[1]CurrentPatentAssignee:SOCIETECIVILENOUVELLEMARCELLESAFFRE-US2009/209543,2009,A1Locationinpatent:Page/Pagecolumn3
[1]CurrentPatentAssignee:SOCIETECIVILENOUVELLEMARCELLESAFFRE-US2009/209543,2009,A1Locationinpatent:Page/Pagecolumn3
[1]CurrentPatentAssignee:CERBIOSPHARMASA-US2010/168117,2010,A1Locationinpatent:Page/Pagecolumn3
[2]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2013/25203,2013,A1Locationinpatent:Page/Pagecolumn26;27
[3]CurrentPatentAssignee:CERBIOSPHARMASA-US2015/152110,2015,A1Locationinpatent:Paragraph0035;0036
[4]CurrentPatentAssignee:JIANGSUYEWPHARMACEUTICAL-CN108164531,2018,ALocationinpatent:Paragraph0042;0053;0054;0062;0063
[5]CurrentPatentAssignee:LIANYUNGANGGUANXINPHARMACEUTICALTECH-CN113603691,2021,ALocationinpatent:Paragraph0050;0054;0055;0057;0058;0060;0061;0063
[1]CurrentPatentAssignee:CERBIOSPHARMASA-US2010/168117,2010,A1Locationinpatent:Page/Pagecolumn3
[1]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2013/25203,2013,A1
Title: Enhanced oral bioavailability of a novel folate salt: comparison with folic acid and a calcium folate salt in a pharmacokinetic study in rats.
Journal: Minerva ginecologica 20160401
Title: Assessing Effects of l-Methylfolate in Depression Management: Results of a Real-World Patient Experience Trial.
Journal: The primary care companion for CNS disorders 20130101
Title: Investigation of protocols to extraction and quantification of folates in vegetables matrices split into liquor and fiber fraction using factorial design.
Journal: Journal of chromatography. A 20121019
Title: Prevention of lethal murine pancreas ischemia reperfusion injury is specific for tetrahydrobiopterin.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20121001
Title: Study of the pharmacokinetic and pharmacogenetic contribution to the toxicity of high-dose methotrexate in children with acute lymphoblastic leukemia.
Journal: Medical oncology (Northwood, London, England) 20120901
Title: Therapy of hyperhomocysteinemia in hemodialysis patients: effects of folates and N-acetylcysteine.
Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20120901
Title: Augmentation of reduced folate carrier-mediated folate/antifolate transport through an antiport mechanism with 5-aminoimidazole-4-carboxamide riboside monophosphate.
Journal: Molecular pharmacology 20120801
Title: Comprehensive quantitative measurement of folate polyglutamates in human erythrocytes by ion pairing ultra-performance liquid chromatography/tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20120730
Title: Molecular characterization of folate receptor 1 mutations delineates cerebral folate transport deficiency.
Journal: Brain : a journal of neurology 20120701
Title: Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa.
Journal: Cancer prevention research (Philadelphia, Pa.) 20120701
Title: Farletuzumab, an anti-folate receptor α antibody, does not block binding of folate or anti-folates to receptor nor does it alter the potency of anti-folates in vitro.
Journal: Cancer chemotherapy and pharmacology 20120701
Title: Peptide fingerprinting of folate-responsive proteins in human B lymphoblasts and orofacial clefting.
Journal: European journal of clinical investigation 20120701
Title: Assessing the influence of 5,10-methylenetetrahydrofolate reductase polymorphism on folate stability during long-term frozen storage, thawing, and repeated freeze/thawing of whole blood.
Journal: Clinica chimica acta; international journal of clinical chemistry 20120614
Title: Adult-onset cerebral folate deficiency.
Journal: Archives of neurology 20120601
Title: Dietary supplement drug therapies for depression.
Journal: Journal of psychosocial nursing and mental health services 20120601
Title: Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder.
Journal: The Journal of clinical psychiatry 20120601
Title: B vitamin and/or ω-3 fatty acid supplementation and cancer: ancillary findings from the supplementation with folate, vitamins B6 and B12, and/or omega-3 fatty acids (SU.FOL.OM3) randomized trial.
Journal: Archives of internal medicine 20120409
Title: Measurement of folate.
Journal: Journal of clinical pathology 20120401
Title: Epigenetics of colorectal cancer.
Journal: Clinical genetics 20120401
Title: Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid.
Journal: Clinical chemistry and laboratory medicine 20120324
Title: Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis.
Journal: Molecular psychiatry 20120301
Title: Polymorphic variants of genes involved in homocysteine metabolism in celiac disease.
Journal: Molecular biology reports 20120301
Title: Effect of B-vitamins and n-3 PUFA supplementation for 5 years on blood pressure in patients with CVD.
Journal: The British journal of nutrition 20120301
Title: Folate malabsorption is associated with down-regulation of folate transporter expression and function at colon basolateral membrane in rats.
Journal: The British journal of nutrition 20120301
Title: Folinic acid supplementation in Rett syndrome patients does not influence the course of the disease: a randomized study.
Journal: Journal of child neurology 20120301
Title: Immediate pigment darkening: its evolutionary roles may include protection against folate photosensitization.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120301
Title: Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate.
Journal: Biochimica et biophysica acta 20120201
Title: Thermal oxidation studies on reduced folate, L-5-methyltetrahydrofolic acid (L-5-MTHF) and strategies for stabilization using food matrices.
Journal: Journal of food science 20120201
Title: Comparable levels of folate-induced aneusomy in B-lymphoblasts from oral-cleft patients and controls.
Journal: Mutation research 20120124
Title: Aberrant hepatic methionine metabolism and gene methylation in the pathogenesis and treatment of alcoholic steatohepatitis.
Journal: International journal of hepatology 20120101
Title: Folate status and homocysteine levels during a 24-week oral administration of a folate-containing oral contraceptive: a randomized, double-blind, active-controlled, parallel-group, US-based multicenter study.
Journal: Contraception 20120101
Title: Beyaz®: an oral contraceptive fortified with folate.
Journal: Women's health (London, England) 20120101
Title: Association of methylentetraydrofolate reductase (MTHFR) 677 C > T gene polymorphism and homocysteine levels in psoriasis vulgaris patients from Malaysia: a case-control study.
Journal: Nutrition journal 20120101
Title: Cancer risk with folic acid supplements: a systematic review and meta-analysis.
Journal: BMJ open 20120101
Title: Effect of n-3 polyunsaturated fatty acid on gene expression of the critical enzymes involved in homocysteine metabolism.
Journal: Nutrition journal 20120101
Title: Nanomedicine: towards development of patient-friendly drug-delivery systems for oncological applications.
Journal: International journal of nanomedicine 20120101
Title: Hydrogen sulfide mitigates cardiac remodeling during myocardial infarction via improvement of angiogenesis.
Journal: International journal of biological sciences 20120101
Title: A comprehensive review of the genetic basis of cleft lip and palate.
Journal: Journal of oral and maxillofacial pathology : JOMFP 20120101
Title: Association of the MTHFR A1298C variant with unexplained severe male infertility.
Journal: PloS one 20120101
Title: Serum unmetabolized folic acid in a nationally representative sample of adults ≥60 years in the United States, 2001-2002.
Journal: Food & nutrition research 20120101
Title: Circulating unmetabolized folic Acid: relationship to folate status and effect of supplementation.
Journal: Obstetrics and gynecology international 20120101
Title: Folate intake and methylenetetrahydrofolate reductase gene polymorphisms as predictive and prognostic biomarkers for ovarian cancer risk.
Journal: International journal of molecular sciences 20120101
Title: Folic acid transport to the human fetus is decreased in pregnancies with chronic alcohol exposure.
Journal: PloS one 20120101
Title: The effect of folic acid based homocysteine lowering on cardiovascular events in people with kidney disease: systematic review and meta-analysis.
Journal: BMJ (Clinical research ed.) 20120101
Title: The Genetic Diversity and Structure of Linkage Disequilibrium of the MTHFR Gene in Populations of Northern Eurasia.
Journal: Acta naturae 20120101
Title: Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease.
Journal: Journal of Alzheimer's disease : JAD 20120101
Title: Effect of dietary supplementation with folate on choline deficiency-induced hyperhomocysteinemia in rats.
Journal: Journal of nutritional science and vitaminology 20120101
Title: The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters.
Journal: The Journal of biological chemistry 20111230
Title: Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA.
Journal: The Journal of biological chemistry 20111223
Title: Targeted insertion of two Mthfr promoters in mice reveals temporal- and tissue-specific regulation.
Journal: Mammalian genome : official journal of the International Mammalian Genome Society 20111201
Title: Folic acid supplementation reduces oxidative stress and hepatic toxicity in rats treated chronically with ethanol.
Journal: Nutrition research and practice 20111201
Title: Cerebral folate deficiency: a neurometabolic syndrome?
Journal: Molecular genetics and metabolism 20111101
Title: Biochemical parameters to assess choroid plexus dysfunction in Kearns-Sayre syndrome patients.
Journal: Mitochondrion 20111101
Title: Methylenetetrahydrofolate reductase (MTHFR) deficiency and infantile epilepsy.
Journal: Brain & development 20111001
Title: Prevention of neural-tube defects with periconceptional folic acid, methylfolate, or multivitamins?
Journal: Annals of nutrition & metabolism 20111001
Title: The combined oral contraceptive pill containing drospirenone and ethinyl estradiol plus levomefolate calcium.
Journal: Expert opinion on pharmacotherapy 20111001
Title: Oral contraceptive use: impact on folate, vitamin B₆, and vitamin B₁₂ status.
Journal: Nutrition reviews 20111001
Title: The role of methylenetetrahydrofolate reductase C677T polymorphism on the peripheral blood natural killer cell proportion in women with unexplained recurrent miscarriages.
Journal: Clinical and experimental reproductive medicine 20110901
Title: Influence of high-pressure processing on the profile of polyglutamyl 5-methyltetrahydrofolate in selected vegetables.
Journal: Journal of agricultural and food chemistry 20110824
Title: Using logic programming for modeling the one-carbon metabolism network to study the impact of folate deficiency on methylation processes.
Journal: Molecular bioSystems 20110801
Title: Folate analysis in foods by UPLC-MS/MS: development and validation of a novel, high throughput quantitative assay; folate levels determined in Australian fortified breads.
Journal: Analytical and bioanalytical chemistry 20110801
Title: Maternal serum folate species in early pregnancy and lower genital tract inflammatory milieu.
Journal: American journal of obstetrics and gynecology 20110701
Title: Relationship between dietary folate intake and plasma monocyte chemoattractant protein-1 and interleukin-8 in heart failure patients.
Journal: Journal of clinical biochemistry and nutrition 20110701
Title: Concentrations of unmetabolized folic acid and primary folate forms in plasma after folic acid treatment in older adults.
Journal: Metabolism: clinical and experimental 20110501
Title: Cerebral folate deficiency syndromes in childhood: clinical, analytical, and etiologic aspects.
Journal: Archives of neurology 20110501
Title: Bacterial conversion of folinic acid is required for antifolate resistance.
Journal: The Journal of biological chemistry 20110429
Title: Pyridoxal 5'-phosphate in cerebrospinal fluid; factors affecting concentration.
Journal: Journal of inherited metabolic disease 20110401
Title: Intracellular trafficking considerations in the development of natural ligand-drug molecular conjugates for cancer.
Journal: Annals of biomedical engineering 20110401
Title: Effect of paternal folate deficiency on placental folate content and folate receptor α expression in rats.
Journal: Nutrition research and practice 20110401
Title: Human folate bioavailability.
Journal: Nutrients 20110401
Title: Methyl Vitamin B12 but not methylfolate rescues a motor neuron-like cell line from homocysteine-mediated cell death.
Journal: Toxicology and applied pharmacology 20110315
Title: MTHFR C677T polymorphism as a risk factor for vascular calcification in chronic hemodialysis patients.
Journal: Journal of Korean medical science 20110301
Title: Folic acid food fortification-its history, effect, concerns, and future directions.
Journal: Nutrients 20110301
Title: The homocysteine controversy.
Journal: Journal of inherited metabolic disease 20110201
Title: Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects.
Journal: Journal of inherited metabolic disease 20110201
Title: MTHFR polymorphisms and breast cancer risk.
Journal: Archives of medical science : AMS 20110201
Title: Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase.
Journal: Journal of lipid research 20110101
Title: Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney.
Journal: American journal of physiology. Renal physiology 20110101
Title: Functional characterization of folic acid transport in the intestine of the laying hen using the everted intestinal sac model.
Journal: Poultry science 20110101
Title: L-methylfolate Plus SSRI or SNRI from Treatment Initiation Compared to SSRI or SNRI Monotherapy in a Major Depressive Episode.
Journal: Innovations in clinical neuroscience 20110101
Title: Genotype networks, innovation, and robustness in sulfur metabolism.
Journal: BMC systems biology 20110101
Title: Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study.
Journal: BMC medical genetics 20110101
Title: Genetic polymorphisms in folate pathway enzymes, DRD4 and GSTM1 are related to temporomandibular disorder.
Journal: BMC medical genetics 20110101
Title: Folic acid fortification: why not vitamin B12 also?
Journal: BioFactors (Oxford, England) 20110101
Title: Assessment of the vitamin B12 status of pregnant women in Nigeria using plasma holotranscobalamin.
Journal: ISRN obstetrics and gynecology 20110101
Title: Control of prostate cancer associated with withdrawal of a supplement containing folic acid, L-methyltetrahydrofolate and vitamin B12: a case report.
Journal: Journal of medical case reports 20110101
Title: Mathematical model insights into arsenic detoxification.
Journal: Theoretical biology & medical modelling 20110101
Title: No effect of folic acid supplementation on global DNA methylation in men and women with moderately elevated homocysteine.
Journal: PloS one 20110101
Title: Genetic interactions between MTHFR (C677T), methionine synthase (A2756G, C2758G) variants with vitamin B12 and folic acid determine susceptibility to premature coronary artery disease in Indian population.
Journal: Journal of cardiovascular disease research 20110101
Title: Folate metabolic pathways in Leishmania.
Journal: Essays in biochemistry 20110101
Title: Haplotype analysis of the 5,10-methylenetetrahydrofolate reductase (MTHFR) c.1298A>C (E429A) polymorphism.
Journal: BMC research notes 20110101
Title: Methylenetetrahydrofolate reductase polymorphisms and interaction with smoking and alcohol consumption in lung cancer risk: a case-control study in a Japanese population.
Journal: BMC cancer 20110101
Title: Comprehensive evaluation of one-carbon metabolism pathway gene variants and renal cell cancer risk.
Journal: PloS one 20110101
Title: Folic acid modified gelatine coated quantum dots as potential reagents for in vitro cancer diagnostics.
Journal: Journal of nanobiotechnology 20110101
Title: The MetJ regulon in gammaproteobacteria determined by comparative genomics methods.
Journal: BMC genomics 20110101
Title: Xenopus reduced folate carrier regulates neural crest development epigenetically.
Journal: PloS one 20110101
Title: The association of DNA damage response and nucleotide level modulation with the antibacterial mechanism of the anti-folate drug trimethoprim.
Journal: BMC genomics 20110101
Title: Biochemical and molecular mechanisms of folate transport in rat pancreas; interference with ethanol ingestion.
Journal: PloS one 20110101
Title: Incidence of down syndrome: Hypotheses and reality.
Journal: Indian journal of human genetics 20110101
Title: Neural tube defects between folate metabolism and genetics.
Journal: Indian journal of human genetics 20110101
Title: The Fox and the Rabbits-Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease.
Journal: ISRN neurology 20110101
Title: Progressive ataxia and myoclonic epilepsy in a patient with a homozygous mutation in the FOLR1 gene.
Journal: Journal of inherited metabolic disease 20101201
Title: The Micronutrient Genomics Project: a community-driven knowledge base for micronutrient research.
Journal: Genes & nutrition 20101201
Title: Pilot study of folate status in healthy volunteers and in patients with psoriasis before and after UV exposure.
Journal: Journal of photochemistry and photobiology. B, Biology 20101103
Title: Molecular characterization of five patients with homocystinuria due to severe methylenetetrahydrofolate reductase deficiency.
Journal: Clinical genetics 20101101
Title: Properties of the Arg376 residue of the proton-coupled folate transporter (PCFT-SLC46A1) and a glutamine mutant causing hereditary folate malabsorption.
Journal: American journal of physiology. Cell physiology 20101101
Title: The transcobalamin (TCN2) 776C>G polymorphism affects homocysteine concentrations among subjects with low vitamin B(12) status.
Journal: European journal of clinical nutrition 20101101
Title: A liquid chromatography-tandem mass spectrometric method for quantitative determination of native 5-methyltetrahydrofolate and its polyglutamyl derivatives in raw vegetables.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101101
Title: Genetic disorders of vitamin B₁₂ metabolism: eight complementation groups--eight genes.
Journal: Expert reviews in molecular medicine 20101101
Title: Cerebral folate deficiency.
Journal: Journal of inherited metabolic disease 20101001
Title: Analysis of 5-methyltetrahydrofolate in human blood, serum and urine by on-line coupling of capillary isotachophoresis and zone electrophoresis.
Journal: Electrophoresis 20101001
Title: Proton-coupled folate transporter (PCFT): molecular cloning, tissue expression patterns and the effects of dietary folate supplementation on mRNA expression in laying hens.
Journal: British poultry science 20101001
Title: Production of folate by bacteria isolated from oat bran.
Journal: International journal of food microbiology 20100930
Title: Folates in bread: retention during bread-making and in vitro bioaccessibility.
Journal: European journal of nutrition 20100901
Title: Reduced de novo synthesis of 5-methyltetrahydrofolate and reduced taurine levels in ethanol-treated chick brains.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100901
Title: Effect of antiepileptic drugs and reactive oxygen species on folate receptor 1 (FOLR1)-dependent 5-methyltetrahydrofolate transport.
Journal: Molecular genetics and metabolism 20100901
Title: Glucarpidase, leucovorin, and thymidine for high-dose methotrexate-induced renal dysfunction: clinical and pharmacologic factors affecting outcome.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100901
Title: Folic Acid supplementation stimulates notch signaling and cell proliferation in embryonic neural stem cells.
Journal: Journal of clinical biochemistry and nutrition 20100901
Title: One-carbon metabolism in plants: characterization of a plastid serine hydroxymethyltransferase.
Journal: The Biochemical journal 20100815
Title: Kearns-Sayre syndrome: cerebral folate deficiency, MRI findings and new cerebrospinal fluid biochemical features.
Journal: Mitochondrion 20100801
Title: Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics.
Journal: Clinical pharmacokinetics 20100801
Title: Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity.
Journal: Toxins 20100801
Title: Quantification of folate in fruits and vegetables: A fluorescence-based homogeneous assay.
Journal: Analytical biochemistry 20100715
Title: Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition.
Journal: Molecular and biochemical parasitology 20100701
Title: Cerebral folate deficiency presenting as adolescent catatonic schizophrenia: a case report.
Journal: Journal of child neurology 20100701
Title: [No association between MTHFR 677C>T polymorphism and ovarian cancer risk in BRCA1 mutation carriers in Wielkopolska region].
Journal: Ginekologia polska 20100701
Title: Decreased level of 5-methyltetrahydrofolate: a potential biomarker for pre-symptomatic amyotrophic lateral sclerosis.
Journal: Journal of the neurological sciences 20100615
Title: Crystal structure of aminomethyltransferase in complex with dihydrolipoyl-H-protein of the glycine cleavage system: implications for recognition of lipoyl protein substrate, disease-related mutations, and reaction mechanism.
Journal: The Journal of biological chemistry 20100611
Title: Acute effects of 5-methyltetrahydrofolate on endothelial function and asymmetric dimethylarginine in patients with chronic heart failure.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20100601
Title: Molecular and biochemical characterization of folate transport proteins in retinal Müller cells.
Journal: Investigative ophthalmology & visual science 20100601
Title: Life-threatening methylenetetrahydrofolate reductase (MTHFR) deficiency with extremely early onset: characterization of two novel mutations in compound heterozygous patients.
Journal: Molecular genetics and metabolism 20100601
Title: One-carbon metabolism and Alzheimer's disease: focus on epigenetics.
Journal: Current genomics 20100601
Title: Influence of reducing carbohydrates on (6S)-5-methyltetrahydrofolic acid degradation during thermal treatments.
Journal: Journal of agricultural and food chemistry 20100526
Title: Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation.
Journal: Journal of proteome research 20100405
Title: Photobiological implications of folate depletion and repletion in cultured human keratinocytes.
Journal: Journal of photochemistry and photobiology. B, Biology 20100402
Title: Basolateral efflux mediated by multidrug resistance-associated protein 3 (Mrp3/Abcc3) facilitates intestinal absorption of folates in mouse.
Journal: Pharmaceutical research 20100401
Title: Characterization of folate-dependent enzymes and indices of folate status in laying hens supplemented with folic acid or 5-methyltetrahydrofolate.
Journal: Poultry science 20100401
Title: Major determinants of serum homocysteine concentrations in a Korean population.
Journal: Journal of Korean medical science 20100401
Title: Comparison of (6 S)-5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietary intervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-week placebo-controlled study in healthy adults.
Journal: The British journal of nutrition 20100301
Title: The role of folate receptor alpha (FRalpha) in the response of malignant pleural mesothelioma to pemetrexed-containing chemotherapy.
Journal: British journal of cancer 20100202
Title: Homocysteine levels in chronic gastritis and other conditions: relations to incident cardiovascular disease and dementia.
Journal: Digestive diseases and sciences 20100201
Title: Expression of folate transporters in human placenta and implications for homocysteine metabolism.
Journal: Placenta 20100201
Title: Cerebral folate deficiency and CNS inflammatory markers in Alpers disease.
Journal: Molecular genetics and metabolism 20100101
Title: Quantification of key folate forms in serum using stable-isotope dilution ultra performance liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100101
Title: Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70.
Journal: PLoS genetics 20100101
Title: The B-VITAGE trial: a randomized trial of homocysteine lowering treatment of depression in later life.
Journal: Trials 20100101
Title: L-methylfolate, methylcobalamin, and N-acetylcysteine in the treatment of Alzheimer's disease-related cognitive decline.
Journal: CNS spectrums 20100101
Title: Commentary on: L-methylfolate, methylcobolamine, and N-acetylcysteine in the treatment of Alzheimer's disease-related cognitive decline.
Journal: CNS spectrums 20100101
Title: A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis.
Journal: Arthritis research & therapy 20100101
Title: Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population.
Journal: BMC cancer 20100101
Title: Analysis of the MTHFR C677T variant with migraine phenotypes.
Journal: BMC research notes 20100101
Title: Plasma folate levels are associated with the lipoprotein profile: a retrospective database analysis.
Journal: Nutrition journal 20100101
Title: Nutriomes and nutrient arrays - the key to personalised nutrition for DNA damage prevention and cancer growth control.
Journal: Genome integrity 20100101
Title: Polymorphisms in folate-metabolizing genes, chromosome damage, and risk of Down syndrome in Italian women: identification of key factors using artificial neural networks.
Journal: BMC medical genomics 20100101
Title: SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer.
Journal: BMC cancer 20100101
Title: Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial.
Journal: BMJ (Clinical research ed.) 20100101
Title: Polymorphisms of methylenetetrahydrofolate reductase gene as the genetic predispositions of coronary artery diseases in eastern India.
Journal: Journal of cardiovascular disease research 20100101
Title: Improvement of cutaneous sensitivity in diabetic peripheral neuropathy with combination L-methylfolate, methylcobalamin, and pyridoxal 5'-phosphate.
Journal: Reviews in neurological diseases 20100101
Title: Methionine synthase polymorphisms (MTR 2756 A>G and MTR 2758 C>G) frequencies and distribution in the Jordanian population and their correlation with neural tube defects in the population of the northern part of Jordan.
Journal: Indian journal of human genetics 20100101
Title: Potential for development of an Escherichia coli-based biosensor for assessing bioavailable methionine: a review.
Journal: Sensors (Basel, Switzerland) 20100101
Title: [6S]-5-methyltetrahydrofolate increases plasma folate more effectively than folic acid in women with the homozygous or wild-type 677C-->T polymorphism of methylenetetrahydrofolate reductase.
Journal: British journal of pharmacology 20091201
Title: Effects of a low-fat meal on the oral bioavailability of UFT and leucovorin in patients with colorectal cancer.
Journal: International journal of clinical oncology 20091201
Title: Combining antidepressant therapies from the initiation of treatment: a paradigm shift for major depression.
Journal: The Journal of clinical psychiatry 20091101
Title: 5-Methyltetrahydrofolate can be photodegraded by endogenous photosensitizers.
Journal: Free radical biology & medicine 20091015
Title: [6S]-5-Methyltetrahydrofolate enhances folate status in rats fed growing-up milk.
Journal: European journal of nutrition 20090901
Title: Randomized clinical trial of folate supplementation in patients with peripheral arterial disease.
Journal: The British journal of surgery 20090901
Title: Molecular cloning and tissue distribution of reduced folate carrier and effect of dietary folate supplementation on the expression of reduced folate carrier in laying hens.
Journal: Poultry science 20090901
Title: Folate and homocysteine phenotypes: Comparative findings using research and clinical laboratory data.
Journal: Clinical biochemistry 20090801
Title: Site-specific contribution of proton-coupled folate transporter/haem carrier protein 1 in the intestinal absorption of methotrexate in rats.
Journal: The Journal of pharmacy and pharmacology 20090701
Title: Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.
Journal: Journal of molecular biology 20090619
Title: Erythrocyte folate and 5-methyltetrahydrofolate levels decline during 6 months of oral anticoagulation with warfarin.
Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20090601
Title: Liquid chromatography-tandem mass spectrometry analysis of folate and folate catabolites in human serum.
Journal: Clinical chemistry 20090601
Title: MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis.
Journal: Circulation 20090512
Title: C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation.
Journal: European journal of cancer (Oxford, England : 1990) 20090501
Title: Simultaneous determination of 6R-leucovorin, 6S-leucovorin and 5-methyltetrahydrofolate in human plasma using solid phase extraction and chiral liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090401
Title: Phasevarions mediate random switching of gene expression in pathogenic Neisseria.
Journal: PLoS pathogens 20090401
Title: Photodegradation of 5-methyltetrahydrofolate in the presence of Uroporphyrin.
Journal: Journal of photochemistry and photobiology. B, Biology 20090303
Title: Cerebral folate deficiency.
Journal: Developmental medicine and child neurology 20090301
Title: Effects of UVA irradiation on the concentration of folate in human blood.
Journal: Bioscience, biotechnology, and biochemistry 20090201
Title: Methotrexate-associated alterations of the folate and methyl-transfer pathway in the CSF of ALL patients with and without symptoms of neurotoxicity.
Journal: Pediatric blood & cancer 20090101
Title: Preliminary evidence for cell membrane amelioration in children with cystic fibrosis by 5-MTHF and vitamin B12 supplementation: a single arm trial.
Journal: PloS one 20090101
Title: Study Protocol: randomised controlled trial to investigate the functional significance of marginal riboflavin status in young women in the UK (RIBOFEM).
Journal: BMC public health 20090101
Title: Dietary intake of folate, vitamin B6, and vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Brazilian women.
Journal: BMC cancer 20090101
Title: Genetic variation in the methylenetetrahydrofolate reductase gene, MTHFR, does not alter the risk of visual failure in Leber's hereditary optic neuropathy.
Journal: Molecular vision 20090101
Title: Lack of association between genetic polymorphisms in enzymes associated with folate metabolism and unexplained reduced sperm counts.
Journal: PloS one 20090101
Title: Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease.
Journal: Journal of Alzheimer's disease : JAD 20090101
Title: Persistent circulating unmetabolised folic acid in a setting of liberal voluntary folic acid fortification. Implications for further mandatory fortification?
Journal: BMC public health 20090101
Title: Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: a case-control pilot study.
Journal: Cardiovascular diabetology 20090101
Title: Plasma homocysteine in adolescents depends on the interaction between methylenetetrahydrofolate reductase genotype, lipids and folate: a seroepidemiological study.
Journal: Nutrition & metabolism 20090101
Title: AI-2 does not function as a quorum sensing molecule in Campylobacter jejuni during exponential growth in vitro.
Journal: BMC microbiology 20090101
Title: DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase.
Journal: PloS one 20090101
Title: Current concepts in genetics of nonsyndromic clefts.
Journal: Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India 20090101
Title: Directed therapy for exfoliation syndrome.
Journal: The open ophthalmology journal 20090101
Title: A novel lipidomic strategy reveals plasma phospholipid signatures associated with respiratory disease severity in cystic fibrosis patients.
Journal: PloS one 20090101
Title: Folate in depression: efficacy, safety, differences in formulations, and clinical issues.
Journal: The Journal of clinical psychiatry 20090101
Title: MTHFR gene C677T and A1298C polymorphisms and homocysteine levels in primary open angle and primary closed angle glaucoma.
Journal: Molecular vision 20090101
Title: Association between SOD2 T-9C and MTHFR C677T polymorphisms and longevity: a study in Jordanian population.
Journal: BMC geriatrics 20090101
Title: MTHFR C677T and postmenopausal breast cancer risk by intakes of one-carbon metabolism nutrients: a nested case-control study.
Journal: Breast cancer research : BCR 20090101
Title: [The level of low molecular thiols and folate in human placenta].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20090101
Title: Methods to evaluate the effect of ethanol on the folate analogue: fluorescein methotrexate uptake in human proximal tubular cells.
Journal: Advances in pharmacological sciences 20090101
Title: [Supplementation with folic acid before and during pregnancy].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20081201
Title: Technical and biochemical factors affecting cerebrospinal fluid 5-MTHF, biopterin and neopterin concentrations.
Journal: Molecular genetics and metabolism 20081101
Title: Root proteomic responses to heat stress in two Agrostis grass species contrasting in heat tolerance.
Journal: Journal of experimental botany 20081101
Title: L-ascorbic acid improves the serum folate response to an oral dose of [6S]-5-methyltetrahydrofolic acid in healthy men.
Journal: European journal of clinical nutrition 20081001
Title: 5-methyltetrahydrofolate administration is associated with prolonged survival and reduced inflammation in ESRD patients.
Journal: American journal of nephrology 20081001
Title: [Genetic diversity and the structure of linkage disequilibrium in the methylenetetrahydrofolate reductase locus].
Journal: Genetika 20081001
Title: Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice.
Journal: The Journal of biological chemistry 20080919
Title: No association with the 5,10-methylenetetrahydrofolate reductase gene and major depressive disorder: results of the depression case control (DeCC) study and a meta-analysis.
Journal: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20080905
Title: Acetylation of N-terminal valine of glycine N-methyltransferase affects enzyme inhibition by folate.
Journal: Biochimica et biophysica acta 20080901
Title: Commutability of NIST SRM 1955 Homocysteine and Folate in Frozen Human Serum with selected total homocysteine immunoassays and enzymatic assays.
Journal: Clinica chimica acta; international journal of clinical chemistry 20080901
Title: Genome-wide pathway analysis of folate-responsive genes to unravel the pathogenesis of orofacial clefting in man.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20080901
Title: Top-down analysis of temporal hierarchy in biochemical reaction networks.
Journal: PLoS computational biology 20080901
Title: The methylation, neurotransmitter, and antioxidant connections between folate and depression.
Journal: Alternative medicine review : a journal of clinical therapeutic 20080901
Title: L-methylfolate: a vitamin for your monoamines.
Journal: The Journal of clinical psychiatry 20080901
Title: A systematic review of meta-analyses on gene polymorphisms and gastric cancer risk.
Journal: Current genomics 20080901
Title: Production of folates by yeasts in Tanzanian fermented togwa.
Journal: FEMS yeast research 20080801
Title: Neural tube defects and disturbed maternal folate- and homocysteine-mediated one-carbon metabolism.
Journal: Experimental neurology 20080801
Title: Two newly synthesized 5-methyltetrahydrofolate-like compounds inhibit methionine synthase activity accompanied by cell cycle arrest in G1/S phase and apoptosis in vitro.
Journal: Anti-cancer drugs 20080801
Title: Quantification of key red blood cell folates from subjects with defined MTHFR 677C>T genotypes using stable isotope dilution liquid chromatography/mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20080801
Title: Brief report: autistic symptoms, developmental regression, mental retardation, epilepsy, and dyskinesias in CNS folate deficiency.
Journal: Journal of autism and developmental disorders 20080701
Title: Embryonic development in the reduced folate carrier knockout mouse is modulated by maternal folate supplementation.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20080701
Title: Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice.
Journal: Pharmacogenetics and genomics 20080701
Title: 5-Methyltetrahydrofolate is photosensitive in the presence of riboflavin.
Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080701
Title: The folic acid metabolite L-5-methyltetrahydrofolate effectively reduces total serum homocysteine level in orthotopic liver transplant recipients: a double-blind placebo-controlled study.
Journal: European journal of clinical nutrition 20080601
Title: Folate stimulation of wound DNA synthesis.
Journal: The Journal of surgical research 20080601
Title: Photoinduced fluorimetric determination of folic acid and 5-methyltetrahydrofolic acid in serum using the kinetic evolution of the emission spectra accomplished with multivariate second-order calibration methods.
Journal: Analytical and bioanalytical chemistry 20080601
Title: Mefolinate (5-methyltetrahydrofolate), but not folic acid, decreases mortality in an animal model of severe methylenetetrahydrofolate reductase deficiency.
Journal: Journal of inherited metabolic disease 20080601
Title: Diffuse multicystic encephalomalacia in a preterm baby due to homozygous methylenetetrahydrofolate reductase 677 C-->T mutation.
Journal: Journal of child neurology 20080601
Title: Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer.
Journal: Parasitology research 20080501
Title: Folate content in sea buckthorn berries and related products (Hippophaë rhamnoides L. ssp. rhamnoides): LC-MS/MS determination of folate vitamer stability influenced by processing and storage assessed by stable isotope dilution assay.
Journal: Analytical and bioanalytical chemistry 20080501
Title: An allosteric mechanism for switching between parallel tracks in mammalian sulfur metabolism.
Journal: PLoS computational biology 20080501
Title: How does folic acid cure heart attacks?
Journal: Circulation 20080408
Title: Evaluation of the relationship between C677T variants of methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in children receiving antiepileptic drug therapy.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080401
Title: Measurement of folate in fresh and archival serum samples as p-aminobenzoylglutamate equivalents.
Journal: Clinical chemistry 20080401
Title: Hyperhomocysteinaemia and endothelial dysfunction in dialysis patients: what should be treated first?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080301
Title: Characterization of folate uptake by choroid plexus epithelial cells in a rat primary culture model.
Journal: Journal of neurochemistry 20080301
Title: Impaired clearance of methotrexate in organic anion transporter 3 (Slc22a8) knockout mice: a gender specific impact of reduced folates.
Journal: Pharmaceutical research 20080201
Title: Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study.
Journal: Diabetologia 20080101
Title: Juvenile onset central nervous system folate deficiency and rheumatoid arthritis.
Journal: Journal of child neurology 20080101
Title: Decreased plasma folate concentration in young and elderly healthy subjects after a short-term supplementation with isotretinoin.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20080101
Title: Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex.
Journal: BMC genomics 20080101
Title: A mathematical model of glutathione metabolism.
Journal: Theoretical biology & medical modelling 20080101
Title: Genotyping panel for assessing response to cancer chemotherapy.
Journal: BMC medical genomics 20080101
Title: Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms resulting in suboptimal oocyte maturation: a discussion of folate status, neural tube defects, schizophrenia, and vasculopathy.
Journal: Journal of experimental & clinical assisted reproduction 20080101
Title: Age-specific epigenetic drift in late-onset Alzheimer's disease.
Journal: PloS one 20080101
Title: Methionine synthase A2756G polymorphism may predict ulcerative colitis and methylenetetrahydrofolate reductase C677T pancolitis, in Central China.
Journal: BMC medical genetics 20080101
Title: Involvement of reduced folate carrier 1 in the inner blood-retinal barrier transport of methyltetrahydrofolate.
Journal: Drug metabolism and pharmacokinetics 20080101
Title: Folate deprivation, the methionine cycle, and Alzheimer's disease.
Journal: Vitamins and hormones 20080101
Title: Methyltetrahydrofolate in folate-binding protein glycine N-methyltransferase.
Journal: Vitamins and hormones 20080101
Title: Methylenetetrahydrofolate reductase, common polymorphisms, and relation to disease.
Journal: Vitamins and hormones 20080101
Title: Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.
Journal: BMC cancer 20080101
Title: Human genetic selection on the MTHFR 677C>T polymorphism.
Journal: BMC medical genetics 20080101
Title: Treatment-resistant depression: recent developments and future directions.
Journal: Depression and anxiety 20080101
Title: In vitro inhibition of 10-formyltetrahydrofolate dehydrogenase activity by acetaldehyde.
Journal: Nutrition research and practice 20080101
Title: The role of vitamins and minerals in psychiatry.
Journal: Integrative medicine insights 20080101
Title: Folate receptor autoimmunity and cerebral folate deficiency in low-functioning autism with neurological deficits.
Journal: Neuropediatrics 20071201
Title: Improvement of endothelial function in uraemic patients on peritoneal dialysis: a possible role for 5-MTHF administration.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071101
Title: Folate receptor and human reduced folate carrier expression in HepG2 cell line exposed to fumonisin B1 and folate deficiency.
Journal: Carcinogenesis 20071101
Title: Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction.
Journal: American journal of physiology. Cell physiology 20071101
Title: Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types.
Journal: Investigative ophthalmology & visual science 20071101
Title: Methylenetetrahydrofolate reductase (MTHFR) variants and fluorouracil-based treatments in colorectal cancer.
Journal: Pharmacogenomics 20071101
Title: Responses of biomarkers of folate and riboflavin status to folate and riboflavin supplementation in healthy and colorectal polyp patients (the FAB2 Study).
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20071001
Title: Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices.
Journal: The Journal of pharmacology and experimental therapeutics 20070901
Title: Marked elevation in homocysteine and homocysteine sulfinic acid in the cerebrospinal fluid of lymphoma patients receiving intensive treatment with methotrexate.
Journal: International journal of clinical pharmacology and therapeutics 20070901
Title: Possible mechanisms for the pharmacokinetic interaction between phenytoin and folinate in rats.
Journal: Therapeutic drug monitoring 20070801
Title: Dose-dependent effects of (anti)folate preinjection on 99mTc-radiofolate uptake in tumors and kidneys.
Journal: Nuclear medicine and biology 20070801
Title: Folate receptor autoantibodies and spinal fluid 5-methyltetrahydrofolate deficiency in Rett syndrome.
Journal: Neuropediatrics 20070801
Title: Mitochondrial complex I encephalomyopathy and cerebral 5-methyltetrahydrofolate deficiency.
Journal: Neuropediatrics 20070801
Title: Two Aspergillus nidulans genes encoding methylenetetrahydrofolate reductases are up-regulated by homocysteine.
Journal: Fungal genetics and biology : FG & B 20070701
Title: 5-Methyltetrahydrofolate inhibits photosensitization reactions and strand breaks in DNA.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701
Title: Characterisation of exogenous folate transport in Plasmodium falciparum.
Journal: Molecular and biochemical parasitology 20070701
Title: Commentary: a case for minimizing folate supplementation in clinical regimens with pemetrexed based on the marked sensitivity of the drug to folate availability.
Journal: The oncologist 20070701
Title: Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency.
Journal: Molecular genetics and metabolism 20070601
Title: Global improvement of vascular function and redox state with low-dose folic acid: implications for folate therapy in patients with coronary artery disease.
Journal: Circulation 20070501
Title: The folate receptor alpha is frequently overexpressed in osteosarcoma samples and plays a role in the uptake of the physiologic substrate 5-methyltetrahydrofolate.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070501
Title: Patient information. Planning for pregnancy.
Journal: Advance for nurse practitioners 20070501
Title: [Folic acid dose in the prevention of congenital defects].
Journal: Medicina clinica 20070428
Title: Cardiovascular abnormalities in Folr1 knockout mice and folate rescue.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20070401
Title: Application of liquid chromatography-electrospray ionisation mass spectrometry for determination of dietary folates: effects of buffer nature and mobile phase composition on sensitivity and selectivity.
Journal: Journal of chromatography. A 20070302
Title: Molecular phylogenetic analysis of methylenetetrahydrofolate reductase family of proteins.
Journal: Molecular phylogenetics and evolution 20070301
Title: 5-methyltetrahydrofolic acid stimulates endothelin-1 production in low density lipoprotein-treated human endothelial cells.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20070301
Title: Significant impact of MTHFR C677T polymorphism on plasma homovanillic acid (HVA) levels among alcohol-dependent patients.
Journal: Addiction biology 20070301
Title: 5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase.
Journal: The Journal of biological chemistry 20070209
Title: No association between methylenetetrahydrofolate reductase C677T polymorphism and breast cancer.
Journal: Cell biochemistry and function 20070101
Title: Is the seasonal variation in cancer prognosis caused by sun-induced folate degradation?
Journal: Medical hypotheses 20070101
Title: Photodegradation of folic acid during extracorporeal photopheresis.
Journal: The British journal of dermatology 20070101
Title: Cerebral folate deficiency and folinic acid treatment in hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) syndrome.
Journal: The Tohoku journal of experimental medicine 20070101
Title: Inhibition of cobalamin-dependent methionine synthase by substituted benzo-fused heterocycles.
Journal: The FEBS journal 20070101
Title: High-dose folate may improve platelet function in acute coronary syndrome and other pathologies associated with increased platelet oxidative stress.
Journal: Medical hypotheses 20070101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20070101
Title: Folic acid fortification and public health: report on threshold doses above which unmetabolised folic acid appear in serum.
Journal: BMC public health 20070101
Title: pH stability of individual folates during critical sample preparation steps in prevision of the analysis of plant folates.
Journal: Phytochemical analysis : PCA 20070101
Title: Folate: in vitro and in vivo effects on VLDL and LDL oxidation.
Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070101
Title: Homocysteine lowering: any use in atherosclerosis?
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20070101
Title: [Smoking influence on the level of homocysteine and 5-methyltetrahydrofolic acid in active and non smokers].
Journal: Przeglad lekarski 20070101
Title: Folate during reproduction: the Canadian experience with folic acid fortification.
Journal: Nutrition research and practice 20070101
Title: Risk of Down syndrome conferred by MTHFR C677T polymorphism: Ethnic variations.
Journal: Indian journal of human genetics 20070101
Title: Nitric oxide and cardiovascular risk factors.
Journal: Heart international 20070101
Title: Difference in folate content of green and red sweet peppers (Capsicum annuum) determined by liquid chromatography-mass spectrometry.
Journal: Journal of agricultural and food chemistry 20061227
Title: Biochemical and genetic analysis of methylenetetrahydrofolate reductase in Leishmania metabolism and virulence.
Journal: The Journal of biological chemistry 20061215
Title: Effect of germination and thermal treatments on folates in rye.
Journal: Journal of agricultural and food chemistry 20061213
Title: Absorption of folate by Caco-2 cells is not affected by high glucose concentration.
Journal: European journal of pharmacology 20061203
Title: Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats.
Journal: American journal of physiology. Endocrinology and metabolism 20061201
Title: 5-methyltetrahydrofolate. Monograph.
Journal: Alternative medicine review : a journal of clinical therapeutic 20061201
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20061201
Title: Mitochondrial function and toxicity: role of B vitamins on the one-carbon transfer pathways.
Journal: Chemico-biological interactions 20061027
Title: Neural tube defects and folate pathway genes: family-based association tests of gene-gene and gene-environment interactions.
Journal: Environmental health perspectives 20061001
Title: 5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling.
Journal: Circulation 20060912
Title: Determination of 5-methyltetrahydrofolate in cerebrospinal fluid of paediatric patients: reference values for a paediatric population.
Journal: Clinica chimica acta; international journal of clinical chemistry 20060901
Title: Can 5-methyltetrahydrofolate modify the phospholipid fatty acid pattern in cystic fibrosis pediatric patients?
Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20060801
Title: Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than with folic acid in women of childbearing age.
Journal: The American journal of clinical nutrition 20060701
Title: The effect of docosahexaenoic acid and folic acid supplementation on placental apoptosis and proliferation.
Journal: The British journal of nutrition 20060701
Title: Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers.
Journal: British journal of cancer 20060619
Title: [Usefulness of analysis of cerebrospinal fluid for the diagnosis of neurotransmitters and pterin defects and glucose and folate transport deficiencies across blood brain barrier].
Journal: Medicina clinica 20060617
Title: Methylenetetrahydrofolate reductase gene polymorphisms: genomic predictors of clinical response to fluoropyrimidine-based chemotherapy?
Journal: Cancer chemotherapy and pharmacology 20060601
Title: Spontaneous neural tube defects in splotch mice supplemented with selected micronutrients.
Journal: Toxicology and applied pharmacology 20060515
Title: Evaluation of an ex vivo model implication for carrier-mediated retinal drug delivery.
Journal: Current eye research 20060501
Title: Acute effect of folic acid, betaine, and serine supplements on flow-mediated dilation after methionine loading: a randomized trial.
Journal: PLoS clinical trials 20060501
Title: Patient information. The importance of homocysteine.
Journal: Advance for nurse practitioners 20060501
Title: Activation of methyltetrahydrofolate by cobalamin-independent methionine synthase.
Journal: Biochemistry 20060425
Title: Effect of homocysteine lowering by 5-methyltetrahydrofolate on redox status in hyperhomocysteinemia.
Journal: Journal of cardiovascular pharmacology 20060401
Title: Cellular folate vitamer distribution during and after correction of vitamin B12 deficiency: a case for the methylfolate trap.
Journal: British journal of haematology 20060301
Title: Cerebral folate deficiency and leukoencephalopathy caused by a mitochondrial DNA deletion.
Journal: Annals of neurology 20060201
Title: Exposure to fumonisins and the occurrence of neural tube defects along the Texas-Mexico border.
Journal: Environmental health perspectives 20060201
Title: Folic acid reverses endothelial dysfunction induced by inhibition of tetrahydrobiopterin biosynthesis.
Journal: European journal of pharmacology 20060120
Title: Analysis of 5-methyltetrahydrofolate in serum of healthy children.
Journal: Molecular genetics and metabolism 20060101
Title: Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies.
Journal: Lipids in health and disease 20060101
Title: Quantitative determination of erythrocyte folate vitamer distribution by liquid chromatography-tandem mass spectrometry.
Journal: Clinical chemistry and laboratory medicine 20060101
Title: Photodegradation of 5-methyltetrahydrofolate: biophysical aspects.
Journal: Photochemistry and photobiology 20060101
Title: In silico experimentation with a model of hepatic mitochondrial folate metabolism.
Journal: Theoretical biology & medical modelling 20060101
Title: Association of red blood cell 5-methyltetrahydrofolate folate with bone mineral density in postmenopausal Iranian women.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20051201
Title: [6S]5-methyltetrahydrofolate or folic acid supplementation and absorption and initial elimination of folate in young and middle-aged adults.
Journal: European journal of clinical nutrition 20051201
Title: Cerebrospinal fluid concentrations of folate, biogenic amines and pterins in Rett syndrome: treatment with folinic acid.
Journal: Neuropediatrics 20051201
Title: Higher plant plastids and cyanobacteria have folate carriers related to those of trypanosomatids.
Journal: The Journal of biological chemistry 20051118
Title: Reduced in vivo oxidative stress following 5-methyltetrahydrofolate supplementation in patients with early-onset thrombosis and 677TT methylenetetrahydrofolate reductase genotype.
Journal: British journal of haematology 20051001
Title: The transmethylation cycle in the brain of Alzheimer patients.
Journal: Neuroscience letters 20050930
Title: Purification and properties of cobalamin-independent methionine synthase from Candida albicans and Saccharomyces cerevisiae.
Journal: Archives of biochemistry and biophysics 20050901
Title: Homocysteine-lowering therapy and early progression of transplant vasculopathy: a prospective, randomized, IVUS-based study.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901
Title: Association of red blood cell 5-methyltetrahydrofolate and severity of coronary artery disease: a cross-sectional study from Shiraz, southern Iran.
Journal: Heart and vessels 20050901
Title: Cerebral folate deficiency syndrome.
Journal: The New England journal of medicine 20050818
Title: Plant gamma-glutamyl hydrolases and folate polyglutamates: characterization, compartmentation, and co-occurrence in vacuoles.
Journal: The Journal of biological chemistry 20050812
Title: Postnatal cerebellar defects in mice deficient in methylenetetrahydrofolate reductase.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20050801
Title: Lack of association of methylenetetrahydrofolate reductase 677C>T mutation with coronary artery disease in a Pakistani population.
Journal: Journal of molecular and genetic medicine : an international journal of biomedical research 20050801
Title: Affinity and rate constants for interactions of bovine folate-binding protein and folate derivatives determined by optical biosensor technology. Effect of stereoselectivity.
Journal: Journal of agricultural and food chemistry 20050629
Title: Spinal fluid 5-methyltetrahydrofolate levels are normal in Rett syndrome.
Journal: Neurology 20050628
Title: Investigation of the extraction behavior of the main monoglutamate folates from spinach by liquid chromatography-electrospray ionization tandem mass spectrometry.
Journal: Journal of chromatography. A 20050617
Title: Effect of folate-binding protein on intestinal transport of folic acid and 5-methyltetrahydrofolate across Caco-2 cells.
Journal: European journal of nutrition 20050601
Title: Simultaneous quantification of homocysteine and folate in human serum or plasma using liquid chromatography/tandem mass spectrometry.
Journal: Analytical chemistry 20050601
Title: High-dose folic acid acutely improves coronary vasodilator function in patients with coronary artery disease.
Journal: Journal of the American College of Cardiology 20050517
Title: Autoantibodies to folate receptors in the cerebral folate deficiency syndrome.
Journal: The New England journal of medicine 20050512
Title: Homocysteine: overview of biochemistry, molecular biology, and role in disease processes.
Journal: Seminars in vascular medicine 20050501
Title: Investigation of systemic folate status, impact of alcohol intake and levels of DNA damage in mononuclear cells of breast cancer patients.
Journal: British journal of cancer 20050425
Title: Development of a simplified method for the determination of folates in baker's yeast by HPLC with ultraviolet and fluorescence detection.
Journal: Journal of agricultural and food chemistry 20050406
Title: S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050401
Title: Cerebral folate deficiency: life-changing supplementation with folinic acid.
Journal: Molecular genetics and metabolism 20050401
Title: Capillary electrophoresis and high-performance liquid chromatography determination of polyglutamyl 5-methyltetrahydrofolate forms in citrus products.
Journal: Journal of agricultural and food chemistry 20050323
Title: Cerebral folate deficiency with developmental delay, autism, and response to folinic acid.
Journal: Neurology 20050322
Title: Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic leukemia.
Journal: Cancer research 20050315
Title: Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer.
Journal: British journal of cancer 20050314
Title: Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation.
Journal: Biology of reproduction 20050301
Title: Folic acid: a marker of endothelial function in type 2 diabetes?
Journal: Vascular health and risk management 20050301
Title: Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure.
Journal: British journal of cancer 20050214
Title: Distribution of 5,10-methylenetetrahydrofolate reductase (C667T) polymorphism and its association with red blood cell 5-methyltetrahydrofolate in the healthy Iranians.
Journal: Clinical nutrition (Edinburgh, Scotland) 20050201
Title: Effects of betaine intake on plasma homocysteine concentrations and consequences for health.
Journal: Current drug metabolism 20050201
Title: Study of folate receptor genes in nonsyndromic familial and sporadic cleft lip with or without cleft palate cases.
Journal: American journal of medical genetics. Part A 20050130
Title: Association of low red blood cell folate concentrations with coronary artery disease in Iranians: a matched case-control study.
Journal: Journal of vascular research 20050101
Title: Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: the Nuheal trial.
Journal: Advances in experimental medicine and biology 20050101
Title: Natural history of S-adenosylmethionine-binding proteins.
Journal: BMC structural biology 20050101
Title: A mathematical model of the folate cycle: new insights into folate homeostasis.
Journal: The Journal of biological chemistry 20041231
Title: Implications of beta-mercaptoethanol in relation to folate stability and to determination of folate degradation kinetics during processing: a case study on [6S]-5-methyltetrahydrofolic acid.
Journal: Journal of agricultural and food chemistry 20041229
Title: Cerebral folate deficiency.
Journal: Developmental medicine and child neurology 20041201
Title: Homocysteine: exploring its potential as a pharmacodynamic biomarker of antifolate chemotherapy.
Journal: Pharmacogenomics 20041201
Title: MTHFR polymorphisms and risk of chronic lymphocytic leukemia.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20041201
Title: Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.
Journal: Pharmacogenetics 20041201
Title: New approach for the identification of folate-related pathways in human embryogenesis.
Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20041201
Title: Polymorphisms in the methylenetetrahydrofolate reductase gene and prostate cancer risk.
Journal: International journal of oncology 20041101
Title: Folate, DNA stability and colo-rectal neoplasia.
Journal: The Proceedings of the Nutrition Society 20041101
Title: Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate.
Journal: The Journal of biological chemistry 20041022
Title: Metabolism of homocysteine and its relationship with cardiovascular disease.
Journal: Journal of thrombosis and thrombolysis 20041001
Title: Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency.
Journal: The Biochemical journal 20040915
Title: Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040901
Title: Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040901
Title: Chemopreventive role of folic acid in colorectal cancer.
Journal: Frontiers in bioscience : a journal and virtual library 20040901
Title: Folate deficiency induces aneuploidy in human lymphocytes in vitro-evidence using cytokinesis-blocked cells and probes specific for chromosomes 17 and 21.
Journal: Mutation research 20040713
Title: Placental folate transport and binding are not impaired in pregnancies complicated by fetal growth restriction.
Journal: Placenta 20040701
Title: Effect of folic Acid supplementation on the folate status of buccal mucosa and lymphocytes.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040701
Title: Mutations of the MTHFR gene (428C>T and [458G>T+459C>T]) markedly decrease MTHFR enzyme activity.
Journal: Neurogenetics 20040601
Title: Methionine metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can import S-adenosylmethionine from the cytosol.
Journal: The Journal of biological chemistry 20040521
Title: The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma.
Journal: British journal of cancer 20040517
Title: A review of folate receptor alpha cycling and 5-methyltetrahydrofolate accumulation with an emphasis on cell models in vitro.
Journal: Advanced drug delivery reviews 20040429
Title: Quantitative evaluation of the drug-drug interactions between methotrexate and nonsteroidal anti-inflammatory drugs in the renal uptake process based on the contribution of organic anion transporters and reduced folate carrier.
Journal: The Journal of pharmacology and experimental therapeutics 20040401
Title: The C677 mutation in methylene tetrahydrofolate reductase gene: correlation with uric acid and cardiovascular risk factors in elderly Korean men.
Journal: Journal of Korean medical science 20040401
Title: Hyperproliferation of homocysteine-treated colon cancer cells is reversed by folate and 5-methyltetrahydrofolate.
Journal: European journal of nutrition 20040401
Title: 5-Methyltetrahydrofolic acid and folic acid measured in plasma with liquid chromatography tandem mass spectrometry: applications to folate absorption and metabolism.
Journal: Analytical biochemistry 20040315
Title: Sodium-dependent methotrexate carrier-1 is expressed in rat kidney: cloning and functional characterization.
Journal: American journal of physiology. Renal physiology 20040301
Title: Folic acid rescues nitric oxide-induced neural tube closure defects.
Journal: Cell death and differentiation 20040301
Title: Pharmacokinetic study on the utilisation of 5-methyltetrahydrofolate and folic acid in patients with coronary artery disease.
Journal: British journal of pharmacology 20040301
Title: Comparative study on pressure and temperature stability of 5-methyltetrahydrofolic acid in model systems and in food products.
Journal: Journal of agricultural and food chemistry 20040211
Title: Determination of folate vitamers in human serum by stable-isotope-dilution tandem mass spectrometry and comparison with radioassay and microbiologic assay.
Journal: Clinical chemistry 20040201
Title: Solid-phase extraction-electrospray ionization mass spectrometry for the quantification of folate in human plasma or serum.
Journal: Analytical biochemistry 20040201
Title: Folate, homocysteine, endothelial function and cardiovascular disease.
Journal: The Journal of nutritional biochemistry 20040201
Title: Normal dopaminergic and serotonergic metabolites in cerebrospinal fluid and blood of restless legs syndrome patients.
Journal: Movement disorders : official journal of the Movement Disorder Society 20040201
Title: Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity.
Journal: British journal of cancer 20040126
Title: Red cell N5-methyltetrahydrofolate concentrations and C677T methylenetetrahydrofolate reductase genotype in patients with stroke.
Journal: Journal of clinical pathology 20040101
Title: Methylenetetrahydrofolate reductase and transcobalamin genetic polymorphisms in human spontaneous abortion: biological and clinical implications.
Journal: Reproductive biology and endocrinology : RB&E 20040101
Title: Homocysteine and reactive oxygen species in metabolic syndrome, type 2 diabetes mellitus, and atheroscleropathy: the pleiotropic effects of folate supplementation.
Journal: Nutrition journal 20040101
Title: Homocysteine increases methionine synthase mRNA level in Caco-2 cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101
Title: MTHFR C677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinson's disease.
Journal: Journal of neural transmission. Supplementum 20040101
Title: Effect of pH on temperature stability of folates.
Journal: Communications in agricultural and applied biological sciences 20040101
Title: Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore.
Journal: FEBS letters 20031218
Title: Cobalamin-dependent methionine synthase: probing the role of the axial base in catalysis of methyl transfer between methyltetrahydrofolate and exogenous cob(I)alamin or cob(I)inamide.
Journal: Biochemistry 20031216
Title: Dietary prevention of post-angioplasty restenosis. From illusion and disillusion to pragmatism.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20031201
Title: Hyperhomocystinemia in children with inflammatory bowel disease.
Journal: Journal of pediatric gastroenterology and nutrition 20031101
Title: Age dependence of the influence of methylenetetrahydrofolate reductase genotype on plasma homocysteine level.
Journal: American journal of epidemiology 20031101
Title: Folate improves endothelial function in patients with coronary heart disease.
Journal: Clinical chemistry and laboratory medicine 20031101
Title: Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae.
Journal: The Journal of biological chemistry 20031031
Title: Characterization of a pseudogene for murine methylenetetrahydrofolate reductase.
Journal: Molecular and cellular biochemistry 20031001
Title: Cerebrospinal fluid pterins and folates in Aicardi-Goutières syndrome: a new phenotype.
Journal: Neurology 20030909
Title: Reduced folate transport to the CNS in female Rett patients.
Journal: Neurology 20030826
Title: Uptake of 5-methyltetrahydrofolate into PC-3 human prostate cancer cells is carrier-mediated.
Journal: The Journal of nutritional biochemistry 20030801
Title: Antisense modulation of the coding or regulatory sequence of the folate receptor (folate binding protein-1) in mouse embryos leads to neural tube defects.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20030701
Title: Residues 45 and 404 in the murine reduced folate carrier may interact to alter carrier binding and mobility.
Journal: Biochimica et biophysica acta 20030627
Title: A mass spectrometric validated high-performance liquid chromatography procedure for the determination of folates in foods.
Journal: Journal of agricultural and food chemistry 20030618
Title: Analysis of the human folate receptor beta gene for an association with neural tube defects.
Journal: Molecular genetics and metabolism 20030601
Title: Model studies on the stability of folic acid and 5-methyltetrahydrofolic acid degradation during thermal treatment in combination with high hydrostatic pressure.
Journal: Journal of agricultural and food chemistry 20030521
Title: Characterization of mutations in severe methylenetetrahydrofolate reductase deficiency reveals an FAD-responsive mutation.
Journal: Human mutation 20030501
Title: Specific and sensitive quantification of folate vitamers in foods by stable isotope dilution assays using high-performance liquid chromatography-tandem mass spectrometry.
Journal: Analytical and bioanalytical chemistry 20030501
Title: Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030501
Title: Does the interaction between maternal folate intake and the methylenetetrahydrofolate reductase polymorphisms affect the risk of cleft lip with or without cleft palate?
Journal: American journal of epidemiology 20030401
Title: Determination of 5-methyltetrahydrofolic acid and folic acid in citrus juices using stable isotope dilution-mass spectrometry.
Journal: Journal of agricultural and food chemistry 20030226
Title: Transport of 5-formyltetrahydrofolate into primary cultured cerebellar granule cells.
Journal: Brain research 20030207
Title: Transport of 5-formyltetrahydrofolate into primary cultured rat astrocytes.
Journal: Archives of biochemistry and biophysics 20030201
Title: Effect of riboflavin status on the homocysteine-lowering effect of folate in relation to the MTHFR (C677T) genotype.
Journal: Clinical chemistry 20030201
Title: Affinity extraction combined with stable isotope dilution LC/MS for the determination of 5-methyltetrahydrofolate in human plasma.
Journal: Analytical biochemistry 20030201
Title: A method for the analysis of natural and synthetic folate in foods.
Journal: Journal of agricultural and food chemistry 20030115
Title: A comparison of folic acid and 5-methyltetrahydrofolate for prevention of DNA damage and cell death in human lymphocytes in vitro.
Journal: Mutagenesis 20030101
Title: Thrombophilia and pregnancy.
Journal: Reproductive biology and endocrinology : RB&E 20030101
Title: Distribution of plasma folate forms in hemodialysis patients receiving high daily doses of L-folinic or folic acid.
Journal: Kidney international 20021201
Title: Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20021201
Title: Monitoring of methotrexate and reduced folates in the cerebrospinal fluid of cancer patients.
Journal: International journal of clinical pharmacology and therapeutics 20021201
Title: Psychomotor retardation, spastic paraplegia, cerebellar ataxia and dyskinesia associated with low 5-methyltetrahydrofolate in cerebrospinal fluid: a novel neurometabolic condition responding to folinic acid substitution.
Journal: Neuropediatrics 20021201
Title: Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses.
Journal: The Journal of biological chemistry 20021011
Title: Measurement of red blood cell methylfolate.
Journal: Lancet (London, England) 20020928
Title: The enrichment of eggs with folic acid through supplementation of the laying hen diet.
Journal: Poultry science 20020901
Title: Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms.
Journal: Mammalian genome : official journal of the International Mammalian Genome Society 20020901
Title: Effect of low doses of 5-methyltetrahydrofolate and folic acid on plasma homocysteine in healthy subjects with or without the 677C-->T polymorphism of methylenetetrahydrofolate reductase.
Journal: European journal of clinical investigation 20020901
Title: Syntheses of labeled vitamers of folic acid to be used as internal standards in stable isotope dilution assays.
Journal: Journal of agricultural and food chemistry 20020814
Title: Antisense inhibition of methylenetetrahydrofolate reductase reduces survival of methionine-dependent tumour lines.
Journal: British journal of cancer 20020715
Title: Nature and nurture in vitamin B12 deficiency.
Journal: Archives of disease in childhood 20020701
Title: Impaired NO-dependent vasodilation in patients with Type II (non-insulin-dependent) diabetes mellitus is restored by acute administration of folate.
Journal: Diabetologia 20020701
Title: Determination of 5-methyltetrahydrofolate (13C-labeled and unlabeled) in human plasma and urine by combined liquid chromatography mass spectrometry.
Journal: Analytical biochemistry 20020615
Title: Interaction of 5-methyltetrahydrofolate and tetrahydrobiopterin on endothelial function.
Journal: American journal of physiology. Heart and circulatory physiology 20020601
Title: The C677T mutation in the methylenetetrahydrofolate reductase gene contributes to hyperhomocysteinemia in patients taking anticonvulsants.
Journal: Brain & development 20020601
Title: 5,10-Methylenetetrahydrofolate reductase (MTHFR) assay in the forward direction: residual activity in MTHFR deficiency.
Journal: Clinical chemistry 20020601
Title: 5-methyltetrahydrofolate restores endothelial function in uraemic patients on convective haemodialysis.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020501
Title: Role of the C-terminus and the long cytoplasmic loop in reduced folate carrier expression and function.
Journal: Biochemical pharmacology 20020501
Title: Vitamin C therapy ameliorates vascular endothelial dysfunction in treated patients with homocystinuria.
Journal: Journal of inherited metabolic disease 20020501
Title: Red blood cell methylfolate and plasma homocysteine as risk factors for venous thromboembolism: a matched case-control study.
Journal: Lancet (London, England) 20020302
Title: Downregulation of reduced-folate transporter by glucose in cultured RPE cells and in RPE of diabetic mice.
Journal: Investigative ophthalmology & visual science 20020201
Title: Rapid method for the determination of total 5-methyltetrahydrofolate in blood by liquid chromatography with fluorescence detection.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020125
Title: Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering.
Journal: Circulation 20020101
Title: Intimal redox stress: accelerated atherosclerosis in metabolic syndrome and type 2 diabetes mellitus. Atheroscleropathy.
Journal: Cardiovascular diabetology 20020101
Title: Methylenetetrahydrofolate reductase polymorphism and susceptibility to breast cancer.
Journal: Breast cancer research : BCR 20020101
Title: Assays of methylenetetrahydrofolate reductase and methionine synthase activities by monitoring 5-methyltetrahydrofolate and tetrahydrofolate using high-performance liquid chromatography with fluorescence detection.
Journal: Analytical biochemistry 20011215
Title: Folate protects against oxidative modification of human LDL.
Journal: The British journal of nutrition 20011201
Title: Association of methylenetetrahydrofolate reductase polymorphism C677T and dietary folate with the risk of cervical dysplasia.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20011201
Title: Binding of radiolabeled folate and 5-methyltetrahydrofolate to cow's milk folate binding protein at pH 7.4 and 5.0. Relationship to concentration and polymerization equilibrium of the purified protein.
Journal: Bioscience reports 20011201
Title: Carrier-mediated transport of folic acid in BeWo cell monolayers as a model of the human trophoblast.
Journal: Placenta 20011101
Title: High-performance liquid chromatographic measurement of 5,10-methylenetetrahydrofolate in liver.
Journal: Analytical biochemistry 20011015
Title: Treatment of hyperhomocysteinemia in end-stage renal disease.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
Title: Folic-acid-mediated inhibition of human colon-cancer cell growth.
Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20010901
Title: Determination of folates in foods by high-performance liquid chromatography with fluorescence detection after precolumn conversion to 5-methyltetrahydrofolates.
Journal: Journal of chromatography. A 20010831
Title: Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide?
Journal: Arteriosclerosis, thrombosis, and vascular biology 20010701
Title: A novel neurodevelopmental syndrome responsive to 5-hydroxytryptophan and carbidopa.
Journal: Molecular genetics and metabolism 20010601
Title: Effect of feeding on circulating micronutrient concentrations in the Burmese python (Python molurus).
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010601
Title: Marked suppression of the activity of some, but not all, antifolate compounds by augmentation of folate cofactor pools within tumor cells.
Journal: Biochemical pharmacology 20010401
Title: Methylenetetrahydrofolate reductase 677 C/T genotype and cardiovascular disease mortality in postmenopausal women.
Journal: American journal of epidemiology 20010401
Title: Comparison of dihydrofolate reductase activities for folic acid in pigs and rats using in vivo and in vitro evaluation techniques.
Journal: Journal of nutritional science and vitaminology 20010401
Title: Enzymatic determination of homocysteine in cell extracts.
Journal: Analytical biochemistry 20010301
Title: Effect of food on the oral bioavailability of UFT and leucovorin in cancer patients.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010301
Title: Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction.
Journal: Atherosclerosis 20010215
Title: Treatment of hyperhomocysteinemia in hemodialysis patients and renal transplant recipients.
Journal: Kidney international. Supplement 20010201
Title: Low seminal plasma folate concentrations are associated with low sperm density and count in male smokers and nonsmokers.
Journal: Fertility and sterility 20010201
Title: Antisense modulation of 5,10-methylenetetrahydrofolate reductase expression produces neural tube defects in mouse embryos.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20010101
Title: Folate and chemoprevention of colorectal cancer: Is 5-methyl-tetrahydrofolate an active antiproliferative agent in folate-treated colon-cancer cells?
Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20010101
Title: Plasma folate, vitamin B(12), and total homocysteine and homozygosity for the C677T mutation of the 5,10-methylene tetrahydrofolate reductase gene in patients with Alzheimer's dementia. A case-control study.
Journal: Gerontology 20010101
Title: Serum folate levels after UVA exposure: a two-group parallel randomised controlled trial.
Journal: BMC dermatology 20010101
Title: Manisha Prajapat, et al. Virtual screening and molecular dynamics study of approved drugs as inhibitors of spike protein S1 domain and ACE2 interaction in SARS-CoV-2. J Mol Graph Model. 2020 Dec;101:107716.
Title: Maša Vidmar Golja, et al. Simultaneous quantification of intracellular concentrations of clinically important metabolites of folate-homocysteine cycle by LC-MS/MS. Anal Biochem. 2020 Sep 15;605:113830.