Home Other Building Blocks 29908-03-0
29908-03-0,MFCD00871208
Catalog No.:AA0035HX

29908-03-0 | S-Adenosyl-l-methionine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
in stock  
$124.00   $87.00
- +
25mg
98%
in stock  
$224.00   $157.00
- +
100mg
98%
in stock  
$593.00   $415.00
- +
250mg
98%
in stock  
$1,208.00   $846.00
- +
1g
98%
in stock  
$3,004.00   $2,103.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0035HX
Chemical Name:
S-Adenosyl-l-methionine
CAS Number:
29908-03-0
Molecular Formula:
C15H22N6O5S
Molecular Weight:
398.4374
MDL Number:
MFCD00871208
SMILES:
C[S+](C[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N)CC[C@@H](C(=O)[O-])N
Properties
Properties
 
BP:
78°C  
Form:
Solid  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
527  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  
XLogP3:
-2.8  

Downstream Synthesis Route
67-56-1    29908-03-0    1976-85-8   
CASUnavailable 
 
CASUnavailable 
 
CASUnavailable 

[1]Pichon-Santander,Clotilde;Santander,PatricioJ.;Scott,A.Ian[BioorganicandMedicinalChemistry,2006,vol.14,#11,p.3904-3922]

67-56-1    29908-03-0    1976-85-8   
CASUnavailable 
 
CASUnavailable 
 
CASUnavailable 

[1]Pichon-Santander,Clotilde;Santander,PatricioJ.;Scott,A.Ian[BioorganicandMedicinalChemistry,2006,vol.14,#11,p.3904-3922]

[1]Locationinpatent:bodytextLee,Jin-Hee;Bae,Brian;Kuemin,Michael;Circello,BenjaminT.;Metcalf,WilliamW.;Nair,SatishK.;VanDerDonk,WilfredA.[ProceedingsoftheNationalAcademyofSciencesoftheUnitedStatesofAmerica,2010,vol.107,#41,p.17557-17562]

CASUnavailable 
  29908-03-0   
CASUnavailable 

[1]Kudithipudi,Srikanth;Lungu,Cristiana;Rathert,Philipp;Happel,Nicole;Jeltsch,Albert[ChemistryandBiology,2014,vol.21,#2,p.226-237]

Literature

Title: Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice.

Journal: The Journal of nutritional biochemistry 20171001

Title: Biochemical Characterization and Structural Basis of Reactivity and Regioselectivity Differences between Burkholderia thailandensis and Burkholderia glumae 1,6-Didesmethyltoxoflavin N-Methyltransferase.

Journal: Biochemistry 20170801

Title: PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase.

Journal: The Journal of biological chemistry 20160624

Title: Vimentin-Mediated Steroidogenesis Induced by Phthalate Esters: Involvement of DNA Demethylation and Nuclear Factor κB.

Journal: PloS one 20160101

Title: Alternatively Spliced Methionine Synthase in SH-SY5Y Neuroblastoma Cells: Cobalamin and GSH Dependence and Inhibitory Effects of Neurotoxic Metals and Thimerosal.

Journal: Oxidative medicine and cellular longevity 20160101

Title: Identification of Small Molecule Inhibitors of Human As(III) S-Adenosylmethionine Methyltransferase (AS3MT).

Journal: Chemical research in toxicology 20151221

Title: The effect of a methyl-deficient diet on the global DNA methylation and the DNA methylation regulatory pathways.

Journal: Journal of applied toxicology : JAT 20151201

Title: A fragment-based approach to identifying S-adenosyl-l-methionine -competitive inhibitors of catechol O-methyl transferase (COMT).

Journal: Journal of medicinal chemistry 20140626

Title: Arsenic trioxide attenuates the invasion potential of human liver cancer cells through the demethylation-activated microRNA-491.

Journal: Toxicology letters 20140605

Title: Decreased glutathione and elevated hair mercury levels are associated with nutritional deficiency-based autism in Oman.

Journal: Experimental biology and medicine (Maywood, N.J.) 20140601

Title: The functions of crucial cysteine residues in the arsenite methylation catalyzed by recombinant human arsenic (III) methyltransferase.

Journal: PloS one 20140101

Title: The role of catechol-O-methyltransferase in catechol-enhanced erythroid differentiation of K562 cells.

Journal: Toxicology and applied pharmacology 20131215

Title: Alterations in hepatic metabolism of sulfur amino acids in non-obese type-2 diabetic Goto-Kakizaki rats.

Journal: Chemico-biological interactions 20130705

Title: Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function.

Journal: Nature 20130606

Title: Role of epigenetic and miR-22 and miR-29b alterations in the downregulation of Mat1a and Mthfr genes in early preneoplastic livers in rats induced by 2-acetylaminofluorene.

Journal: Molecular carcinogenesis 20130401

Title: Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease.

Journal: Hepatology (Baltimore, Md.) 20130201

Title: Rapid equilibrium kinetic analysis of arsenite methylation catalyzed by recombinant human arsenic (+3 oxidation state) methyltransferase (hAS3MT).

Journal: The Journal of biological chemistry 20121109

Title: Allosteric communication between the pyridoxal 5'-phosphate (PLP) and heme sites in the H2S generator human cystathionine β-synthase.

Journal: The Journal of biological chemistry 20121102

Title: Radical SAM enzymes in the biosynthesis of sugar-containing natural products.

Journal: Biochimica et biophysica acta 20121101

Title: Mechanistic studies of the radical SAM enzyme spore photoproduct lyase (SPL).

Journal: Biochimica et biophysica acta 20121101

Title: Radical AdoMet enzymes in complex metal cluster biosynthesis.

Journal: Biochimica et biophysica acta 20121101

Title: Biotin synthase: insights into radical-mediated carbon-sulfur bond formation.

Journal: Biochimica et biophysica acta 20121101

Title: Structural diversity in the AdoMet radical enzyme superfamily.

Journal: Biochimica et biophysica acta 20121101

Title: S-adenosylmethionine (SAMe) therapy in liver disease: a review of current evidence and clinical utility.

Journal: Journal of hepatology 20121101

Title: Identification and function of auxiliary iron-sulfur clusters in radical SAM enzymes.

Journal: Biochimica et biophysica acta 20121101

Title: Radical SAM enzymes involved in the biosynthesis of purine-based natural products.

Journal: Biochimica et biophysica acta 20121101

Title: High-energy compounds promote physiological processing of Alzheimer's amyloid-β precursor protein and boost cell survival in culture.

Journal: Journal of neurochemistry 20121101

Title: Methionine adenosyltransferase I/III deficiency: neurological manifestations and relevance of S-adenosylmethionine.

Journal: Molecular genetics and metabolism 20121101

Title: The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenic.

Journal: Toxicology and applied pharmacology 20121101

Title: Radical SAM enzymes in methylation and methylthiolation.

Journal: Metallomics : integrated biometal science 20121101

Title: A RubisCO-like protein links SAM metabolism with isoprenoid biosynthesis.

Journal: Nature chemical biology 20121101

Title: Structure analysis of geranyl pyrophosphate methyltransferase and the proposed reaction mechanism of SAM-dependent C-methylation.

Journal: Acta crystallographica. Section D, Biological crystallography 20121101

Title: Structural characterization of a modification subunit of a putative type I restriction enzyme from Vibrio vulnificus YJ016.

Journal: Acta crystallographica. Section D, Biological crystallography 20121101

Title: Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis.

Journal: Journal of the American Chemical Society 20121031

Title: The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis.

Journal: The Journal of biological chemistry 20121026

Title: Synthetic biotechnology to study and engineer ribosomal bottromycin biosynthesis.

Journal: Chemistry & biology 20121026

Title: S-adenosylmethionine-dependent protein methylation is required for expression of selenoprotein P and gluconeogenic enzymes in HepG2 human hepatocytes.

Journal: The Journal of biological chemistry 20121019

Title: Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis.

Journal: The Journal of biological chemistry 20121019

Title: Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20121001

Title: Methylation of arsenic by recombinant human wild-type arsenic (+3 oxidation state) methyltransferase and its methionine 287 threonine (M287T) polymorph: Role of glutathione.

Journal: Toxicology and applied pharmacology 20121001

Title: An ABC transporter complex containing S-adenosylmethionine (SAM)-induced ATP-binding protein is involved in antibiotics production and SAM signaling in Streptomyces coelicolor M145.

Journal: Biotechnology letters 20121001

Title: Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.

Journal: Molecular nutrition & food research 20121001

Title: The comprehensive effects of hyperlipidemia and hyperhomocysteinemia on pathogenesis of atherosclerosis and DNA hypomethylation in ApoE-/- mice.

Journal: Acta biochimica et biophysica Sinica 20121001

Title: Radical SAM-dependent carbon insertion into the nitrogenase M-cluster.

Journal: Science (New York, N.Y.) 20120928

Title: Betaine homocysteine methyltransferase is active in the mouse blastocyst and promotes inner cell mass development.

Journal: The Journal of biological chemistry 20120921

Title: Metaboloepigenetics: interrelationships between energy metabolism and epigenetic control of gene expression.

Journal: Journal of cellular physiology 20120901

Title: S-adenosyl methionine regulates ubiquitin-conjugating enzyme 9 protein expression and sumoylation in murine liver and human cancers.

Journal: Hepatology (Baltimore, Md.) 20120901

Title: S-adenosyl-L-methionine (SAMe) for smoking abstinence: a randomized clinical trial.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20120901

Title: Novel protective mechanisms for S-adenosyl-L-methionine against acetaminophen hepatotoxicity: improvement of key antioxidant enzymatic function.

Journal: Toxicology letters 20120803

Title: Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation.

Journal: The Journal of nutritional biochemistry 20120801

Title: Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway.

Journal: Journal of the American Chemical Society 20120801

Title: Structure of Aeropyrum pernix fibrillarin in complex with natively bound S-adenosyl-L-methionine at 1.7 Å resolution.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20120801

Title: Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in Danio rerio.

Journal: Toxicology and applied pharmacology 20120715

Title: S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice.

Journal: Neurobiology of aging 20120701

Title: Relationships among biomarkers of one-carbon metabolism.

Journal: Molecular biology reports 20120701

Title: Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA.

Journal: Journal of structural biology 20120701

Title: Nutritional B vitamin deficiency disrupts lipid metabolism causing accumulation of proatherogenic lipoproteins in the aorta adventitia of ApoE null mice.

Journal: Molecular nutrition & food research 20120701

Title: Supra-physiological folic acid concentrations induce aberrant DNA methylation in normal human cells in vitro.

Journal: Epigenetics 20120701

Title: Biomarkers of the one-carbon pathway in association with congenital diaphragmatic hernia.

Journal: Birth defects research. Part A, Clinical and molecular teratology 20120701

Title: Folates and S-adenosylmethionine for major depressive disorder.

Journal: Canadian journal of psychiatry. Revue canadienne de psychiatrie 20120701

Title: DNA extraction method with improved efficiency and specificity using DNA methyltransferase and 'click' chemistry.

Journal: Analytical biochemistry 20120615

Title: Conformational properties of nine purified cystathionine β-synthase mutants.

Journal: Biochemistry 20120612

Title: Resurgence of serine: an often neglected but indispensable amino Acid.

Journal: The Journal of biological chemistry 20120608

Title: A novel genome-based approach correlates TMPRSS3 overexpression in ovarian cancer with DNA hypomethylation.

Journal: Gynecologic oncology 20120601

Title: Mallory-Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells.

Journal: Experimental and molecular pathology 20120601

Title: The association between plasma homocysteine levels, methylation capacity and incident osteoporotic fractures.

Journal: Bone 20120601

Title: Methionine sulfoxide reductase contributes to meeting dietary methionine requirements.

Journal: Archives of biochemistry and biophysics 20120601

Title: Structure and folding of a rare, natural kink turn in RNA with an A*A pair at the 2b*2n position.

Journal: RNA (New York, N.Y.) 20120601

Title: Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?

Journal: Experimental eye research 20120601

Title: Significantly enhanced production of acarbose in fed-batch fermentation with the addition of S-adenosylmethionine.

Journal: Journal of microbiology and biotechnology 20120601

Title: Dietary supplement drug therapies for depression.

Journal: Journal of psychosocial nursing and mental health services 20120601

Title: Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder.

Journal: The Journal of clinical psychiatry 20120601

Title: Characterization of yatakemycin gene cluster revealing a radical S-adenosylmethionine dependent methyltransferase and highlighting spirocyclopropane biosynthesis.

Journal: Journal of the American Chemical Society 20120530

Title: A selenium-based click AdoMet analogue for versatile substrate labeling with wild-type protein methyltransferases.

Journal: Chembiochem : a European journal of chemical biology 20120529

Title: Conformational heterogeneity of the SAM-I riboswitch transcriptional ON state: a chaperone-like role for S-adenosyl methionine.

Journal: Journal of molecular biology 20120518

Title: Riboswitch structure in the ligand-free state.

Journal: Wiley interdisciplinary reviews. RNA 20120501

Title: Development of rationally designed DNA N6 adenine methyltransferase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20120501

Title: Early changes in the liver-soluble proteome from mice fed a nonalcoholic steatohepatitis inducing diet.

Journal: Proteomics 20120501

Title: Nutritional interventions to prevent and treat osteoarthritis. Part II: focus on micronutrients and supportive nutraceuticals.

Journal: PM & R : the journal of injury, function, and rehabilitation 20120501

Title: Radical-mediated enzymatic methylation: a tale of two SAMS.

Journal: Accounts of chemical research 20120417

Title: Structure of geranyl diphosphate C-methyltransferase from Streptomyces coelicolor and implications for the mechanism of isoprenoid modification.

Journal: Biochemistry 20120410

Title: Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine.

Journal: Journal of the American Chemical Society 20120404

Title: Changes in IL12A methylation pattern in livers from mice fed DDC.

Journal: Experimental and molecular pathology 20120401

Title: Post-translational stabilization of thiopurine S-methyltransferase by S-adenosyl-L-methionine reveals regulation of TPMT*1 and *3C allozymes.

Journal: Biochemical pharmacology 20120401

Title: [Comparative evaluation of clinical efficacy of drugs remaxol and ademetionine in patients with acute ethanol poisoning complicated by the toxic damage of the liver].

Journal: Georgian medical news 20120401

Title: Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid.

Journal: Clinical chemistry and laboratory medicine 20120324

Title: Fluorescence imaging of cellular metabolites with RNA.

Journal: Science (New York, N.Y.) 20120309

Title: S-adenosylmethionine treatment in methionine adenosyltransferase deficiency, a case report.

Journal: Molecular genetics and metabolism 20120301

Title: Enhanced co-production of S-adenosylmethionine and glutathione by an ATP-oriented amino acid addition strategy.

Journal: Bioresource technology 20120301

Title: High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus).

Journal: Acta crystallographica. Section D, Biological crystallography 20120301

Title: Catechol-O-methyltransferase in complex with substituted 3'-deoxyribose bisubstrate inhibitors.

Journal: Acta crystallographica. Section D, Biological crystallography 20120301

Title: Sulfamethazine suppresses epigenetic silencing in Arabidopsis by impairing folate synthesis.

Journal: The Plant cell 20120301

Title: The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A.

Journal: Nature chemical biology 20120226

Title: A combined model of hepatic polyamine and sulfur amino acid metabolism to analyze S-adenosyl methionine availability.

Journal: Amino acids 20120201

Title: Effects of S-adenosylmethionine augmentation of serotonin-reuptake inhibitor antidepressants on cognitive symptoms of major depressive disorder.

Journal: Journal of affective disorders 20120201

Title: The effect of SAMe and betaine on Hepa 1-6, C34 and E47 liver cell survival in vitro.

Journal: Experimental and molecular pathology 20120201

Title: Nutritional influences on epigenetics and age-related disease.

Journal: The Proceedings of the Nutrition Society 20120201

Title: Methylation of catechins and procyanidins by rat and human catechol-O-methyltransferase: metabolite profiling and molecular modeling studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120201

Title: Alcohol intake and folate antagonism via CYP2E1 and ALDH1: effects on oral carcinogenesis.

Journal: Medical hypotheses 20120201

Title: Two patients with hepatic mtDNA depletion syndromes and marked elevations of S-adenosylmethionine and methionine.

Journal: Molecular genetics and metabolism 20120201

Title: Effects of S-adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice.

Journal: Carcinogenesis 20120201

Title: Atomic-level insights into metabolite recognition and specificity of the SAM-II riboswitch.

Journal: RNA (New York, N.Y.) 20120201

Title: The role of S-adenosylmethionine in preventing oxaliplatin-induced liver toxicity: a retrospective analysis in metastatic colorectal cancer patients treated with bevacizumab plus oxaliplatin-based regimen.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20120101

Title: Dietary supplementation with S-adenosyl methionine delayed amyloid-β and tau pathology in 3xTg-AD mice.

Journal: Journal of Alzheimer's disease : JAD 20120101

Title: Design, synthesis and in vitro evaluation of novel bivalent S-adenosylmethionine analogues.

Journal: Bioorganic & medicinal chemistry letters 20120101

Title: SAMe and HuR in liver physiology: usefulness of stem cells in hepatic differentiation research.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo.

Journal: Molecular medicine (Cambridge, Mass.) 20120101

Title: DNA methyltransferases: mechanistic models derived from kinetic analysis.

Journal: Critical reviews in biochemistry and molecular biology 20120101

Title: S-adenosylmethionine does not reduce ischaemia-reperfusion injury to a marginal liver graft in an in vivo experiment.

Journal: Hepato-gastroenterology 20120101

Title: In vitro study of uptake and synthesis of creatine and its precursors by cerebellar granule cells and astrocytes suggests some hypotheses on the physiopathology of the inherited disorders of creatine metabolism.

Journal: BMC neuroscience 20120101

Title: Arsenic induces functional re-expression of estrogen receptor α by demethylation of DNA in estrogen receptor-negative human breast cancer.

Journal: PloS one 20120101

Title: [Peculiarities of pharmacological correction of acute toxic hepatopathies in patients with severe forms of acute alcohol intoxication].

Journal: Klinicheskaia meditsina 20120101

Title: The different induction mechanisms of growth arrest DNA damage inducible gene 45 β in human hepatoma cell lines.

Journal: Chemotherapy 20120101

Title: [Characteristics of the pharmacological treatment of toxic liver damage in patients with an alcohol abused syndrome and an acute severe ethanol poison].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

Title: Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20120101

Title: [Intrahepatic induction of endogenous S-adenosyl-L-methionine against the background of various ways of administration of methionine-succinate complex and its role in drug-induced liver lesion correction].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk 20120101

Title: Reprogramming of gene expression during compression wood formation in pine: coordinated modulation of S-adenosylmethionine, lignin and lignan related genes.

Journal: BMC plant biology 20120101

Title: [Principles and perspectives of primary biliary cirrhosis therapy].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20120101

Title: [Clinical signs of endothelial disorders in patients with severe sepsis].

Journal: Anesteziologiia i reanimatologiia 20120101

Title: Identification of new ligands for the methionine biosynthesis transcriptional regulator (MetJ) by FAC-MS.

Journal: Journal of molecular microbiology and biotechnology 20120101

Title: [Hepatoprotectors in addictive medicine].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

Title: [Pathogenetic therapy of metabolic syndrome at the stage of visceral lesions].

Journal: Klinicheskaia meditsina 20120101

Title: Genes encoding Cher-TPR fusion proteins are predominantly found in gene clusters encoding chemosensory pathways with alternative cellular functions.

Journal: PloS one 20120101

Title: RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins.

Journal: Methods in enzymology 20120101

Title: Inhibition of P-glycoprotein-mediated transport by S-adenosylmethionine and cynarin in multidrug-resistant human uterine sarcoma MES-SA/Dx5 cells.

Journal: Journal of biological regulators and homeostatic agents 20120101

Title: Genetic modification and bioprocess optimization for S-Adenosyl-L-methionine biosynthesis.

Journal: Sub-cellular biochemistry 20120101

Title: CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment.

Journal: Drug metabolism and drug interactions 20120101

Title: Mechanism of isoprenylcysteine carboxyl methylation from the crystal structure of the integral membrane methyltransferase ICMT.

Journal: Molecular cell 20111223

Title: Synthesis of an azide-bearing N-mustard analogue of S-adenosyl-L-methionine.

Journal: The Journal of organic chemistry 20111216

Title: Arabidopsis calcium-binding mitochondrial carrier proteins as potential facilitators of mitochondrial ATP-import and plastid SAM-import.

Journal: FEBS letters 20111215

Title: Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation.

Journal: Journal of the American Chemical Society 20111214

Title: Pneumocystis S-adenosylmethionine transport: a potential drug target.

Journal: American journal of respiratory cell and molecular biology 20111201

Title: Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: a crucial role for nuclear p47(phox).

Journal: Molecular and cellular biochemistry 20111201

Title: S-Adenosylmethionine-dependent alkylation reactions: when are radical reactions used?

Journal: Bioorganic chemistry 20111201

Title: Biochemical disorders associated with antiproliferative effect of dehydroepiandrosterone in hepatoma cells as revealed by LC-based metabolomics.

Journal: Biochemical pharmacology 20111201

Title: Structural characterization of BVU_3255, a methyltransferase from human intestine antibiotic resistant pathogen Bacteroides vulgatus.

Journal: Journal of structural biology 20111201

Title: Proteomic analysis of a sea-ice diatom: salinity acclimation provides new insight into the dimethylsulfoniopropionate production pathway.

Journal: Plant physiology 20111201

Title: The PRPP synthetase spectrum: what does it demonstrate about nucleotide syndromes?

Journal: Nucleosides, nucleotides & nucleic acids 20111201

Title: S K-edge XAS and DFT calculations on SAM dependent pyruvate formate-lyase activating enzyme: nature of interaction between the Fe4S4 cluster and SAM and its role in reactivity.

Journal: Journal of the American Chemical Society 20111123

Title: RAM/Fam103a1 is required for mRNA cap methylation.

Journal: Molecular cell 20111118

Title: Elucidation of the methyl transfer mechanism catalyzed by chalcone O-methyltransferase: a density functional study.

Journal: Journal of computational chemistry 20111115

Title: A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans.

Journal: Cell 20111111

Title: Synthesis and biochemical evaluation of δ(2)-isoxazoline derivatives as DNA methyltransferase 1 inhibitors.

Journal: Journal of medicinal chemistry 20111110

Title: Structure-guided design of a methyl donor cofactor that controls a viral histone H3 lysine 27 methyltransferase activity.

Journal: Journal of medicinal chemistry 20111110

Title: Enzymatic methyl transfer: role of an active site residue in generating active site compaction that correlates with catalytic efficiency.

Journal: Journal of the American Chemical Society 20111102

Title: Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells.

Journal: Breast cancer research and treatment 20111101

Title: Folic acid supplementation during early hepatocarcinogenesis: cellular and molecular effects.

Journal: International journal of cancer 20111101

Title: Oxidative stress is implicated in arsenic-induced neural tube defects in chick embryos.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20111101

Title: Computational investigation of the substrate recognition mechanism of protein D-aspartyl (L-isoaspartyl) O-methyltransferase by docking and molecular dynamics simulation studies and application to interpret size exclusion chromatography data.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101

Title: Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors.

Journal: Molecular bioSystems 20111101

Title: S-adenosyl-L-methionine treatment for alcoholic liver disease: a double-blinded, randomized, placebo-controlled trial.

Journal: Alcoholism, clinical and experimental research 20111101

Title: Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1.

Journal: Organic & biomolecular chemistry 20111026

Title: In vitro phosphinate methylation by PhpK from Kitasatospora phosalacinea.

Journal: Biochemistry 20111025

Title: Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas.

Journal: The Journal of biological chemistry 20111021

Title: The structure of a tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer.

Journal: Structure (London, England : 1993) 20111012

Title: Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function.

Journal: American journal of human genetics 20111007

Title: Copper deficiency exacerbates bile duct ligation-induced liver injury and fibrosis in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20111001

Title: Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.

Journal: PLoS pathogens 20111001

Title: Natural supplements for mental health. Some complementary and alternative therapies may be worth trying.

Journal: The Harvard mental health letter 20111001

Title: Structural basis of substrate recognition in human nicotinamide N-methyltransferase.

Journal: Biochemistry 20110913

Title: Structural basis of substrate methylation and inhibition of SMYD2.

Journal: Structure (London, England : 1993) 20110907

Title: Complex biotransformations catalyzed by radical S-adenosylmethionine enzymes.

Journal: The Journal of biological chemistry 20110902

Title: Trichloroethylene induces methylation of the Serca2 promoter in H9c2 cells and embryonic heart.

Journal: Cardiovascular toxicology 20110901

Title: A maternal dietary pattern characterised by fish and seafood in association with the risk of congenital heart defects in the offspring.

Journal: BJOG : an international journal of obstetrics and gynaecology 20110901

Title: Vitamin-dependent methionine metabolism and alcoholic liver disease.

Journal: Advances in nutrition (Bethesda, Md.) 20110901

Title: High bone concentrations of homocysteine are associated with altered bone morphology in humans.

Journal: The British journal of nutrition 20110801

Title: Arabidopsis cell-free extract, ACE, a new in vitro translation system derived from Arabidopsis callus cultures.

Journal: Plant & cell physiology 20110801

Title: Leishmania donovani: proteasome-mediated down-regulation of methionine adenosyltransferase.

Journal: Parasitology 20110801

Title: Sulfatases and a radical S-adenosyl-L-methionine (AdoMet) enzyme are key for mucosal foraging and fitness of the prominent human gut symbiont, Bacteroides thetaiotaomicron.

Journal: The Journal of biological chemistry 20110722

Title: Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling.

Journal: ACS chemical biology 20110715

Title: Probing the reaction mechanism of spore photoproduct lyase (SPL) via diastereoselectively labeled dinucleotide SP TpT substrates.

Journal: Journal of the American Chemical Society 20110713

Title: Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.

Journal: RNA (New York, N.Y.) 20110701

Title: Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.

Journal: Nutrition research (New York, N.Y.) 20110701

Title: Characterization of NocL involved in thiopeptide nocathiacin I biosynthesis: a [4Fe-4S] cluster and the catalysis of a radical S-adenosylmethionine enzyme.

Journal: The Journal of biological chemistry 20110617

Title: Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay.

Journal: Analytical chemistry 20110615

Title: Global DNA methylation in the mouse liver is affected by methyl deficiency and arsenic in a sex-dependent manner.

Journal: Archives of toxicology 20110601

Title: S-adenosylmethionine prevents the up regulation of Toll-like receptor (TLR) signaling caused by chronic ethanol feeding in rats.

Journal: Experimental and molecular pathology 20110601

Title: A high-throughput absorbance-based assay for methionine produced by methionine aminopeptidase using S-adenosyl-L-methionine synthetase.

Journal: Journal of biomolecular screening 20110601

Title: Hypoxia induces genomic DNA demethylation through the activation of HIF-1α and transcriptional upregulation of MAT2A in hepatoma cells.

Journal: Molecular cancer therapeutics 20110601

Title: Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue.

Journal: The FEBS journal 20110601

Title: Generation of adenosyl radical from S-adenosylmethionine (SAM) in biotin synthase.

Journal: Journal of inorganic biochemistry 20110601

Title: A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop.

Journal: RNA (New York, N.Y.) 20110601

Title: Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae.

Journal: RNA (New York, N.Y.) 20110601

Title: HIV-associated Pneumocystis pneumonia.

Journal: Proceedings of the American Thoracic Society 20110601

Title: Complementary and alternative medicine for the treatment of major depressive disorder.

Journal: Canadian family physician Medecin de famille canadien 20110601

Title: Direct evidence for methyl group coordination by carbon-oxygen hydrogen bonds in the lysine methyltransferase SET7/9.

Journal: The Journal of biological chemistry 20110527

Title: Structural basis for methyl transfer by a radical SAM enzyme.

Journal: Science (New York, N.Y.) 20110527

Title: Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues.

Journal: Journal of the American Chemical Society 20110525

Title: Crystal structures and enzymatic properties of a triamine/agmatine aminopropyltransferase from Thermus thermophilus.

Journal: Journal of molecular biology 20110520

Title: The effects of dietary supplementation of methionine on genomic stability and p53 gene promoter methylation in rats.

Journal: Mutation research 20110518

Title: Mechanistic studies of the radical S-adenosyl-L-methionine enzyme DesII: EPR characterization of a radical intermediate generated during its catalyzed dehydrogenation of TDP-D-quinovose.

Journal: Journal of the American Chemical Society 20110518

Title: Concentrations of unmetabolized folic acid and primary folate forms in plasma after folic acid treatment in older adults.

Journal: Metabolism: clinical and experimental 20110501

Title: Evidence for the efficacy of complementary and alternative medicines in the management of osteoarthritis: a systematic review.

Journal: Rheumatology (Oxford, England) 20110501

Title: Effect of S-adenosylmethionine on neointimal formation after balloon injury in obese diabetic rats.

Journal: Cardiovascular research 20110501

Title: S-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway.

Journal: The Journal of pharmacology and experimental therapeutics 20110501

Title: Ethanol exposure modulates hepatic S-adenosylmethionine and S-adenosylhomocysteine levels in the isolated perfused rat liver through changes in the redox state of the NADH/NAD(+) system.

Journal: Biochimica et biophysica acta 20110501

Title: The mPlrp2 and mClps genes are involved in the hydrolysis of retinyl esters in the mouse liver.

Journal: Journal of lipid research 20110501

Title: The role of S-adenosyl methionine in preventing FOLFOX-induced liver toxicity: a retrospective analysis in patients affected by resected colorectal cancer treated with adjuvant FOLFOX regimen.

Journal: Expert opinion on drug safety 20110501

Title: Phloem-specific expression of Yang cycle genes and identification of novel Yang cycle enzymes in Plantago and Arabidopsis.

Journal: The Plant cell 20110501

Title: Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex.

Journal: PLoS pathogens 20110501

Title: [Pay more attention to standardizing the diagnosis and treatment of intrahepatic cholestasis of pregnancy].

Journal: Zhonghua fu chan ke za zhi 20110501

Title: S-adenosyl-L-methionine induces compaction of nascent peptide chain inside the ribosomal exit tunnel upon translation arrest in the Arabidopsis CGS1 gene.

Journal: The Journal of biological chemistry 20110429

Title: A radically different mechanism for S-adenosylmethionine-dependent methyltransferases.

Journal: Science (New York, N.Y.) 20110429

Title: Biochemistry. The two faces of SAM.

Journal: Science (New York, N.Y.) 20110429

Title: Mechanistic studies on transcriptional coactivator protein arginine methyltransferase 1.

Journal: Biochemistry 20110426

Title: Characterization of the N-methyltransferase activities of the multifunctional polypeptide cyclosporin synthetase.

Journal: Chemistry & biology 20110422

Title: Mechanism of Vibrio cholerae autoinducer-1 biosynthesis.

Journal: ACS chemical biology 20110415

Title: S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.

Journal: European journal of cell biology 20110401

Title: Radicals from S-adenosylmethionine and their application to biosynthesis.

Journal: Current opinion in chemical biology 20110401

Title: Thymidylate synthase gene polymorphisms and markers of DNA methylation capacity.

Journal: Molecular genetics and metabolism 20110401

Title: Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast.

Journal: The FEBS journal 20110401

Title: The C. elegans PRMT-3 possesses a type III protein arginine methyltransferase activity.

Journal: Journal of receptor and signal transduction research 20110401

Title: The cardiovascular inhibition functions of hydrogen sulfide within the nucleus tractus solitarii are mediated by the activation of KATP channels and glutamate receptors mechanisms.

Journal: Die Pharmazie 20110401

Title: [Function of luxS gene in sulfurmetabolism of Streptococcus mutans].

Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20110401

Title: DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.

Journal: The Journal of nutritional biochemistry 20110301

Title: Mthfd1 is a modifier of chemically induced intestinal carcinogenesis.

Journal: Carcinogenesis 20110301

Title: Impairment of methyl cycle affects mitochondrial methyl availability and glutathione level in Down's syndrome.

Journal: Molecular genetics and metabolism 20110301

Title: Active site mapping and substrate specificity of bacterial Hen1, a manganese-dependent 3' terminal RNA ribose 2'O-methyltransferase.

Journal: RNA (New York, N.Y.) 20110301

Title: Radical-mediated enzymatic carbon chain fragmentation-recombination.

Journal: Nature chemical biology 20110301

Title: Enzymology: Radical break-up, blissful make-up.

Journal: Nature chemical biology 20110301

Title: Small molecule inhibitors that selectively block dengue virus methyltransferase.

Journal: The Journal of biological chemistry 20110225

Title: Methyltransferase-directed derivatization of 5-hydroxymethylcytosine in DNA.

Journal: Angewandte Chemie (International ed. in English) 20110225

Title: Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.

Journal: The Journal of biological chemistry 20110211

Title: Changes in Presenilin 1 gene methylation pattern in diet-induced B vitamin deficiency.

Journal: Neurobiology of aging 20110201

Title: Determination of cystathionine beta-synthase activity in human plasma by LC-MS/MS: potential use in diagnosis of CBS deficiency.

Journal: Journal of inherited metabolic disease 20110201

Title: Functional and structural evaluation of cysteine residues in the human arsenic (+3 oxidation state) methyltransferase (hAS3MT).

Journal: Biochimie 20110201

Title: Radical SAM activation of the B12-independent glycerol dehydratase results in formation of 5'-deoxy-5'-(methylthio)adenosine and not 5'-deoxyadenosine.

Journal: Biochemistry 20110201

Title: Folic acid effects on s-adenosylmethionine, s-adenosylhomocysteine, and DNA methylation in patients with intermediate hyperhomocysteinemia.

Journal: Journal of the American College of Nutrition 20110201

Title: A chemical method for labeling lysine methyltransferase substrates.

Journal: Chembiochem : a European journal of chemical biology 20110124

Title: QM/MM free energy simulations of salicylic acid methyltransferase: effects of stabilization of TS-like structures on substrate specificity.

Journal: The journal of physical chemistry. B 20110120

Title: Pharmacological activation and genetic manipulation of cystathionine beta-synthase alter circulating levels of homocysteine and hydrogen sulfide in mice.

Journal: European journal of pharmacology 20110110

Title: Possible regulation of trehalose metabolism by methylation in Saccharomyces cerevisiae.

Journal: Journal of cellular physiology 20110101

Title: Specificity shifts in the rRNA and tRNA nucleotide targets of archaeal and bacterial m5U methyltransferases.

Journal: RNA (New York, N.Y.) 20110101

Title: Nitric oxide synthase inhibitors and cerebral vasospasm.

Journal: Acta neurochirurgica. Supplement 20110101

Title: Phosphoprotein affinity purification identifies proteins involved in S-adenosyl-L-methionine-induced enhancement of antibiotic production in Streptomyces coelicolor.

Journal: The Journal of antibiotics 20110101

Title: Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism.

Journal: Molecular microbiology 20110101

Title: Functional analysis of an acid adaptive DNA adenine methyltransferase from Helicobacter pylori 26695.

Journal: PloS one 20110101

Title: [Treatment of obstetric cholestasis with polyunsaturated phosphatidylcholine and ursodeoxycholic acid].

Journal: Ginekologia polska 20110101

Title: [Comparative study of remaxol and ademethionine effects on reparative regeneration processes in the liver subjected to surgical intervention].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20110101

Title: HC-Pro silencing suppressor significantly alters the gene expression profile in tobacco leaves and flowers.

Journal: BMC plant biology 20110101

Title: [Diagnosis and treatment of intrahepatic cholestasis in chronic diseases of the liver].

Journal: Terapevticheskii arkhiv 20110101

Title: Identification and characterization of the Chlamydia trachomatis L2 S-adenosylmethionine transporter.

Journal: mBio 20110101

Title: [Intrahepatic cholestasis in chronic liver diseases].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20110101

Title: S-adenosyl-L-methionine activates actinorhodin biosynthesis by increasing autophosphorylation of the Ser/Thr protein kinase AfsK in Streptomyces coelicolor A3(2).

Journal: Bioscience, biotechnology, and biochemistry 20110101

Title: Modeling a new water channel that allows SET9 to dimethylate p53.

Journal: PloS one 20110101

Title: Prospective randomized clinical trial assessing the efficacy of Denamarin for prevention of CCNU-induced hepatopathy in tumor-bearing dogs.

Journal: Journal of veterinary internal medicine 20110101

Title: Individual variations in inorganic arsenic metabolism associated with AS3MT genetic polymorphisms.

Journal: International journal of molecular sciences 20110101

Title: Amelioration of D-galactosamine-induced acute liver injury in rats by dietary supplementation with betaine derived from sugar beet molasses.

Journal: Bioscience, biotechnology, and biochemistry 20110101

Title: Genome mining for radical SAM protein determinants reveals multiple sactibiotic-like gene clusters.

Journal: PloS one 20110101

Title: [Comparative study of hepatoprotective action of remaxol, reamberin and ademethionine in liver injury induced by antituberculosis drugs (experimental study)].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

Title: Properties and crystal structure of methylenetetrahydrofolate reductase from Thermus thermophilus HB8.

Journal: PloS one 20110101

Title: Structural mechanism of S-adenosyl methionine binding to catechol O-methyltransferase.

Journal: PloS one 20110101

Title: Recognition of S-adenosylmethionine by riboswitches.

Journal: Wiley interdisciplinary reviews. RNA 20110101

Title: Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme.

Journal: PloS one 20110101

Title: Comparative effects of triflusal, S-adenosylmethionine, and dextromethorphan over intestinal ischemia/reperfusion injury.

Journal: TheScientificWorldJournal 20110101

Title: A conformational switch in the active site of BT_2972, a methyltransferase from an antibiotic resistant pathogen B. thetaiotaomicron.

Journal: PloS one 20110101

Title: [Induction of endogenous s-adenosyl-l-methionine in hepatocytes during pharmacological correction of experimental acute toxic and chronic drug-induced liver injury].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20110101

Title: Cloning and functional analysis of the GSH1/MET1 gene complementing cysteine and glutathione auxotrophy of the methylotrophic yeast Hansenula polymorpha.

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101

Title: Clinical depression: an evidence-based integrative complementary medicine treatment model.

Journal: Alternative therapies in health and medicine 20110101

Title: [S-adenosyl L-methionine in CNS diseases].

Journal: Psychiatria polska 20110101

Title: Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus.

Journal: BMC bioinformatics 20110101

Title: SAM recognition and conformational switching mechanism in the Bacillus subtilis yitJ S box/SAM-I riboswitch.

Journal: Journal of molecular biology 20101217

Title: Metabolome analysis revealed increase in S-methylcysteine and phosphatidylisopropanolamine synthesis upon L-cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica.

Journal: The Journal of biological chemistry 20101210

Title: High-level expression and reconstitution of active Cfr, a radical-SAM rRNA methyltransferase that confers resistance to ribosome-acting antibiotics.

Journal: Protein expression and purification 20101201

Title: S-adenosylmethionine decreases the peak blood alcohol levels 3 h after an acute bolus of ethanol by inducing alcohol metabolizing enzymes in the liver.

Journal: Experimental and molecular pathology 20101201

Title: Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9.

Journal: Bioorganic & medicinal chemistry 20101201

Title: O-carboxyl- and N-methyltransferases active on plant aquaporins.

Journal: Plant & cell physiology 20101201

Title: Discrepancy in response and remission rates for SAMe-treated patients in a double-blind, randomized clinical trial.

Journal: The American journal of psychiatry 20101201

Title: Biochemical research elucidating metabolic pathways in Pneumocystis.

Journal: Parasite (Paris, France) 20101201

Title: Biotin synthase exhibits burst kinetics and multiple turnovers in the absence of inhibition by products and product-related biomolecules.

Journal: Biochemistry 20101123

Title: Some more comments on 'folate deficiency in chronic pancreatitis'.

Journal: JOP : Journal of the pancreas 20101109

Title: A 'radical dance' in thiamin biosynthesis: mechanistic analysis of the bacterial hydroxymethylpyrimidine phosphate synthase.

Journal: Angewandte Chemie (International ed. in English) 20101108

Title: Förster resonance energy transfer measurements of cofactor-dependent effects on protein arginine N-methyltransferase homodimerization.

Journal: Protein science : a publication of the Protein Society 20101101

Title: Mechanisms and cell signaling in alcoholic liver disease.

Journal: Biological chemistry 20101101

Title: Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20101012

Title: Interaction of PqqE and PqqD in the pyrroloquinoline quinone (PQQ) biosynthetic pathway links PqqD to the radical SAM superfamily.

Journal: Chemical communications (Cambridge, England) 20101007

Title: Current understanding of the factors regulating methionine content in vegetative tissues of higher plants.

Journal: Amino acids 20101001

Title: SAM domain-dependent activity of PfTKL3, an essential tyrosine kinase-like kinase of the human malaria parasite Plasmodium falciparum.

Journal: Cellular and molecular life sciences : CMLS 20101001

Title: New insights into the mechanism of arsenite methylation with the recombinant human arsenic (+3) methyltransferase (hAS3MT).

Journal: Biochimie 20101001

Title: Analysis of trace degradation products (decarboxylated diastereoisomers) of S-adenosylmethionine by electrophoresis in capillaries with cationic coatings (N-methylpolyvinylpyridinium or divalent barium).

Journal: Electrophoresis 20101001

Title: S-adenosyl-L-methionine regulation of the cardiac ryanodine receptor involves multiple mechanisms.

Journal: Biochemistry 20100907

Title: Characterization of a Vitis vinifera cv. Cabernet Sauvignon 3',5'-O-methyltransferase showing strong preference for anthocyanins and glycosylated flavonols.

Journal: Phytochemistry 20100901

Title: Ethylene and nitric oxide involvement in the up-regulation of key genes related to iron acquisition and homeostasis in Arabidopsis.

Journal: Journal of experimental botany 20100901

Title: Using complementary and alternative medicines for depression.

Journal: The Journal of clinical psychiatry 20100901

Title: Temporal study of acetaminophen (APAP) and S-adenosyl-L-methionine (SAMe) effects on subcellular hepatic SAMe levels and methionine adenosyltransferase (MAT) expression and activity.

Journal: Toxicology and applied pharmacology 20100815

Title: Atomistic details of the ligand discrimination mechanism of S(MK)/SAM-III riboswitch.

Journal: The journal of physical chemistry. B 20100805

Title: Regulation of homocysteine metabolism and methylation in human and mouse tissues.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100801

Title: Herbivore-induced SABATH methyltransferases of maize that methylate anthranilic acid using s-adenosyl-L-methionine.

Journal: Plant physiology 20100801

Title: Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation.

Journal: Birth defects research. Part A, Clinical and molecular teratology 20100801

Title: S-adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial.

Journal: The American journal of psychiatry 20100801

Title: Efficacy and safety of intravenous stronger neo-minophagen C and S-adenosyl-L-methionine in treatment of pregnant woman with chronic hepatitis B: a pilot study.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20100801

Title: S-adenosyl methionine (SAMe) augmentation in major depressive disorder.

Journal: The American journal of psychiatry 20100801

Title: Accessing protein methyltransferase and demethylase enzymology using microfluidic capillary electrophoresis.

Journal: Chemistry & biology 20100730

Title: Molecular characterization of O-methyltransferases involved in isoquinoline alkaloid biosynthesis in Coptis japonica.

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100721

Title: Molecular architecture of a C-3'-methyltransferase involved in the biosynthesis of D-tetronitrose.

Journal: Biochemistry 20100720

Title: [FeFe]-hydrogenase maturation: HydG-catalyzed synthesis of carbon monoxide.

Journal: Journal of the American Chemical Society 20100714

Title: Homology modeling and molecular dynamics simulations of HgiDII methyltransferase in complex with DNA and S-adenosyl-methionine: catalytic mechanism and interactions with DNA.

Journal: Journal of molecular modeling 20100701

Title: Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide.

Journal: Hepatology (Baltimore, Md.) 20100701

Title: Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.

Journal: Nutrition research (New York, N.Y.) 20100701

Title: High affinity S-Adenosylmethionine plasma membrane transporter of Leishmania is a member of the folate biopterin transporter (FBT) family.

Journal: The Journal of biological chemistry 20100625

Title: Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2'-O methyltransferase activity in dengue virus.

Journal: Virology 20100620

Title: Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain.

Journal: The Journal of biological chemistry 20100618

Title: Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme.

Journal: Nature 20100617

Title: An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases.

Journal: Analytical biochemistry 20100615

Title: Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.

Journal: The Journal of biological chemistry 20100611

Title: Homocysteine-lowering vitamins do not lower plasma S-adenosylhomocysteine in older people with elevated homocysteine concentrations.

Journal: The British journal of nutrition 20100601

Title: In vivo proton MR spectroscopy findings specific for adenylosuccinate lyase deficiency.

Journal: NMR in biomedicine 20100601

Title: Evidence for the efficacy of complementary and alternative medicines in the management of fibromyalgia: a systematic review.

Journal: Rheumatology (Oxford, England) 20100601

Title: SAMe prevents the up regulation of toll-like receptor signaling in Mallory-Denk body forming hepatocytes.

Journal: Experimental and molecular pathology 20100601

Title: SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model.

Journal: Experimental and molecular pathology 20100601

Title: The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats: the effect of feeding S-adenosylmethionine.

Journal: Experimental and molecular pathology 20100601

Title: Complementary and alternative medicine for major depressive disorder: a meta-analysis of patient characteristics, placebo-response rates, and treatment outcomes relative to standard antidepressants.

Journal: The Journal of clinical psychiatry 20100601

Title: S-Adenosyl-L-methionine ameliorates TNFalpha-induced insulin resistance in 3T3-L1 adipocytes.

Journal: Experimental & molecular medicine 20100531

Title: The major product ion of S-adenosyl-L-methionine arises from a neighbouring group reaction.

Journal: Rapid communications in mass spectrometry : RCM 20100530

Title: A consensus mechanism for Radical SAM-dependent dehydrogenation? BtrN contains two [4Fe-4S] clusters.

Journal: Biochemistry 20100511

Title: Methotrexate-induced myelopathy responsive to substitution of multiple folate metabolites.

Journal: Journal of neuro-oncology 20100501

Title: Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100501

Title: Analysis of the liver mitochondrial proteome in response to ethanol and S-adenosylmethionine treatments: novel molecular targets of disease and hepatoprotection.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100501

Title: Formation of spray-dried powder of S-adenosyl-L-methionine.

Journal: Biotechnology journal 20100501

Title: Oxidative stress and the pathogenesis of cholestasis.

Journal: Seminars in liver disease 20100501

Title: Hepatoprotective effects of antioxidants in chronic hepatitis C.

Journal: World journal of gastroenterology 20100421

Title: Binding of MetJ repressor to specific and nonspecific DNA and effect of S-adenosylmethionine on these interactions.

Journal: Biochemistry 20100420

Title: Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation.

Journal: Journal of proteome research 20100405

Title: Evaluation of phospholipid and liposomal S-adenosyl methionine for the treatment of liver injury in a murine model.

Journal: Journal of pharmaceutical sciences 20100401

Title: Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice.

Journal: Hepatology (Baltimore, Md.) 20100401

Title: S-Adenosylmethionine (SAM) and antibiotic biosynthesis: effect of external addition of SAM and of overexpression of SAM biosynthesis genes on novobiocin production in Streptomyces.

Journal: Archives of microbiology 20100401

Title: Anaerobic sulfatase-maturating enzyme--a mechanistic link with glycyl radical-activating enzymes?

Journal: The FEBS journal 20100401

Title: Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases.

Journal: Bioorganic & medicinal chemistry letters 20100401

Title: Folate, DNA damage and the aging brain.

Journal: Mechanisms of ageing and development 20100401

Title: [Efficacy and safety of ademetionine for treatment of drug-induced liver disease in children].

Journal: Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20100401

Title: Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.

Journal: Biochemistry 20100330

Title: RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA.

Journal: Journal of the American Chemical Society 20100324

Title: Enzyme-catalyzed transfer of a ketone group from an S-adenosylmethionine analogue: a tool for the functional analysis of methyltransferases.

Journal: Journal of the American Chemical Society 20100324

Title: Adenosyl radical: reagent and catalyst in enzyme reactions.

Journal: Chembiochem : a European journal of chemical biology 20100322

Title: Hepatoprotective effects of S-adenosyl-L-methionine against alcohol- and cytochrome P450 2E1-induced liver injury.

Journal: World journal of gastroenterology 20100321

Title: The antiviral protein viperin is a radical SAM enzyme.

Journal: FEBS letters 20100319

Title: Simultaneous analysis of catechol-O-methyl transferase activity, S-adenosylhomocysteine and adenosine.

Journal: Biomedical chromatography : BMC 20100301

Title: DNA methylation regulates adenosine A(2A) receptor cell surface expression levels.

Journal: Journal of neurochemistry 20100301

Title: Changes in the expression of methionine adenosyltransferase genes and S-adenosylmethionine homeostasis during hepatic stellate cell activation.

Journal: Hepatology (Baltimore, Md.) 20100301

Title: Idiosyncratically tuned switching behavior of riboswitch aptamer domains revealed by comparative small-angle X-ray scattering analysis.

Journal: RNA (New York, N.Y.) 20100301

Title: A vitamin/nutriceutical formulation improves memory and cognitive performance in community-dwelling adults without dementia.

Journal: The journal of nutrition, health & aging 20100301

Title: [The role of DNA methylation in the pathogenesis of adult idiopathic thrombocytopenic purpura].

Journal: Zhonghua nei ke za zhi 20100301

Title: Discrimination between closely related cellular metabolites by the SAM-I riboswitch.

Journal: Journal of molecular biology 20100226

Title: Binding of S-methyl-5'-thioadenosine and S-adenosyl-L-methionine to protein MJ0100 triggers an open-to-closed conformational change in its CBS motif pair.

Journal: Journal of molecular biology 20100226

Title: Stoichiometry of the redox neutral deamination and oxidative dehydrogenation reactions catalyzed by the radical SAM enzyme DesII.

Journal: Journal of the American Chemical Society 20100224

Title: [FeFe]-hydrogenase cyanide ligands derived from S-adenosylmethionine-dependent cleavage of tyrosine.

Journal: Angewandte Chemie (International ed. in English) 20100222

Title: Catalytic activity of the anaerobic tyrosine lyase required for thiamine biosynthesis in Escherichia coli.

Journal: The Journal of biological chemistry 20100219

Title: Post-translational modification of ribosomal proteins: structural and functional characterization of RimO from Thermotoga maritima, a radical S-adenosylmethionine methylthiotransferase.

Journal: The Journal of biological chemistry 20100219

Title: Enhanced one-carbon flux towards DNA methylation: Effect of dietary methyl supplements against gamma-radiation-induced epigenetic modifications.

Journal: Chemico-biological interactions 20100212

Title: Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette.

Journal: RNA (New York, N.Y.) 20100201

Title: Effects of salvianolic acids on oxidative stress and hepatic fibrosis in rats.

Journal: Toxicology and applied pharmacology 20100115

Title: Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa.

Journal: Neuroscience letters 20100114

Title: Impaired methylation as a novel mechanism for proteasome suppression in liver cells.

Journal: Biochemical and biophysical research communications 20100108

Title: Sources of S-adenosyl-L-homocysteine background in measuring protein arginine N-methyltransferase activity using tandem mass spectrometry.

Journal: Analytical biochemistry 20100101

Title: The logic of the hepatic methionine metabolic cycle.

Journal: Biochimica et biophysica acta 20100101

Title: Automatic policing of biochemical annotations using genomic correlations.

Journal: Nature chemical biology 20100101

Title: Methionine-deficient diet induces post-transcriptional downregulation of cystathionine β-synthase.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20100101

Title: Homocysteine metabolism and its relation to health and disease.

Journal: BioFactors (Oxford, England) 20100101

Title: S-adenosylmethionine prevents oxidative stress and modulates glutathione metabolism in TgCRND8 mice fed a B-vitamin deficient diet.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: Chromatin remodeling regulation by small molecules and metabolites.

Journal: Biochimica et biophysica acta 20100101

Title: S-adenosylmethionine is decreased in the cerebrospinal fluid of patients with Alzheimer's disease.

Journal: Neuro-degenerative diseases 20100101

Title: Adult Polyglucosan Body Disease (APBD): Anaplerotic diet therapy (Triheptanoin) and demonstration of defective methylation pathways.

Journal: Molecular genetics and metabolism 20100101

Title: Determination of S-adenosyl-l-methionine in fruits by capillary electrophoresis.

Journal: Phytochemical analysis : PCA 20100101

Title: [Acute toxic hepatitis at mushroom poisoning of the young child].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20100101

Title: Does methionine restriction cause hyperhomocysteinemia?

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20100101

Title: S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse.

Journal: PloS one 20100101

Title: Catechol-O-methyltransferase enzyme: cofactor S-adenosyl-L-methionine and related mechanisms.

Journal: International review of neurobiology 20100101

Title: Metabolic and evolutionary insights into the closely-related species Streptomyces coelicolor and Streptomyces lividans deduced from high-resolution comparative genomic hybridization.

Journal: BMC genomics 20100101

Title: An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain.

Journal: PloS one 20100101

Title: S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer.

Journal: International journal of biological sciences 20100101

Title: Biochemical control of CARM1 enzymatic activity by phosphorylation.

Journal: The Journal of biological chemistry 20091225

Title: An investigation of the catalytic mechanism of S-adenosylmethionine synthetase by QM/MM calculations.

Journal: Archives of biochemistry and biophysics 20091201

Title: Update and critique of natural remedies as antidepressant treatments.

Journal: Obstetrics and gynecology clinics of North America 20091201

Title: Comparative clinical trial of S-adenosylmethionine versus nabumetone for the treatment of knee osteoarthritis: an 8-week, multicenter, randomized, double-blind, double-dummy, Phase IV study in Korean patients.

Journal: Clinical therapeutics 20091201

Title: An enzyme-coupled continuous spectrophotometric assay for magnesium protoporphyrin IX methyltransferases.

Journal: Analytical biochemistry 20091115

Title: Simultaneous quantification of S-adenosyl methionine and S-adenosyl homocysteine in human plasma by stable-isotope dilution ultra performance liquid chromatography tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091115

Title: Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis.

Journal: The Journal of biological chemistry 20091113

Title: DNA hypomethylation induced by tributyltin, triphenyltin, and a mixture of these in Sebastiscus marmoratus liver.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20091108

Title: Can adenosine substitute for SAM-e as an adjunct in the treatment of depression?

Journal: Medical hypotheses 20091101

Title: A combinatorial interplay among the 1-aminocyclopropane-1-carboxylate isoforms regulates ethylene biosynthesis in Arabidopsis thaliana.

Journal: Genetics 20091101

Title: Analysis of S-adenosylmethionine and related sulfur metabolites in bacterial isolates of Pseudomonas aeruginosa (BAA-47) by liquid chromatography/electrospray ionization coupled to a hybrid linear quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20091101

Title: S-adenosyl-L-methionine restores photoreceptor function following acute retinal ischemia.

Journal: Visual neuroscience 20091101

Title: Characterization of RimO, a new member of the methylthiotransferase subclass of the radical SAM superfamily.

Journal: Biochemistry 20091027

Title: Pyrroloquinoline quinone biogenesis: demonstration that PqqE from Klebsiella pneumoniae is a radical S-adenosyl-L-methionine enzyme.

Journal: Biochemistry 20091027

Title: Complete reconstitution of a highly reducing iterative polyketide synthase.

Journal: Science (New York, N.Y.) 20091023

Title: Evolution of putrescine N-methyltransferase from spermidine synthase demanded alterations in substrate binding.

Journal: FEBS letters 20091020

Title: Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine.

Journal: Free radical biology & medicine 20091015

Title: Molecular basis of substrate promiscuity for the SAM-dependent O-methyltransferase NcsB1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.

Journal: Biochemistry 20091013

Title: Discovery of novel types of inhibitors of S-adenosylmethionine synthesis by virtual screening.

Journal: Journal of medicinal chemistry 20091008

Title: Characterization and mechanistic studies of DesII: a radical S-adenosyl-L-methionine enzyme involved in the biosynthesis of TDP-D-desosamine.

Journal: Journal of the American Chemical Society 20091007

Title: A lipid profile typifies the Beijing strains of Mycobacterium tuberculosis: identification of a mutation responsible for a modification of the structures of phthiocerol dimycocerosates and phenolic glycolipids.

Journal: The Journal of biological chemistry 20091002

Title: Effect of 40% restriction of dietary amino acids (except methionine) on mitochondrial oxidative stress and biogenesis, AIF and SIRT1 in rat liver.

Journal: Biogerontology 20091001

Title: S-adenosylmethionine and S-adenosylhomocysteine levels in the aging brain of APP/PS1 Alzheimer mice.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20091001

Title: A mediator of Rho-dependent invasion moonlights as a methionine salvage enzyme.

Journal: Molecular & cellular proteomics : MCP 20091001

Title: Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine.

Journal: Cardiovascular drugs and therapy 20091001

Title: Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults. V. Complementary and alternative medicine treatments.

Journal: Journal of affective disorders 20091001

Title: Methylation status and neurodegenerative markers in Parkinson disease.

Journal: Clinical chemistry 20091001

Title: Mutagenesis of the enolase-phosphatase gene in Xanthomonas oryzae pv. oryzae affects growth on methylthioadenosine and in vivo S-adenosylmethionine pools.

Journal: Archives of microbiology 20091001

Title: The Pseudomonas aeruginosa nirE gene encodes the S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase required for heme d(1) biosynthesis.

Journal: The FEBS journal 20091001

Title: Experimental hyperhomocysteinaemia: differences in tissue metabolites between homocystine and methionine feeding in a rat model.

Journal: Acta physiologica (Oxford, England) 20090901

Title: Polyamine biosynthesis impacts cellular folate requirements necessary to maintain S-adenosylmethionine and nucleotide pools.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090901

Title: Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives.

Journal: Marine drugs 20090901

Title: Glycine N-methyltransferase and regulation of S-adenosylmethionine levels.

Journal: The Journal of biological chemistry 20090821

Title: Dietary deficiency increases presenilin expression, gamma-secretase activity, and Abeta levels: potentiation by ApoE genotype and alleviation by S-adenosyl methionine.

Journal: Journal of neurochemistry 20090801

Title: Impaired liver regeneration in mice lacking glycine N-methyltransferase.

Journal: Hepatology (Baltimore, Md.) 20090801

Title: Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics.

Journal: Drug metabolism letters 20090801

Title: Aquifex aeolicus tRNA (N2,N2-guanine)-dimethyltransferase (Trm1) catalyzes transfer of methyl groups not only to guanine 26 but also to guanine 27 in tRNA.

Journal: The Journal of biological chemistry 20090731

Title: Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20090728

Title: S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases.

Journal: The Journal of biological chemistry 20090717

Title: New S-adenosyl-L-methionine analogues: synthesis and reactivity studies.

Journal: Organic letters 20090716

Title: Metabolic defects provide a spark for the epigenetic switch in cancer.

Journal: Free radical biology & medicine 20090715

Title: Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC-MS/MS and evaluation of their stability in mice tissues.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715

Title: S-Adenosylmethionine and methylthioadenosine inhibit cellular FLICE inhibitory protein expression and induce apoptosis in colon cancer cells.

Journal: Molecular pharmacology 20090701

Title: Mitochondrial S-adenosyl-L-methionine transport is insensitive to alcohol-mediated changes in membrane dynamics.

Journal: Alcoholism, clinical and experimental research 20090701

Title: SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers.

Journal: Plant molecular biology 20090701

Title: Optimization of L: -methionine feeding strategy for improving S-adenosyl-L: -methionine production by methionine adenosyltransferase overexpressed Pichia pastoris.

Journal: Applied microbiology and biotechnology 20090701

Title: Mechanistic investigations of anaerobic sulfatase-maturating enzyme: direct Cbeta H-atom abstraction catalyzed by a radical AdoMet enzyme.

Journal: Journal of the American Chemical Society 20090624

Title: Structure of the thiostrepton resistance methyltransferase.S-adenosyl-L-methionine complex and its interaction with ribosomal RNA.

Journal: The Journal of biological chemistry 20090619

Title: S-adenosylmethionine regulates thiopurine methyltransferase activity and decreases 6-mercaptopurine cytotoxicity in MOLT lymphoblasts.

Journal: Biochemical pharmacology 20090615

Title: Ethanol-induced liver injury and changes in sulfur amino acid metabolomics in glutathione peroxidase and catalase double knockout mice.

Journal: Journal of hepatology 20090601

Title: Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications.

Journal: Hepatology (Baltimore, Md.) 20090601

Title: Effects of selenium on the structure and function of recombinant human S-adenosyl-L-methionine dependent arsenic (+3 oxidation state) methyltransferase in E. coli.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090501

Title: Alcoholic liver disease and methionine metabolism.

Journal: Seminars in liver disease 20090501

Title: Dietary supplement S-adenosyl-L-methionine (AdoMet) effects on plasma homocysteine levels in healthy human subjects: a double-blind, placebo-controlled, randomized clinical trial.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20090501

Title: Therapeutic use of cytoprotective agents in canine and feline hepatobiliary disease.

Journal: The Veterinary clinics of North America. Small animal practice 20090501

Title: Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics.

Journal: Chemistry & biology 20090424

Title: Functional characterization and modulation of the DNA cleavage efficiency of type III restriction endonuclease EcoP15I in its interaction with two sites in the DNA target.

Journal: Journal of molecular biology 20090417

Title: Homocysteine and lipids: S-adenosyl methionine as a key intermediate.

Journal: FEBS letters 20090417

Title: Product inhibition in the radical S-adenosylmethionine family.

Journal: FEBS letters 20090417

Title: Experimental folate and vitamin B12 deficiency does not alter bone quality in rats.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090401

Title: Betaine prevents Mallory-Denk body formation in drug-primed mice by epigenetic mechanisms.

Journal: Experimental and molecular pathology 20090401

Title: Alternative treatments in pediatric bipolar disorder.

Journal: Child and adolescent psychiatric clinics of North America 20090401

Title: Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1.

Journal: Acta crystallographica. Section D, Biological crystallography 20090401

Title: Magnolia officinalis reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element-binding protein-1c.

Journal: Journal of pharmacological sciences 20090401

Title: Hepatic cystathionine beta-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations.

Journal: Journal of nutritional science and vitaminology 20090401

Title: [Optimization of high-cell-density fermentation process for S-adenosyl-L-methionine production].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20090401

Title: Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells.

Journal: Mutation research 20090331

Title: Protein residues that control the reaction trajectory in S-adenosylmethionine radical enzymes: mutagenesis of asparagine 153 and aspartate 155 in Escherichia coli biotin synthase.

Journal: Biochemistry 20090324

Title: New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues of S-adenosylmethionine.

Journal: Journal of medicinal chemistry 20090312

Title: Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells.

Journal: Cell research 20090301

Title: Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone.

Journal: Bone 20090301

Title: Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation.

Journal: The Journal of clinical endocrinology and metabolism 20090301

Title: Major depressive disorder and nutritional medicine: a review of monotherapies and adjuvant treatments.

Journal: Nutrition reviews 20090301

Title: Identification of stable S-adenosylmethionine (SAM) analogues derivatised with bioorthogonal tags: effect of ligands on the affinity of the E. coli methionine repressor, MetJ, for its operator DNA.

Journal: Organic & biomolecular chemistry 20090221

Title: An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene.

Journal: Proteins 20090215

Title: Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies.

Journal: Toxicology and applied pharmacology 20090215

Title: Taurine supplementation improves the utilization of sulfur-containing amino acids in rats continually administrated alcohol.

Journal: The Journal of nutritional biochemistry 20090201

Title: Liposome dependent delivery of S-adenosyl methionine to cells by liposomes: a potential treatment for liver disease.

Journal: Journal of pharmaceutical sciences 20090201

Title: Structure-function relationships in methionine adenosyltransferases.

Journal: Cellular and molecular life sciences : CMLS 20090201

Title: In utero ethanol exposure impairs defenses against experimental group B streptococcus in the term Guinea pig lung.

Journal: Alcoholism, clinical and experimental research 20090201

Title: Anaerobic functionalization of unactivated C-H bonds.

Journal: Current opinion in chemical biology 20090201

Title: Pharmacokinetic properties of S-adenosylmethionine after oral and intravenous administration of its tosylate disulfate salt: a multiple-dose, open-label, parallel-group study in healthy Chinese volunteers.

Journal: Clinical therapeutics 20090201

Title: Reaction of AdoMet with ThiC generates a backbone free radical.

Journal: Biochemistry 20090120

Title: Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism.

Journal: The Journal of biological chemistry 20090116

Title: Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus.

Journal: Journal of molecular biology 20090109

Title: Complementary and alternative medicine for perinatal depression.

Journal: Journal of affective disorders 20090101

Title: Improvement of aggressive behavior and quality of life impairment following S-adenosyl-methionine (SAM-e) augmentation in schizophrenia.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090101

Title: S-adenosyl-L-methionine co-administration prevents the ethanol-elicited dissociation of hepatic mitochondrial ribosomes in male rats.

Journal: Alcoholism, clinical and experimental research 20090101

Title: Resveratrol supplementation worsen the dysregulation of genes involved in hepatic lipid homeostasis observed in hyperhomocysteinemic mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101

Title: Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism.

Journal: The American journal of clinical nutrition 20090101

Title: The polyamine and histamine metabolic interplay in cancer and chronic inflammation.

Journal: Current opinion in clinical nutrition and metabolic care 20090101

Title: S-Adenosyl-L-methionine increases serum BUN and creatinine in cisplatin-treated mice.

Journal: Archives of medical research 20090101

Title: Dietary selenium (Se) and copper (Cu) interact to affect homocysteine metabolism in rats.

Journal: Biological trace element research 20090101

Title: Possible role of S-adenosylmethionine, S-adenosylhomocysteine, and polyunsaturated fatty acids in predementia syndromes and Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20090101

Title: Application of fluorescent measurements for characterization of riboswitch-ligand interactions.

Journal: Methods in molecular biology (Clifton, N.J.) 20090101

Title: Dietary deficiency in folate and vitamin E under conditions of oxidative stress increases phospho-tau levels: potentiation by ApoE4 and alleviation by S-adenosylmethionine.

Journal: Journal of Alzheimer's disease : JAD 20090101

Title: Polyunsaturated fatty acid and S-adenosylmethionine supplementation in predementia syndromes and Alzheimer's disease: a review.

Journal: TheScientificWorldJournal 20090101

Title: Boron deprivation decreases liver S-adenosylmethionine and spermidine and increases plasma homocysteine and cysteine in rats.

Journal: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20090101

Title: Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20090101

Title: Tyrosine, cysteine, and S-adenosyl methionine stimulate in vitro [FeFe] hydrogenase activation.

Journal: PloS one 20090101

Title: Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child.

Journal: PloS one 20090101

Title: [Lipid peroxidation and antioxidant system status in patients with acute myeloblast leukemia and toxic damage of the liver].

Journal: Likars'ka sprava 20090101

Title: A new 1'-methylenedisulfide deoxyribose that forms an efficient cross-link to DNA cytosine-5 methyltransferase (DNMT).

Journal: Journal of the American Chemical Society 20081231

Title: Excessive S-adenosyl-L-methionine-dependent methylation increases levels of methanol, formaldehyde and formic acid in rat brain striatal homogenates: possible role in S-adenosyl-L-methionine-induced Parkinson's disease-like disorders.

Journal: Life sciences 20081219

Title: Folate and S-adenosylmethionine modulate synaptic activity in cultured cortical neurons: acute differential impact on normal and apolipoprotein-deficient mice.

Journal: Physical biology 20081219

Title: Active cystathionine beta-synthase can be expressed in heme-free systems in the presence of metal-substituted porphyrins or a chemical chaperone.

Journal: The Journal of biological chemistry 20081212

Title: Spectroscopic study of the cobalamin-dependent methionine synthase in the activation conformation: effects of the Y1139 residue and S-adenosylmethionine on the B12 cofactor.

Journal: Journal of the American Chemical Society 20081203

Title: Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates.

Journal: Clinica chimica acta; international journal of clinical chemistry 20081201

Title: Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats.

Journal: Clinical nutrition (Edinburgh, Scotland) 20081201

Title: Crystal structure of tRNA N2,N2-guanosine dimethyltransferase Trm1 from Pyrococcus horikoshii.

Journal: Journal of molecular biology 20081121

Title: Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis.

Journal: The Journal of biological chemistry 20081107

Title: Antifungal activity of 25-azalanosterol against Candida species.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20081101

Title: Assays for S-adenosylmethionine (AdoMet/SAM)-dependent methyltransferases.

Journal: Current protocols in toxicology 20081101

Title: Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet.

Journal: Brain research 20081027

Title: Effects of different glycerol feeding strategies on S-adenosyl-l-methionine biosynthesis by P(GAP)-driven Pichia pastoris overexpressing methionine adenosyltransferase.

Journal: Journal of biotechnology 20081010

Title: Ergot alkaloid biosynthesis in Aspergillus fumigatus. Overproduction and biochemical characterization of a 4-dimethylallyltryptophan N-methyltransferase.

Journal: The Journal of biological chemistry 20081003

Title: The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet.

Journal: Digestive diseases and sciences 20081001

Title: A hydrophilic-interaction chromatography tandem mass spectrometry method for quantitation of serum s-adenosylmethionine in patients infected with human immunodeficiency virus.

Journal: Clinica chimica acta; international journal of clinical chemistry 20081001

Title: Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice.

Journal: Laboratory investigation; a journal of technical methods and pathology 20081001

Title: S-adenosylmethionine and proliferation: new pathways, new targets.

Journal: Biochemical Society transactions 20081001

Title: Crystal structures of the SAM-III/S(MK) riboswitch reveal the SAM-dependent translation inhibition mechanism.

Journal: Nature structural & molecular biology 20081001

Title: Discovery of sphingosine 1-O-methyltransferase in rat kidney and liver homogenates.

Journal: Acta pharmacologica Sinica 20081001

Title: [Pre-L-methionine feeding strategy for S-adenosyl-L-methionine fermentative production].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20081001

Title: Crystal structure of the Thermus thermophilus 16 S rRNA methyltransferase RsmC in complex with cofactor and substrate guanosine.

Journal: The Journal of biological chemistry 20080926

Title: S-Adenosyl-L-methionine hydrolase (adenosine-forming), a conserved bacterial and archaeal protein related to SAM-dependent halogenases.

Journal: Chembiochem : a European journal of chemical biology 20080922

Title: ThiC is an [Fe-S] cluster protein that requires AdoMet to generate the 4-amino-5-hydroxymethyl-2-methylpyrimidine moiety in thiamin synthesis.

Journal: Biochemistry 20080902

Title: Complementary and alternative medicine in the treatment of bipolar disorder--a review of the evidence.

Journal: Journal of affective disorders 20080901

Title: S-adenosyl-L-methionine decreases the elevated hepatotoxicity induced by Fas agonistic antibody plus acute ethanol pretreatment in mice.

Journal: Archives of biochemistry and biophysics 20080901

Title: Elevated serum levels of S-adenosylhomocysteine, but not homocysteine, are associated with cardiovascular disease in stage 5 chronic kidney disease patients.

Journal: Clinica chimica acta; international journal of clinical chemistry 20080901

Title: Decreased DNA methyltransferase 3A and 3B mRNA expression in peripheral blood mononuclear cells and increased plasma SAH concentration in adult patients with idiopathic thrombocytopenic purpura.

Journal: Journal of clinical immunology 20080901

Title: The methylation, neurotransmitter, and antioxidant connections between folate and depression.

Journal: Alternative medicine review : a journal of clinical therapeutic 20080901

Title: Wheat coleoptile endonuclease Wen2 is dependent on S-adenosyl-L-methionine and sensitive to DNA methylation status.

Journal: Biochemistry. Biokhimiia 20080901

Title: Are nutritional supplements ready for prime time?

Journal: The Journal of clinical psychiatry 20080901

Title: Mechanistic study on the reaction of a radical SAM dehydrogenase BtrN by electron paramagnetic resonance spectroscopy.

Journal: Biochemistry 20080826

Title: 3-Methylarginine from Pseudomonas syringae pv. syringae 22d/93 suppresses the bacterial blight caused by its close relative Pseudomonas syringae pv. glycinea.

Journal: Chembiochem : a European journal of chemical biology 20080811

Title: Lentivirus mediated shRNA interference targeting MAT2B induces growth-inhibition and apoptosis in hepatocelluar carcinoma.

Journal: World journal of gastroenterology 20080807

Title: Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women.

Journal: European journal of clinical nutrition 20080801

Title: S-adenosyl-L-methionine attenuates oxidative stress and hepatic stellate cell activation in an ethanol-LPS-induced fibrotic rat model.

Journal: Shock (Augusta, Ga.) 20080801

Title: Deficiency in l-serine deaminase results in abnormal growth and cell division of Escherichia coli K-12.

Journal: Molecular microbiology 20080801

Title: Photoaffinity labeling and mutational analysis of 24-C-sterol methyltransferase defines the AdoMet binding site.

Journal: Lipids 20080801

Title: Maternal global methylation status and risk of congenital heart diseases.

Journal: Obstetrics and gynecology 20080801

Title: Analysis of AI-2/LuxS-dependent transcription in Campylobacter jejuni strain 81-176.

Journal: Foodborne pathogens and disease 20080801

Title: Melatonin exerts a more potent effect than S-adenosyl-l-methionine against iron metabolism disturbances, oxidative stress and tissue injury induced by obstructive jaundice in rats.

Journal: Chemico-biological interactions 20080730

Title: S-Adenosyl-l-methionine activates the cardiac ryanodine receptor.

Journal: Biochemical and biophysical research communications 20080711

Title: Interplay between cellular methyl metabolism and adaptive efflux during oncogenic transformation from chronic arsenic exposure in human cells.

Journal: The Journal of biological chemistry 20080711

Title: Structural, functional and calorimetric investigation of MosA, a dihydrodipicolinate synthase from Sinorhizobium meliloti l5-30, does not support involvement in rhizopine biosynthesis.

Journal: Chembiochem : a European journal of chemical biology 20080702

Title: Random mutagenesis and recombination of sam1 gene by integrating error-prone PCR with staggered extension process.

Journal: Biotechnology letters 20080701

Title: A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1.

Journal: Molecular and cellular biochemistry 20080701

Title: Hyperglycemia-induced membrane lipid peroxidation and elevated homocysteine levels are poorly attenuated by exogenous folate in embryonic chick brains.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080701

Title: Juvenile hormone acid O-methyltransferase in Drosophila melanogaster.

Journal: Insect biochemistry and molecular biology 20080701

Title: Reduced brain choline in homocystinuria due to remethylation defects.

Journal: Neurology 20080701

Title: S-adenosylmethionine mediates glutathione efficacy by increasing glutathione S-transferase activity: implications for S-adenosyl methionine as a neuroprotective dietary supplement.

Journal: Journal of Alzheimer's disease : JAD 20080701

Title: Anaerobic sulfatase-maturating enzymes, first dual substrate radical S-adenosylmethionine enzymes.

Journal: The Journal of biological chemistry 20080627

Title: Crystal structures of human 108V and 108M catechol O-methyltransferase.

Journal: Journal of molecular biology 20080627

Title: Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8.

Journal: Biochemistry 20080624

Title: Ethanol inhibits methionine adenosyltransferase II activity and S-adenosylmethionine biosynthesis and enhances caspase-3-dependent cell death in T lymphocytes: relevance to alcohol-induced immunosuppression.

Journal: The Journal of nutritional biochemistry 20080601

Title: Riboswitch effectors as protein enzyme cofactors.

Journal: RNA (New York, N.Y.) 20080601

Title: The biochemical structure and function of methylenetetrahydrofolate reductase provide the rationale to interpret the epidemiological results on the risk for infants with Down syndrome.

Journal: American journal of medical genetics. Part A 20080601

Title: Nonsurgical resolution of gallbladder mucocele in two dogs.

Journal: Journal of the American Veterinary Medical Association 20080601

Title: S-adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation.

Journal: Hepatology (Baltimore, Md.) 20080501

Title: An allosteric mechanism for switching between parallel tracks in mammalian sulfur metabolism.

Journal: PLoS computational biology 20080501

Title: Exploring the mechanisms behind S-adenosylmethionine (SAMe) in the treatment of osteoarthritis.

Journal: Critical reviews in food science and nutrition 20080501

Title: Comparison of the effects of buthioninesulfoximine and phorone on the metabolism of sulfur-containing amino acids in rat liver.

Journal: Biochemical and biophysical research communications 20080418

Title: A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism.

Journal: The Journal of biological chemistry 20080411

Title: Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.

Journal: The Journal of biological chemistry 20080404

Title: Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study.

Journal: Clinical science (London, England : 1979) 20080401

Title: S-Adenosylmethionine induces BldH and activates secondary metabolism by involving the TTA-codon control of bldH expression in Streptomyces lividans.

Journal: Archives of microbiology 20080401

Title: B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice.

Journal: Molecular and cellular neurosciences 20080401

Title: Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.

Journal: Hepatology (Baltimore, Md.) 20080401

Title: Overexpression of yeast S-adenosylmethionine synthetase metK in Streptomyces actuosus leads to increased production of nosiheptide.

Journal: Applied microbiology and biotechnology 20080401

Title: Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: critical role of S-adenosyl methionine.

Journal: The journal of nutrition, health & aging 20080401

Title: The differential NF-kB modulation by S-adenosyl-L-methionine, N-acetylcysteine and quercetin on the promotion stage of chemical hepatocarcinogenesis.

Journal: Free radical research 20080401

Title: Riboswitches that sense S-adenosylmethionine and S-adenosylhomocysteine.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20080401

Title: Oxygen vectors used for S-adenosylmethionine production in recombinant Pichia pastoris with sorbitol as supplemental carbon source.

Journal: Journal of bioscience and bioengineering 20080401

Title: Riboswitches that sense S-adenosylhomocysteine and activate genes involved in coenzyme recycling.

Journal: Molecular cell 20080328

Title: Biochemical and genetic analysis of the phosphoethanolamine methyltransferase of the human malaria parasite Plasmodium falciparum.

Journal: The Journal of biological chemistry 20080321

Title: Mechanism and tissue specificity of nicotine-mediated lung S-adenosylmethionine reduction.

Journal: The Journal of biological chemistry 20080321

Title: Folate deprivation increases tau phosphorylation by homocysteine-induced calcium influx and by inhibition of phosphatase activity: Alleviation by S-adenosyl methionine.

Journal: Brain research 20080314

Title: Reactivity and reaction order in acylhomoserine lactone formation by Pseudomonas aeruginosa RhlI.

Journal: Biochemistry 20080304

Title: Beneficial drugs for liver diseases.

Journal: Journal of applied toxicology : JAT 20080301

Title: Homocysteine-mediated PPARalpha,gamma DNA methylation and its potential pathogenic mechanism in monocytes.

Journal: DNA and cell biology 20080301

Title: Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes.

Journal: Molecular and cellular biology 20080301

Title: Ribosome stacking defines CGS1 mRNA degradation sites during nascent peptide-mediated translation arrest.

Journal: Plant & cell physiology 20080301

Title: S-Adenosylmethionine in cell growth, apoptosis and liver cancer.

Journal: Journal of gastroenterology and hepatology 20080301

Title: [Protection effects of S-adenosyl-L-methionine on lead-exposed rats during development and its mechanism of long-term potentiation].

Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20080301

Title: A universal competitive fluorescence polarization activity assay for S-adenosylmethionine utilizing methyltransferases.

Journal: Analytical biochemistry 20080215

Title: Alpha anomer of 5-aza-2'-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells.

Journal: Biochemical pharmacology 20080215

Title: Folding of the SAM aptamer is determined by the formation of a K-turn-dependent pseudoknot.

Journal: Biochemistry 20080212

Title: Comparison of S-adenosyl-L-methionine (SAMe) and N-acetylcysteine (NAC) protective effects on hepatic damage when administered after acetaminophen overdose.

Journal: Toxicology 20080203

Title: S-adenosylmethionine and its products.

Journal: Amino acids 20080201

Title: Folate status and S-adenosylmethionine/S-adenosylhomocysteine ratio in colorectal adenocarcinoma in humans.

Journal: European journal of clinical nutrition 20080201

Title: Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women.

Journal: Clinica chimica acta; international journal of clinical chemistry 20080201

Title: S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting the epigenetic memory.

Journal: Hepatology (Baltimore, Md.) 20080201

Title: Complementary medicines in pediatric bipolar disorder.

Journal: Minerva pediatrica 20080201

Title: Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA.

Journal: Journal of molecular biology 20080125

Title: The histamine N-methyltransferase T105I polymorphism affects active site structure and dynamics.

Journal: Biochemistry 20080122

Title: Dietary supplements for osteoarthritis.

Journal: American family physician 20080115

Title: S-adenosyl L-methionine inhibits azoxymethane-induced colonic aberrant crypt foci in F344 rats and suppresses human colon cancer Caco-2 cell growth in 3D culture.

Journal: International journal of cancer 20080101

Title: Ethanol-induced increased endogenous homocysteine levels and decreased ratios of SAM/SAH are only partially attenuated by exogenous glycine in developing chick brains.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080101

Title: Discovery and characterization of a marine bacterial SAM-dependent chlorinase.

Journal: Nature chemical biology 20080101

Title: Expression of secreted His-tagged S-adenosylmethionine synthetase in the methylotrophic yeast Pichia pastoris and its characterization, one-step purification, and immobilization.

Journal: Biotechnology progress 20080101

Title: Mammalian cytosine DNA methyltransferase Dnmt1: enzymatic mechanism, novel mechanism-based inhibitors, and RNA-directed DNA methylation.

Journal: Current medicinal chemistry 20080101

Title: Detection and quantitation of the activity of DNA methyltransferases using a biotin/avidin microplate assay.

Journal: Methods in molecular biology (Clifton, N.J.) 20080101

Title: The Radical SAM Superfamily.

Journal: Critical reviews in biochemistry and molecular biology 20080101

Title: [Pathogenesis and progress in treatment of neonatal total parenteral nutrition-associated cholestasis].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20080101

Title: Antiapoptotic role of S-adenosyl-l-methionine against hydrochloric acid induced cell death in Saccharomyces cerevisiae.

Journal: Biochimica et biophysica acta 20080101

Title: Effect of S-adenosylmethionine tablets on the reduction of age-related mental decline in dogs: a double-blinded, placebo-controlled trial.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20080101

Title: Methylation status in healthy subjects with normal and high serum folate concentration.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20080101

Title: S-Adenosylhomocysteine hydrolase overexpression in HEK-293 cells: effect on intracellular adenosine levels, cell viability, and DNA methylation.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: Transition state analogues in quorum sensing and SAM recycling.

Journal: Nucleic acids symposium series (2004) 20080101

Title: Methionine metabolism in an animal model of sepsis.

Journal: Clinical chemistry and laboratory medicine 20080101

Title: Requirement of RIZ1 for cancer prevention by methyl-balanced diet.

Journal: PloS one 20080101

Title: Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation.

Journal: PloS one 20080101

Title: Hypermethylation of Fads2 and altered hepatic fatty acid and phospholipid metabolism in mice with hyperhomocysteinemia.

Journal: The Journal of biological chemistry 20071221

Title: Characterization and mechanistic study of a radical SAM dehydrogenase in the biosynthesis of butirosin.

Journal: Journal of the American Chemical Society 20071212

Title: Cadmium induced oxidative stress in soybean plants also by the accumulation of delta-aminolevulinic acid.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20071201

Title: Influence of preconditioning-like hypoxia on the liver of developing methyl-deficient rats.

Journal: American journal of physiology. Endocrinology and metabolism 20071201

Title: Stability of plasma homocysteine, S-adenosylmethionine, and S-adenosylhomocysteine in EDTA, acidic citrate, and Primavette collection tubes.

Journal: Clinical chemistry 20071201

Title: Mechanism of enzymatic fluorination in Streptomyces cattleya.

Journal: Journal of the American Chemical Society 20071128

Title: Binding energy in the one-electron reductive cleavage of S-adenosylmethionine in lysine 2,3-aminomutase, a radical SAM enzyme.

Journal: Biochemistry 20071113

Title: AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-cytosine methyltransferase M.HhaI.

Journal: Journal of molecular biology 20071109

Title: The many flavors of hyperhomocyst(e)inemia: insights from transgenic and inhibitor-based mouse models of disrupted one-carbon metabolism.

Journal: Antioxidants & redox signaling 20071101

Title: Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.

Journal: Hepatology (Baltimore, Md.) 20071101

Title: S-adenosylmethionine attenuates oxidative liver injury in micropigs fed ethanol with a folate-deficient diet.

Journal: Alcoholism, clinical and experimental research 20071101

Title: Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver.

Journal: Hepatology (Baltimore, Md.) 20071101

Title: [Cholestasis of pregnancy].

Journal: Gastroenterologia y hepatologia 20071101

Title: Continuous enzymatic assay for histone lysine methyltransferases.

Journal: BioTechniques 20071101

Title: Genetic characterization of two S-adenosylmethionine-induced ABC transporters reveals their roles in modulations of secondary metabolism and sporulation in Streptomyces coelicolor M145.

Journal: Journal of microbiology and biotechnology 20071101

Title: S-adenosylmethionine-dependent protein methylation in mammalian cytosol via tyrphostin modification by catechol-O-methyltransferase.

Journal: The Journal of biological chemistry 20071019

Title: Depletion of S-adenosyl-l-methionine with cycloleucine potentiates cytochrome P450 2E1 toxicity in primary rat hepatocytes.

Journal: Archives of biochemistry and biophysics 20071015

Title: Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.

Journal: Journal of molecular biology 20071012

Title: Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA.

Journal: Journal of molecular biology 20071005

Title: The import of S-adenosylmethionine into the Golgi apparatus is required for the methylation of homogalacturonan.

Journal: Plant physiology 20071001

Title: S-adenosylmethionine as a biomarker for the early detection of lung cancer.

Journal: Chest 20071001

Title: Self-sacrifice in radical S-adenosylmethionine proteins.

Journal: Current opinion in chemical biology 20071001

Title: S-adenosyl-L-methionine:magnesium-protoporphyrin IX O-methyltransferase from Rhodobacter capsulatus: mechanistic insights and stimulation with phospholipids.

Journal: The Biochemical journal 20070915

Title: Study of bacteriophage T4-encoded Dam DNA (adenine-N6)-methyltransferase binding with substrates by rapid laser UV cross-linking.

Journal: The Journal of biological chemistry 20070907

Title: Supranormal dietary folic acid supplementation: effects on methionine metabolism in weanling rats.

Journal: The British journal of nutrition 20070901

Title: Crystal structure of SAM-dependent O-methyltransferase from pathogenic bacterium Leptospira interrogans.

Journal: Journal of structural biology 20070901

Title: Marked elevation in homocysteine and homocysteine sulfinic acid in the cerebrospinal fluid of lymphoma patients receiving intensive treatment with methotrexate.

Journal: International journal of clinical pharmacology and therapeutics 20070901

Title: [Efficacy and safety of heptral, vitamin B6 and folic acid during toxic hepatitis induced by CCL4].

Journal: Georgian medical news 20070901

Title: Two threonine residues required for role of AfsKav in controlling morphogenesis and avermectin production in Streptomyces avermitilis.

Journal: Journal of microbiology and biotechnology 20070901

Title: Structure-based activity prediction for an enzyme of unknown function.

Journal: Nature 20070816

Title: The carboxyl-terminal extension of yeast tRNA m5C methyltransferase enhances the catalytic efficiency of the amino-terminal domain.

Journal: The Journal of biological chemistry 20070810

Title: Homocysteine affects cardiomyocyte viability: concentration-dependent effects on reversible flip-flop, apoptosis and necrosis.

Journal: Apoptosis : an international journal on programmed cell death 20070801

Title: Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet.

Journal: Carcinogenesis 20070801

Title: Folate deprivation increases presenilin expression, gamma-secretase activity, and Abeta levels in murine brain: potentiation by ApoE deficiency and alleviation by dietary S-adenosyl methionine.

Journal: Journal of neurochemistry 20070801

Title: Testosterone regulation of renal cystathionine beta-synthase: implications for sex-dependent differences in plasma homocysteine levels.

Journal: American journal of physiology. Renal physiology 20070801

Title: Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.

Journal: Protein science : a publication of the Protein Society 20070801

Title: Homocysteine-mediated expression of SAHH, DNMTs, MBD2, and DNA hypomethylation potential pathogenic mechanism in VSMCs.

Journal: DNA and cell biology 20070801

Title: Nutraceuticals in the management of osteoarthritis.

Journal: Orthopedics 20070801

Title: S-adenosyl-L-methionine-dependent methyl transfer: observable precatalytic intermediates during DNA cytosine methylation.

Journal: Biochemistry 20070731

Title: S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701

Title: S-adenosylmethionine attenuates hepatic lipid synthesis in micropigs fed ethanol with a folate-deficient diet.

Journal: Alcoholism, clinical and experimental research 20070701

Title: Identification of a ubiG-like gene involved in ubiquinone biosynthesis from Chlamydophila pneumoniae AR39.

Journal: Letters in applied microbiology 20070701

Title: Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells.

Journal: Gastroenterology 20070701

Title: Functional characterization of the recombinant N-methyltransferase domain from the multienzyme enniatin synthetase.

Journal: Chembiochem : a European journal of chemical biology 20070618

Title: Protein interactions in the human methionine synthase-methionine synthase reductase complex and implications for the mechanism of enzyme reactivation.

Journal: Biochemistry 20070612

Title: Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: effects on protein-L-isoaspartyl methyltransferase activity.

Journal: Journal of hepatology 20070601

Title: Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency.

Journal: Molecular genetics and metabolism 20070601

Title: Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase.

Journal: Protein science : a publication of the Protein Society 20070601

Title: Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells.

Journal: Archives of biochemistry and biophysics 20070601

Title: S-adenosylmethionine exerts a protective effect against thioacetamide-induced injury in primary cultures of rat hepatocytes.

Journal: Alternatives to laboratory animals : ATLA 20070601

Title: gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells.

Journal: Journal of Alzheimer's disease : JAD 20070601

Title: Making the connections--the crucial role of metabolite transporters at the interface between chloroplast and cytosol.

Journal: FEBS letters 20070525

Title: The diverse members of the mitochondrial carrier family in plants.

Journal: FEBS letters 20070525

Title: DNA methylation status is not impaired in treated cystathionine beta-synthase (CBS) deficient patients.

Journal: Molecular genetics and metabolism 20070501

Title: Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.

Journal: Molecular genetics and metabolism 20070501

Title: Role of S-adenosyl-L-methionine in liver health and injury.

Journal: Hepatology (Baltimore, Md.) 20070501

Title: Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study.

Journal: Neurology 20070424

Title: A pathogenic linked mutation in the catalytic core of human cystathionine beta-synthase disrupts allosteric regulation and allows kinetic characterization of a full-length dimer.

Journal: Biochemistry 20070403

Title: Repair of alkylated DNA: recent advances.

Journal: DNA repair 20070401

Title: Folate restriction and methylenetetrahydrofolate reductase 677T polymorphism decreases adoMet synthesis via folate-dependent remethylation in human-transformed lymphoblasts.

Journal: Leukemia 20070401

Title: Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.

Journal: The American journal of clinical nutrition 20070401

Title: Abnormal folate metabolism in foetuses affected by neural tube defects.

Journal: Brain : a journal of neurology 20070401

Title: Recognition of age-damaged (R,S)-adenosyl-L-methionine by two methyltransferases in the yeast Saccharomyces cerevisiae.

Journal: The Journal of biological chemistry 20070323

Title: S-Adenosylmethionine in protozoan parasites: functions, synthesis and regulation.

Journal: Molecular and biochemical parasitology 20070301

Title: S-adenosylmethionine as an oxidant: the radical SAM superfamily.

Journal: Trends in biochemical sciences 20070301

Title: Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition.

Journal: The Journal of nutritional biochemistry 20070301

Title: S-adenosylmethionine and radical-based catalysis.

Journal: Amino acids 20070201

Title: Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway.

Journal: Journal of hepatology 20070201

Title: Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes.

Journal: Biochimica et biophysica acta 20070201

Title: Crystal structure and solution characterization of the activation domain of human methionine synthase.

Journal: The FEBS journal 20070201

Title: Adenosine metabolism and its effect on methylation potential in cultured cells: methodological considerations.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20070121

Title: Role of S-adenosylhomocysteine hydrolase in adenosine-induced apoptosis in HepG2 cells.

Journal: Experimental cell research 20070115

Title: S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis.

Journal: Neuroreport 20070108

Title: Long term low-dose arsenic exposure induces loss of DNA methylation.

Journal: Biochemical and biophysical research communications 20070105

Title: Modulation of DNA methyltransferase profile by methyl donor starvation followed by gamma irradiation.

Journal: Molecular and cellular biochemistry 20070101

Title: Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine.

Journal: The Biochemical journal 20070101

Title: Global metabolic changes following loss of a feedback loop reveal dynamic steady states of the yeast metabolome.

Journal: Metabolic engineering 20070101

Title: Comparison of S-Adenosyl-L-methionine and N-acetylcysteine protective effects on acetaminophen hepatic toxicity.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: Binding study of AfsK, a Ser/Thr kinase from Streptomyces coelicolor A3(2) and S-adenosyl-L-methionine.

Journal: FEMS microbiology letters 20070101

Title: Allosteric monofunctional aspartate kinases from Arabidopsis.

Journal: The FEBS journal 20070101

Title: Amino acids and the regulation of methyl balance in humans.

Journal: Current opinion in clinical nutrition and metabolic care 20070101

Title: Emerging aspects of gut sulfur amino acid metabolism.

Journal: Current opinion in clinical nutrition and metabolic care 20070101

Title: The role of methionine recycling for ethylene synthesis in Arabidopsis.

Journal: The Plant journal : for cell and molecular biology 20070101

Title: Cysteine supplementation decreases plasma homocysteine concentration in rats fed on a low-casein diet in rats.

Journal: Bioscience, biotechnology, and biochemistry 20070101

Title: Crystal structures of CbiL, a methyltransferase involved in anaerobic vitamin B biosynthesis, and CbiL in complex with S-adenosylhomocysteine--implications for the reaction mechanism.

Journal: The FEBS journal 20070101

Title: A method to study the expression of DNA methyltransferases in aging systems in vitro.

Journal: Methods in molecular biology (Clifton, N.J.) 20070101

Title: The role of one-carbon metabolism in schizophrenia and depression.

Journal: Harvard review of psychiatry 20070101

Title: Effects of dietary supplementation with N-acetyl cysteine, acetyl-L-carnitine and S-adenosyl methionine on cognitive performance and aggression in normal mice and mice expressing human ApoE4.

Journal: Neuromolecular medicine 20070101

Title: Metabolic regulatory properties of S-adenosylmethionine and S-adenosylhomocysteine.

Journal: Clinical chemistry and laboratory medicine 20070101

Title: Wheat endonuclease WEN1 dependent on S-adenosyl-L-methionine and sensitive to DNA methylation status.

Journal: Epigenetics 20070101

Title: Hydroxyl radical probing of tRNA (Gm18) methyltransferase [TrmH]-AdoMet-artificial tRNA ternary complex.

Journal: Nucleic acids symposium series (2004) 20070101

Title: Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.

Journal: BMC biochemistry 20070101

Title: Potentiation of arsenic neurotoxicity by folate deprivation: protective role of S-adenosyl methionine.

Journal: Nutritional neuroscience 20070101

Title: Priorities in the discovery of the implications of water channels in epilepsy and Duchenne muscular dystrophy.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20061231

Title: Catalysis in glycine N-methyltransferase: testing the electrostatic stabilization and compression hypothesis.

Journal: Biochemistry 20061219

Title: Nitric oxide modulates glutathione synthesis during endotoxemia.

Journal: Free radical biology & medicine 20061215

Title: Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism.

Journal: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20061205

Title: Protein arginine methylation: Cellular functions and methods of analysis.

Journal: Biochimica et biophysica acta 20061201

Title: Suppression of TNF-alpha production by S-adenosylmethionine in human mononuclear leukocytes is not mediated by polyamines.

Journal: Biological chemistry 20061201

Title: S-adenosylmethionine (SAM)-accumulating sake yeast suppresses acute alcohol-induced liver injury in mice.

Journal: Bioscience, biotechnology, and biochemistry 20061201

Title: Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses.

Journal: The Plant cell 20061201

Title: Supplementation with apple juice attenuates presenilin-1 overexpression during dietary and genetically-induced oxidative stress.

Journal: Journal of Alzheimer's disease : JAD 20061201

Title: Increase in S-adenosylhomocysteine content and its effect on the S-adenosylhomocysteine hydrolase activity under transient high plasma homocysteine levels in rats.

Journal: Journal of nutritional science and vitaminology 20061201

Title: Quantitative analysis of s-adenosylmethionine and s-adenosylhomocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061121

Title: Structural basis for the differential regulation of DNA by the methionine repressor MetJ.

Journal: The Journal of biological chemistry 20061110

Title: Functional categorization of the conserved basic amino acid residues in TrmH (tRNA (Gm18) methyltransferase) enzymes.

Journal: The Journal of biological chemistry 20061110

Title: DLPC and SAMe prevent alpha1(I) collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione.

Journal: Biochemical and biophysical research communications 20061110

Title: Mild folate deficiency induces a proatherosclerotic phenotype in endothelial cells.

Journal: Atherosclerosis 20061101

Title: S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20061101

Title: Molecular identification of an Arabidopsis S-adenosylmethionine transporter. Analysis of organ distribution, bacterial expression, reconstitution into liposomes, and functional characterization.

Journal: Plant physiology 20061101

Title: Arabidopsis SAMT1 defines a plastid transporter regulating plastid biogenesis and plant development.

Journal: The Plant cell 20061101

Title: PAGE separation of hemi-methylated or unmethylated oligonucleotide substrates to distinguish between maintenance and de novo DNA methyltranferase activity.

Journal: Journal of biochemical and biophysical methods 20061031

Title: Tandem riboswitch architectures exhibit complex gene control functions.

Journal: Science (New York, N.Y.) 20061013

Title: Interactions of cytokines, S-Adenosylmethionine, and S-Adenosylhomocysteine in alcohol-induced liver disease and immune suppression.

Journal: Journal of gastroenterology and hepatology 20061001

Title: L-NAME has opposite effects on the productions of S-adenosylhomocysteine and S-adenosylmethionine in V12-H-Ras and M-CR3B-Ras pheochromocytoma cells.

Journal: Neurochemical research 20061001

Title: Solvent-accessible cysteines in human cystathionine beta-synthase: crucial role of cysteine 431 in S-adenosyl-L-methionine binding.

Journal: Biochemistry 20060912

Title: Characterization of an active spore photoproduct lyase, a DNA repair enzyme in the radical S-adenosylmethionine superfamily.

Journal: The Journal of biological chemistry 20060908

Title: Exogenous glycine partially attenuates homocysteine-induced apoptosis and membrane peroxidation in chick embryos.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060901

Title: Osteoarthritis.

Journal: Disease-a-month : DM 20060901

Title: 4-Hydroxyphenylacetate decarboxylases: properties of a novel subclass of glycyl radical enzyme systems.

Journal: Biochemistry 20060808

Title: S-adenosylhomocysteine hydrolase deficiency in a 26-year-old man.

Journal: Journal of inherited metabolic disease 20060801

Title: S-Adenosyl-L-methionine: beyond the universal methyl group donor.

Journal: Phytochemistry 20060801

Title: Suppression of methionine-induced hyperhomocysteinemia by dietary eritadenine in rats.

Journal: Bioscience, biotechnology, and biochemistry 20060801

Title: Folate, the methionine cycle, and Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20060801

Title: Dietary and genetically-induced oxidative stress alter tau phosphorylation: influence of folate and apolipoprotein E deficiency.

Journal: Journal of Alzheimer's disease : JAD 20060801

Title: Gene silencing through methylation: an epigenetic intervention on Alzheimer disease.

Journal: Journal of Alzheimer's disease : JAD 20060801

Title: The effect of S-adenosylmethionine on CNS gene expression studied by cDNA microarray analysis.

Journal: Journal of Alzheimer's disease : JAD 20060801

Title: Homocysteine metabolism and various consequences of folate deficiency.

Journal: Journal of Alzheimer's disease : JAD 20060801

Title: Crystal structures of BchU, a methyltransferase involved in bacteriochlorophyll c biosynthesis, and its complex with S-adenosylhomocysteine: implications for reaction mechanism.

Journal: Journal of molecular biology 20060721

Title: Flipping off the riboswitch: RNA structures that control gene expression.

Journal: ACS chemical biology 20060721

Title: S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase.

Journal: Gastroenterology 20060701

Title: Structural biology: RNA switches function.

Journal: Nature 20060629

Title: Structure of the S-adenosylmethionine riboswitch regulatory mRNA element.

Journal: Nature 20060629

Title: Catalysis by the second class of tRNA(m1G37) methyl transferase requires a conserved proline.

Journal: Biochemistry 20060620

Title: Differential regulation of the JNK/AP-1 pathway by S-adenosylmethionine and methylthioadenosine in primary rat hepatocytes versus HuH7 hepatoma cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20060601

Title: Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans.

Journal: The Journal of antimicrobial chemotherapy 20060601

Title: Tolcapone decreases plasma levels of S-adenosyl-L-homocysteine and homocysteine in treated Parkinson's disease patients.

Journal: European journal of clinical pharmacology 20060601

Title: In vivo hydrolysis of S-adenosyl-L-methionine in Escherichia coli increases export of 5-methylthioribose.

Journal: Canadian journal of microbiology 20060601

Title: The active conformation of avilamycin A is conferred by AviX12, a radical AdoMet enzyme.

Journal: The Journal of biological chemistry 20060526

Title: S-adenosylmethionine but not glutathione protects against galactosamine-induced cytotoxicity in rat hepatocyte cultures.

Journal: Toxicology 20060515

Title: Coupling between protein and reaction dynamics in enzymatic processes: application of Grote-Hynes Theory to catechol O-methyltransferase.

Journal: Journal of the American Chemical Society 20060510

Title: Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver.

Journal: American journal of physiology. Endocrinology and metabolism 20060501

Title: Maternal polymorphisms 677C-T and 1298A-C of MTHFR, and 66A-G MTRR genes: is there any relationship between polymorphisms of the folate pathway, maternal homocysteine levels, and the risk for having a child with Down syndrome?

Journal: American journal of medical genetics. Part A 20060501

Title: In vivo hydrolysis of S-adenosylmethionine induces the met regulon of Escherichia coli.

Journal: Microbiology (Reading, England) 20060501

Title: Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor.

Journal: The Journal of biological chemistry 20060428

Title: Insights into cephamycin biosynthesis: the crystal structure of CmcI from Streptomyces clavuligerus.

Journal: Journal of molecular biology 20060428

Title: S-adenosyl-L-methionine for alcoholic liver diseases.

Journal: The Cochrane database of systematic reviews 20060419

Title: Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20060401

Title: S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20060401

Title: S-adenosylmethionine: jack of all trades and master of everything?

Journal: Biochemical Society transactions 20060401

Title: S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro.

Journal: Hepatology (Baltimore, Md.) 20060401

Title: Spectral and kinetic characterization of 7,8-diaminopelargonic acid synthase from Mycobacterium tuberculosis.

Journal: IUBMB life 20060401

Title: S-adenosyl-methionine decreases ethanol-induced apoptosis in primary hepatocyte cultures by a c-Jun N-terminal kinase activity-independent mechanism.

Journal: World journal of gastroenterology 20060328

Title: An enzyme-coupled continuous spectrophotometric assay for S-adenosylmethionine-dependent methyltransferases.

Journal: Analytical biochemistry 20060315

Title: Cofactor dependence of reduction potentials for [4Fe-4S]2+/1+ in lysine 2,3-aminomutase.

Journal: Biochemistry 20060314

Title: Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis.

Journal: Biochemistry 20060314

Title: Natural product diversification using a non-natural cofactor analogue of S-adenosyl-L-methionine.

Journal: Journal of the American Chemical Society 20060308

Title: Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet.

Journal: Journal of hepatology 20060301

Title: DLPC and SAMe combined prevent leptin-stimulated TIMP-1 production in LX-2 human hepatic stellate cells by inhibiting HO-mediated signal transduction.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20060301

Title: Let LuxS speak up in AI-2 signaling.

Journal: Trends in microbiology 20060301

Title: Therapy of NAFLD: antioxidants and cytoprotective agents.

Journal: Journal of clinical gastroenterology 20060301

Title: [Effect of feeding pre-L-methionine on high-cell-density fermentation for S-adenosyl-L-methionine production].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20060301

Title: Differential effects of dietary selenium (se) and folate on methyl metabolism in liver and colon of rats.

Journal: Biological trace element research 20060301

Title: [Ursodeoxycholic acid, S-adenosyl-L-methionine and their combinations in the treatment of gestational intrahepatic cholestasis (ICP)].

Journal: Ceska gynekologie 20060301

Title: [The impact of heptral, vitamin B6 and folic acid on the indices of hepatic biotransformation in toxic hepatitis].

Journal: Georgian medical news 20060301

Title: Allosteric threonine synthase. Reorganization of the pyridoxal phosphate site upon asymmetric activation through S-adenosylmethionine binding to a novel site.

Journal: The Journal of biological chemistry 20060224

Title: The 108M polymorph of human catechol O-methyltransferase is prone to deformation at physiological temperatures.

Journal: Biochemistry 20060221

Title: Synergistic protection by S-adenosylmethionine with vitamins C and E on liver injury induced by thioacetamide in rats.

Journal: Free radical biology & medicine 20060215

Title: A new method for isolation of S-adenosylmethionine (SAM)-accumulating yeast.

Journal: Applied microbiology and biotechnology 20060201

Title: Flavonoid 3'-O-methyltransferase from rice: cDNA cloning, characterization and functional expression.

Journal: Phytochemistry 20060201

Title: The Elongator subunit Elp3 contains a Fe4S4 cluster and binds S-adenosylmethionine.

Journal: Molecular microbiology 20060201

Title: Complementary medicines in psychiatry: review of effectiveness and safety.

Journal: The British journal of psychiatry : the journal of mental science 20060201

Title: The fluorinase from Streptomyces cattleya is also a chlorinase.

Journal: Angewandte Chemie (International ed. in English) 20060123

Title: Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.

Journal: Free radical biology & medicine 20060115

Title: Characterization of a methionine adenosyltransferase over-expressing strain in the trypanosomatid Leishmania donovani.

Journal: Biochimica et biophysica acta 20060101

Title: Protective effect of S-adenosylmethionine against galactosamine-induced injury of rat hepatocytes in primary culture.

Journal: Physiological research 20060101

Title: Quantification of S-adenosyl methionine in microbial cell extracts.

Journal: Biotechnology letters 20060101

Title: Chemical expansion of cofactor activity.

Journal: Nature chemical biology 20060101

Title: Glutathione-enhancing agents protect against steatohepatitis in a dietary model.

Journal: Journal of biochemical and molecular toxicology 20060101

Title: Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?

Journal: BioFactors (Oxford, England) 20060101

Title: Radical enzymes in anaerobes.

Journal: Annual review of microbiology 20060101

Title: Randomized prospective comparative study of ursodeoxycholic acid and S-adenosyl-L-methionine in the treatment of intrahepatic cholestasis of pregnancy.

Journal: Journal of perinatal medicine 20060101

Title: S-adenosylmethionine or 5'-methylthioadenosine are unable to prevent fumonisin B1 hepatotoxicity in mice despite increased oxidation in liver.

Journal: Journal of applied toxicology : JAT 20060101

Title: Effect of cell cycle growth arrest on global DNA methylation status in human lung epithelial-like (A549) cells.

Journal: In vivo (Athens, Greece) 20060101

Title: Structural studies of the purine and SAM binding riboswitches.

Journal: Cold Spring Harbor symposia on quantitative biology 20060101

Title: Synthesis of S-adenosyl-L-methionine analogs and their use for sequence-specific transalkylation of DNA by methyltransferases.

Journal: Nature protocols 20060101

Title: The role of nutritional therapy in alcoholic liver disease.

Journal: Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism 20060101

Title: Aspirin augments the concentration of endogenous hydrogen sulfide in mouse brain and liver.

Journal: Folia medica Cracoviensia 20060101

Title: Procainamide is a specific inhibitor of DNA methyltransferase 1.

Journal: The Journal of biological chemistry 20051209

Title: Inclusion of thiamine diphosphate and S-adenosylmethionine at their chemically active sites.

Journal: The Journal of organic chemistry 20051209

Title: The role of phospholipid methylation in 1-methyl-4-phenyl-pyridinium ion (MPP+)-induced neurotoxicity in PC12 cells.

Journal: Neurotoxicology 20051201

Title: In vitro and in vivo analysis of the major type I protein arginine methyltransferase from Trypanosoma brucei.

Journal: Molecular and biochemical parasitology 20051201

Title: The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii.

Journal: Protein science : a publication of the Protein Society 20051201

Title: The immediate-early ethylene response gene OsARD1 encodes an acireductone dioxygenase involved in recycling of the ethylene precursor S-adenosylmethionine.

Journal: The Plant journal : for cell and molecular biology 20051201

Title: Inhibitory effect of Epimedium extract on S-adenosyl-L-homocysteine hydrolase and biomethylation.

Journal: Life sciences 20051126

Title: Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase.

Journal: Journal of medicinal chemistry 20051117

Title: A deficiency in S-adenosylmethionine synthetase interrupts assembly of the septal ring in Escherichia coli K-12.

Journal: Molecular microbiology 20051101

Title: Sequence specificity and role of proximal amino acids of the histone H3 tail on catalysis of murine G9A lysine 9 histone H3 methyltransferase.

Journal: Biochemistry 20051004

Title: Effect of acute hyperhomocysteinemia on methylation potential of erythrocytes and on DNA methylation of lymphocytes in healthy male volunteers.

Journal: American journal of physiology. Renal physiology 20051001

Title: Structural and functional comparison of HemN to other radical SAM enzymes.

Journal: Biological chemistry 20051001

Title: The transmethylation cycle in the brain of Alzheimer patients.

Journal: Neuroscience letters 20050930

Title: An escape from Italy, the discovery of S-adenosylmethionine, and the biosynthesis of creatine by Giulio L. Cantoni. 1953.

Journal: The Journal of biological chemistry 20050923

Title: Biochemical characterization of the HydE and HydG iron-only hydrogenase maturation enzymes from Thermatoga maritima.

Journal: FEBS letters 20050912

Title: Protective effect of S-adenosylmethionine on cellular and mitochondrial membranes of rat hepatocytes against tert-butylhydroperoxide-induced injury in primary culture.

Journal: Chemico-biological interactions 20050910

Title: S-adenosylmethionine blocks collagen I production by preventing transforming growth factor-beta induction of the COL1A2 promoter.

Journal: The Journal of biological chemistry 20050902

Title: Exogenous AdoMet and its analogue sinefungin differentially influence DNA cleavage by R.EcoP15I--usefulness in SAGE.

Journal: Biochemical and biophysical research communications 20050902

Title: Diet-dependent survival of protein repair-deficient mice.

Journal: The Journal of nutritional biochemistry 20050901

Title: Paracoccidioides brasiliensis, paracoccidioidomycosis, and antifungal antibiotics.

Journal: Current drug targets. Infectious disorders 20050901

Title: A Leptospira interrogans enzyme with similarity to yeast Ste14p that methylates the 1-phosphate group of lipid A.

Journal: The Journal of biological chemistry 20050826

Title: Radical S-adenosylmethionine enzyme coproporphyrinogen III oxidase HemN: functional features of the [4Fe-4S] cluster and the two bound S-adenosyl-L-methionines.

Journal: The Journal of biological chemistry 20050812

Title: Stable-isotope dilution liquid chromatography-electrospray injection tandem mass spectrometry method for fast, selective measurement of S-adenosylmethionine and S-adenosylhomocysteine in plasma.

Journal: Clinical chemistry 20050801

Title: Tyr152 plays a central role in the catalysis of 1-aminocyclopropane-1-carboxylate synthase.

Journal: Journal of experimental botany 20050801

Title: Unusual pseudosubstrate specificity of a novel 3,5-dimethoxyphenol O-methyltransferase cloned from Ruta graveolens L.

Journal: Archives of biochemistry and biophysics 20050801

Title: In nucleo enzymatic assays for the identification and characterization of histone modifying activities.

Journal: Methods (San Diego, Calif.) 20050801

Title: A tertiary structural element in S box leader RNAs is required for S-adenosylmethionine-directed transcription termination.

Journal: Molecular microbiology 20050801

Title: Structure of a class II TrmH tRNA-modifying enzyme from Aquifex aeolicus.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20050801

Title: o-nitrobenzenesulfonamides in nucleoside synthesis: efficient 5'-aziridination of adenosine.

Journal: The Journal of organic chemistry 20050722

Title: DNA cytosine C5 methyltransferase Dnmt1: catalysis-dependent release of allosteric inhibition.

Journal: Biochemistry 20050712

Title: Removing a bottleneck in the Bacillus subtilis biotin pathway: bioA utilizes lysine rather than S-adenosylmethionine as the amino donor in the KAPA-to-DAPA reaction.

Journal: Biotechnology and bioengineering 20050705

Title: Stable isotope dilution-based accurate comparative quantification of nitrogen-containing metabolites in Arabidopsis thaliana T87 cells using in vivo (15)N-isotope enrichment.

Journal: Bioscience, biotechnology, and biochemistry 20050701

Title: Effects of betaine supplementation on hepatic metabolism of sulfur-containing amino acids in mice.

Journal: Journal of hepatology 20050601

Title: Human embryonic stem cell methyl cycle enzyme expression: modelling epigenetic programming in assisted reproduction?

Journal: Reproductive biomedicine online 20050601

Title: [Effect of heptral and folic acid on the hepatic functions during toxic hepatitis].

Journal: Georgian medical news 20050601

Title: Hepatic S-adenosylmethionine after maternal alcohol exposure on offspring rats.

Journal: Addiction biology 20050601

Title: Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis.

Journal: The Journal of biological chemistry 20050527

Title: Ligand-mediated anticodon conformational changes occur during tRNA methylation by a TrmD methyltransferase.

Journal: Biochemistry 20050503

Title: Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.

Journal: Clinical chemistry 20050501

Title: Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by alpha-naphthylisothiocyanate.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050501

Title: Expression of iron-acquisition-related genes in iron-deficient rice is co-ordinately induced by partially conserved iron-deficiency-responsive elements.

Journal: Journal of experimental botany 20050501

Title: Antioxidants as novel therapy in a murine model of colitis.

Journal: The Journal of nutritional biochemistry 20050501

Title: Mechanistic studies on the metabolic scission of thiazolidinedione derivatives to acyclic thiols.

Journal: Chemical research in toxicology 20050501

Title: Kinetics of homocysteine metabolism after moderate alcohol consumption.

Journal: Alcoholism, clinical and experimental research 20050501

Title: S-adenosyl-L-methionine: transcellular transport and uptake by Caco-2 cells and hepatocytes.

Journal: The Journal of pharmacy and pharmacology 20050501

Title: Effect of nicotine on lung S-adenosylmethionine and development of Pneumocystis pneumonia.

Journal: The Journal of biological chemistry 20050415

Title: The impact of metabolism on DNA methylation.

Journal: Human molecular genetics 20050415

Title: S-adenosylmethionine (SAMe) modulates interleukin-10 and interleukin-6, but not TNF, production via the adenosine (A2) receptor.

Journal: Biochimica et biophysica acta 20050415

Title: Homocysteine alterations in experimental cholestasis and its subsequent cirrhosis.

Journal: Life sciences 20050408

Title: Polyamine synthesis from proline in the developing porcine placenta.

Journal: Biology of reproduction 20050401

Title: In vivo evidence for the specificity of Plasmodium falciparum phosphoethanolamine methyltransferase and its coupling to the Kennedy pathway.

Journal: The Journal of biological chemistry 20050401

Title: mRNA guanylation catalyzed by the S-adenosylmethionine-dependent guanylyltransferase of bamboo mosaic virus.

Journal: The Journal of biological chemistry 20050401

Title: S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050401

Title: Residues distal from the active site that alter enzyme function in M.HhaI DNA cytosine methyltransferase.

Journal: Journal of biomolecular structure & dynamics 20050401

Title: Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine.

Journal: Biochemical pharmacology 20050401

Title: Regulation of trehalose metabolism by Adox and AdoMet in Saccharomyces cerevisiae.

Journal: Indian journal of experimental biology 20050401

Title: Effect of fasting on methionine adenosyltransferase expression and the methionine cycle in the mouse liver.

Journal: Journal of nutritional science and vitaminology 20050401

Title: Alcohol and liver cancer.

Journal: Alcohol (Fayetteville, N.Y.) 20050401

Title: Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer.

Journal: Alcohol (Fayetteville, N.Y.) 20050401

Title: Mechanistic investigations of lipoic acid biosynthesis in Escherichia coli: both sulfur atoms in lipoic acid are contributed by the same lipoyl synthase polypeptide.

Journal: Journal of the American Chemical Society 20050309

Title: MTX-induced white matter changes are associated with polymorphisms of methionine metabolism.

Journal: Neurology 20050308

Title: Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.

Journal: Metabolism: clinical and experimental 20050301

Title: Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.

Journal: Biological psychiatry 20050301

Title: Effect of piroxicam, metamizol, and S-adenosylmethionine in a murine model of experimental trichomoniasis.

Journal: Parasite (Paris, France) 20050301

Title: Specificity and mechanism of RNA cap guanine-N2 methyltransferase (Tgs1).

Journal: The Journal of biological chemistry 20050211

Title: Effect of S-adenosyl-L-methionine on the activation, proliferation and contraction of hepatic stellate cells.

Journal: European journal of pharmacology 20050210

Title: Aclacinomycin 10-hydroxylase is a novel substrate-assisted hydroxylase requiring S-adenosyl-L-methionine as cofactor.

Journal: The Journal of biological chemistry 20050204

Title: Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-{kappa}B and Mat1A genes in the early stages of rat liver carcinogenesis.

Journal: Carcinogenesis 20050201

Title: Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis.

Journal: Cancer research 20050201

Title: Evaluation of the influence of S-adenosylmethionine on systemic and hepatic effects of prednisolone in dogs.

Journal: American journal of veterinary research 20050201

Title: Lysophosphatidylcholine decreases locomotor activities and dopamine turnover rate in rats.

Journal: Neurotoxicology 20050101

Title: Fetal alcohol exposure impairs alveolar macrophage function via decreased glutathione availability.

Journal: Pediatric research 20050101

Title: Pyruvate formate-lyase activating enzyme: elucidation of a novel mechanism for glycyl radical formation.

Journal: Archives of biochemistry and biophysics 20050101

Title: The novel structure and chemistry of iron-sulfur clusters in the adenosylmethionine-dependent radical enzyme biotin synthase.

Journal: Archives of biochemistry and biophysics 20050101

Title: S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production.

Journal: Molecular and cellular neurosciences 20050101

Title: Autotoxicity, methylation and a road to the prevention of Parkinson's disease.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20050101

Title: The effect of methionine and S-adenosylmethionine on S-adenosylmethionine levels in the rat brain.

Journal: Journal of psychiatry & neuroscience : JPN 20050101

Title: The role of cystathionine beta-synthase in homocysteine metabolism.

Journal: Antioxidants & redox signaling 20050101

Title: Nonpharmacologic treatments for depression in patients with coronary heart disease.

Journal: Psychosomatic medicine 20050101

Title: The effects of S-adenosylmethionine on clinical pathology and redox potential in the red blood cell, liver, and bile of clinically normal cats.

Journal: Journal of veterinary internal medicine 20050101

Title: S-adenosylhomocysteine metabolism in different cell lines: effect of hypoxia and cell density.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101

Title: Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria.

Journal: Genome biology 20050101

Title: Natural history of S-adenosylmethionine-binding proteins.

Journal: BMC structural biology 20050101

Title: Levodopa intake increases plasma levels of S-adenosylmethionine in treated patients with Parkinson disease.

Journal: Clinical neuropharmacology 20050101

Title: Pathogenesis and treatment of alcoholic liver disease: progress over the last 50 years.

Journal: Roczniki Akademii Medycznej w Bialymstoku (1995) 20050101

Title: Effect of S-adenosylmethionine on age-induced hepatocyte damage in old Wistar rats.

Journal: Biogerontology 20050101

Title: Structural change of tRNA (Gm18) methyltransferase by binding of methyl donor analogues.

Journal: Nucleic acids symposium series (2004) 20050101

Title: S-Adenosylmethionine (SAMe) attenuates acetaminophen hepatotoxicity in C57BL/6 mice.

Journal: Toxicology letters 20041230

Title: Modulation of endotoxin stimulated interleukin-6 production in monocytes and Kupffer cells by S-adenosylmethionine (SAMe).

Journal: Cytokine 20041221

Title: Salt stress enhances xylem development and expression of S-adenosyl-L-methionine synthase in lignifying tissues of tomato plants.

Journal: Planta 20041201

Title: S-adenosyl-L-methionine (SAMe) as an adjunct for resistant major depressive disorder: an open trial following partial or nonresponse to selective serotonin reuptake inhibitors or venlafaxine.

Journal: Journal of clinical psychopharmacology 20041201

Title: Bacteriophage T4Dam DNA-(adenine-N(6))-methyltransferase. Comparison of pre-steady state and single turnover methylation of 40-mer duplexes containing two (un)modified target sites.

Journal: The Journal of biological chemistry 20041126

Title: MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA.

Journal: The Journal of biological chemistry 20041112

Title: Bioavailability and lack of toxicity of S-adenosyl-L-methionine (SAMe) in humans.

Journal: Pharmacotherapy 20041101

Title: Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid.

Journal: The Journal of biological chemistry 20041029

Title: Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine.

Journal: Biochemistry 20041026

Title: Isotope and elemental effects indicate a rate-limiting methyl transfer as the initial step in the reaction catalyzed by Escherichia coli cyclopropane fatty acid synthase.

Journal: Biochemistry 20041026

Title: DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo.

Journal: Oncogene 20041014

Title: Treatment of AIDS-associated myelopathy with L-methionine: a placebo-controlled study.

Journal: Neurology 20041012

Title: SAM domains can utilize similar surfaces for the formation of polymers and closed oligomers.

Journal: Journal of molecular biology 20041001

Title: S-adenosylmethionine radical enzymes.

Journal: Bioorganic chemistry 20041001

Title: Structure and function of radical SAM enzymes.

Journal: Current opinion in chemical biology 20041001

Title: Consequences of binding an S-adenosylmethionine analogue on the structure and dynamics of the thiopurine methyltransferase protein backbone.

Journal: Biochemistry 20040928

Title: Mutational analysis of ThiH, a member of the radical S-adenosylmethionine (AdoMet) protein superfamily.

Journal: The Journal of biological chemistry 20040924

Title: Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide.

Journal: Biochemistry 20040921

Title: Widespread activation of antibiotic biosynthesis by S-adenosylmethionine in streptomycetes.

Journal: FEMS microbiology letters 20040915

Title: The mechanism of target base attack in DNA cytosine carbon 5 methylation.

Journal: Biochemistry 20040914

Title: Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum.

Journal: Chembiochem : a European journal of chemical biology 20040906

Title: S-adenosylmethionine protects against intrabiliary glutathione degradation induced by long-term administration of cyclosporin A in the rat.

Journal: Toxicology 20040901

Title: In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl) phenyl]methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. I. Role of cytochrome P450, methyltransferases, flavin monooxygenases, and esterases.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040901

Title: In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl)-phenyl] methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. II. Identification of metabolites by liquid chromatography-tandem mass spectrometry.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040901

Title: N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.

Journal: The Journal of biological chemistry 20040827

Title: S-adenosylmethionine and Pneumocystis.

Journal: FEMS microbiology letters 20040815

Title: Improved rotorod performance and hyperactivity in mice deficient in a protein repair methyltransferase.

Journal: Behavioural brain research 20040812

Title: Differential protein expression analysis of Leishmania major reveals novel roles for methionine adenosyltransferase and S-adenosylmethionine in methotrexate resistance.

Journal: The Journal of biological chemistry 20040806

Title: Stopped-flow and mutational analysis of base flipping by the Escherichia coli Dam DNA-(adenine-N6)-methyltransferase.

Journal: Journal of molecular biology 20040806

Title: Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20040801

Title: Dimethyl sulfoxide stimulates the catalytic activity of de novo DNA methyltransferase 3a (Dnmt3a) in vitro.

Journal: Bioorganic chemistry 20040801

Title: S-Adenosylmethionine protects against acetaminophen-induced hepatotoxicity in mice.

Journal: Pharmacology 20040801

Title: Autoregulation of the gene for cystathionine gamma-synthase in Arabidopsis: post-transcriptional regulation induced by S-adenosylmethionine.

Journal: Biochemical Society transactions 20040801

Title: Homocysteine clearance and methylation flux rates in health and end-stage renal disease: association with S-adenosylhomocysteine.

Journal: American journal of physiology. Renal physiology 20040801

Title: Nutrition and alcoholic liver disease.

Journal: Seminars in liver disease 20040801

Title: How oligomerization contributes to the thermostability of an archaeon protein. Protein L-isoaspartyl-O-methyltransferase from Sulfolobus tokodaii.

Journal: The Journal of biological chemistry 20040730

Title: Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis.

Journal: The Journal of biological chemistry 20040723

Title: Effects of S-adenosylmethionine on intrabiliary glutathione degradation induced by long-term administration of cyclosporin A in the rat.

Journal: Toxicology 20040715

Title: A method for connecting solution-phase enzyme activity assays with immobilized format analysis by mass spectrometry.

Journal: Analytical chemistry 20040715

Title: S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-x(S).

Journal: Hepatology (Baltimore, Md.) 20040701

Title: Inhibitors of polyamine metabolism: review article.

Journal: Amino acids 20040701

Title: Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells.

Journal: The Journal of biological chemistry 20040625

Title: Small molecule regulators of protein arginine methyltransferases.

Journal: The Journal of biological chemistry 20040604

Title: Lipoyl synthase requires two equivalents of S-adenosyl-L-methionine to synthesize one equivalent of lipoic acid.

Journal: Biochemistry 20040601

Title: An origin for arsenobetaine involving bacterial formation of an arsenic-carbon bond.

Journal: FEMS microbiology letters 20040601

Title: Characterization of glycine N-methyltransferase from rabbit liver.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20040601

Title: S-Adenosyl methionine/S-adenosyl-L-homocysteine ratio determination by capillary electrophoresis employed as a monitoring tool for the antiviral effectiveness of adenosine analogs.

Journal: Electrophoresis 20040601

Title: Preparation of carbocyclic S-adenosylazamethionine accompanied by a practical synthesis of (-)-aristeromycin.

Journal: The Journal of organic chemistry 20040528

Title: Methionine metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can import S-adenosylmethionine from the cytosol.

Journal: The Journal of biological chemistry 20040521

Title: Antioxidant properties of S-adenosyl-L-methionine in Fe(2+)-initiated oxidations.

Journal: Free radical biology & medicine 20040515

Title: Enzymatic fluorination in Streptomyces cattleya takes place with an inversion of configuration consistent with an SN2 reaction mechanism.

Journal: Chembiochem : a European journal of chemical biology 20040503

Title: Methotrexate differentially affects growth of suspension and adherent cells.

Journal: The international journal of biochemistry & cell biology 20040501

Title: Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040501

Title: S-adenosylmethionine: nothing goes to waste.

Journal: Trends in biochemical sciences 20040501

Title: Levodopa elevates homocysteine: is this a problem?

Journal: Archives of neurology 20040501

Title: Detecting selection using a single genome sequence of M. tuberculosis and P. falciparum.

Journal: Nature 20040429

Title: Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity.

Journal: The Journal of biological chemistry 20040423

Title: Deletion of the Pemt gene increases progenitor cell mitosis, DNA and protein methylation and decreases calretinin expression in embryonic day 17 mouse hippocampus.

Journal: Brain research. Developmental brain research 20040419

Title: Starvation response in mouse liver shows strong correlation with life-span-prolonging processes.

Journal: Physiological genomics 20040413

Title: Post-translational formylglycine modification of bacterial sulfatases by the radical S-adenosylmethionine protein AtsB.

Journal: The Journal of biological chemistry 20040409

Title: Synthesis and evaluation of analogues of S-adenosyl-L-methionine, as inhibitors of the E. coli cyclopropane fatty acid synthase.

Journal: Bioorganic & medicinal chemistry letters 20040405

Title: Identification of the human mitochondrial S-adenosylmethionine transporter: bacterial expression, reconstitution, functional characterization and tissue distribution.

Journal: The Biochemical journal 20040401

Title: Influence of an altered methylation potential on mRNA methylation and gene expression in HepG2 cells.

Journal: Experimental cell research 20040401

Title: 5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes.

Journal: Hepatology (Baltimore, Md.) 20040401

Title: Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme.

Journal: Structure (London, England : 1993) 20040401

Title: O-Methylation of benzaldehyde derivatives by 'lignin specific' caffeic acid 3-O-methyltransferase.

Journal: Phytochemistry 20040401

Title: NMR regulatory analysis: determination and characterization of S-adenosyl-L-methionine in dietary supplements.

Journal: Die Pharmazie 20040401

Title: [Analysis on therapeutic effect of Western and Chinese drug in treating intrahepatic cholestasis pregnancy].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040401

Title: Structural studies of inhibition of S-adenosylmethionine synthetase by slow, tight-binding intermediate and product analogues.

Journal: Biochemistry 20040330

Title: Sequence-specific methyltransferase-induced labeling of DNA (SMILing DNA).

Journal: Chembiochem : a European journal of chemical biology 20040305

Title: Update on dietary supplements for depression.

Journal: Harvard women's health watch 20040301

Title: The inhibitory role of methylation on the binding characteristics of dopamine receptors and transporter.

Journal: Neuroscience research 20040301

Title: Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity.

Journal: The Journal of biological chemistry 20040227

Title: Crystal structure of the S-adenosylmethionine synthetase ternary complex: a novel catalytic mechanism of S-adenosylmethionine synthesis from ATP and Met.

Journal: Biochemistry 20040224

Title: Characterization of the cofactor composition of Escherichia coli biotin synthase.

Journal: Biochemistry 20040224

Title: Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.

Journal: Neurology 20040224

Title: Heterodimeric interactions among the 1-amino-cyclopropane-1-carboxylate synthase polypeptides encoded by the Arabidopsis gene family.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20040224

Title: Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.

Journal: Biochemistry 20040210

Title: Crystal structure and mechanism of a bacterial fluorinating enzyme.

Journal: Nature 20040205

Title: Quantification of serum and urinary S-adenosylmethionine and S-adenosylhomocysteine by stable-isotope-dilution liquid chromatography-mass spectrometry.

Journal: Clinical chemistry 20040201

Title: New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments.

Journal: Current gastroenterology reports 20040201

Title: Use of desferoxamine and S-adenosylmethionine to treat hemochromatosis in a red ruffed lemur (Varecia variegata ruber).

Journal: Comparative medicine 20040201

Title: Structure and mechanism of mRNA cap (guanine-N7) methyltransferase.

Journal: Molecular cell 20040116

Title: Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells.

Journal: Chemico-biological interactions 20040115

Title: A mathematical model of the methionine cycle.

Journal: Journal of theoretical biology 20040107

Title: Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzyme.

Journal: Science (New York, N.Y.) 20040102

Title: A randomised controlled trial of ursodeoxycholic acid and S-adenosyl-l-methionine in the treatment of gestational cholestasis.

Journal: BJOG : an international journal of obstetrics and gynaecology 20040101

Title: Joint-supplement quality improving.

Journal: Health news (Waltham, Mass.) 20040101

Title: L-deaza-5'-noraisteromycin.

Journal: Nucleosides, nucleotides & nucleic acids 20040101

Title: S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495].

Journal: BMC musculoskeletal disorders 20040101

Title: [Efficacy of combined use of ursodeoxycholic acid and heptral in the treatment of primary biliary cirrhosis].

Journal: Klinicheskaia meditsina 20040101

Title: [Efficacy of combined administration of ursodeoxycholic acid and hepthral in the treatment of primary biliary cirrhosis].

Journal: Klinicheskaia meditsina 20040101

Title: Mutational analysis of basic residues in the N-terminus of the rRNA:m6A methyltransferase ErmC'.

Journal: Folia microbiologica 20040101

Title: Protein methylation activates reconstituted ryanodine receptor-ca release channels from coronary artery myocytes.

Journal: Journal of vascular research 20040101

Title: Techniques in protein methylation.

Journal: Methods in molecular biology (Clifton, N.J.) 20040101

Title: Selected integrative medicine treatments for depression: considerations for women.

Journal: Journal of the American Medical Women's Association (1972) 20040101

Title: S-adenosylhomocysteine hydrolase, S-adenosylmethionine, S-adenosylhomocysteine: correlations with ribavirin induced anemia.

Journal: Medical hypotheses 20040101

Title: S-adenosylmethionine (SAM-e) for the treatment of depression in people living with HIV/AIDS.

Journal: BMC psychiatry 20040101

Title: Methylation demand and homocysteine metabolism.

Journal: Advances in enzyme regulation 20040101

Title: [Correction by 2-ethyl-6-methyl-3-hydroxypyridine succinate of the hepatotoxyc, caused at rats introduction tuberculostatics].

Journal: Biomeditsinskaia khimiia 20040101

Title: Dietary supplementation with 3-deaza adenosine, N-acetyl cysteine, and S-adenosyl methionine provide neuroprotection against multiple consequences of vitamin deficiency and oxidative challenge: relevance to age-related neurodegeneration.

Journal: Neuromolecular medicine 20040101

Title: Effect of naturally occurring mutations in human glycine N-methyltransferase on activity and conformation.

Journal: Biochemical and biophysical research communications 20031226

Title: Methyl deficiency causes reduction of the methyl-CpG-binding protein, MeCP2, in rat liver.

Journal: Carcinogenesis 20031201

Title: Identification of the 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase required for coenzyme F(420) biosynthesis.

Journal: Archives of microbiology 20031201

Title: S-adenosyl-methionine in depression: a comprehensive review of the literature.

Journal: Current psychiatry reports 20031201

Title: RXRalpha-regulated liver SAMe and GSH levels influence susceptibility to alcohol-induced hepatotoxicity.

Journal: Experimental and molecular pathology 20031201

Title: Regulation of methylbenzoate emission after pollination in snapdragon and petunia flowers.

Journal: The Plant cell 20031201

Title: Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes.

Journal: The EMBO journal 20031201

Title: Inhibition mechanism of S-adenosylmethionine-induced movement deficits by prenylcysteine analogs.

Journal: Pharmacology, biochemistry, and behavior 20031201

Title: Involvement of gene-diet/drug interaction in DNA methylation and its contribution to complex diseases: from cancer to schizophrenia.

Journal: Clinical genetics 20031201

Title: Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice.

Journal: Toxicology letters 20031130

Title: Site-specific observation of acyl intermediate processing in thiotemplate biosynthesis by fourier transform mass spectrometry: the polyketide module of yersiniabactin synthetase.

Journal: Biochemistry 20031125

Title: Identification and functional reconstitution of yeast mitochondrial carrier for S-adenosylmethionine.

Journal: The EMBO journal 20031117

Title: Effect of salt stress on the metabolism of ethanolamine and choline in leaves of the betaine-producing mangrove species Avicennia marina.

Journal: Phytochemistry 20031101

Title: Are SAMe and 5-HTP safe and effective treatments for depression?

Journal: Journal of psychiatry & neuroscience : JPN 20031101

Title: Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae.

Journal: The Journal of biological chemistry 20031031

Title: The mechanism of 7,8-diaminopelargonate synthase; the role of S-adenosylmethionine as the amino donor.

Journal: Organic & biomolecular chemistry 20031021

Title: S-adenosyl methionine prevents promiscuous DNA cleavage by the EcoP1I type III restriction enzyme.

Journal: Journal of molecular biology 20031017

Title: S-adenosyl-L-methionine: effects on brain bioenergetic status and transverse relaxation time in healthy subjects.

Journal: Biological psychiatry 20031015

Title: Coordination and mechanism of reversible cleavage of S-adenosylmethionine by the [4Fe-4S] center in lysine 2,3-aminomutase.

Journal: Journal of the American Chemical Society 20031001

Title: S-adenosylmethionine (SAMe) protects against acute alcohol induced hepatotoxicity in mice.

Journal: The Journal of nutritional biochemistry 20031001

Title: Avoiding the road less traveled: how the topology of enzyme-substrate complexes can dictate product selection.

Journal: Accounts of chemical research 20031001

Title: Melithiazol biosynthesis: further insights into myxobacterial PKS/NRPS systems and evidence for a new subclass of methyl transferases.

Journal: Chemistry & biology 20031001

Title: Molecular dissection of the S-adenosylmethionine-binding site of phosphatidylethanolamine N-methyltransferase.

Journal: The Journal of biological chemistry 20030912

Title: Biosynthesis of phytosterols. Kinetic mechanism for the enzymatic C-methylation of sterols.

Journal: The Journal of biological chemistry 20030905

Title: Beta-peltatin 6-O-methyltransferase from suspension cultures of Linum nodiflorum.

Journal: Phytochemistry 20030901

Title: Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation.

Journal: The Journal of biological chemistry 20030808

Title: Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism.

Journal: Journal of molecular biology 20030808

Title: High-performance liquid chromatography determination of methionine adenosyltransferase activity using catechol-O-methyltransferase-coupled fluorometric detection.

Journal: Analytical biochemistry 20030801

Title: L-DOPA biotransformation: correlations of dosage, erythrocyte catechol O-methyltransferase and platelet SULT1A3 activities with metabolic pathways in Parkinsonian patients.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20030801

Title: Plasma homocysteine and S-adenosylmethionine in erythrocytes as determinants of carotid intima-media thickness: different effects in diabetic and non-diabetic individuals. The Hoorn Study.

Journal: Atherosclerosis 20030801

Title: S-adenosyl-L-methionine is able to reverse micronucleus formation induced by sodium arsenite and other cytoskeleton disrupting agents in cultured human cells.

Journal: Mutation research 20030725

Title: Catalytic mechanism of glycine N-methyltransferase.

Journal: Biochemistry 20030722

Title: Isolation and characterisation of 5'-fluorodeoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya.

Journal: FEBS letters 20030717

Title: Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes.

Journal: The Biochemical journal 20030715

Title: Conformational dynamics of the active site loop of S-adenosylmethionine synthetase illuminated by site-directed spin labeling.

Journal: Archives of biochemistry and biophysics 20030715

Title: Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain.

Journal: Protein science : a publication of the Protein Society 20030701

Title: Structural studies of the interaction of S-adenosylmethionine with the [4Fe-4S] clusters in biotin synthase and pyruvate formate-lyase activating enzyme.

Journal: Protein science : a publication of the Protein Society 20030701

Title: Synthetic decarboxylated S-adenosyl-L-methionine as a substrate for aminopropyl transferases.

Journal: Biological & pharmaceutical bulletin 20030701

Title: Hepatic preconditioning after prolonged warm ischemia by means of S-adenosyl-L-methionine administration in pig liver transplantation from non-heart-beating donors.

Journal: Transplantation 20030627

Title: The methyl donor S-Adenosylmethionine inhibits active demethylation of DNA: a candidate novel mechanism for the pharmacological effects of S-Adenosylmethionine.

Journal: The Journal of biological chemistry 20030606

Title: Crystal structure of tRNA(m1G37)methyltransferase: insights into tRNA recognition.

Journal: The EMBO journal 20030602

Title: A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice.

Journal: Cancer chemotherapy and pharmacology 20030601

Title: S-adenosylmethionine (AdoMet) modulates endotoxin stimulated interleukin-10 production in monocytes.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030601

Title: Adenosyl coenzyme and pH dependence of the [4Fe-4S]2+/1+ transition in lysine 2,3-aminomutase.

Journal: Archives of biochemistry and biophysics 20030601

Title: L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionine.

Journal: The Journal of biological chemistry 20030530

Title: Crystal structure of the avilamycin resistance-conferring methyltransferase AviRa from Streptomyces viridochromogenes.

Journal: Journal of molecular biology 20030523

Title: Kinetic mechanism of the tRNA-modifying enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA).

Journal: Biochemistry 20030513

Title: Efficiency of lignin biosynthesis: a quantitative analysis.

Journal: Annals of botany 20030501

Title: Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice.

Journal: Biochemical pharmacology 20030501

Title: Altered methionine metabolism in long living Ames dwarf mice.

Journal: Experimental gerontology 20030501

Title: Presenilin 1 gene silencing by S-adenosylmethionine: a treatment for Alzheimer disease?

Journal: FEBS letters 20030424

Title: Purification and kinetic characterization of the magnesium protoporphyrin IX methyltransferase from Synechocystis PCC6803.

Journal: The Biochemical journal 20030415

Title: Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism.

Journal: Blood 20030415

Title: Reaction mechanism and regulation of cystathionine beta-synthase.

Journal: Biochimica et biophysica acta 20030411

Title: S-adenosylmethionine (SAMe) in a feline acetaminophen model of oxidative injury.

Journal: Journal of feline medicine and surgery 20030401

Title: Insertional inactivation of the methionine s-methyltransferase gene eliminates the s-methylmethionine cycle and increases the methylation ratio.

Journal: Plant physiology 20030401

Title: Simultaneous detection of S-adenosylmethionine and S-adenosylhomocysteine in mouse and rat tissues by capillary electrophoresis.

Journal: Electrophoresis 20030401

Title: The generation of 5'-deoxyadenosyl radicals by adenosylmethionine-dependent radical enzymes.

Journal: Current opinion in chemical biology 20030401

Title: Increased response of liver microsomal delta 6-desaturase activity to dietary methionine in rats.

Journal: Bioscience, biotechnology, and biochemistry 20030401

Title: Isolation and characterization of 27-O-demethylrifamycin SV methyltransferase provides new insights into the post-PKS modification steps during the biosynthesis of the antitubercular drug rifamycin B by Amycolatopsis mediterranei S699.

Journal: Archives of biochemistry and biophysics 20030315

Title: Control of adenosylmethionine-dependent radical generation in biotin synthase: a kinetic and thermodynamic analysis of substrate binding to active and inactive forms of BioB.

Journal: Biochemistry 20030311

Title: A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3.

Journal: Nature structural biology 20030301

Title: [Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].

Journal: Pathologie-biologie 20030301

Title: Effects of S-adenosylmethionine on hepatic regeneration after partial hepatectomy in the rat.

Journal: Journal of physiology and biochemistry 20030301

Title: Dose-dependent biotransformation of arsenite in rats--not S-adenosylmethionine depletion impairs arsenic methylation at high dose.

Journal: Toxicology 20030201

Title: [Enhancement of the production of SAM by overexpression of SAM synthetase in Pichia pastoris].

Journal: Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20030201

Title: Functional analysis of BamHI DNA cytosine-N4 methyltransferase.

Journal: Journal of molecular biology 20030124

Title: Kinetic inhibitory profile of BIA 3-202, a novel fast tight-binding, reversible and competitive catechol-O-methyltransferase inhibitor.

Journal: European journal of pharmacology 20030124

Title: Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet.

Journal: The EMBO journal 20030115

Title: Assay for the enantiomeric analysis of [2H1]-fluoroacetic acid: insight into the stereochemical course of fluorination during fluorometabolite biosynthesis in streptomyces cattleya.

Journal: Journal of the American Chemical Society 20030115

Title: Alternative therapies for traditional disease states: osteoarthritis.

Journal: American family physician 20030115

Title: Mapping and molecular modeling of S-adenosyl-L-methionine binding sites in N-methyltransferase domains of the multifunctional polypeptide cyclosporin synthetase.

Journal: The Journal of biological chemistry 20030110

Title: Catechol-O-methyltransferase inhibition protects against 3,4-dihydroxyphenylalanine (DOPA) toxicity in primary mesencephalic cultures: new insights into levodopa toxicity.

Journal: Neurochemistry international 20030101

Title: Role of S-adenosylmethionine in two experimental models of pancreatitis.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030101

Title: S-adenosylhomocysteine and the ratio of S-adenosylmethionine to S-adenosylhomocysteine are not related to folate, cobalamin and vitamin B6 concentrations.

Journal: European journal of clinical investigation 20030101

Title: Leishmania donovani methionine adenosyltransferase. Role of cysteine residues in the recombinant enzyme.

Journal: European journal of biochemistry 20030101

Title: Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice.

Journal: Carcinogenesis 20030101

Title: The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon.

Journal: Carcinogenesis 20030101

Title: [DNA-[N4-cytosine]-methyltransferase from Bacillus amyloliquefaciens: mechanism of action derived from steady state kinetics].

Journal: Molekuliarnaia biologiia 20030101

Title: Characterization of the cofactor-binding site in the SPOUT-fold methyltransferases by computational docking of S-adenosylmethionine to three crystal structures.

Journal: BMC bioinformatics 20030101

Title: Polyenylphosphatidylcholine corrects the alcohol-induced hepatic oxidative stress by restoring s-adenosylmethionine.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20030101

Title: Alternative treatment modalities in human immunodeficiency virus/acquired immune deficiency syndrome.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030101

Title: A novel function for the rTS gene.

Journal: Cancer biology & therapy 20030101

Title: Differential transcriptional regulation of two distinct S-adenosylmethionine synthetase genes (SAM1 and SAM2) of Saccharomyces cerevisiae.

Journal: Nucleic acids research. Supplement (2001) 20030101

Title: Homocystinuria due to cystathionine beta-synthase deficiency: novel biochemical findings and treatment efficacy.

Journal: Journal of inherited metabolic disease 20030101

Title: S-adenosylmethionine (AdoMet) supplementation for treatment of chemotherapy-induced liver injury.

Journal: Anticancer research 20030101

Title: Incorporating mechanistic data into risk assessment.

Journal: Toxicology 20021227

Title: Deletion mutagenesis of human cystathionine beta-synthase. Impact on activity, oligomeric status, and S-adenosylmethionine regulation.

Journal: The Journal of biological chemistry 20021213

Title: Osteoarthritis. Options for arthritis pain.

Journal: Newsweek 20021202

Title: Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage.

Journal: Journal of neuroscience research 20021201

Title: A double-blind, randomized parallel-group, efficacy and safety study of intramuscular S-adenosyl-L-methionine 1,4-butanedisulphonate (SAMe) versus imipramine in patients with major depressive disorder.

Journal: The international journal of neuropsychopharmacology 20021201

Title: Pharmacodynamic studies on the central mode of action of S-adenosyl-L-methionine (SAMe) infusions in elderly subjects, utilizing EEG mapping and psychometry.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20021201

Title: Structural basis of ICF-causing mutations in the methyltransferase domain of DNMT3B.

Journal: Protein engineering 20021201

Title: Anthocyanin administration elevates plasma homocysteine in rats.

Journal: Journal of nutritional science and vitaminology 20021201

Title: The [4Fe-4S](2+) cluster in reconstituted biotin synthase binds S-adenosyl-L-methionine.

Journal: Journal of the American Chemical Society 20021127

Title: S-homoadenosyl-L-cysteine and S-homoadenosyl-L-homocysteine. Synthesis and binding studies of hon-hydrolyzed substrate analogues with S-adenosyl-L-homocysteine hydrolase.

Journal: The Journal of organic chemistry 20021115

Title: Stabilization of S-adenosyl-L-methionine promoted by trehalose.

Journal: Biochimica et biophysica acta 20021114

Title: Remethylation and transsulfuration of methionine in cirrhosis: studies with L-[H3-methyl-1-C]methionine.

Journal: Hepatology (Baltimore, Md.) 20021101

Title: [Meta-analysis of the efficacy of adenosylmethionine and oxaceprol in the treatment of osteoarthritis].

Journal: Der Orthopade 20021101

Title: The dual-specific active site of 7,8-diaminopelargonic acid synthase and the effect of the R391A mutation.

Journal: Biochemistry 20021022

Title: Novel S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme responsible for biosynthesis of methyl salicylate and methyl benzoate, is not involved in floral scent production in snapdragon flowers.

Journal: Archives of biochemistry and biophysics 20021015

Title: Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses.

Journal: The Journal of biological chemistry 20021011

Title: Alleviation of intrasteric inhibition by the pathogenic activation domain mutation, D444N, in human cystathionine beta-synthase.

Journal: Biochemistry 20021001

Title: The production of hydrogen sulfide is regulated by testosterone and S-adenosyl-L-methionine in mouse brain.

Journal: Journal of neurochemistry 20021001

Title: Biosynthetic studies on the tropane alkaloid hyoscyamine in Datura stramonium; hyoscyamine is stable to in vivo oxidation and is not derived from littorine via a vicinal interchange process.

Journal: Phytochemistry 20021001

Title: Characterization of human soluble high and low activity catechol-O-methyltransferase catalyzed catechol estrogen methylation.

Journal: Pharmacogenetics 20021001

Title: An essential role of s-adenosyl-L-methionine:L-methionine s-methyltransferase in selenium volatilization by plants. Methylation of selenomethionine to selenium-methyl-L-selenium- methionine, the precursor of volatile selenium.

Journal: Plant physiology 20021001

Title: An anchoring role for FeS clusters: chelation of the amino acid moiety of S-adenosylmethionine to the unique iron site of the [4Fe-4S] cluster of pyruvate formate-lyase activating enzyme.

Journal: Journal of the American Chemical Society 20020925

Title: A stereospecific colorimetric assay for (S,S)-adenosylmethionine quantification based on thiopurine methyltransferase-catalyzed thiol methylation.

Journal: Analytical biochemistry 20020915

Title: Visualizing central effects of S-adenosyl-L-methionine (SAMe), a natural molecule with antidepressant properties, by pharmaco-EEG mapping.

Journal: The international journal of neuropsychopharmacology 20020901

Title: S-adenosyl-methionine-induced apoptosis in PC12 cells.

Journal: Journal of neuroscience research 20020815

Title: Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha.

Journal: The Journal of biological chemistry 20020809

Title: Altered levels of S-adenosylmethionine and S-adenosylhomocysteine in the brains of L-isoaspartyl (D-Aspartyl) O-methyltransferase-deficient mice.

Journal: The Journal of biological chemistry 20020802

Title: Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020801

Title: Quantification of plasma S-adenosylmethionine and S-adenosylhomocysteine as their fluorescent 1,N(6)-etheno derivatives: an adaptation of previously described methodology.

Journal: Journal of pharmaceutical and biomedical analysis 20020731

Title: Cystathionine beta-synthase is coordinately regulated with proliferation through a redox-sensitive mechanism in cultured human cells and Saccharomyces cerevisiae.

Journal: Journal of cellular physiology 20020701

Title: Role of S-adenosyl-L-methionine in the treatment of alcoholic liver disease: introduction and summary of the symposium.

Journal: Alcohol (Fayetteville, N.Y.) 20020701

Title: Role of abnormal methionine metabolism in alcoholic liver injury.

Journal: Alcohol (Fayetteville, N.Y.) 20020701

Title: S-Adenosylmethionine revisited: its essential role in the regulation of liver function.

Journal: Alcohol (Fayetteville, N.Y.) 20020701

Title: S-Adenosyl-L-methionine and alcoholic liver disease in animal models: implications for early intervention in human beings.

Journal: Alcohol (Fayetteville, N.Y.) 20020701

Title: S-Adenosyl-L-methionine and mitochondrial reduced glutathione depletion in alcoholic liver disease.

Journal: Alcohol (Fayetteville, N.Y.) 20020701

Title: S-Adenosylmethionine, cytokines, and alcoholic liver disease.

Journal: Alcohol (Fayetteville, N.Y.) 20020701

Title: Chemoprevention of hepatocarcinogenesis: S-adenosyl-L-methionine.

Journal: Alcohol (Fayetteville, N.Y.) 20020701

Title: S-adenosylmethionine is substrate for carrier mediated transport at the blood-brain barrier in vitro.

Journal: Brain research 20020628

Title: S-adenosylmethionine conformations in solution and in protein complexes: conformational influences of the sulfonium group.

Journal: Biochemistry 20020618

Title: High homocysteine and thrombosis without connective tissue disorders are associated with a novel class of cystathionine beta-synthase (CBS) mutations.

Journal: Human mutation 20020601

Title: The effect of troglitazone on plasma homocysteine, hepatic and red blood cell S-adenosyl methionine, and S-adenosyl homocysteine and enzymes in homocysteine metabolism in Zucker rats.

Journal: Metabolism: clinical and experimental 20020601

Title: Expression of recombinant human betaine: homocysteine S-methyltransferase for x-ray crystallographic studies and further characterization of interaction with S-adenosylmethionine.

Journal: Protein expression and purification 20020601

Title: Probing the mysteries of lignin biosynthesis: the crystal structure of caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase provides new insights.

Journal: The Plant cell 20020601

Title: Recombinant alpha and beta subunits of M.AquI constitute an active DNA methyltransferase.

Journal: Journal of biochemistry and molecular biology 20020531

Title: Brain hydrogen sulfide is severely decreased in Alzheimer's disease.

Journal: Biochemical and biophysical research communications 20020524

Title: 3-O-methyldobutamine, a major metabolite of dobutamine in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020501

Title: Diethanolamine induces hepatic choline deficiency in mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020501

Title: NO sensitizes rat hepatocytes to proliferation by modifying S-adenosylmethionine levels.

Journal: Gastroenterology 20020501

Title: The Pneumocystis carinii drug target S-adenosyl-L-methionine:sterol C-24 methyl transferase has a unique substrate preference.

Journal: Molecular microbiology 20020501

Title: Activation and induction of glycine N-methyltransferase by retinoids are tissue- and gender-specific.

Journal: Archives of biochemistry and biophysics 20020501

Title: [Production of SAM by recombinant Pichia pastoris].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20020501

Title: Reductive cleavage of S-adenosylmethionine by biotin synthase from Escherichia coli.

Journal: The Journal of biological chemistry 20020419

Title: Enzymatic synthesis of [3'-O-methyl-(3)H]malvidin-3-glucoside from petunidin-3-glucoside.

Journal: Journal of agricultural and food chemistry 20020410

Title: Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop.

Journal: The EMBO journal 20020402

Title: LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone.

Journal: Microbiology (Reading, England) 20020401

Title: Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus.

Journal: Molecular cell 20020401

Title: L-Homoserine: a novel excreted metabolic marker of hepatitis B abnormally produced in liver from methionine.

Journal: Medical hypotheses 20020401

Title: S-adenosylhomocysteine, but not homocysteine, is toxic to yeast lacking cystathionine beta-synthase.

Journal: Molecular genetics and metabolism 20020401

Title: Direct H atom abstraction from spore photoproduct C-6 initiates DNA repair in the reaction catalyzed by spore photoproduct lyase: evidence for a reversibly generated adenosyl radical intermediate.

Journal: Journal of the American Chemical Society 20020327

Title: Electron-nuclear double resonance spectroscopic evidence that S-adenosylmethionine binds in contact with the catalytically active [4Fe-4S](+) cluster of pyruvate formate-lyase activating enzyme.

Journal: Journal of the American Chemical Society 20020327

Title: Biochemistry: biosynthesis of an organofluorine molecule.

Journal: Nature 20020321

Title: S-adenosyl-L-methionine prevents 5-HT(1A) receptors up-regulation induced by acute imipramine in the frontal cortex of the rat.

Journal: Neuroscience letters 20020315

Title: Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy.

Journal: Neurology 20020312

Title: Adenosine kinase deficiency is associated with developmental abnormalities and reduced transmethylation.

Journal: Plant physiology 20020301

Title: Studies on the role of the metK gene product of Escherichia coli K-12.

Journal: Molecular microbiology 20020301

Title: Tissue levels of S-adenosylhomocysteine in the rat kidney: effects of ischemia and homocysteine.

Journal: Biochemical pharmacology 20020215

Title: Coordination of adenosylmethionine to a unique iron site of the [4Fe-4S] of pyruvate formate-lyase activating enzyme: a Mössbauer spectroscopic study.

Journal: Journal of the American Chemical Society 20020213

Title: Metabolic engineering in yeast demonstrates that S-adenosylmethionine controls flux through the methylenetetrahydrofolate reductase reaction in vivo.

Journal: The Journal of biological chemistry 20020208

Title: S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

Journal: Hepatology (Baltimore, Md.) 20020201

Title: The N-terminal region of Arabidopsis cystathionine gamma-synthase plays an important regulatory role in methionine metabolism.

Journal: Plant physiology 20020201

Title: High free-methionine and decreased lignin content result from a mutation in the Arabidopsis S-adenosyl-L-methionine synthetase 3 gene.

Journal: The Plant journal : for cell and molecular biology 20020201

Title: An in vitro screening method for DNA cytosine-C5-methylase inhibitor.

Journal: Natural product letters 20020201

Title: S-adenosylmethionine in treatment of cholestasis after total parenteral nutrition: laboratory investigation and clinical application.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20020201

Title: Effects of S-adenosyl-L-methionine on lipid peroxidation and glutathione levels in rat brain slices exposed to reoxygenation after oxygen-glucose deprivation.

Journal: Neuroscience letters 20020125

Title: Clinical nutrition: 3. The fuzzy boundary between nutrition and psychopharmacology.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20020122

Title: Obstetric cholestasis: outcome with active management.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20020110

Title: Molecular cloning and characterization of coclaurine N-methyltransferase from cultured cells of Coptis japonica.

Journal: The Journal of biological chemistry 20020104

Title: Bacteriophage T4 Dam DNA-[N6-adenine]methyltransferase. Kinetic evidence for a catalytically essential conformational change in the ternary complex.

Journal: The Journal of biological chemistry 20020104

Title: Domain alternation switches B(12)-dependent methionine synthase to the activation conformation.

Journal: Nature structural biology 20020101

Title: Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice.

Journal: Carcinogenesis 20020101

Title: S-Adenosylmethionine: a control switch that regulates liver function.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020101

Title: Constitutive overexpression of cystathionine gamma-synthase in Arabidopsis leads to accumulation of soluble methionine and S-methylmethionine.

Journal: Plant physiology 20020101

Title: S-adenosyl-L-methionine (SAMe) for the treatment of acetaminophen toxicity in a dog.

Journal: Journal of the American Animal Hospital Association 20020101

Title: [Metabolism pathways and use of heptral in chronic liver diseases].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20020101

Title: [Aging of the pineal gland].

Journal: Advances in gerontology = Uspekhi gerontologii 20020101

Title: Liquid chromatographic determination of S-adenosyl-L-methionine in dietary supplement tablets.

Journal: Journal of AOAC International 20020101

Title: [Isolation of S-adenosyl-L-methionine from an enriched Kluyveromyces lactis mutant, grown in whey media].

Journal: Prikladnaia biokhimiia i mikrobiologiia 20020101

Title: [Use of heptral in the complex treatment of pregnant women with cholestatic liver disease].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20020101

Title: [The kinetic mechanism of phage T4 DNA-[N6-adenine]-methyltransferase].

Journal: Molekuliarnaia biologiia 20020101

Title: Scavengers protection of cells against ALA-based photodynamic therapy-induced damage.

Journal: Lasers in medical science 20020101

Title: Kinetic characterization of transient free radical intermediates in reaction of lysine 2,3-aminomutase by EPR lineshape analysis.

Journal: Methods in enzymology 20020101

Title: Structure, catalytic activity and evolutionary relationships of 1-aminocyclopropane-1-carboxylate synthase, the key enzyme of ethylene synthesis in higher plants.

Journal: Acta biochimica Polonica 20020101

Title: S-adenosylmethionine and cAMP confer differential cytoprotection against bile acid-induced apoptosis in canine renal tubular cells and primary rat hepatocytes.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20020101

Title: Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii.

Journal: Journal of structural and functional genomics 20020101

Title: Influence of SAMe on the modifications of brain polyamine levels in an animal model of depression.

Journal: Neuroreport 20011221

Title: Impact of extracellular folate levels on global gene expression.

Journal: Molecular pharmacology 20011201

Title: The effect of high doses of folic acid on the overexpression of ornithine decarboxylase and S-adenosylmethionine content in human colon adenomatous polyps.

Journal: Annals of the New York Academy of Sciences 20011201

Title: Design of allele-specific protein methyltransferase inhibitors.

Journal: Journal of the American Chemical Society 20011128

Title: Characterization of AloI, a restriction-modification system of a new type.

Journal: Journal of molecular biology 20011123

Title: Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate.

Journal: Journal of molecular biology 20011109

Title: S-adenosyl-L-methionine N-ole-1-oyltaurate: pharmacokinetic of the orally administered salt in rats.

Journal: International journal of pharmaceutics 20011106

Title: Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20011101

Title: Anti-aging products, Part I. Can supplements rewind our body clocks?

Journal: Harvard women's health watch 20011101

Title: Glutamate 47 in 1-aminocyclopropane-1-carboxylate synthase is a major specificity determinant.

Journal: Biochemistry 20011016

Title: Reversed-phase high-performance liquid chromatography procedure for the simultaneous determination of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine in mouse liver and the effect of methionine on their concentrations.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20011005

Title: Methylation is involved in the Ustilago maydis mating response.

Journal: Fungal genetics and biology : FG & B 20011001

Title: COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.

Journal: Carcinogenesis 20011001

Title: Adenosylmethionine as a source of 5'-deoxyadenosyl radicals.

Journal: Current opinion in chemical biology 20011001

Title: Enzymology of carbon-sulfur bond formation.

Journal: Current opinion in chemical biology 20011001

Title: Getting the adrenaline going: crystal structure of the adrenaline-synthesizing enzyme PNMT.

Journal: Structure (London, England : 1993) 20011001

Title: Determination of thiopurine methyltransferase activity in human erythrocytes by high-performance liquid chromatography: comparison with the radiochemical method.

Journal: Therapeutic drug monitoring 20011001

Title: Nutritional regulation of homocysteine: effects of drugs.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20011001

Title: DNA cleavage by type III restriction-modification enzyme EcoP15I is independent of spacer distance between two head to head oriented recognition sites.

Journal: Journal of molecular biology 20010928

Title: Regulation of human cystathionine beta-synthase by S-adenosyl-L-methionine: evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region.

Journal: Biochemistry 20010904

Title: Increasing levels of dietary homocystine with carotid endarterectomy produced proportionate increases in plasma homocysteine and intimal hyperplasia.

Journal: Atherosclerosis 20010901

Title: L-dopa upregulates the expression and activities of methionine adenosyl transferase and catechol-O-methyltransferase.

Journal: Experimental neurology 20010901

Title: Blood S-adenosylmethionine concentrations and lymphocyte methylenetetrahydrofolate reductase activity in diabetes mellitus and diabetic nephropathy.

Journal: Metabolism: clinical and experimental 20010901

Title: Effects of S-adenosyl-L-methionine on liver damage in experimental obstructive jaundice.

Journal: The Kaohsiung journal of medical sciences 20010901

Title: PRMT5 (Janus kinase-binding protein 1) catalyzes the formation of symmetric dimethylarginine residues in proteins.

Journal: The Journal of biological chemistry 20010831

Title: Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor.

Journal: Science (New York, N.Y.) 20010803

Title: Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia.

Journal: Journal of inherited metabolic disease 20010801

Title: Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease.

Journal: Neuroscience letters 20010727

Title: Characterization of an allylic analogue of the 5'-deoxyadenosyl radical: an intermediate in the reaction of lysine 2,3-aminomutase.

Journal: Biochemistry 20010703

Title: Diadenosine phosphates and S-adenosylmethionine: novel boron binding biomolecules detected by capillary electrophoresis.

Journal: Biochimica et biophysica acta 20010702

Title: Homocysteine metabolism in children with Down syndrome: in vitro modulation.

Journal: American journal of human genetics 20010701

Title: Wy-14,643-induced hypomethylation of the c-myc gene in mouse liver.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010701

Title: Roles of homocysteine in cell metabolism: old and new functions.

Journal: European journal of biochemistry 20010701

Title: The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule.

Journal: Molecular microbiology 20010701

Title: S-adenosyl-L-methionine is required for DNA cleavage by type III restriction enzymes.

Journal: Journal of molecular biology 20010629

Title: The mechanism of DNA cytosine-5 methylation. Kinetic and mutational dissection of Hhai methyltransferase.

Journal: The Journal of biological chemistry 20010615

Title: A new caffeine biosynthetic pathway in tea leaves: utilisation of adenosine released from the S-adenosyl-L-methionine cycle.

Journal: FEBS letters 20010615

Title: Activation of class III ribonucleotide reductase from E. coli. The electron transfer from the iron-sulfur center to S-adenosylmethionine.

Journal: Biochemistry 20010612

Title: Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.

Journal: Circulation research 20010608

Title: Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: correlations with diet.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010601

Title: Effect of vitamin B6 deficiency on the synthesis and accumulation of S-adenosylhomocysteine and S-adenosylmethionine in rat tissues.

Journal: Journal of nutritional science and vitaminology 20010601

Title: Inhibition of liver methionine adenosyltransferase gene expression by 3-methylcolanthrene: protective effect of S-adenosylmethionine.

Journal: Biochemical pharmacology 20010501

Title: Impaired homocysteine metabolism and atherothrombotic disease.

Journal: Laboratory investigation; a journal of technical methods and pathology 20010501

Title: How is the liver primed or sensitized for alcoholic liver disease?

Journal: Alcoholism, clinical and experimental research 20010501

Title: Ca2+-antagonists inhibit the N-methyltransferase-dependent synthesis of phosphatidylcholine in the heart.

Journal: Molecular and cellular biochemistry 20010501

Title: Metabolic labeling of prenyl and carboxyl-methyl groups.

Journal: Current protocols in cell biology 20010501

Title: S-Adenosyl-L-methionine-dependent O-methylation of 2-hydroxy-3-alkylpyrazine in wine grapes: a putative final step of methoxypyrazine biosynthesis.

Journal: Bioscience, biotechnology, and biochemistry 20010401

Title: Activation of class III ribonucleotide reductase by thioredoxin.

Journal: The Journal of biological chemistry 20010330

Title: Activation of class III ribonucleotide reductase by flavodoxin: a protein radical-driven electron transfer to the iron-sulfur center.

Journal: Biochemistry 20010327

Title: Role of adenosine kinase in Saccharomyces cerevisiae: identification of the ADO1 gene and study of the mutant phenotypes.

Journal: Yeast (Chichester, England) 20010315

Title: The dynamics of myogenin site-specific demethylation is strongly correlated with its expression and with muscle differentiation.

Journal: The Journal of biological chemistry 20010309

Title: COMT-dependent protection of dopaminergic neurons by methionine, dimethionine and S-adenosylmethionine (SAM) against L-dopa toxicity in vitro.

Journal: Brain research 20010302

Title: Novel methylated triterpenoids of the gammacerane series from the nitrogen-fixing bacterium Bradyrhizobium japonicum USDA 110.

Journal: European journal of biochemistry 20010301

Title: Adenosylmethionine-dependent iron-sulfur enzymes: versatile clusters in a radical new role.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20010301

Title: 5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication.

Journal: Journal of hepatology 20010301

Title: S-adenosylmethionine protects post-ischemic mitochondrial injury in rat liver.

Journal: Journal of hepatology 20010301

Title: Crystal structure of threonine synthase from Arabidopsis thaliana.

Journal: Protein science : a publication of the Protein Society 20010301

Title: A Taq attack displaces bases.

Journal: Nature structural biology 20010201

Title: Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog.

Journal: Nature structural biology 20010201

Title: Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010201

Title: Effect of tauroursodeoxycholate and S-adenosyl-L-methionine on 17beta-estradiol glucuronide-induced cholestasis.

Journal: Journal of hepatology 20010201

Title: Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010101

Title: Disturbed ratio of erythrocyte and plasma S-adenosylmethionine/S-adenosylhomocysteine in peripheral arterial occlusive disease.

Journal: Atherosclerosis 20010101

Title: Synthesis and characterization of an immobilized phenylethanolamine N-methyltransferase liquid chromatographic stationary phase.

Journal: Analytical biochemistry 20010101

Title: Erythroid differentiation and regulatory gene expression are modulated by adenosine derivatives interfering with S-adenosylmethionine metabolic pathway.

Journal: Journal of cellular biochemistry 20010101

Title: Role of S-adenosyl-L-methionine in potentiating cadmium mobilization by diethylenetriamine penta acetic acid in mice.

Journal: Cytobios 20010101

Title: Liver diseases by alcohol and hepatitis C: early detection and new insights in pathogenesis lead to improved treatment.

Journal: The American journal on addictions 20010101

Title: Radical mechanisms of enzymatic catalysis.

Journal: Annual review of biochemistry 20010101

Title: Radical mechanisms of S-adenosylmethionine-dependent enzymes.

Journal: Advances in protein chemistry 20010101

Title: Interventions for treating cholestasis in pregnancy.

Journal: The Cochrane database of systematic reviews 20010101

Title: S-adenosyl-L-methionine for alcoholic liver diseases.

Journal: The Cochrane database of systematic reviews 20010101

Title: The role of radicals in enzymatic processes.

Journal: Chemical record (New York, N.Y.) 20010101

Title: Escherichia coli LipA is a lipoyl synthase: in vitro biosynthesis of lipoylated pyruvate dehydrogenase complex from octanoyl-acyl carrier protein.

Journal: Biochemistry 20001212

Title: Effect of different doses of S-adenosyl-L-methionine on paracetamol hepatotoxicity in a mouse model.

Journal: Methods and findings in experimental and clinical pharmacology 20001201

Title: Farnesyl-L-cysteine analogs block SAM-induced Parkinson's disease-like symptoms in rats.

Journal: Pharmacology, biochemistry, and behavior 20000801

Title: Homocysteine.

Journal: The international journal of biochemistry & cell biology 20000401

Title: Molecular biology of 5,10-methylenetetrahydrofolate reductase.

Journal: Journal of nephrology 20000101

Title: Open study of the catechol-O-methyltransferase inhibitor tolcapone in major depressive disorder.

Journal: Journal of clinical psychopharmacology 19990801

Title: Differential effect of thioacetamide on hepatic methionine adenosyltransferase expression in the rat.

Journal: Hepatology (Baltimore, Md.) 19990501

Title: One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.

Journal: Journal of inherited metabolic disease 19981201

Title: Purification, characterization, and cloning of an S-adenosylmethionine-dependent 3-amino-3-carboxypropyltransferase in nocardicin biosynthesis.

Journal: The Journal of biological chemistry 19981113

Title: Demyelination and single-carbon transfer pathway metabolites during the treatment of acute lymphoblastic leukemia: CSF studies.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19980401

Title: Effects of some thiol chelators on enzymatic activities in blood, liver and kidneys of acute arsenic (III) exposed mice.

Journal: Biomedical and environmental sciences : BES 19980301

Title: [Morphological changes induced by valproate and its administration concomitant with folinic acid or S-adenosylmethionine in pregnant rats].

Journal: Nutricion hospitalaria 19980101

Title: Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosis.

Journal: Journal of hepatology 19960801

Title: S-Adenosylmethionine and methylation.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19960301

Title: Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide.

Journal: European journal of clinical pharmacology 19960101

Title: Ultrastructural features of danazol-induced cholestasis: a case study.

Journal: Ultrastructural pathology 19960101

Title: Enzymatic methylation of arsenic compounds: assay, partial purification, and properties of arsenite methyltransferase and monomethylarsonic acid methyltransferase of rabbit liver.

Journal: Chemical research in toxicology 19951201

Title: Arrangement of catalytic sites in the multifunctional enzyme enniatin synthetase.

Journal: European journal of biochemistry 19950515

Title: Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme.

Journal: Biochemistry 19950404

Title: The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders.

Journal: Drugs 19940801

Title: Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis.

Journal: Cancer letters 19940429

Title: Adenosylmethionine-dependent synthesis of the glycyl radical in pyruvate formate-lyase by abstraction of the glycine C-2 pro-S hydrogen atom. Studies of [2H]glycine-substituted enzyme and peptides homologous to the glycine 734 site.

Journal: The Journal of biological chemistry 19940429

Title: Differential kinetic properties of L-2-amino-4-methylthio-cis-but-3-enoic acid, a methionine analog inhibitor of S-adenosylmethionine synthetase.

Journal: Biochimica et biophysica acta 19930903

Title: S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson's disease-like symptoms.

Journal: Behavioral and neural biology 19930501

Title: Resolution of danazol-induced cholestasis with S-adenosylmethionine.

Journal: Postgraduate medical journal 19930301

Title: Parkinson's disease-like effects of S-adenosyl-L-methionine: effects of L-dopa.

Journal: Pharmacology, biochemistry, and behavior 19921001

Title: Reversal of extrahepatic membrane cholesterol deposition in patients with chronic liver diseases by S-adenosyl-L-methionine.

Journal: Clinical science (London, England : 1979) 19920901

Title: S-adenosylmethionine: studies on chemical and enzymatic synthesis.

Journal: Biotechnology and applied biochemistry 19870201

Title: Open trial of S-adenosylmethionine for treatment of depression.

Journal: The American journal of psychiatry 19840301

Title: Brain methylation and epileptogenesis: the case of methionine sulfoximine.

Journal: Annals of neurology 19840101

Title: Modulation by S-adenosyl-L-methionine of hepatic Na+,K+-ATPase, membrane fluidity, and bile flow in rats with ethinyl estradiol-induced cholestasis.

Journal: Hepatology (Baltimore, Md.) 19830101

Title: Estrogen-induced cholestasis: clues to pathogenesis and treatment.

Journal: Hepatology (Baltimore, Md.) 19830101

Title: Ethynylestradiol-induced impairment of bile secretion in the rat: protective effects of S-adenosyl-L-methionine and its implication in estrogen metabolism.

Journal: Gastroenterology 19810101

Title: Tremor induced by S-adenosyl-L-methionine: possible relation to L-dopa effects.

Journal: The Journal of pharmacy and pharmacology 19781201

Title: Letter: General base catalysis in nucleophilic attack at sp3 carbon of methylase model compounds.

Journal: Journal of the American Chemical Society 19760218

Title: Methionine metabolism in mammals: synthesis of S-adenosylhomocysteine in rat tissues.

Journal: Archives of biochemistry and biophysics 19731101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:29908-03-0 Molecular Formula|29908-03-0 MDL|29908-03-0 SMILES|29908-03-0 S-Adenosyl-l-methionine