[1]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn46-47
[1]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn46
[2]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn48-49
[3]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn54-55
[4]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[5]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[6]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[7]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[8]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[9]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[10]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[11]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[12]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[13]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[14]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[15]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[16]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[17]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[18]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[19]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[20]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[21]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[22]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[23]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[24]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[25]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[26]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[27]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[28]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[29]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[30]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[31]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[32]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn50-51
[33]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn49-50
[34]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn49-50
[35]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn49-50
[36]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn49-50
[37]Patent:WO2005/77922,2005,A2,.Locationinpatent:Page/Pagecolumn49-50
[1]JournalofMedicinalChemistry,2005,vol.48,#13,p.4208-4211
[2]BioorganicandMedicinalChemistryLetters,2010,vol.20,#24,p.7454-7457
[1]JournalofMedicinalChemistry,2005,vol.48,#13,p.4208-4211
[1]JournalofMedicinalChemistry,2005,vol.48,#13,p.4208-4211
Title: Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders.
Journal: ACS medicinal chemistry letters 20170608
Title: ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20150414
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Journal: The Biochemical journal 20130415
Title: Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases.
Journal: Current cancer drug targets 20120701
Title: Mutants of protein kinase A that mimic the ATP-binding site of Aurora kinase.
Journal: The Biochemical journal 20111115
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111101
Title: Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives.
Journal: European journal of medicinal chemistry 20110601
Title: Diamino-1,2,4-triazole derivatives are selective inhibitors of TYK2 and JAK1 over JAK2 and JAK3.
Journal: Bioorganic & medicinal chemistry letters 20101215
Title: Active and passive tumor targeting of a novel poorly soluble cyclin dependent kinase inhibitor, JNJ-7706621.
Journal: International journal of pharmaceutics 20100615
Title: A quantitative analysis of kinase inhibitor selectivity.
Journal: Nature biotechnology 20080101
Title: Role of the ABCG2 drug transporter in the resistance and oral bioavailability of a potent cyclin-dependent kinase/Aurora kinase inhibitor.
Journal: Molecular cancer therapeutics 20061001
Title: 1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities.
Journal: Journal of medicinal chemistry 20050630
Title: Huang S, et al. Synthesis and evaluation of N-acyl sulfonamides as potential prodrugs of cyclin-dependent kinase inhibitor JNJ-7706621. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3639-41. Epub 2006 May 6.
Title: Matsuhashi A, et al. Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases. Curr Cancer Drug Targets. 2012 Jul;12(6):625-39.
Title: Emanuel S, et al. The in vitro and in vivo effects of JNJ-7706621: a dual inhibitor of cyclin-dependent kinases and aurora kinases. Cancer Res. 2005 Oct 1;65(19):9038-46.
Title: Danhier F, et al. Active and passive tumor targeting of a novel poorly soluble cyclin dependent kinase inhibitor, JNJ-7706621. Int J Pharm. 2010 Jun 15;392(1-2):20-8.