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5560-59-8,MFCD00035086
Catalog No.:AA003NQQ

5560-59-8 | Alverine citrate

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Purity
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Price(USD)
Quantity
  
1g
95%
in stock  
$18.00   $13.00
- +
5g
95%
in stock  
$56.00   $39.00
- +
25g
95%
in stock  
$231.00   $162.00
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100g
95%
in stock  
$691.00   $484.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003NQQ
Chemical Name:
Alverine citrate
CAS Number:
5560-59-8
Molecular Formula:
C26H35NO7
Molecular Weight:
473.5586
MDL Number:
MFCD00035086
SMILES:
OC(=O)CC(C(=O)O)(CC(=O)O)O.CCN(CCCc1ccccc1)CCCc1ccccc1
Properties
Properties
 
BP:
358.8°C at 760 mmHg  
Form:
Solid  
MP:
101-105°C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
442  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
14  

Literature

Title: Inclusion of a spasmolytic in bowel cleansing: a prospective randomized study.

Journal: Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: A rapid and most sensitive liquid chromatography/tandem mass spectrometry method for simultaneous determination of alverine and its major metabolite, para hydroxy alverine, in human plasma: application to a pharmacokinetic and bioequivalence study.

Journal: Drug testing and analysis 20100601

Title: Alverine citrate, simeticone, and Rome III irritable bowel syndrome.

Journal: Alimentary pharmacology & therapeutics 20100401

Title: Clinical trial: the efficacy of alverine citrate/simeticone combination on abdominal pain/discomfort in irritable bowel syndrome--a randomized, double-blind, placebo-controlled study.

Journal: Alimentary pharmacology & therapeutics 20100301

Title: [A case report of alverine-citrate-induced acute hepatitis].

Journal: The Korean journal of hepatology 20100301

Title: Spasmolytic and anti-inflammatory effects of constituents from Hertia cheirifolia.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20091201

Title: Dyclonine and alverine citrate enhance the cytotoxic effects of proteasome inhibitor MG132 on breast cancer cells.

Journal: International journal of molecular medicine 20090201

Title: Validated LC-MS/MS method for determination of Alverine and one of its hydroxy metabolites in human plasma along with its application to a bioequivalence study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115

Title: Alverine citrate plus simethicone reduces cecal intubation time in colonoscopy - a randomized study.

Journal: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20080901

Title: Evolving mechanisms of action of alverine citrate on phasic smooth muscles.

Journal: British journal of pharmacology 20071201

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: [Dynamics of clinical symptoms and indices of visceral sensitivity in patients with the irritated bowels syndrome treated with meteospasmyl].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20050101

Title: Alverine citrate induced acute hepatitis.

Journal: World journal of gastroenterology 20040801

Title: Alverine citrate fails to relieve the symptoms of irritable bowel syndrome: results of a double-blind, randomized, placebo-controlled trial.

Journal: Alimentary pharmacology & therapeutics 20020601

Title: Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype.

Journal: The Journal of pharmacy and pharmacology 20011001

Title: Effects of alverine citrate on cat intestinal mechanoreceptor responses to chemical and mechanical stimuli.

Journal: Alimentary pharmacology & therapeutics 19990401

Title: Acute hepatitis caused by alverine associated with anti-lamin A and C autoantibodies.

Journal: Journal of hepatology 19970801

Title: Effects of alverine on the spontaneous electrical activity and nervous control of the proximal colon of the rabbit.

Journal: Gastroenterologie clinique et biologique 19920101

Title: Coelho, A.M., et al., Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype. J Pharm Pharmacol, 2001. 53(10): p. 1419-26.

Title: Hayase, M., et al., Evolving mechanisms of action of alverine citrate on phasic smooth muscles. Br J Pharmacol, 2007. 152(8): p. 1228-38.

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