Home Aldehydes 2144-08-3
2144-08-3,MFCD00003325
Catalog No.:AA003B0S

2144-08-3 | 2,3,4-Trihydroxybenzaldehyde

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1g
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$7.00   $5.00
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10g
98%
in stock  
$11.00   $8.00
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25g
98%
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$17.00   $12.00
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100g
98%
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$62.00   $43.00
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500g
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$258.00   $181.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003B0S
Chemical Name:
2,3,4-Trihydroxybenzaldehyde
CAS Number:
2144-08-3
Molecular Formula:
C7H6O4
Molecular Weight:
154.1201
MDL Number:
MFCD00003325
SMILES:
O=Cc1ccc(c(c1O)O)O
NSC Number:
22595
Properties
Properties
 
BP:
301.9°C at 760 mmHg  
Form:
Solid  
MP:
159-161 °C(lit.)  
Refractive Index:
1.6400 (estimate)  
Stability:
Air Sensitive  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
147  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
0.9  

Upstream Synthesis Route

[1]Molecules,2013,vol.18,#12,p.15613-15623

[2]Chemistry-AEuropeanJournal,2017,vol.23,#45,p.10800-10807

[1]OrganicandBiomolecularChemistry,2014,vol.12,#22,p.3721-3734

[2]Molecules,2015,vol.20,#5,p.9229-9241

[3]JustusLiebigsAnnalenderChemie,1972,vol.763,p.109-120

[1]BioorganicandMedicinalChemistry,2014,vol.22,#9,p.2671-2677

[1]ChemischeBerichte,1898,vol.31,p.1768

[2]JustusLiebigsAnnalenderChemie,1907,vol.357,p.373

[3]ChemischeBerichte,1899,vol.32,p.279

[4]GazzettaChimicaItaliana,1925,vol.55,p.673,677

[5]JournaloftheAmericanChemicalSociety,1923,vol.45,p.2377

[1]ChemischeBerichte,1901,vol.34,p.1443

[2]Patent:DE114195,,,

[3]Patent:DE114195,,,

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartKumar,BVinay;Naik,HalehattyS.Bhojya;Girija;Kumar,BVijaya[JournalofChemicalSciences,2011,vol.123,#5,p.615-621]

[2]Locationinpatent:experimentalpartValizadeh;Azimi[JournaloftheIranianChemicalSociety,2011,vol.8,#1,p.123-130]

[3]Girija;Naik,H.S.Bhojya;Kumar,B.Vinay;Sudhamani;Harish[LettersinOrganicChemistry,2013,vol.10,#7,p.468-477]

[4]Locationinpatent:experimentalpartValizadeh,Hassan;Gholipour,Hamid[SyntheticCommunications,2010,vol.40,#10,p.1477-1485]

[5]Wang,Ping;Xia,Yang-Liu;Zou,Li-Wei;Qian,Xing-Kai;Dou,Tong-Yi;Jin,Qiang;Li,Shi-Yang;Yu,Yang;Wang,Dan-Dan;Luo,Qun;Ge,Guang-Bo;Yang,Ling[Chemistry-AEuropeanJournal,2017,vol.23,#45,p.10800-10807]

[6]Xia,Yangliu;Chen,Chen;Liu,Yong;Ge,Guangbo;Dou,Tongyi;Wang,Ping[Molecules,2018,vol.23,#10]

[7]Locationinpatent:experimentalpartValizadeh,Hassan;Vaghefi,Sevil[SyntheticCommunications,2009,vol.39,#9,p.1666-1678]

[8]Labey[AnnalesPharmaceutiquesFrancaises,1949,vol.7,p.439]

[9]Boehm[ArchivderPharmazie,1933,vol.271,p.490,502]

[1]Saito,Shizuka;Kawabata,Jun[Tetrahedron,2005,vol.61,#34,p.8101-8108]

[2]Wang,Zengtao;Liu,Zhiguo;Cao,Yongkai;Paudel,Suresh;Yoon,Goo;Cheon,SeungHoon[BulletinoftheKoreanChemicalSociety,2013,vol.34,#12,p.3906-3908]

[3]Xu,Jimin;Ai,Jing;Liu,Sheng;Peng,Xia;Yu,Linqian;Geng,Meiyu;Nan,Fajun[OrganicandBiomolecularChemistry,2014,vol.12,#22,p.3721-3734]

[4]Islam,Azizul;Khan,SaeedAhmad;Krishnamurti,M.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1982,vol.21,#10,p.965-966]

[1]Xu,Jimin;Ai,Jing;Liu,Sheng;Peng,Xia;Yu,Linqian;Geng,Meiyu;Nan,Fajun[OrganicandBiomolecularChemistry,2014,vol.12,#22,p.3721-3734]

[2]Casanova,BrunaB.;Muniz,MauroN.;DeOliveira,Thayse;DeOliveira,LuísFlavio;Machado,MichelM.;Fuentefria,AlexandreM.;Gosmann,Grace;Gnoatto,SimoneC.B.[Molecules,2015,vol.20,#5,p.9229-9241]

[3]Sugihara;Watanabe;Kawamatsu;Morimoto[JustusLiebigsAnnalenderChemie,1972,vol.763,p.109-120]

[1]CurrentPatentAssignee:TIANJINUNIVERSITY-CN105753892,2016,ALocationinpatent:Paragraph0070;0071;0072

[2]Achalkumar,AmmathnaduS.;Veerabhadraswamy;Hiremath,UmaS.;Rao,DoddamaneS.Shankar;Prasad,SubbaraoKrishna;Yelamaggad,ChannabasaveshwarV.[DyesandPigments,2016,vol.132,p.291-305]

[3]Donnio,Bertrand;Bruce,DuncanW.[JournaloftheChemicalSociety,DaltonTransactions,1997,#16,p.2745-2755]

[4]Singh,HemantKumar;Singh,SachinKumar;Nandi,Rajib;Singh,MadanKumar;Kumar,Vijay;Singh,RanjanK.;Rao,D.S.Shankar;Prasad,S.Krishna;Singh,Bachcha[RSCAdvances,2015,vol.5,#55,p.44274-44281]

[5]Shanker;Bindushree;Chaithra;Pratap;Gupta,RavindraKumar;Achalkumar;Yelamaggad[JournalofMolecularLiquids,2019,vol.275,p.849-858]

[6]Kanth,Priyanka;Singh,HemantKumar;Kumar,Vijay;Singh,SachinKumar;Rao,D.S.Shankar;Prasad,S.Krishna;Singh,Bachcha[JournalofMolecularLiquids,2019,vol.289]

[1]Forschner,Robert;Knelles,Jakob;Bader,Korinna;Müller,Carsten;Frey,Wolfgang;Köhn,Andreas;Molard,Yann;Giesselmann,Frank;Laschat,Sabine[Chemistry-AEuropeanJournal,2019,vol.25,#56,p.12966-12980]

[2]CurrentPatentAssignee:TIANJINUNIVERSITY-CN105753892,2016,ALocationinpatent:Paragraph0083;0084;0085

[3]Vinayakumara;Swamynathan;Kumar,Sandeep;Adhikari,AirodyVasudeva[NewJournalofChemistry,2019,vol.43,#18,p.7099-7108]

[4]Shanker;Prehm;Yelamaggad;Tschierske[JournalofMaterialsChemistry,2011,vol.21,#14,p.5307-5311]

[5]Achalkumar,AmmathnaduS.;Veerabhadraswamy;Hiremath,UmaS.;Rao,DoddamaneS.Shankar;Prasad,SubbaraoKrishna;Yelamaggad,ChannabasaveshwarV.[DyesandPigments,2016,vol.132,p.291-305]

[6]Veerabhadraswamy;Bhat,SachinA.;Hiremath,UmaS.;Yelamaggad,ChannabasaveshwarV.[ChemPhysChem,2019,vol.20,#21,p.2836-2851]

[7]Vinayakumara;Kumar,Sandeep;Adhikari,AirodyVasudeva[JournalofMolecularLiquids,2019,vol.274,p.215-222]

[8]Donnio,Bertrand;Bruce,DuncanW.[JournaloftheChemicalSociety,DaltonTransactions,1997,#16,p.2745-2755]

[9]Singh,HemantKumar;Singh,SachinKumar;Nandi,Rajib;Singh,MadanKumar;Kumar,Vijay;Singh,RanjanK.;Rao,D.S.Shankar;Prasad,S.Krishna;Singh,Bachcha[RSCAdvances,2015,vol.5,#55,p.44274-44281]

[10]Shanker;Bindushree;Chaithra;Pratap;Gupta,RavindraKumar;Achalkumar;Yelamaggad[JournalofMolecularLiquids,2019,vol.275,p.849-858]

[11]Kanth,Priyanka;Singh,HemantKumar;Kumar,Vijay;Singh,SachinKumar;Rao,D.S.Shankar;Prasad,S.Krishna;Singh,Bachcha[JournalofMolecularLiquids,2019,vol.289]

Literature

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Title: Medicinal chemistry as a conduit for the modulation of quorum sensing.

Journal: Journal of medicinal chemistry 20101111

Title: (E)-N'-(2,3,4-Trihy-droxy-benzyl-idene)-isonicotinohydrazide dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: The severity of Puumala hantavirus induced nephropathia epidemica can be better evaluated using plasma interleukin-6 than C-reactive protein determinations.

Journal: BMC infectious diseases 20100101

Title: Impact of linker strain and flexibility in the design of a fragment-based inhibitor.

Journal: Nature chemical biology 20090601

Title: 2,3,4-Trihydroxy-benzaldehyde.

Journal: Acta crystallographica. Section E, Structure reports online 20080801

Title: Pyrogallol and its analogs can antagonize bacterial quorum sensing in Vibrio harveyi.

Journal: Bioorganic & medicinal chemistry letters 20080301

Title: Carbohydrazones of substituted salicylaldehydes as potential lead compounds for the development of narrow-spectrum antimicrobials.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

Title: Self-activating nuclease activity of copper (II) complexes of hydroxyl-rich ligands.

Journal: Journal of inorganic biochemistry 20060101

Title: alpha-Glucosidase inhibition of 6-hydroxyflavones. Part 3: Synthesis and evaluation of 2,3,4-trihydroxybenzoyl-containing flavonoid analogs and 6-aminoflavones as alpha-glucosidase inhibitors.

Journal: Bioorganic & medicinal chemistry 20050301

Title: New non-nucleoside inhibitors of hepatitis C virus RNA-dependent RNA polymerase.

Journal: Biochemistry. Biokhimiia 20040701

Title: Antibacterial activities of phenolic benzaldehydes and benzoic acids against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, and Salmonella enterica.

Journal: Journal of food protection 20031001

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SDS
Tags:2144-08-3 Molecular Formula|2144-08-3 MDL|2144-08-3 SMILES|2144-08-3 2,3,4-Trihydroxybenzaldehyde |Organic_Building_Blocks