Title: 5-Bromo-phthalazine hemihydrate.
Journal: Acta crystallographica. Section E, Structure reports online 20120801
Title: 1-(2,6-Diisopropyl-phen-oxy)-4-phenyl-phthalazine.
Journal: Acta crystallographica. Section E, Structure reports online 20120801
Title: Ultrasound-promoted one-pot, three-component synthesis of spiro[indoline-3,1'-pyrazolo[1,2-b]phthalazine] derivatives.
Journal: Molecules (Basel, Switzerland) 20120723
Title: Reactions of phthalazine, quinazoline, 4,7-phenanthroline and 2,3'-bipyridine with ruthenium carbonyl.
Journal: Dalton transactions (Cambridge, England : 2003) 20120628
Title: Synthesis, vasorelaxant activity, and molecular modeling study of some new phthalazine derivatives.
Journal: European journal of medicinal chemistry 20120601
Title: Ultrasound-promoted catalyst-free one-pot four component synthesis of 2H-indazolo[2,1-b]phthalazine-triones in neutral ionic liquid 1-butyl-3-methylimidazolium bromide.
Journal: Ultrasonics sonochemistry 20120301
Title: Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons.
Journal: The Journal of biological chemistry 20120217
Title: In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against Leishmania infantum and Leishmania braziliensis species.
Journal: The Journal of antimicrobial chemotherapy 20120201
Title: A practical and direct comparison of intrinsic metabolic clearance of several non-CYP enzyme substrates in freshly isolated and cryopreserved hepatocytes.
Journal: Drug metabolism and pharmacokinetics 20120101
Title: A catalytically silent FAAH-1 variant drives anandamide transport in neurons.
Journal: Nature neuroscience 20120101
Title: Flavonoid glycosides isolated from unique legume plant extracts as novel inhibitors of xanthine oxidase.
Journal: PloS one 20120101
Title: Some recent approaches of biologically active substituted pyridazine and phthalazine drugs.
Journal: Current medicinal chemistry 20120101
Title: Inhibition of human liver aldehyde oxidase: implications for potential drug-drug interactions.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20111201
Title: 1-Benzoyl-4-(4-methyl-phen-yl)phthal-azine.
Journal: Acta crystallographica. Section E, Structure reports online 20111201
Title: Hydrogen-bonded structures of the isomeric compounds of phthalazine with 3-chloro-2-nitrobenzoic acid, 4-chloro-2-nitrobenzoic acid and 4-chloro-3-nitrobenzoic acid.
Journal: Acta crystallographica. Section C, Crystal structure communications 20111101
Title: Luminescent square-planar platinum(II) complexes with tridentate 3-bis(2-pyridylimino)isoindoline and monodentate N-heterocyclic ligands.
Journal: Dalton transactions (Cambridge, England : 2003) 20110714
Title: Transition metal complexes of the novel hexadentate ligand 1,4-bis(di(N-methylimidazol-2-yl)methyl)phthalazine.
Journal: Dalton transactions (Cambridge, England : 2003) 20110428
Title: Fourier transform microwave and millimeter wave spectroscopy of quinazoline, quinoxaline, and phthalazine.
Journal: The Journal of chemical physics 20110421
Title: The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis.
Journal: Journal of medicinal chemistry 20110414
Title: (S)-2-Amino-2-(2-chloro-phen-yl)cyclo-hexa-none.
Journal: Acta crystallographica. Section E, Structure reports online 20110401
Title: Biotransformation of quinazoline and phthalazine by Aspergillus niger.
Journal: Journal of bioscience and bioengineering 20110301
Title: Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase.
Journal: Journal of medicinal chemistry 20110113
Title: Design and synthesis of selective and potent orally active S1P5 agonists.
Journal: ChemMedChem 20101004
Title: Augmentation of the antileukemia potency of total-body irradiation (TBI) by a novel P-site inhibitor of spleen tyrosine kinase (SYK).
Journal: Radiation research 20101001
Title: Associative and dissociative mechanisms in the formation of phthalazine bridged organodiplatinum(II) complexes.
Journal: Inorganic chemistry 20100920
Title: Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor.
Journal: Journal of medicinal chemistry 20100909
Title: Synthesis and antitumor activities of novel 1,4-disubstituted phthalazine derivatives.
Journal: European journal of medicinal chemistry 20100801
Title: Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines.
Journal: Bioorganic & medicinal chemistry letters 20100801
Title: 2-[1-(3-Oxo-1,3-dihydro-2-benzofuran-1-yl)-1H-benzimidazol-2-yl]benzoic acid methanol solvate.
Journal: Acta crystallographica. Section E, Structure reports online 20100801
Title: 4-Hydr-oxy-6-[(4-hydr-oxy-1-oxo-1,2-dihydro-phthalazin-6-yl)carbon-yl]phthalazin-1(2H)-one.
Journal: Acta crystallographica. Section E, Structure reports online 20091201
Title: Phthalocyanine-C60 fused conjugates exhibiting molecular orbital interactions depending on the solvent polarity.
Journal: Chemistry, an Asian journal 20091102
Title: Synthesis and antibacterial activity of some new heterocycles incorporating phthalazine.
Journal: European journal of medicinal chemistry 20091101
Title: 3-Methyl-1,2,4-triazolo[3,4-a]phthalazine monohydrate.
Journal: Acta crystallographica. Section E, Structure reports online 20091101
Title: Novel phthalazinyl derivatives: synthesis, antimycobacterial activities, and inhibition of Mycobacterium tuberculosis isocitrate lyase enzyme.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20090901
Title: Evaluation of solvent effects on protonation using NMR spectroscopy: implication in salt formation.
Journal: International journal of pharmaceutics 20090730
Title: Dichloridobis(phenanthridine-κN)zinc(II).
Journal: Acta crystallographica. Section E, Structure reports online 20090701
Title: Theoretical quest for photoconversion molecules having opposite directions of the electric dipole moment in S0 and S1 states.
Journal: The Journal of chemical physics 20090514
Title: 2-(3-Oxo-1,3-dihydro-isobenzofuran-1-yl)-phthalazin-1(2H)-one.
Journal: Acta crystallographica. Section E, Structure reports online 20090501
Title: S(N)(H) approach in the synthesis of nitronyl nitroxides.
Journal: The Journal of organic chemistry 20090403
Title: Ultrasound assisted reactions of steroid analogous of anticipated biological activities.
Journal: Ultrasonics sonochemistry 20090301
Title: Practical synthesis of a p38 MAP kinase inhibitor.
Journal: The Journal of organic chemistry 20090116
Title: Microwave assisted reactions of some azaheterocylic compounds.
Journal: Molecules (Basel, Switzerland) 20090115
Title: Site directed mutagenesis of amino acid residues at the active site of mouse aldehyde oxidase AOX1.
Journal: PloS one 20090101
Title: Development of improved models for phosphodiesterase-4 inhibitors with a multi-conformational structure-based QSAR method.
Journal: Current chemical genomics 20090101
Title: Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffold.
Journal: Journal of medicinal chemistry 20081023
Title: Structural basis for ligand recognition at the benzodiazepine binding site of GABAA alpha 3 receptor, and pharmacophore-based virtual screening approach.
Journal: Journal of molecular graphics & modelling 20081001
Title: Synthesis of 3,4-benzo-7-hydroxy-2,9-diazabicyclo[3.3.1]non-7-enes by cyclization of 1,3-bis(silyl enol ethers) with quinazolines.
Journal: Organic & biomolecular chemistry 20080821
Title: Multiple surface plasmon resonances and near-infrared field enhancement of gold nanowells.
Journal: Analytical chemistry 20080701
Title: A new class of luminescent tricarbonyl rhenium(I) complexes containing bridging 1,2-diazine ligands: electrochemical, photophysical, and computational characterization.
Journal: Inorganic chemistry 20080519
Title: Conformation-activity relationship on novel 4-pyridylmethylthio derivatives with antiangiogenic activity.
Journal: Bioorganic & medicinal chemistry letters 20080501
Title: N,N'-Bis(4-chloro-phen-yl)urea.
Journal: Acta crystallographica. Section E, Structure reports online 20080501
Title: Synthesis of 1-/2-substituted-[1,2,3]triazolo[4,5-g]phthalazine-4,9-diones and evaluation of their cytotoxicity and topoisomerase II inhibition.
Journal: Bioorganic & medicinal chemistry 20080415
Title: Role of phosphodiesterase 5 in synaptic plasticity and memory.
Journal: Neuropsychiatric disease and treatment 20080401
Title: 2-(2-Hydroxy-ethyl)phthalazin-1(2H)-one.
Journal: Acta crystallographica. Section E, Structure reports online 20080401
Title: (1R,2R)-4-Benzoyl-2-benzo-yloxy-1-phenyl-butyl imidazole-1-carboxyl-ate.
Journal: Acta crystallographica. Section E, Structure reports online 20080301
Title: (2S,4'R,5'R)-(E)-tert-Butyl 2-acetyl-2-(2-oxo-5-phenyl-1,3-dioxolan-4-ylmeth-yl)-5-phenyl-pent-4-enoate.
Journal: Acta crystallographica. Section E, Structure reports online 20080201
Title: A new structure-based QSAR method affords both descriptive and predictive models for phosphodiesterase-4 inhibitors.
Journal: Current chemical genomics 20080101
Title: Phthalazin-1(2H)-one-picric acid (1/1).
Journal: Acta crystallographica. Section E, Structure reports online 20080101
Title: Copper(I) cyanide networks: synthesis, luminescence behavior and thermal analysis. Part 1. Diimine ligands.
Journal: Inorganic chemistry 20071015
Title: Efficiency improvement for sulfated ash determination by usage of a microwave muffle furnace.
Journal: Journal of pharmaceutical and biomedical analysis 20070411
Title: [Synthesis and characterization of silver-intermediates in the development process of photothermographic material].
Journal: Guang pu xue yu guang pu fen xi = Guang pu 20070401
Title: 1,4-Bis(alkylamino)benzo[g]phthalazines able to form dinuclear complexes of Cu(II) which as free ligands behave as SOD inhibitors and show efficient in vitro activity against Trypanosoma cruzi.
Journal: Bioorganic & medicinal chemistry 20070301
Title: Luminescent hydrido-carbonyl clusters of rhenium containing bridging 1,2-diazine ligands.
Journal: Inorganic chemistry 20061225
Title: 4-(Azolylphenyl)-phthalazin-1-amines: Novel inhibitors of VEGF receptors I and II.
Journal: Chemical biology & drug design 20061201
Title: 1-(Azolyl)-4-(aryl)-phthalazines: novel potent inhibitors of VEGF receptors I and II.
Journal: Chemical biology & drug design 20061101
Title: A dinucleating ligand related to the beta-diketiminates.
Journal: Dalton transactions (Cambridge, England : 2003) 20060828
Title: Aqueous N-heterocyclization of primary amines and hydrazines with dihalides: microwave-assisted syntheses of N-azacycloalkanes, isoindole, pyrazole, pyrazolidine, and phthalazine derivatives.
Journal: The Journal of organic chemistry 20060106
Title: Evaluation of apoptosis-induction by newly synthesized phthalazine derivatives in breast cancer cell lines.
Journal: Asian Pacific journal of cancer prevention : APJCP 20060101
Title: Oxidative addition of methyl iodide to a new type of binuclear platinum(II) complex: a kinetic study.
Journal: Inorganic chemistry 20051114
Title: Arylphthalazines: identification of a new phthalazine chemotype as inhibitors of VEGFR kinase.
Journal: Bioorganic & medicinal chemistry letters 20051101
Title: Phthalazine PDE IV inhibitors: conformational study of some 6-methoxy-1,4-disubstituted derivatives.
Journal: Bioorganic & medicinal chemistry 20050715
Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.
Journal: Chemical research in toxicology 20050601
Title: VEGF receptor kinase inhibitors: phthalazines, anthranilamides and related structures.
Journal: Expert opinion on therapeutic patents 20050601
Title: Novel transient receptor potential vanilloid 1 receptor antagonists for the treatment of pain: structure-activity relationships for ureas with quinoline, isoquinoline, quinazoline, phthalazine, quinoxaline, and cinnoline moieties.
Journal: Journal of medicinal chemistry 20050210
Title: Synthesis and luminescence properties of lanthanide complexes incorporating a hydralazine-derived chromophore.
Journal: Dalton transactions (Cambridge, England : 2003) 20050107
Title: A novel three-component reaction designed by the combinatorial method: heteroarenes, isothiocyanates and isocyanides.
Journal: Molecular diversity 20050101
Title: Enzymatic catalysis of urea decomposition: elimination or hydrolysis?
Journal: Journal of the American Chemical Society 20040929
Title: Synthesis and cytotoxicity of 1-substituted 2-methyl-1H-imidazo[4,5-g]phthalazine-4,9-dione derivatives.
Journal: Bioorganic & medicinal chemistry 20040701
Title: Synthesis of 5-azaindolizine derivatives by the palladium-catalyzed intermolecular formal [3+2] cycloaddition of alkylidenecyclopropanes with 1,2-diazines.
Journal: The Journal of organic chemistry 20040430
Title: Realization of unusual ligand binding motifs in metalated container molecules: synthesis, structures, and magnetic properties of the complexes [(LMe)Ni2(mu-L')]n+ with L'=NO3-, NO2-, N3-, N2H4, pyridazine, phthalazine, pyrazolate, and benzoate.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20040402
Title: Synthesis and characterization of Cu(2)(I,I), Cu(2)(I,II), and Cu(2)(II,II) compounds supported by two phthalazine-based ligands: influence of a hydrophobic pocket.
Journal: Inorganic chemistry 20040308
Title: Human liver aldehyde oxidase: inhibition by 239 drugs.
Journal: Journal of clinical pharmacology 20040101
Title: Potent inhibition of human liver aldehyde oxidase by raloxifene.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040101
Title: Enzymatic oxidation of phthalazine with guinea pig liver aldehyde oxidase and liver slices: inhibition by isovanillin.
Journal: Acta biochimica Polonica 20040101
Title: Modeling the syn disposition of nitrogen donors at the active sites of carboxylate-bridged diiron enzymes. Enforcing dinuclearity and kinetic stability with a 1,2-diethynylbenzene-based ligand.
Journal: Inorganic chemistry 20031229
Title: Synthesis and structural characterization of 1-(D-glycosyloxy)phthalazines.
Journal: Carbohydrate research 20031031
Title: Comparative molecular field analysis (CoMFA) of phthalazine derivatives as phosphodiesterase IV inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20030804
Title: Structure of human aldose reductase holoenzyme in complex with statil: an approach to structure-based inhibitor design of the enzyme.
Journal: Proteins 20030201
Title: Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products.
Journal: Toxicology 20021227
Title: Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20021001
Title: Phthalazine PDE4 inhibitors. Part 3: the synthesis and in vitro evaluation of derivatives with a hydrogen bond acceptor.
Journal: Bioorganic & medicinal chemistry letters 20020107
Title: The reaction of fullerene C(60) with phthalazine: the mechanochemical solid-state reaction yielding a new C(60) dimer versus the liquid-phase reaction affording an open-cage fullerene.
Journal: The Journal of organic chemistry 20011102
Title: Quantitative study of the structural requirements of phthalazine/quinazoline derivatives for interaction with human liver aldehyde oxidase.
Journal: Chemical & pharmaceutical bulletin 20010901
Title: Phthalazine-based dinucleating ligands afford dinuclear centers often encountered in metalloenzyme active sites.
Journal: Inorganic chemistry 20010226
Title: Phthalazine PDE4 inhibitors. Part 2: the synthesis and biological evaluation of 6-methoxy-1,4-disubstituted derivatives.
Journal: Bioorganic & medicinal chemistry letters 20010108
