification and characterization of inducible cephalexin synthesizing enzyme in Gluconobacter oxydans.

Journal: Bioscience, biotechnology, and biochemistry 20050301

Title: Multicentre audit of the treatment of uncomplicated urinary tract infection in South Thames.

Journal: International journal of STD & AIDS 20050101

Title: Characterization of rPEPT2-mediated Gly-Sar transport parameters in the rat kidney proximal tubule cell line SKPT-0193 cl.2 cultured in basic growth media.

Journal: Molecular pharmaceutics 20050101

Title: New media for the semiselective isolation and enumeration of Xanthomonas campestris pv. mangiferaeindicae, the causal agent of mango bacterial black spot.

Journal: Journal of applied microbiology 20050101

Title: Antibiotics in septoplasty: is it necessary?

Journal: Brazilian journal of otorhinolaryngology 20050101

Title: A randomized crossover study investigating the influence of ranitidine or omeprazole on the pharmacokinetics of cephalexin monohydrate.

Journal: Journal of clinical pharmacology 20041201

Title: A prospective study of the clinical findings, treatment and histopathology of 44 cases of pyotraumatic dermatitis.

Journal: Veterinary dermatology 20041201

Title: Molecularly imprinted solid phase extraction-pulsed elution-mass spectrometry for determination of cephalexin and alpha-aminocephalosporin antibiotics in human serum.

Journal: Journal of pharmaceutical and biomedical analysis 20041115

Title: Cephalexin-induced cholestatic hepatitis.

Journal: Journal of clinical gastroenterology 20041001

Title: Dissolution of infection-induced struvite bladder stones by using a noncalculolytic diet and antibiotic therapy.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20041001

Title: Polarographic behavior of cephalexin and its determination in pharmaceuticals and human serum.

Journal: Journal of pharmaceutical and biomedical analysis 20040903

Title: Synchronous replication initiation of the two Vibrio cholerae chromosomes.

Journal: Current biology : CB 20040713

Title: Calcium sulphate-based cements containing cephalexin.

Journal: Biomaterials 20040601

Title: Cephalexin-induced acute tubular necrosis.

Journal: Pharmacotherapy 20040601

Title: Blistering distal dactylitis: a case series in children under nine months of age.

Journal: The Journal of emergency medicine 20040501

Title: Evaluation of the effect of cephalexin and enrofloxacin on clinical laboratory measurements of urine glucose in dogs.

Journal: Journal of the American Veterinary Medical Association 20040501

Title: Penicillin derivatives induce chemical structure-dependent root development, and application for plant transformation.

Journal: Plant cell reports 20040401

Title: Effects of progesterone and norethisterone on cephalexin uptake in the human intestinal cell line Caco-2.

Journal: Biological & pharmaceutical bulletin 20040401

Title: Organometallic complexes with biological molecules. XVIII. Alkyltin(IV) cephalexinate complexes: synthesis, solid state and solution phase investigations.

Journal: Journal of inorganic biochemistry 20040301

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Title: Penicillin acylase-catalyzed synthesis of beta-lactam antibiotics in highly condensed aqueous systems: beneficial impact of kinetic substrate supersaturation.

Journal: Biotechnology and bioengineering 20040205

Title: Evaluation of magnetic polymer micro-beads as carriers of immobilised biocatalysts for selective and stereoselective transformations.

Journal: Biotechnology letters 20040201

Title: Binding of transition metal ions [cobalt, copper, nickel and zinc] with furanyl-, thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins as potent antibacterial agents.

Journal: Journal of enzyme inhibition and medicinal chemistry 20040201

Title: Antifungal cobalt(II), copper(II), nickel(II) and zinc(II) complexes of furanyl-,thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins.

Journal: Journal of enzyme inhibition and medicinal chemistry 20040201

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Title: Low risk of infection in selected human bites treated without antibiotics.

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Title: Bullous pemphigoid in a patient with psoriasis and possible drug reaction: a case report.

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Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20040101

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Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101

Title: The influence of experimental administration of ethanol and cephalexin on stomach mucous barrier of rat.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101

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Journal: American family physician 20031201

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Journal: The New England journal of medicine 20031023

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Journal: Journal of dairy science 20031001

Title: Herpes simplex virus prophylaxis with famciclovir in patients undergoing aesthetic facial CO2 laser resurfacing.

Journal: Cutis 20031001

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Journal: Transfusion 20030901

Title: Hydroxypropyl methylcellulose based cephalexin extended release tablets: influence of tablet formulation, hardness and storage on in vitro release kinetics.

Journal: Chemical & pharmaceutical bulletin 20030801

Title: Combination effects of cephalexin and gentamicin on Edwardsiella tarda and Streptococcus iniae.

Journal: International journal of antimicrobial agents 20030701

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Journal: Allergy 20030601

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Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030601

Title: [Impact of non-target gene mutations and reduced permeability of outer membrane on quinolone resistance and multiple antibiotic resistance in Escherichia coli].

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Journal: World journal of gastroenterology 20030415

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Journal: FEMS microbiology letters 20030214

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Journal: The Canadian journal of urology 20030201

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Journal: Veterinary journal (London, England : 1997) 20030101

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Journal: Advances in biochemical engineering/biotechnology 20030101

Title: Effects of an ethyl lactate shampoo in conjunction with a systemic antibiotic in the treatment of canine superficial bacterial pyoderma in an open-label, nonplacebo-controlled study.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20030101

Title: [Effect of ozone on antibiotic sensitivity of microorganisms].

Journal: Stomatologiia 20030101

Title: Conjugation of penicillin acylase with the reactive copolymer of N-isopropylacrylamide: a step toward a thermosensitive industrial biocatalyst.

Journal: Biotechnology progress 20030101

Title: Efficacy of cephalexin two vs. three times daily vs. cefadroxil once daily for streptococcal tonsillopharyngitis.

Journal: Clinical pediatrics 20030101

Title: Neonatal suppurative parotitis: a case report.

Journal: Clinical pediatrics 20030101

Title: Arachnid envenomation from the brown recluse spider.

Journal: Clinical pediatrics 20030101

Title: Comparison of micellar electrokinetic chromatography, liquid chromatography, and microbiologic assay for analysis of cephalexin in oral suspensions.

Journal: Journal of AOAC International 20030101

Title: Enzyme distribution derived from macroscopic particle behavior of an industrial immobilized penicillin-G acylase.

Journal: Biotechnology progress 20030101

Title: Histological changes of white rat kidney after experimental administration of ethanol and cephalexin.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20030101

Title: Orbital abscess following uncomplicated phacoemulsification cataract surgery.

Journal: Clinical & experimental ophthalmology 20021201

Title: Antibiotic-associated maculopapular reaction.

Journal: The Annals of pharmacotherapy 20021201

Title: Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2.

Journal: Bioscience, biotechnology, and biochemistry 20021201

Title: High-dose antibiotic therapy is superior to a 3-drug combination of prostanoids and lipid A derivative in protecting irradiated canines.

Journal: Journal of radiation research 20021201

Title: Modelling of the enzymatic kinetically controlled synthesis of cephalexin: influence of diffusion limitation.

Journal: Biotechnology and bioengineering 20021105

Title: Influence of a new prophylactic antibiotic therapy on the incidence of liver abscesses after chemoembolization treatment of liver tumors.

Journal: Journal of vascular and interventional radiology : JVIR 20021101

Title: In vitro and in situ evidence for the contribution of Labrasol and Gelucire 44/14 on transport of cephalexin and cefoperazone by rat intestine.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20021101

Title: Integrated reactor concepts for the enzymatic kinetic synthesis of cephalexin.

Journal: Biotechnology and bioengineering 20021020

Title: Selective antibiotic use to prevent postoperative wound infection after external dacryocystorhinostomy.

Journal: Ophthalmic plastic and reconstructive surgery 20020901

Title: Advantages of using non-isothermal bioreactors for the enzymatic synthesis of antibiotics: the penicillin G acylase as enzyme model.

Journal: Biotechnology and bioengineering 20020805

Title: A two-step, one-pot enzymatic synthesis of cephalexin from D-phenylglycine nitrile.

Journal: Biotechnology and bioengineering 20020805

Title: Prophylactic antibiotics in cirrhotics with upper gastrointestinal hemorrhage: a prospective, controlled trial.

Journal: Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20020801

Title: Comparison of several methods used for the determination of cephalosporins. Analysis of cephalexin in pharmaceutical samples.

Journal: Journal of pharmaceutical and biomedical analysis 20020701

Title: Update on prosthetic joints, dental treatment, and antibiotic prophylaxis.

Journal: Dentistry today 20020701

Title: Pharmacokinetics of cephalexin in the horse after intravenous and intramuscular administration of two formulations.

Journal: Veterinary journal (London, England : 1997) 20020701

Title: Generalized pustules in a healthy woman.

Journal: Journal of drugs in dermatology : JDD 20020701

Title: The effect of tablet formulation and hardness on in vitro release of cephalexin from Eudragit L100 based extended release tablets.

Journal: Biological & pharmaceutical bulletin 20020401

Title: Salmonella mastitis in a child.

Journal: Clinical pediatrics 20020401

Title: Emergence of new pathogens in CF: the devil we know or the devil we don't know?

Journal: The Journal of pediatrics 20020301

Title: Antibiotic prophylaxis in infants and young children with cystic fibrosis: a randomized controlled trial.

Journal: The Journal of pediatrics 20020301

Title: [Improvement of efficacy of the bacteriological diagnosis in whooping cough].

Journal: Klinicheskaia laboratornaia diagnostika 20020201

Title: [Studies on enzymatic synthesis of cephalexin by immobilized penicillin acylase by polyacrylonitrile fibres].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20020201

Title: Comparison of bidirectional cephalexin transport across MDCK and caco-2 cell monolayers: interactions with peptide transporters.

Journal: Pharmaceutical research 20020101

Title: [Pharmacokinetics of cephalexin from two oral formulations in dogs].

Journal: Berliner und Munchener tierarztliche Wochenschrift 20020101

Title: A comparison of the efficacy and safety of mupirocin cream and cephalexin in the treatment of secondarily infected eczema.

Journal: Clinical and experimental dermatology 20020101

Title: Determination of cephalexin in oral suspensions by micellar electrokinetic chromatography.

Journal: Journal of capillary electrophoresis and microchip technology 20020101

Title: Effect of cephalexin on the pharmacokinetics of metformin in healthy human volunteers.

Journal: Drug metabolism and drug interactions 20020101

Title: Enzyme reaction engineering: effect of methanol on the synthesis of antibiotics catalyzed by immobilized penicillin G acylase under isothermal and non-isothermal conditions.

Journal: Biotechnology progress 20020101

Title: Analgesic effect of meloxicam in canine acute dermatitis--a pilot study.

Journal: Acta veterinaria Scandinavica 20020101

Title: Histological changes in the pancreas of white rats after administering cephalexin and ethanol.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101

Title: Ultrastructural changes of pancreas of white rats after experimental administration of ethanol and cephalexin.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101

Title: Concentration-dependent preferences of absorptive and excretive transport cause atypical intestinal absorption of cyclic phenylalanylserine: small intestine acts as an interface between the body and ingested compounds.

Journal: Research communications in molecular pathology and pharmacology 20020101

Title: PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine.

Journal: The Journal of clinical investigation 20011115

Title: Consensus statement on management of antenatally detected hydronephrosis.

Journal: Indian pediatrics 20011101

Title: Introduction of recirculatory analysis into portal and systemic concentration difference method.

Journal: Biological & pharmaceutical bulletin 20011101

Title: CF and antistaphylococcal prophylaxis.

Journal: Thorax 20011001

Title: Outpatient management of low-velocity gunshot-induced fractures.

Journal: Orthopedics 20011001

Title: Equal allergenic potency of beta-lactam antibiotics produced by chemical or enzymatic manufacturing--mouse IgE test.

Journal: International archives of allergy and immunology 20011001

Title: Invasive group A streptococcus in two siblings: a case for antibiotic prophylaxis of close contacts.

Journal: Canada communicable disease report = Releve des maladies transmissibles au Canada 20010901

Title: Cephalexin tolerated despite delayed aminopenicillin reactions.

Journal: Allergy 20010801

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Journal: Archives of pediatrics & adolescent medicine 20010601

Title: Modeling of the enzymatic kinetic synthesis of cephalexin--influence of substrate concentration and temperature.

Journal: Biotechnology and bioengineering 20010505

Title: Bullous pemphigoid induced by cephalexin.

Journal: The Australasian journal of dermatology 20010501

Title: Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase.

Journal: Cellular and molecular life sciences : CMLS 20010501

Title: Factors associated with antibiotic resistance in coliform organisms from community urinary tract infection in Wales.

Journal: The Journal of antimicrobial chemotherapy 20010301

Title: Mutations in DnaA protein suppress the growth arrest of acidic phospholipid-deficient Escherichia coli cells.

Journal: The EMBO journal 20010301

Title: Antibiotic prophylaxis for full-face laser resurfacing: is it necessary?

Journal: Archives of dermatology 20010301

Title: Take a 2nd look at your first impression.

Journal: JEMS : a journal of emergency medical services 20010301

Title: Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein.

Journal: AAPS pharmSci 20010301

Title: Bioaugmentation and treatment of cephalexin drug-based pharmaceutical effluent in an upflow anaerobic fluidized bed system.

Journal: Bioresource technology 20010201

Title: Roles of Escherichia coli histone-like protein HU in DNA replication: HU-beta suppresses the thermosensitivity of dnaA46ts.

Journal: Biochimie 20010201

Title: Effects of ceramic component on cephalexin release from bioactive bone cement consisting of Bis-GMA/TEGDMA resin and bioactive glass ceramics.

Journal: Bio-medical materials and engineering 20010101

Title: Severe anaphylaxis after a chlorhexidine bath.

Journal: Journal of the American Academy of Dermatology 19990501

Title: Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells.

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Title: A large population-based follow-up study of trimethoprim-sulfamethoxazole, trimethoprim, and cephalexin for uncommon serious drug toxicity.

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Title: Cholestatic jaundice and hematuria due to hypersensitivity to cefaclor in a child.

Journal: Journal of toxicology. Clinical toxicology 19830301

Title: Ototoxicity associated with cephalexin in two patients with renal failure.

Journal: Lancet (London, England) 19821120

Title: Cephalosporin-induced cholestatic jaundice.

Journal: Lancet (London, England) 19820807

Title: Cefroxadine (CGP-9000), an orally active cephalosporin.

Journal: Antimicrobial agents and chemotherapy 19800701

Title: Cephalexin-related nephropathy.

Journal: JAMA 19751110

Title: Cephalexin nephrotoxicity. Reversible nonoliguric acute renal failure and hepatotoxicity associated with cephalexin therapy.

Journal: JAMA 19740715

Title: Relative nephrotoxicity of cephalosporin antibiotics in an animal model.

Journal: Canadian Medical Association journal 19720909

Title: Acute intravascular haemolysis associated with cephalexin therapy.

Journal: Postgraduate medical journal 19720301

Title: Cephalexin dosage in general practice assessed by double-blind trial.

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Tags:23325-78-2 Molecular Formula|23325-78-2 MDL|23325-78-2 SMILES|23325-78-2 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-, hydrate (1:1), (6R,7R)-