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2854-32-2,MFCD01317813
Catalog No.:AA002VL5

2854-32-2 | Ethanone, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)-

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5mg
≥98%
in stock  
$38.00   $26.00
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10mg
≥98%
in stock  
$69.00   $48.00
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50mg
98%
in stock  
$268.00   $188.00
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100mg
98%
in stock  
$427.00   $299.00
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250mg
98%
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$890.00   $623.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002VL5
Chemical Name:
Ethanone, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)-
CAS Number:
2854-32-2
Molecular Formula:
C23H23ClN2O4
Molecular Weight:
426.8927
MDL Number:
MFCD01317813
SMILES:
COc1ccc2c(c1)c(CC(=O)N1CCOCC1)c(n2C(=O)c1ccc(cc1)Cl)C
Properties
Computed Properties
 
Complexity:
618  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
3.8  

Literature

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: In vitro metabolism of indomethacin morpholinylamide (BML-190), an inverse agonist for the peripheral cannabinoid receptor (CB(2)) in rat liver microsomes.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100911

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: BML-111, a lipoxin receptor agonist, modulates the immune response and reduces the severity of collagen-induced arthritis.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080401

Title: Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors.

Journal: Calcified tissue international 20070101

Title: Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor.

Journal: British journal of pharmacology 20030601

Title: BML-190 and AM251 act as inverse agonists at the human cannabinoid CB2 receptor: signalling via cAMP and inositol phosphates.

Journal: FEBS letters 20030211

Title: Zhang, Qiang; Ma, Peng; Cole, Richard B.; Wang, Guangdi In vitro metabolism of indomethacin morpholinylamide (BML-190), an inverse agonist for the peripheral cannabinoid receptor (CB2) in rat liver microsomes. European Journal of Pharmaceutical Sciences (2010), 41(1), 163-172.

Title: Klegeris, Andis; Bissonnette, Christopher J.; McGeer, Patrick L. Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor. British Journal of Pharmacology (2003), 139(4), 775-786.

Title: New DC, Wong YH. BML-190 and AM251 act as inverse agonists at the human cannabinoid CB2 receptor: signalling via cAMP and inositol phosphates. FEBS Lett. 2003 Feb 11;536(1-3):157-60.

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SDS
Tags:2854-32-2 Molecular Formula|2854-32-2 MDL|2854-32-2 SMILES|2854-32-2 Ethanone, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)-