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Title: Mechanism of As2O3-Induced Action Potential Prolongation and Using hiPS-CMs to Evaluate the Rescue Efficacy of Drugs With Different Rescue Mechanism.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170801
Title: Observations on conducting whole-cell patch clamping of the hERG cardiac K(+) channel in pure human serum.
Journal: Journal of applied toxicology : JAT 20170401
Title: Why Can dl-Sotalol Prolong the QT Interval In Vivo Despite Its Weak Inhibitory Effect on hERG K(+) Channels In Vitro? Electrophysiological and Pharmacokinetic Analysis with the Halothane-Anesthetized Guinea Pig Model.
Journal: Cardiovascular toxicology 20160401
Title: H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20140715
Title: Availability of human induced pluripotent stem cell-derived cardiomyocytes in assessment of drug potential for QT prolongation.
Journal: Toxicology and applied pharmacology 20140701
Title: Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice.
Journal: PloS one 20140101
Title: Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131201
Title: Activity, inhibition, and induction of cytochrome P450 2J2 in adult human primary cardiomyocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20131201
Title: Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131201
Title: Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates.
Journal: Journal of applied toxicology : JAT 20121001
Title: Involvement of serine protease and proteinase-activated receptor 2 in dermatophyte-associated itch in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20121001
Title: H(1)-antihistamines and urticaria: how can we predict the best drug for our patient?
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20121001
Title: Negative electro-mechanical windows are required for drug-induced Torsades de Pointes in the anesthetized guinea pig.
Journal: Journal of pharmacological and toxicological methods 20120901
Title: Effect of intestinal first-pass hydrolysis on the oral bioavailability of an ester prodrug of fexofenadine.
Journal: Journal of pharmaceutical sciences 20120901
Title: Synthesis of betulinic acid derivatives as entry inhibitors against HIV-1 and bevirimat-resistant HIV-1 variants.
Journal: Bioorganic & medicinal chemistry letters 20120815
Title: Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling.
Journal: Journal of medicinal chemistry 20120809
Title: Quantification of fexofenadine in biological matrices: a review of bioanalytical methods.
Journal: Biomedical chromatography : BMC 20120801
Title: Exploring novel colon-targeting antihistaminic prodrug for colitis.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120801
Title: Cathepsin E induces itch-related response through the production of endothelin-1 in mice.
Journal: European journal of pharmacology 20120705
Title: Microdosing clinical study: pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit juice) profiles of celiprolol following the oral microdose and therapeutic dose.
Journal: Journal of clinical pharmacology 20120701
Title: Mouse model of touch-evoked itch (alloknesis).
Journal: The Journal of investigative dermatology 20120701
Title: Development of recombinant cell line co-expressing mutated Nav1.5, Kir2.1, and hERG for the safety assay of drug candidates.
Journal: Journal of biomolecular screening 20120701
Title: Enhanced systemic exposure of fexofenadine via the intranasal administration of chitosan-coated liposome.
Journal: International journal of pharmaceutics 20120701
Title: Long-lasting inhibition of the intestinal absorption of fexofenadine by cyclosporin A in rats.
Journal: Journal of pharmaceutical sciences 20120701
Title: Influence of Panax ginseng on cytochrome P450 (CYP)3A and P-glycoprotein (P-gp) activity in healthy participants.
Journal: Journal of clinical pharmacology 20120601
Title: The impact of P-glycoprotein mediated efflux on absorption of 11 sedating and less-sedating antihistamines using Caco-2 monolayers.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20120601
Title: Does terfenadine-induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes?
Journal: British journal of pharmacology 20120601
Title: An overview of bilastine metabolism during preclinical investigations.
Journal: Drug and chemical toxicology 20120601
Title: Whole-cell configuration of the patch-clamp technique in the hERG channel assay to predict the ability of a compound to prolong QT interval.
Journal: Current protocols in pharmacology 20120601
Title: Enhancement of clara cell 10-kD protein (CC10) production from nasal epithelial cells by fexofenadine hydrochloride.
Journal: Asian Pacific journal of allergy and immunology 20120601
Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Journal: Journal of medicinal chemistry 20120524
Title: The electro-mechanical window in anaesthetized guinea pigs: a new marker in screening for Torsade de Pointes risk.
Journal: British journal of pharmacology 20120501
Title: Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects.
Journal: European journal of clinical pharmacology 20120501
Title: Effects of single therapeutic doses of promethazine, fexofenadine and olopatadine on psychomotor function and histamine-induced wheal- and flare-responses: a randomized double-blind, placebo-controlled study in healthy volunteers.
Journal: Archives of dermatological research 20120501
Title: Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120501
Title: Involvement of leukotriene B4 in itching in a mouse model of ocular allergy.
Journal: Experimental eye research 20120501
Title: Characterization of A-935142, a hERG enhancer, in the presence and absence of standard hERG blockers.
Journal: Life sciences 20120420
Title: Preseasonal prophylactic treatment with antihistamines suppresses IL-5 but not IL-33 mRNA expression in the nasal mucosa of patients with seasonal allergic rhinitis caused by Japanese cedar pollen.
Journal: Acta oto-laryngologica 20120401
Title: Different effects of the selective serotonin reuptake inhibitors fluvoxamine, paroxetine, and sertraline on the pharmacokinetics of fexofenadine in healthy volunteers.
Journal: Journal of clinical psychopharmacology 20120401
Title: Structure determination of fexofenadine-α-cyclodextrin complex by quantitative 2D ROESY analysis and molecular mechanics studies.
Journal: Magnetic resonance in chemistry : MRC 20120401
Title: In vitro-in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate.
Journal: European journal of drug metabolism and pharmacokinetics 20120301
Title: Carbamazepine differentially affects the pharmacokinetics of fexofenadine enantiomers.
Journal: British journal of clinical pharmacology 20120301
Title: A randomized control trail of stepwise treatment with fluticasone propionate nasal spray and fexofenadine hydrochloride tablet for seasonal allergic rhinitis.
Journal: Allergology international : official journal of the Japanese Society of Allergology 20120301
Title: Pharmacophore modeling for hERG channel facilitation.
Journal: Biochemical and biophysical research communications 20120203
Title: Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells.
Journal: Pflugers Archiv : European journal of physiology 20120201
Title: The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms.
Journal: The Journal of allergy and clinical immunology 20120201
Title: Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters?
Journal: Journal of clinical psychopharmacology 20120201
Title: Treatment of acquired perforating dermatosis with cantharidin.
Journal: Archives of dermatology 20120201
Title: Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress.
Journal: British journal of cancer 20120103
Title: Noninvasive evaluation of contractile behavior of cardiomyocyte monolayers based on motion vector analysis.
Journal: Tissue engineering. Part C, Methods 20120101
Title: Spectrofluorimetric determination of etodolac, moxepril HCl and fexofenadine HCl using europium sensitized fluorescence in bulk and pharmaceutical preparations.
Journal: Journal of fluorescence 20120101
Title: Effects of bepotastine and fexofenadine on histamine-induced flare, wheal and itch.
Journal: International archives of allergy and immunology 20120101
Title: The PI3-kinase/mTOR-targeting drug NVP-BEZ235 inhibits growth and IgE-dependent activation of human mast cells and basophils.
Journal: PloS one 20120101
Title: Toward a New Gold Standard for Early Safety: Automated Temperature-Controlled hERG Test on the PatchLiner.
Journal: Frontiers in pharmacology 20120101
Title: Incidence and risk of QTc interval prolongation among cancer patients treated with vandetanib: a systematic review and meta-analysis.
Journal: PloS one 20120101
Title: Histamine H1 antagonists and clinical characteristics of febrile seizures.
Journal: International journal of general medicine 20120101
Title: Adaptation and validation of the Urticaria Patient Daily Diary for adolescents.
Journal: Allergy and asthma proceedings 20120101
Title: Phenytoin in treatment of amiodarone-induced Torsades de pointes.
Journal: Indian journal of pharmacology 20120101
Title: Spectrophotometric Determination of Mycophenolate Mofetil as Its Charge-Transfer Complexes with Two π-Acceptors.
Journal: Journal of analytical methods in chemistry 20120101
Title: Mechanisms, risk factors, and management of acquired long QT syndrome: a comprehensive review.
Journal: TheScientificWorldJournal 20120101
Title: In vitro model for assessing arrhythmogenic properties of drugs based on high-resolution impedance measurements.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Development and validation of an automated high-throughput system for zebrafish in vivo screenings.
Journal: PloS one 20120101
Title: Drug discovery models and toxicity testing using embryonic and induced pluripotent stem-cell-derived cardiac and neuronal cells.
Journal: Stem cells international 20120101
Title: Triarylmethanes, a new class of cx50 inhibitors.
Journal: Frontiers in pharmacology 20120101
Title: The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats.
Journal: Biological & pharmaceutical bulletin 20120101
Title: Development of a highly sensitive methodology for quantitative determination of fexofenadine in a microdose study by multiple injection method using ultra-high performance liquid chromatography with tandem mass spectrometry.
Journal: Biological & pharmaceutical bulletin 20120101
Title: Comparison of nasal steroid with antihistamine in prophylactic treatment against pollinosis using an environmental challenge chamber.
Journal: Allergy and asthma proceedings 20120101
Title: Optimization using central composite design for antihistamines separation by nonaqueous capillary electrophoresis with electrochemical and electrochemiluminescence detections.
Journal: The Analyst 20111221
Title: Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example.
Journal: Rapid communications in mass spectrometry : RCM 20111215
Title: Introduction of a modular automated voltage-clamp platform and its correlation with manual human Ether-à-go-go related gene voltage-clamp data.
Journal: Assay and drug development technologies 20111201
Title: Terfenadine induces apoptosis and autophagy in melanoma cells through ROS-dependent and -independent mechanisms.
Journal: Apoptosis : an international journal on programmed cell death 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Fexofenadine-induced urticaria.
Journal: Annals of dermatology 20111201
Title: Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120
Title: Ameliorating effect of Yokukansan on the development of atopic dermatitis-like lesions and scratching behavior in socially isolated NC/Nga mice.
Journal: Archives of dermatological research 20111101
Title: Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.
Journal: Molecular pharmaceutics 20111003
Title: Evaluation of the genotoxicity and cytotoxicity of fexofenadine in cultured human peripheral blood lymphocytes.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20111001
Title: Simultaneous UFLC-ESI-MS/MS determination of piperine and piperlonguminine in rat plasma after oral administration of alkaloids from Piper longum L.: application to pharmacokinetic studies in rats.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111001
Title: Assessment of fexofenadine hydrochloride permeability and dissolution with an anionic surfactant using Caco-2 cells.
Journal: Die Pharmazie 20111001
Title: Validation of membrane vesicle-based breast cancer resistance protein and multidrug resistance protein 2 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110901
Title: Physiologically based pharmacokinetic modeling of intestinal first-pass metabolism of CYP3A substrates with high intestinal extraction.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110901
Title: Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110901
Title: Atypical antipsychotics and effects of muscarinic, serotonergic, dopaminergic and histaminergic receptor binding on insulin secretion in vivo: an animal model.
Journal: Schizophrenia research 20110901
Title: Quantification of the transporter substrate fexofenadine in cell lysates by liquid chromatography/tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20110830
Title: Histaminergic modulation of acetylcholine-induced γ oscillations in rat hippocampus.
Journal: Neuroreport 20110803
Title: Block of the hERG channel by bupivacaine: Electrophysiological and modeling insights towards stereochemical optimization.
Journal: European journal of medicinal chemistry 20110801
Title: The biological basis and clinical significance of hormonal imprinting, an epigenetic process.
Journal: Clinical epigenetics 20110801
Title: Buspirone, fexofenadine, and omeprazole: quantification of probe drugs and their metabolites in human plasma.
Journal: Journal of pharmaceutical and biomedical analysis 20110715
Title: Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Journal: Cardiovascular research 20110701
Title: Species differences in intestinal metabolic activities of cytochrome P450 isoforms between cynomolgus monkeys and humans.
Journal: Drug metabolism and pharmacokinetics 20110601
Title: In brief: fexofenadine (Allegra) and fruit juice.
Journal: The Medical letter on drugs and therapeutics 20110530
Title: Drug-induced QTC prolongation dangerously underestimates proarrhythmic potential: lessons from terfenadine.
Journal: Journal of cardiovascular pharmacology 20110501
Title: A new cytochrome P450 belonging to the 107L subfamily is responsible for the efficient hydroxylation of the drug terfenadine by Streptomyces platensis.
Journal: Archives of biochemistry and biophysics 20110401
Title: Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury.
Journal: Pain 20110401
Title: Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation.
Journal: European heart journal 20110401
Title: Potent farnesyltransferase inhibitors with 1,4-diazepane scaffolds as novel destabilizing microtubule agents in hormone-resistant prostate cancer.
Journal: Journal of medicinal chemistry 20110310
Title: Analysis of Relationship between Levofloxacin and Corrected QT Prolongation Using a Clinical Data Warehouse.
Journal: Healthcare informatics research 20110301
Title: Poloxamer/cyclodextrin/chitosan-based thermoreversible gel for intranasal delivery of fexofenadine hydrochloride.
Journal: Journal of pharmaceutical sciences 20110201
Title: Roles of affinity and lipophilicity in the slow kinetics of prostanoid receptor antagonists on isolated smooth muscle preparations.
Journal: British journal of pharmacology 20110201
Title: Present state and future perspectives of using pluripotent stem cells in toxicology research.
Journal: Archives of toxicology 20110201
Title: The effects of the SLCO2B1 c.1457C > T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans.
Journal: Pharmacogenetics and genomics 20110201
Title: Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro.
Journal: International archives of allergy and immunology 20110101
Title: Developmental changes in action potential prolongation by K+-channel blockers in chick myocardium.
Journal: Journal of pharmacological sciences 20110101
Title: The effect of histamine on ciliary beat frequency in the acute phase of allergic rhinitis.
Journal: American journal of otolaryngology 20110101
Title: Intranasal phototherapy is more effective than fexofenadine hydrochloride in the treatment of seasonal allergic rhinitis: results of a pilot study.
Journal: Photochemistry and photobiology 20110101
Title: Urticaria due to antihistamines.
Journal: Journal of investigational allergology & clinical immunology 20110101
Title: Validated stability-indicating spectrofluorimetric methods for the determination of ebastine in pharmaceutical preparations.
Journal: Chemistry Central journal 20110101
Title: A pseudo-randomised clinical trial of in situ gels of fluconazole for the treatment of oropharngeal candidiasis.
Journal: Trials 20110101
Title: Analysis of fexofenadine in pharmaceutical formulations using tris(1,10-phenanthroline)-ruthenium(II) peroxydisulphate chemiluminescence system in a multichip device.
Journal: Luminescence : the journal of biological and chemical luminescence 20110101
Title: Predicting drug side-effect profiles: a chemical fragment-based approach.
Journal: BMC bioinformatics 20110101
Title: hERGAPDbase: a database documenting hERG channel inhibitory potentials and APD-prolongation activities of chemical compounds.
Journal: Database : the journal of biological databases and curation 20110101
Title: A novel study design for antibiotic trials in acute exacerbations of COPD: MAESTRAL methodology.
Journal: International journal of chronic obstructive pulmonary disease 20110101
Title: Cardiac arrest provoked by itraconazole and amiodarone interaction: a case report.
Journal: Journal of medical case reports 20110101
Title: Development of a novel high-throughput analytical methodology, multiple injection method, for quantitative analysis in drug metabolism and pharmacokinetic studies using liquid chromatography with tandem mass spectrometry.
Journal: Biological & pharmaceutical bulletin 20110101
Title: Improvement of effect of water-in-oil microemulsion as an oral delivery system for fexofenadine: in vitro and in vivo studies.
Journal: International journal of nanomedicine 20110101
Title: IL-4 amplifies the pro-inflammatory effect of adenosine in human mast cells by changing expression levels of adenosine receptors.
Journal: PloS one 20110101
Title: Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials.
Journal: International archives of allergy and immunology 20110101
Title: Cough management: a practical approach.
Journal: Cough (London, England) 20110101
Title: Electrophysiological characterization of cardiomyocytes derived from human induced pluripotent stem cells.
Journal: Journal of pharmacological sciences 20110101
Title: Inhibition of HERG potassium channels by celecoxib and its mechanism.
Journal: PloS one 20110101
Title: Ebastine in chronic spontaneous urticaria in higher doses.
Journal: Indian journal of dermatology 20110101
Title: Substitute of Animals in Drug Research: An Approach Towards Fulfillment of 4R's.
Journal: Indian journal of pharmaceutical sciences 20110101
Title: Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets.
Journal: Chemistry Central journal 20110101
Title: In silico analysis of conformational changes induced by mutation of aromatic binding residues: consequences for drug binding in the hERG K+ channel.
Journal: PloS one 20110101
Title: Regional absorption of fexofenadine in rat intestine.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101223
Title: 20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: CYP3A4*16 and CYP3A4*18 alleles found in East Asians exhibit differential catalytic activities for seven CYP3A4 substrate drugs.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Cytochrome P450-derived eicosanoids: the neglected pathway in cancer.
Journal: Cancer metastasis reviews 20101201
Title: Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting.
Journal: Assay and drug development technologies 20101201
Title: Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells.
Journal: Molecular cancer therapeutics 20101201
Title: QTc interval prolongation by fexofenadine in healthy human volunteers and its correlation with plasma levels of fexofenadine: A demonstration of anticlockwise hysteresis.
Journal: Indian journal of pharmacology 20101201
Title: Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
Journal: Healthcare informatics research 20101201
Title: Influence of drug-transporter polymorphisms on the pharmacokinetics of fexofenadine enantiomers.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Pharmacokinetics of fexofenadine following LPS administration to rats.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20101101
Title: Fruit juice inhibition of uptake transport: a new type of food-drug interaction.
Journal: British journal of clinical pharmacology 20101101
Title: H1-receptor antagonists terfenadine and loratadine inhibit spontaneous growth of neoplastic mast cells.
Journal: Experimental hematology 20101001
Title: The relationship between the drug concentration profiles in plasma and the drug doses in the colon.
Journal: Chemical & pharmaceutical bulletin 20101001
Title: Induction of inflammatory cell accumulation by TM-N49 and promutoxin, two novel phospholipase A(2).
Journal: Toxicon : official journal of the International Society on Toxinology 20100915
Title: Discovering drug-drug interactions: a text-mining and reasoning approach based on properties of drug metabolism.
Journal: Bioinformatics (Oxford, England) 20100915
Title: Efficacy of leukotriene antagonists as concomitant therapy in allergic rhinitis.
Journal: The Laryngoscope 20100901
Title: A quantitative structure-activity relationship for the modulation effects of flavonoids on p-glycoprotein-mediated transport.
Journal: Chemical & pharmaceutical bulletin 20100901
Title: Oral bepotastine: in allergic disorders.
Journal: Drugs 20100820
Title: Preparation and evaluation of fexofenadine microemulsions for intranasal delivery.
Journal: International journal of pharmaceutics 20100816
Title: Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.
Journal: The Journal of clinical investigation 20100802
Title: LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones.
Journal: Bioorganic & medicinal chemistry letters 20100801
Title: Effect of metronidazole on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy male volunteers.
Journal: European journal of clinical pharmacology 20100701
Title: Multivariate data analysis of factors affecting the in vitro dissolution rate and the apparent solubility for a model basic drug substance in aqueous media.
Journal: Pharmaceutical research 20100701
Title: [Normal tissue tolerance to external beam radiation therapy: esophagus].
Journal: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20100701
Title: Histamine and histamine receptor antagonists in cancer biology.
Journal: Inflammation & allergy drug targets 20100701
Title: Effects of K openers on the QT prolongation induced by HERG-blocking drugs in guinea-pigs.
Journal: The Journal of pharmacy and pharmacology 20100701
Title: Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations.
Journal: Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20100628
Title: Melt-in-mouth pellets of fexofenadine hydrochloride using crospovidone as an extrusion-spheronisation aid.
Journal: AAPS PharmSciTech 20100601
Title: Pharmacokinetics of fexofenadine: evaluation of a microdose and assessment of absolute oral bioavailability.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100512
Title: The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge Chamber.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100501
Title: Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100416
Title: Induction of microvascular leakage and histamine release by promutoxin, an Arg49 phospholipase A2.
Journal: Toxicon : official journal of the International Society on Toxinology 20100401
Title: Altered cytosolic Ca2+ dynamics in cultured Guinea pig cardiomyocytes as an in vitro model to identify potential cardiotoxicants.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100401
Title: Interactions at human ether-à-go-go-related gene channels.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100401
Title: Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
Journal: Clinical pharmacokinetics 20100401
Title: Direct analysis of dried blood spots utilizing desorption electrospray ionization (DESI) mass spectrometry.
Journal: The Analyst 20100401
Title: The pathophysiology, diagnosis and treatment of allergic rhinitis.
Journal: Allergy, asthma & immunology research 20100401
Title: Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS.
Journal: Journal of clinical pharmacy and therapeutics 20100401
Title: Effect of piperine, a major component of black pepper, on the intestinal absorption of fexofenadine and its implication on food-drug interaction.
Journal: Journal of food science 20100401
Title: Measurement of fexofenadine concentration in micro-sample human plasma by a rapid and sensitive LC-MS/MS employing protein precipitation: application to a clinical pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20100301
Title: Teriparatide is safe and effectively increases bone biomarkers in institutionalized individuals with osteoporosis.
Journal: Journal of bone and mineral metabolism 20100301
Title: Histamine influence on apoptosis in trophoblast cell cultures.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301
Title: Toward a consensus model of the HERG potassium channel.
Journal: ChemMedChem 20100301
Title: Development of a novel system for estimating human intestinal absorption using Caco-2 cells in the absence of esterase activity.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100201
Title: Identification of novel substrates for human cytochrome P450 2J2.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100201
Title: Validation and application of a liquid chromatography-tandem mass spectrometric method for quantification of the drug transport probe fexofenadine in human plasma using 96-well filter plates.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201
Title: Evaluation and performance of desorption electrospray ionization using a triple quadrupole mass spectrometer for quantitation of pharmaceuticals in plasma.
Journal: Rapid communications in mass spectrometry : RCM 20100201
Title: Building a tiered approach to in vitro predictive toxicity screening: a focus on assays with in vivo relevance.
Journal: Combinatorial chemistry & high throughput screening 20100201
Title: Loratadine versus levocetirizine in chronic idiopathic urticaria: A comparative study of efficacy and safety.
Journal: Indian journal of pharmacology 20100201
Title: Dog left ventricular midmyocardial myocytes for assessment of drug-induced delayed repolarization: short-term variability and proarrhythmic potential.
Journal: British journal of pharmacology 20100101
Title: Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.
Journal: International archives of allergy and immunology 20100101
Title: Update on the evaluation of a new drug for effects on cardiac repolarization in humans: issues in early drug development.
Journal: British journal of pharmacology 20100101
Title: Clinical pharmacokinetics of fexofenadine enantiomers.
Journal: Expert opinion on drug metabolism & toxicology 20100101
Title: Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Journal: Bioorganic & medicinal chemistry letters 20100101
Title: [Administration of premedication with fexofenadine for paclitaxel-induced hypersensitive reactions in breast cancer patients complicated with closed-angle glaucoma].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20100101
Title: The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes.
Journal: Journal of pharmacological and toxicological methods 20100101
Title: Interferences of the autonomic nervous system with drug induced QT prolongation: a point to consider in non-clinical safety studies.
Journal: Journal of pharmacological and toxicological methods 20100101
Title: Uni- or bi-ventricular hypertrophy and susceptibility to drug-induced torsades de pointes.
Journal: Journal of pharmacological and toxicological methods 20100101
Title: Treatment of congestion in upper respiratory diseases.
Journal: International journal of general medicine 20100101
Title: Rhinitis in the geriatric population.
Journal: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20100101
Title: Simultaneous determination of gliquidone, fexofenadine, buclizine, and levocetirizine in dosage formulation and human serum by RP-HPLC.
Journal: Journal of chromatographic science 20100101
Title: Preparation and evaluation of transdermal plasters containing norfloxacin: a novel treatment for burn wound healing.
Journal: Eplasty 20100101
Title: Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma.
Journal: Respiratory research 20100101
Title: Azelastine hydrochloride, a dual-acting anti-inflammatory ophthalmic solution, for treatment of allergic conjunctivitis.
Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101
Title: Emerging treatments in the management of schizophrenia - focus on sertindole.
Journal: Drug design, development and therapy 20100101
Title: Evaluation of terfenadine and ketoconazole-induced QT prolongation in conscious telemetered guinea pigs.
Journal: Pharmacological reports : PR 20100101
Title: Inhibitory effects of the methanol extract of Ganoderma lucidum on mosquito allergy-induced itch-associated responses in mice.
Journal: Journal of pharmacological sciences 20100101
Title: Fosaprepitant and aprepitant: an update of the evidence for their place in the prevention of chemotherapy-induced nausea and vomiting.
Journal: Core evidence 20100101
Title: Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system.
Journal: Malaria journal 20100101
Title: Development, clinical utility, and place in therapy of posaconazole for prevention and treatment of invasive fungal infections.
Journal: Drug design, development and therapy 20100101
Title: Stereoselective block of hERG channel by bupivacaine scrutinized at molecular level.
Journal: Chimia 20100101
Title: Study of the Complexation Behaviour of Fexofenadine with β-Cyclodextrin.
Journal: Indian journal of pharmaceutical sciences 20100101
Title: Clinical utility and patient adherence with ebastine for allergic rhinitis.
Journal: Patient preference and adherence 20100101
Title: Management of tinea capitis in childhood.
Journal: Clinical, cosmetic and investigational dermatology 20100101
Title: Update on the management of chronic eczema: new approaches and emerging treatment options.
Journal: Clinical, cosmetic and investigational dermatology 20100101
Title: Clinical safety and tolerability issues in use of triazole derivatives in management of fungal infections.
Journal: Drug, healthcare and patient safety 20100101
Title: Natural product taking its own place!!!
Journal: Pharmacognosy research 20100101
Title: Stereoselective Inhibition of the hERG1 Potassium Channel.
Journal: Frontiers in pharmacology 20100101
Title: Long-term treatment of patients with HIV-1: the role of atazanavir.
Journal: HIV/AIDS (Auckland, N.Z.) 20100101
Title: N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a 'chemical knock-out equivalent' to assess the impact of efflux transporters on oral drug absorption in the rat.
Journal: Journal of pharmaceutical sciences 20091201
Title: Leukotriene B(4) mediates sphingosylphosphorylcholine-induced itch-associated responses in mouse skin.
Journal: The Journal of investigative dermatology 20091201
Title: Genetic deficiency of carnitine/organic cation transporter 2 (slc22a5) is associated with altered tissue distribution of its substrate pyrilamine in mice.
Journal: Biopharmaceutics & drug disposition 20091201
Title: Effects of the P-glycoprotein inducer carbamazepine on fexofenadine pharmacokinetics.
Journal: Therapeutic drug monitoring 20091201
Title: Inhibition of the human ether-a-go-go-related gene (HERG) K+ channels by Lindera erythrocarpa.
Journal: Journal of Korean medical science 20091201
Title: Assessment of the antiobstructive effect of fexofenadine on nasal allergy challenge in patients with seasonal allergic rhinitis.
Journal: Asian Pacific journal of allergy and immunology 20091201
Title: A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel.
Journal: Analytical biochemistry 20091101
Title: Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis--a randomized placebo-controlled study.
Journal: Pediatric pulmonology 20091101
Title: Efavirenz: a decade of clinical experience in the treatment of HIV.
Journal: The Journal of antimicrobial chemotherapy 20091101
Title: ESRD impairs nonrenal clearance of fexofenadine but not midazolam.
Journal: Journal of the American Society of Nephrology : JASN 20091001
Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Journal: Nature chemical biology 20091001
Title: Comparing the stimulant effects of the H1-antagonist fexofenadine with 2 psychostimulants, modafinil and methylphenidate.
Journal: Journal of clinical psychopharmacology 20091001
Title: Allergen-induced airway inflammation and its therapeutic intervention.
Journal: Allergy, asthma & immunology research 20091001
Title: Unintended consequences of reducing QT-alert overload in a computerized physician order entry system.
Journal: European journal of clinical pharmacology 20090901
Title: Structural determinants for histamine H(1) affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs.
Journal: Bioorganic & medicinal chemistry letters 20090901
Title: Effects of 4-Aminopyridine on Cloned hERG Channels Expressed in Mammalian Cells.
Journal: Archives of drug information 20090901
Title: Integration of preclinical and clinical data with pharmacokinetic modeling and simulation to evaluate fexofenadine as a probe for hepatobiliary transport function.
Journal: Pharmaceutical research 20090801
Title: Ureteral stones due to systemic mastocytosis: diagnostic and therapeutic characteristics.
Journal: Urological research 20090801
Title: Effect of St John's wort on the disposition of fexofenadine in the isolated perfused rat liver.
Journal: The Journal of pharmacy and pharmacology 20090801
Title: Iatrogenic QT Abnormalities and Fatal Arrhythmias: Mechanisms and Clinical Significance.
Journal: Current cardiology reviews 20090801
Title: Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
Journal: Journal of medicinal chemistry 20090723
Title: Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders.
Journal: Expert opinion on drug metabolism & toxicology 20090701
Title: Allergies in India: a study on medication compliance.
Journal: Journal of the Indian Medical Association 20090701
Title: Pharmacokinetic drug interaction between fexofenadine and fluvastatin mediated by organic anion-transporting polypeptides in rats.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628
Title: Ether-à-gogo-related gene (erg1) potassium channels shape the dark response of horizontal cells in the mammalian retina.
Journal: Pflugers Archiv : European journal of physiology 20090601
Title: Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers.
Journal: European journal of clinical pharmacology 20090601
Title: Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo.
Journal: The Journal of pharmacology and experimental therapeutics 20090601
Title: Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090601
Title: Ether-à-go-go-related gene K+ channels contribute to threshold excitability of mouse auditory brainstem neurons.
Journal: The Journal of physiology 20090601
Title: Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis.
Journal: Allergology international : official journal of the Japanese Society of Allergology 20090601
Title: Fexofenadine hydrochloride enhances the efficacy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 cases.
Journal: The Journal of dermatology 20090601
Title: Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090601
Title: Analogs of MK-499 are differentially affected by a mutation in the S6 domain of the hERG K+ channel.
Journal: Biochemical pharmacology 20090515
Title: Relationship between airborne pollen count and treatment outcome in Japanese cedar pollinosis patients.
Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20090501
Title: Managing toxicities and optimal dosing of targeted drugs in advanced kidney cancer.
Journal: Current oncology (Toronto, Ont.) 20090501
Title: A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis.
Journal: Clinical therapeutics 20090501
Title: Enantioselective disposition of fexofenadine with the P-glycoprotein inhibitor verapamil.
Journal: British journal of clinical pharmacology 20090501
Title: In vitro metabolism and inhibitory effects of pranlukast in human liver microsomes.
Journal: Biological & pharmaceutical bulletin 20090401
Title: Multiple H1-antihistamine-induced urticaria.
Journal: The Journal of dermatology 20090401
Title: Docking model of drug binding to the human ether-à-go-go potassium channel guided by tandem dimer mutant patch-clamp data: a synergic approach.
Journal: Journal of medicinal chemistry 20090326
Title: Safety of the novel atrial-selective K+-channel blocker AVE0118 in experimental heart failure.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20090301
Title: The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090301
Title: Fexofenadine brain exposure and the influence of blood-brain barrier P-glycoprotein after fexofenadine and terfenadine administration.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090301
Title: Psychoactive medication and traffic safety.
Journal: International journal of environmental research and public health 20090301
Title: Calculation of QT shift in non clinical safety pharmacology studies.
Journal: Journal of pharmacological and toxicological methods 20090101
Title: Solar urticaria successfully treated with intravenous immunoglobulins.
Journal: Dermatology (Basel, Switzerland) 20090101
Title: Noninvasive technique for measurement of heartbeat regularity in zebrafish (Danio rerio) embryos.
Journal: BMC biotechnology 20090101
Title: IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model.
Journal: International archives of allergy and immunology 20090101
Title: Influence of epinastine hydrochloride, an H1-receptor antagonist, on the function of mite allergen-pulsed murine bone marrow-derived dendritic cells in vitro and in vivo.
Journal: Mediators of inflammation 20090101
Title: Induction of mast cell accumulation, histamine release and skin edema by N49 phospholipase A2.
Journal: BMC immunology 20090101
Title: Validation of a voltage-sensitive dye (di-4-ANEPPS)-based method for assessing drug-induced delayed repolarisation in beagle dog left ventricular midmyocardial myocytes.
Journal: Journal of pharmacological and toxicological methods 20090101
Title: Role of atazanavir in the treatment of HIV infection.
Journal: Therapeutics and clinical risk management 20090101
Title: Fluticasone furoate nasal spray is more effective than fexofenadine for nighttime symptoms of seasonal allergy.
Journal: Allergy and asthma proceedings 20090101
Title: Evaluation of the efficacy and safety of olopatadine and fexofenadine compared with placebo in Japanese cedar pollinosis using an environmental exposure unit.
Journal: Journal of investigational allergology & clinical immunology 20090101
Title: Long-term effects of Panax ginseng on disposition of fexofenadine in rats in vivo.
Journal: The American journal of Chinese medicine 20090101
Title: Bioequivalence of fexofenadine tablet formulations assessed in healthy Iranian volunteers.
Journal: Arzneimittel-Forschung 20090101
Title: Engineering and validation of a novel lipid thin film for biomembrane modeling in lipophilicity determination of drugs and xenobiotics.
Journal: Journal of biological engineering 20090101
Title: Mechanistic modeling of hepatic transport from cells to whole body: application to napsagatran and fexofenadine.
Journal: Molecular pharmaceutics 20090101
Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.
Journal: PloS one 20090101
Title: Efficacy of repeated pretreatment with olopatadine hydrochloride on rhinitis induced by intranasal instillation of toluene-2,4-diisocyanate in rats.
Journal: Pharmacology 20090101
Title: Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.
Journal: Drugs 20090101
Title: Sudden elevation of liver enzymes in a 64-year-old patient: a case report.
Journal: Cases journal 20090101
Title: Treating rhinitis in the older population: special considerations.
Journal: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20090101
Title: Chronic urticaria and treatment options.
Journal: Indian journal of dermatology 20090101
Title: Effects of fexofenadine on inflammatory mediators in nasal lavage fluid in intermittent allergic rhinitis.
Journal: Journal of investigational allergology & clinical immunology 20090101
Title: Contact urticaria: present scenario.
Journal: Indian journal of dermatology 20090101
Title: Management of difficult urticaria.
Journal: Indian journal of dermatology 20090101
Title: Psoriasis vulgaris and digestive system disorders: is there a linkage?
Journal: Folia histochemica et cytobiologica 20090101
Title: Update on terbinafine with a focus on dermatophytoses.
Journal: Clinical, cosmetic and investigational dermatology 20090101
Title: Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines.
Journal: Journal of asthma and allergy 20090101
Title: QTc prolongation assessment in anticancer drug development: clinical and methodological issues.
Journal: Ecancermedicalscience 20090101
Title: Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201
Title: Design, data analysis, and simulation of in vitro drug transport kinetic experiments using a mechanistic in vitro model.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201
Title: An ion channel library for drug discovery and safety screening on automated platforms.
Journal: Assay and drug development technologies 20081201
Title: Drug binding to the inactivated state is necessary but not sufficient for high-affinity binding to human ether-à-go-go-related gene channels.
Journal: Molecular pharmacology 20081101
Title: Narrowband ultraviolet B phototherapy is beneficial in antihistamine-resistant symptomatic dermographism: a pilot study.
Journal: Journal of the American Academy of Dermatology 20081101
Title: Potential benefit from an H1-receptor antagonist on postexercise syncope in the heat.
Journal: Medicine and science in sports and exercise 20081101
Title: Cyamemazine metabolites: effects on human cardiac ion channels in-vitro and on the QTc interval in guinea pigs.
Journal: The Journal of pharmacy and pharmacology 20081101
Title: Activation of proteinase-activated receptors induces itch-associated response through histamine-dependent and -independent pathways in mice.
Journal: Journal of pharmacological sciences 20081101
Title: Molecular determinants of hERG channel block by terfenadine and cisapride.
Journal: Journal of pharmacological sciences 20081101
Title: Validation of the use of nonnaive surgically catheterized rats for pharmacokinetics studies.
Journal: Journal of the American Association for Laboratory Animal Science : JAALAS 20081101
Title: Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Journal: Journal of medicinal chemistry 20081009
Title: Effectiveness of twice daily azelastine nasal spray in patients with seasonal allergic rhinitis.
Journal: Therapeutics and clinical risk management 20081001
Title: Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities.
Journal: Clinical pharmacology and therapeutics 20081001
Title: Autonomic nervous system and cardiovascular system.
Journal: Indian journal of pharmacology 20081001
Title: Relative contribution of absorptive and secretory transporters to the intestinal absorption of fexofenadine in rats.
Journal: International journal of pharmaceutics 20080901
Title: Torsades de pointes liability inter-model comparisons: the experience of the QT PRODACT initiative.
Journal: Pharmacology & therapeutics 20080801
Title: Small mouse cholangiocytes proliferate in response to H1 histamine receptor stimulation by activation of the IP3/CaMK I/CREB pathway.
Journal: American journal of physiology. Cell physiology 20080801
Title: Probenecid, but not cystic fibrosis, alters the total and renal clearance of fexofenadine.
Journal: Journal of clinical pharmacology 20080801
Title: Literature-based evaluation of four 'hard endpoint' models for assessing drug-induced torsades de pointes liability.
Journal: British journal of pharmacology 20080801
Title: Fexofenadine effects on cognitive performance in aviators at ground level and simulated altitude.
Journal: Aviation, space, and environmental medicine 20080801
Title: Assessing QT prolongation in conscious dogs: validation of a beat-to-beat method.
Journal: Pharmacology & therapeutics 20080801
Title: The effects of topical (gel) astemizole and terfenadine on wound healing.
Journal: Indian journal of pharmacology 20080801
Title: A statistical methodology for drug-drug interaction surveillance.
Journal: Statistics in medicine 20080720
Title: A simple and rapid high performance liquid chromatographic method with fluorescence detection for the estimation of fexofenadine in rat plasma--application to preclinical pharmacokinetics.
Journal: Talanta 20080715
Title: Evaluation of the antihistamine effects of olopatadine, cetirizine and fexofenadine during a 24 h period: a double-blind, randomized, crossover, placebo-controlled comparison in skin responses induced by histamine iontophoresis.
Journal: Archives of dermatological research 20080701
Title: The effects of fexofenadine at steady-state on sleep architecture: a study using polysomnography in healthy Korean volunteers.
Journal: Expert opinion on pharmacotherapy 20080701
Title: Receptor-independent, vacuolar ATPase-mediated cellular uptake of histamine receptor-1 ligands: possible origin of pharmacological distortions and side effects.
Journal: Toxicology and applied pharmacology 20080615
Title: Spectrophotometric determination of terfenadine in pharmaceutical preparations by charge-transfer reactions.
Journal: Talanta 20080615
Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Journal: Journal of medicinal chemistry 20080612
Title: Current industrial practices in assessing CYP450 enzyme induction: preclinical and clinical.
Journal: The AAPS journal 20080601
Title: Enzyme systems of detoxication - overview of recent approaches.
Journal: Interdisciplinary toxicology 20080601
Title: Identification of terfenadine as an inhibitor of human CD81-receptor HCV-E2 interaction: synthesis and structure optimization.
Journal: Molecules (Basel, Switzerland) 20080507
Title: Probing ligand binding modes of human cytochrome P450 2J2 by homology modeling, molecular dynamics simulation, and flexible molecular docking.
Journal: Proteins 20080501
Title: Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.
Journal: Molecular pharmacology 20080501
Title: Practical recommendations on the use of lenalidomide in the management of myelodysplastic syndromes.
Journal: Annals of hematology 20080501
Title: Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080501
Title: The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers.
Journal: British journal of clinical pharmacology 20080501
Title: Modest effect of impaired P-glycoprotein on the plasma concentrations of fexofenadine, quinidine, and loperamide following oral administration in collies.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080501
Title: Assessing QT prolongation in conscious dogs: validation of a beat-to-beat method.
Journal: Pharmacology & therapeutics 20080501
Title: Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080501
Title: Investigation of the inhibitory effects of various drugs on the hepatic uptake of fexofenadine in humans.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080401
Title: Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
Journal: Methods and findings in experimental and clinical pharmacology 20080401
Title: Prevention of chemotherapy-induced nausea and vomiting: focus on fosaprepitant.
Journal: Therapeutics and clinical risk management 20080401
Title: Terfenadine-induced apoptosis in human melanoma cells is mediated through Ca2+ homeostasis modulation and tyrosine kinase activity, independently of H1 histamine receptors.
Journal: Carcinogenesis 20080301
Title: Informatic tools and approaches in postmarketing pharmacovigilance used by FDA.
Journal: The AAPS journal 20080301
Title: Domoic acid toxicologic pathology: a review.
Journal: Marine drugs 20080301
Title: Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants.
Journal: Circulation 20080219
Title: Fexofenadine in pediatrics: oral tablet and suspension formulations.
Journal: Expert opinion on pharmacotherapy 20080201
Title: Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects.
Journal: Current medical research and opinion 20080201
Title: A review of solifenacin in the treatment of urinary incontinence.
Journal: Therapeutics and clinical risk management 20080201
Title: Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Journal: Journal of medicinal chemistry 20080124
Title: Isolation and structure elucidation of photodegradation products of fexofenadine.
Journal: Journal of pharmaceutical and biomedical analysis 20080122
Title: Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms.
Journal: Journal of pharmaceutical and biomedical analysis 20080122
Title: Aging-related changes of QT and RR intervals in conscious guinea pigs.
Journal: Journal of pharmacological and toxicological methods 20080101
Title: Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080101
Title: Fexofenadine downmodulates antigen-presenting ability of murine epidermal Langerhans cells.
Journal: Journal of dermatological science 20080101
Title: Atopic cough-like cough hypersensitivity caused by active sensitization with protein fraction of Aspergillus restrictus strain A-17.
Journal: Pulmonary pharmacology & therapeutics 20080101
Title: Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.
Journal: Clinical pharmacokinetics 20080101
Title: In vitro inhibition of rat basophilic leukaemia mast cell (RBL-2H3) degranulation by novel indane compounds.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080101
Title: Non-interventional study comparing treatment satisfaction in patients treated with antihistamines.
Journal: Clinical drug investigation 20080101
Title: An overview of harms associated with beta-lactam antimicrobials: where do the carbapenems fit in?
Journal: Critical care (London, England) 20080101
Title: Pharmacokinetics, safety and tolerability of an oral suspension of fexofenadine for children with allergic rhinitis.
Journal: Allergy and asthma proceedings 20080101
Title: Comparative efficacy of levocetirizine, desloratidine and fexofenadine by histamine wheal suppression test.
Journal: Indian journal of dermatology, venereology and leprology 20080101
Title: Loratadine provides early symptom control in seasonal allergic rhinitis.
Journal: Allergy and asthma proceedings 20080101
Title: Role of cytochrome P450 in drug interactions.
Journal: Nutrition & metabolism 20080101
Title: Extended driving impairs nocturnal driving performances.
Journal: PloS one 20080101
Title: A novel approach to the prediction of drug-drug interactions in humans based on the serum incubation method.
Journal: Drug metabolism and pharmacokinetics 20080101
Title: Visualization of first-pass drug metabolism of terfenadine by MALDI-imaging mass spectrometry.
Journal: Drug metabolism letters 20080101
Title: Psychological factors in asthma.
Journal: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101
Title: Alternative and improved method for the simultaneous determination of fexofenadine and pseudoephedrine in their combined tablet formulation.
Journal: Journal of pharmaceutical and biomedical analysis 20071221
Title: Antihistamine and sodium cromoglycate medication for food cold water exercise-induced anaphylaxis.
Journal: Allergy 20071201
Title: [Linear dermatitis due to shiitake mushrooms].
Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20071201
Title: Two cases of alopecia areata responsive to fexofenadine.
Journal: The Journal of dermatology 20071201
Title: Safety and tolerability of fexofenadine hydrochloride, 15 and 30 mg, twice daily in children aged 6 months to 2 years with allergic rhinitis.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20071201
Title: Laser ablation electrospray ionization for atmospheric pressure, in vivo, and imaging mass spectrometry.
Journal: Analytical chemistry 20071101
Title: Fexofenadine/cyclodextrin inclusion complexation: phase solubility, thermodynamic, physicochemical, and computational analysis.
Journal: Drug development and industrial pharmacy 20071101
Title: Microdose clinical trial: quantitative determination of fexofenadine in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015
Title: Suppressive activity of fexofenadine hydrochloride on nitric oxide production in-vitro and in-vivo.
Journal: The Journal of pharmacy and pharmacology 20071001
Title: Safety and tolerability of fexofenadine for the treatment of allergic rhinitis in children 2 to 5 years old.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20071001
Title: Measurements of blood pressure and electrocardiogram in conscious freely moving guineapigs: a model for screening QT interval prolongation effects.
Journal: Laboratory animals 20071001
Title: Detection and reporting of drug-induced proarrhythmias: room for improvement.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20070901
Title: Possible involvement of 5-lipoxygenase metabolite in itch-associated response of mosquito allergy in mice.
Journal: Journal of pharmacological sciences 20070901
Title: QT prolongation and safety in the Indian population.
Journal: Current drug safety 20070901
Title: Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.
Journal: Archives of biochemistry and biophysics 20070815
Title: Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin.
Journal: Biochemical pharmacology 20070801
Title: State dependent dissociation of HERG channel inhibitors.
Journal: British journal of pharmacology 20070801
Title: Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?
Journal: Clinical pharmacology and therapeutics 20070801
Title: Formaldehyde-induced urticarial vasculitis.
Journal: The Australasian journal of dermatology 20070801
Title: Phase II testing of sunitinib: the National Cancer Institute of Canada Clinical Trials Group IND Program Trials IND.182-185.
Journal: Current oncology (Toronto, Ont.) 20070801
Title: Role of posaconazole in the management of oropharyngeal and esophageal candidiasis.
Journal: Therapeutics and clinical risk management 20070801
Title: Combination therapy using fexofenadine, disodium cromoglycate, and a hypoallergenic amino acid-based formula induced remission in a patient with steroid-dependent, chronically active ulcerative colitis.
Journal: International journal of colorectal disease 20070701
Title: Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellular carcinoma cells.
Journal: Experimental & molecular medicine 20070630
Title: Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice.
Journal: European journal of pharmacology 20070601
Title: Toxicological significance of mechanism-based inactivation of cytochrome p450 enzymes by drugs.
Journal: Critical reviews in toxicology 20070601
Title: Bioequivalence of two fexofenadine formulations in healthy human volunteers after single oral administration.
Journal: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20070601
Title: A brief review of moxifloxacin in the treatment of elderly patients with community-acquired pneumonia (CAP).
Journal: Clinical interventions in aging 20070601
Title: Montelukast in the management of allergic rhinitis.
Journal: Therapeutics and clinical risk management 20070601
Title: Hydroxypropyl beta-cyclodextrins: a misleading vehicle for the in vitro hERG current assay.
Journal: Journal of cardiovascular pharmacology 20070501
Title: Characterization of antihistamine-human serum protein interactions by capillary electrophoresis.
Journal: Journal of chromatography. A 20070420
Title: Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.
Journal: Clinical pharmacology and therapeutics 20070401
Title: Effect of oral ketoconazole on intestinal first-pass effect of midazolam and fexofenadine in cynomolgus monkeys.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301
Title: Intestinal drug transporter expression and the impact of grapefruit juice in humans.
Journal: Clinical pharmacology and therapeutics 20070301
Title: Pharmacokinetics of fexofenadine enantiomers in healthy subjects.
Journal: Chirality 20070301
Title: Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.
Journal: Biological & pharmaceutical bulletin 20070301
Title: Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer.
Journal: International journal of pharmaceutics 20070207
Title: Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070201
Title: Assessment of the first and second generation antihistamines brain penetration and role of P-glycoprotein.
Journal: Pharmaceutical research 20070201
Title: Quantification of fexofenadine in human plasma by liquid chromatography coupled to electrospray tandem mass spectrometry using mosapride as internal standard.
Journal: Biomedical chromatography : BMC 20070201
Title: Simple and reliable HPLC analysis of fexofenadine hydrochloride in tablets and its application to dissolution studies.
Journal: Die Pharmazie 20070201
Title: The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria.
Journal: Cutis 20070201
Title: Determination of fexofenadine enantiomers in human plasma with high-performance liquid chromatography.
Journal: Journal of pharmaceutical and biomedical analysis 20070117
Title: A novel approach to data processing of the QT interval response in the conscious telemetered beagle dog.
Journal: Journal of pharmacological and toxicological methods 20070101
Title: Teriparatide in postmenopausal women with osteoporosis and mild or moderate renal impairment.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20070101
Title: Differences in arrhythmogenicity between the canine right ventricular outflow tract and anteroinferior right ventricle in a model of Brugada syndrome.
Journal: Heart rhythm 20070101
Title: QT prolongation in guinea pigs for preliminary screening of torsadogenicity of drugs and drug-candidates. II.
Journal: Journal of applied toxicology : JAT 20070101
Title: Inhibition of cytokine-induced expression of T-cell cytokines by antihistamines.
Journal: Journal of investigational allergology & clinical immunology 20070101
Title: Synthesis and assessment of first-generation polyamidoamine dendrimer prodrugs to enhance the cellular permeability of P-gp substrates.
Journal: Bioconjugate chemistry 20070101
Title: Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare.
Journal: Allergy and asthma proceedings 20070101
Title: Direct injection liquid chromatographic technique for simultaneous determination of two antihistaminic drugs and their main metabolites in serum.
Journal: Journal of AOAC International 20070101
Title: WJES and case reports/case series.
Journal: World journal of emergency surgery : WJES 20070101
Title: Evaluation of the guinea pig monophasic action potential (MAP) assay in predicting drug-induced delay of ventricular repolarisation using 12 clinically documented drugs.
Journal: Journal of pharmacological and toxicological methods 20070101
Title: Comparison of guinea-pig ventricular myocytes and dog Purkinje fibres for in vitro assessment of drug-induced delayed repolarization.
Journal: Journal of pharmacological and toxicological methods 20070101
Title: Comparison of the QT interval response during sinus and paced rhythm in conscious and anesthetized beagle dogs.
Journal: Journal of pharmacological and toxicological methods 20070101
Title: Some pharmacokinetic aspects of the lipophilic terfenadine and zwitterionic fexofenadine in humans.
Journal: Drugs in R&D 20070101
Title: Medicinal importance of grapefruit juice and its interaction with various drugs.
Journal: Nutrition journal 20070101
Title: Improved functional expression of recombinant human ether-a-go-go (hERG) K+ channels by cultivation at reduced temperature.
Journal: BMC biotechnology 20070101
Title: Food-dependent exercise-induced anaphylaxis: a case related to chickpea ingestion and review.
Journal: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20070101
Title: Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting.
Journal: Core evidence 20070101
Title: The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes.
Journal: European journal of pharmacology 20061228
Title: Electrophysiological effects of brompheniramine on cardiac ion channels and action potential.
Journal: Pharmacological research 20061201
Title: Comparison of four rate-correction algorithms for the ventricular repolarization period in assessing net effects of IKr blockers in dogs.
Journal: Journal of pharmacological sciences 20061201
Title: Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs.
Journal: European annals of allergy and clinical immunology 20061201
Title: The CML-related oncoprotein BCR/ABL induces expression of histidine decarboxylase (HDC) and the synthesis of histamine in leukemic cells.
Journal: Blood 20061115
Title: Lack of dose-dependent effects of itraconazole on the pharmacokinetic interaction with fexofenadine.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20061101
Title: Inhibitory effect of carboxylic acid group on hERG binding.
Journal: Bioorganic & medicinal chemistry letters 20061101
Title: Treatment of allergic rhinitis can improve blood pressure control.
Journal: Journal of human hypertension 20061101
Title: Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels.
Journal: Clinical and experimental pharmacology & physiology 20061101
Title: New antihistamines: a critical view.
Journal: Jornal de pediatria 20061101
Title: Ultrarush venom desensitization after systemic reactions during conventional venom immunotherapy.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20061101
Title: [Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101
Title: [The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101
Title: Involvement of ionotropic purinergic receptors in the histamine-induced enhancement of the cough reflex sensitivity in guinea pigs.
Journal: European journal of pharmacology 20061010
Title: QT interval prolongation and beyond.
Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20061001
Title: Onset of action of fexofenadine hydrochloride 60 mg/pseudoephedrine hydrochloride 120 mg in subjects aged 12 years with moderate to severe seasonal allergic rhinitis: a pooled analysis of two single-dose, randomized, double-blind, placebo-controlled allergen exposure unit studies.
Journal: Clinical therapeutics 20061001
Title: H1 histamine receptor antagonists induce genotoxic and caspase-2-dependent apoptosis in human melanoma cells.
Journal: Carcinogenesis 20060901
Title: Effects of single and multiple doses of itraconazole on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.
Journal: British journal of clinical pharmacology 20060901
Title: Altered oral bioavailability and pharmacokinetics of P-glycoprotein substrates by coadministration of biochanin A.
Journal: Journal of pharmaceutical sciences 20060901
Title: Long QT 1 mutation KCNQ1A344V increases local anesthetic sensitivity of the slowly activating delayed rectifier potassium current.
Journal: Anesthesiology 20060901
Title: Hepatobiliary disposition of a drug/metabolite pair: Comprehensive pharmacokinetic modeling in sandwich-cultured rat hepatocytes.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine.
Journal: British journal of clinical pharmacology 20060801
Title: Alteration of fexofenadine disposition in the rat isolated perfused liver following injection of bacterial lipopolysaccharide.
Journal: Clinical and experimental pharmacology & physiology 20060801
Title: Transporter-mediated intestinal absorption of fexofenadine in rats.
Journal: Drug metabolism and pharmacokinetics 20060801
Title: A combined neurophysiological and behavioural study into the stimulating effects of fexofenadine on performance.
Journal: Journal of psychopharmacology (Oxford, England) 20060701
Title: In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation.
Journal: American journal of physiology. Heart and circulatory physiology 20060701
Title: First-pass effects of verapamil on the intestinal absorption and liver disposition of fexofenadine in the porcine model.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701
Title: Stimulating effects of the antihistamine fexofenadine: testing the dopamine transporter hypothesis.
Journal: Psychopharmacology 20060701
Title: Time-dependent interaction between lopinavir/ritonavir and fexofenadine.
Journal: Journal of clinical pharmacology 20060701
Title: Allergy medication in Japanese volunteers: treatment effect of single doses on nocturnal sleep architecture and next day residual effects.
Journal: Current medical research and opinion 20060701
Title: Application of a mathematical topological pattern of antihistaminic activity for the selection of new drug candidates and pharmacology assays.
Journal: Journal of medicinal chemistry 20060615
Title: Differences of promethazine and terfenadine on ion channels in guinea pig ventricular myocytes.
Journal: Chinese medical journal 20060605
Title: Efficacy and central nervous system impairment of newer-generation prescription antihistamines in seasonal allergic rhinitis.
Journal: Southern medical journal 20060601
Title: Voriconazole in the management of nosocomial invasive fungal infections.
Journal: Therapeutics and clinical risk management 20060601
Title: Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model: high-resolution optical mapping study.
Journal: Journal of the American College of Cardiology 20060516
Title: Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
Journal: Bioorganic & medicinal chemistry letters 20060515
Title: New insights about HERG blockade obtained from protein modeling, potential energy mapping, and docking studies.
Journal: Bioorganic & medicinal chemistry 20060501
Title: Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060501
Title: Effect of P-glycoprotein on intestinal absorption and brain penetration of antiallergic agent bepotastine besilate.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Once-daily immediate-release fexofenadine and sustained-release pseudoephedrine combination: a new treatment option for allergic rhinitis.
Journal: Expert opinion on pharmacotherapy 20060501
Title: Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.
Journal: British journal of clinical pharmacology 20060501
Title: Pustular exacerbation of psoriasis due to fexofenadine.
Journal: Clinical and experimental dermatology 20060501
Title: Fexofenadine in horses: pharmacokinetics, pharmacodynamics and effect of ivermectin pretreatment.
Journal: Journal of veterinary pharmacology and therapeutics 20060401
Title: Effect of pretreatment with fexofenadine on the safety of immunotherapy in patients with allergic rhinitis.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060401
Title: Dimethyl lithospermate B, an extract of Danshen, suppresses arrhythmogenesis associated with the Brugada syndrome.
Journal: Circulation 20060321
Title: Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20060310
Title: Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs.
Journal: The Journal of pharmacology and experimental therapeutics 20060301
Title: Long-term bradycardia caused by atrioventricular block can remodel the canine heart to detect the histamine H1 blocker terfenadine-induced torsades de pointes arrhythmias.
Journal: British journal of pharmacology 20060301
Title: The effect of short- and long-term administration of verapamil on the disposition of cytochrome P450 3A and P-glycoprotein substrates.
Journal: Clinical pharmacology and therapeutics 20060301
Title: [Extension of QT interval as a consequence of risk factor accumulation--case study].
Journal: Vnitrni lekarstvi 20060301
Title: Effects of cyamemazine on hERG, INa, ICa, Ito, Isus and IK1 channel currents, and on the QTc interval in guinea pigs.
Journal: European journal of pharmacology 20060227
Title: Analysis of pharmaceutical preparations containing antihistamine drugs by micellar liquid chromatography.
Journal: Journal of pharmaceutical and biomedical analysis 20060213
Title: Efficacy of fexofenadine in the prophylactic control of cat allergen-induced allergic rhinitis.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060201
Title: Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers.
Journal: International journal of clinical pharmacology and therapeutics 20060201
Title: Fexofenadine, an H1-receptor antagonist, partially but rapidly inhibits the itch of contact dermatitis induced by diphenylcyclopropenone in patients with alopecia areata.
Journal: The Journal of dermatology 20060201
Title: Potent pruritogenic action of tryptase mediated by PAR-2 receptor and its involvement in anti-pruritic effect of nafamostat mesilate in mice.
Journal: European journal of pharmacology 20060113
Title: Differential effects of fexofenadine on arachidonic acid metabolism in cultured human monocytes.
Journal: Pharmacology 20060101
Title: Long QT syndrome: reduced repolarization reserve and the genetic link.
Journal: Journal of internal medicine 20060101
Title: A novel predictive pharmacokinetic/pharmacodynamic model of repolarization prolongation derived from the effects of terfenadine, cisapride and E-4031 in the conscious chronic av node--ablated, His bundle-paced dog.
Journal: Journal of pharmacological and toxicological methods 20060101
Title: [Long QT interval. Interaction of terfenadine and itraconazole].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20060101
Title: Drug-induced QT prolongation: an update.
Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20060101
Title: Enzymatic characteristics of CYP3A5 and CYP3A4: a comparison of in vitro kinetic and drug-drug interaction patterns.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20060101
Title: Dimethyl sulfoxide effects on hERG channels expressed in HEK293 cells.
Journal: Journal of pharmacological and toxicological methods 20060101
Title: In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist.
Journal: Drugs in R&D 20060101
Title: Dyspnea assessment and adverse events during sputum induction in COPD.
Journal: BMC pulmonary medicine 20060101
Title: Stimulating effects of H1-antagonists.
Journal: Current pharmaceutical design 20060101
Title: Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis.
Journal: Allergy and asthma proceedings 20060101
Title: Saliva secretion in patients with allergic rhinitis.
Journal: International archives of allergy and immunology 20060101
Title: Marketing of a new non-sedating antihistamine (fexofenadine) puts an additional burden on healthcare system resources in Israel.
Journal: The European journal of general practice 20060101
Title: Simultaneous quantification of fexofenadine and pseudoephedrine in human plasma by liquid chromatography/tandem mass spectrometry with electrospray ionization: method development, validation and application to a clinical study.
Journal: Rapid communications in mass spectrometry : RCM 20060101
Title: New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro.
Journal: Pharmacology 20060101
Title: The effect of fexofenadine on pruritus in a mouse model (HR-ADf) of atopic dermatitis.
Journal: The Journal of international medical research 20060101
Title: Selecting the optimal oral antihistamine for patients with allergic rhinitis.
Journal: Drugs 20060101
Title: [Safety of venom immunotherapy in patients pretreated with antihistamines--a retrospective study].
Journal: Pneumonologia i alergologia polska 20060101
Title: [Treatment of allergic rhinitis associated with hypothyroidism].
Journal: Vestnik otorinolaringologii 20060101
Title: The methanol disolvate and the dihydrate of fexofenadine, an antihistamine drug.
Journal: Acta crystallographica. Section C, Crystal structure communications 20051201
Title: Localized periorbital edema induced by Ibuprofen.
Journal: The Journal of dermatology 20051201
Title: The efficacy and safety of 30 mg fexofenadine HCl bid in pediatric patients with allergic rhinitis.
Journal: Asian Pacific journal of allergy and immunology 20051201
Title: Safety and tolerability of oral antifungal agents in the treatment of fungal nail disease: a proven reality.
Journal: Therapeutics and clinical risk management 20051201
Title: Drug-induced proarrhythmia and use of QTc-prolonging agents: clues for clinicians.
Journal: Heart rhythm 20051101
Title: hERG1 channels are overexpressed in glioblastoma multiforme and modulate VEGF secretion in glioblastoma cell lines.
Journal: British journal of cancer 20051003
Title: Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20051001
Title: Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis.
Journal: Pharmacology 20051001
Title: Reduction of repolarization reserve by halothane anaesthesia sensitizes the guinea-pig heart for drug-induced QT interval prolongation.
Journal: British journal of pharmacology 20051001
Title: Effects of fexofenadine and hydroxyzine on brake reaction time during car-driving with cellular phone use.
Journal: Human psychopharmacology 20051001
Title: Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20051001
Title: Brugada syndrome and ischemia-induced ST-segment elevation. Similarities and differences.
Journal: Journal of electrocardiology 20051001
Title: Treatment of ear pain in pilots in flight.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20051001
Title: The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis.
Journal: The Journal of dermatology 20051001
Title: Grape fruit juice-drug interactions.
Journal: Pakistan journal of pharmaceutical sciences 20051001
Title: [Wheat anaphylaxis enhanced by administration of acetylsalicylic acid or by exercise].
Journal: Arerugi = [Allergy] 20051001
Title: Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Journal: Bioorganic & medicinal chemistry letters 20050915
Title: L-selectin expression on neutrophils from allergic patients.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20050901
Title: Suppression of the histamine-induced wheal and flare response by fexofenadine HCl 60 mg twice daily, loratadine 10 mg once daily and placebo in healthy Japanese volunteers.
Journal: Current medical research and opinion 20050901
Title: Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050901
Title: Determination of fexofenadine in tablets by capillary electrophoresis in free solution and in solution with cyclodextrins as analyte carriers.
Journal: Drug development and industrial pharmacy 20050901
Title: Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050901
Title: Suppression of matrix metalloproteinase production in nasal fibroblasts by tranilast, an antiallergic agent, in vitro.
Journal: Mediators of inflammation 20050814
Title: Development and validation of dissolution tests for fexofenadine hydrochloride capsules and coated tablets.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050811
Title: Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines.
Journal: Journal of the American Academy of Nurse Practitioners 20050801
Title: Effect of itraconazole on the pharmacokinetics and pharmacodynamics of fexofenadine in relation to the MDR1 genetic polymorphism.
Journal: Clinical pharmacology and therapeutics 20050801
Title: The advantages of the Ussing chamber in drug absorption studies.
Journal: Journal of biomolecular screening 20050801
Title: Assessing the therapeutic benefits of antihistamines for the treatment of chronic idiopathic urticaria--a requirement for well-designed comparative clinical studies.
Journal: The Journal of dermatological treatment 20050801
Title: Practical application of guinea pig telemetry system for QT evaluation.
Journal: The Journal of toxicological sciences 20050801
Title: P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701
Title: Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administration.
Journal: British journal of clinical pharmacology 20050701
Title: Take allergy drug and sniff flowers safely?
Journal: Consumer reports 20050601
Title: Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050601
Title: Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Journal: Journal of medicinal chemistry 20050505
Title: Osteoporosis, teriparatide, and dosing of calcium and vitamin D.
Journal: The New England journal of medicine 20050505
Title: Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1).
Journal: British journal of clinical pharmacology 20050501
Title: QT interval prolongation and torsades de pointes due to a coadministration of metronidazole and amiodarone.
Journal: Pacing and clinical electrophysiology : PACE 20050501
Title: Single-dose and steady-state bioequivalence of fexofenadine and pseudoephedrine combination tablets compared with individual formulations in healthy adults.
Journal: Current medical research and opinion 20050501
Title: A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR.
Journal: Journal of medicinal chemistry 20050421
Title: Preferential downmodulation of certain chemokines by fexofenadine in human keratinocytes.
Journal: Journal of dermatological science 20050401
Title: The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050401
Title: Effect of trazodone on hERG channel current and QT-interval.
Journal: European journal of pharmacology 20050307
Title: H1 receptor-mediated vasodilatation contributes to postexercise hypotension.
Journal: The Journal of physiology 20050301
Title: CYP3A and P-glycoprotein activity induction with St. John's Wort in healthy volunteers from 6 ethnic populations.
Journal: Journal of clinical pharmacology 20050301
Title: Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides.
Journal: Clinical pharmacology and therapeutics 20050301
Title: Inhibition of tryptase release from human colon mast cells by histamine receptor antagonists.
Journal: Asian Pacific journal of allergy and immunology 20050301
Title: Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4.
Journal: Therapeutics and clinical risk management 20050301
Title: Effect of fruit juices on the oral bioavailability of fexofenadine in rats.
Journal: Journal of pharmaceutical sciences 20050201
Title: Fexofenadine improves the quality of life and work productivity in Japanese patients with seasonal allergic rhinitis during the peak cedar pollinosis season.
Journal: International archives of allergy and immunology 20050201
Title: Identification of human P450 isoforms involved in the metabolism of the antiallergic drug, oxatomide, and its kinetic parameters and inhibition constants.
Journal: Biological & pharmaceutical bulletin 20050201
Title: [Torsades de pointes caused by cetirizine overdose].
Journal: Archives des maladies du coeur et des vaisseaux 20050201
Title: Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination.
Journal: Journal of clinical pharmacology 20050101
Title: Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics.
Journal: Clinical pharmacology and therapeutics 20050101
Title: Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs.
Journal: Clinical pharmacokinetics 20050101
Title: Minimal important difference (MID) of the Dermatology Life Quality Index (DLQI): results from patients with chronic idiopathic urticaria.
Journal: Health and quality of life outcomes 20050101
Title: Use of a five-channel multiplexed electrospray quadrupole time-of-flight hybrid mass spectrometer for metabolite identification.
Journal: Rapid communications in mass spectrometry : RCM 20050101
Title: Estimation of potency of HERG channel blockers: impact of voltage protocol and temperature.
Journal: Journal of pharmacological and toxicological methods 20050101
Title: Cardiovascular parameters in anaesthetized guinea pigs: a safety pharmacology screening model.
Journal: Journal of pharmacological and toxicological methods 20050101
Title: Structural determinants for high-affinity block of hERG potassium channels.
Journal: Novartis Foundation symposium 20050101
Title: In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine.
Journal: BMC pharmacology 20050101
Title: Comparative effects of fexofenadine and montelukast on allergen-induced wheal and flare.
Journal: Allergy and asthma proceedings 20050101
Title: Capillary electrophoresis method for fexofenadine hydrochloride in capsules.
Journal: Journal of AOAC International 20050101
Title: Comparative efficacy of cetirizine and fexofenadine for seasonal allergic rhinitis, 5-12 hours postdose, in the environmental exposure unit.
Journal: Allergy and asthma proceedings 20050101
Title: The effect of fexofenadine on expression of intercellular adhesion molecule 1 and induction of apoptosis on peripheral eosinophils.
Journal: Allergy and asthma proceedings 20050101
Title: A Chronic Fatigue Syndrome - related proteome in human cerebrospinal fluid.
Journal: BMC neurology 20050101
Title: Greater risk of incident asthma cases in adults with allergic rhinitis and effect of allergen immunotherapy: a retrospective cohort study.
Journal: Respiratory research 20050101
Title: QT PRODACT: a multi-site study of in vitro action potential assays on 21 compounds in isolated guinea-pig papillary muscles.
Journal: Journal of pharmacological sciences 20050101
Title: QT PRODACT: in vivo QT assay in the conscious dog for assessing the potential for QT interval prolongation by human pharmaceuticals.
Journal: Journal of pharmacological sciences 20050101
Title: QT PRODACT: in vivo QT assay with a conscious monkey for assessment of the potential for drug-induced QT interval prolongation.
Journal: Journal of pharmacological sciences 20050101
Title: QT PRODACT: sensitivity and specificity of the canine telemetry assay for detecting drug-induced QT interval prolongation.
Journal: Journal of pharmacological sciences 20050101
Title: Simultaneous determination of ebastine and its three metabolites in plasma using liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225
Title: Evidence of significant contribution from CYP3A5 to hepatic drug metabolism.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20041201
Title: The utility of mixed-effects covariate analysis in rapid selection of doses in pediatric subjects: a case study with fexofenadine hydrochloride.
Journal: Biopharmaceutics & drug disposition 20041201
Title: Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20041201
Title: Suppressive activity of fexofenadine hydrochloride on metalloproteinase production from nasal fibroblasts in vitro.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20041201
Title: Microbial oxidation of terfenadine and ebastine into fexofenadine and carebastine.
Journal: Bioorganic & medicinal chemistry letters 20041101
Title: A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.
Journal: Clinical pharmacology and therapeutics 20041101
Title: Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
Journal: Journal of cardiovascular electrophysiology 20041101
Title: The crystallisation of a model hydrophobic drug (terfenadine) following exposure to humidity and organic vapours.
Journal: International journal of pharmaceutics 20041013
Title: Comparison of alamar blue and MTT assays for high through-put screening.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20041001
Title: Steady-state brain concentrations of antihistamines in rats: interplay of membrane permeability, P-glycoprotein efflux and plasma protein binding.
Journal: Pharmacology 20041001
Title: Automated tight seal electrophysiology for assessing the potential hERG liability of pharmaceutical compounds.
Journal: Assay and drug development technologies 20041001
Title: Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance.
Journal: Clinical and experimental dermatology 20040901
Title: Drug-drug interactions of Z-338, a novel gastroprokinetic agent, with terfenadine, comparison with cisapride, and involvement of UGT1A9 and 1A8 in the human metabolism of Z-338.
Journal: European journal of pharmacology 20040823
Title: Terfenadine induces thymocyte apoptosis via mitochondrial pathway.
Journal: European journal of pharmacology 20040802
Title: Venom immunotherapy: adverse reactions and treatment failure.
Journal: Current opinion in allergy and clinical immunology 20040801
Title: Central effects of fexofenadine and cetirizine: measurement of psychomotor performance, subjective sleepiness, and brain histamine H1-receptor occupancy using 11C-doxepin positron emission tomography.
Journal: Journal of clinical pharmacology 20040801
Title: Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.
Journal: Fundamental & clinical pharmacology 20040801
Title: Validation of the Dermatology Life Quality Index as an outcome measure for urticaria-related quality of life.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040801
Title: Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexofenadine.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040801
Title: A novel membrane sensor for histamine H1-receptor antagonist 'fexofenadine'.
Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040801
Title: Transport characteristics of fexofenadine in the Caco-2 cell model.
Journal: Pharmaceutical research 20040801
Title: Intradermal nociceptin elicits itch-associated responses through leukotriene B(4) in mice.
Journal: The Journal of investigative dermatology 20040701
Title: Validation of a [3H]astemizole binding assay in HEK293 cells expressing HERG K+ channels.
Journal: Journal of pharmacological sciences 20040701
Title: Role of sodium and calcium channel block in unmasking the Brugada syndrome.
Journal: Heart rhythm 20040701
Title: Determination of fexofenadine in human plasma using 96-well solid phase extraction and HPLC with tandem mass spectrometric detection.
Journal: Journal of pharmaceutical and biomedical analysis 20040629
Title: Liquid chromatographic determination of fexofenadine in human plasma with fluorescence detection.
Journal: Journal of pharmaceutical and biomedical analysis 20040629
Title: Drugs, hERG and sudden death.
Journal: Cell calcium 20040601
Title: Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis.
Journal: British journal of clinical pharmacology 20040601
Title: Lead identification for modulators of multidrug resistance based on in silico screening with a pharmacophoric feature model.
Journal: Archiv der Pharmazie 20040601
Title: Safety and efficacy of oral fexofenadine in children with seasonal allergic rhinitis--a pooled analysis of three studies.
Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20040601
Title: Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice.
Journal: British journal of pharmacology 20040501
Title: Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents.
Journal: Molecular pharmacology 20040501
Title: Fexofenadine does not affect omeprazole pharmacokinetics: both are putative P-glycoprotein substrates.
Journal: Basic & clinical pharmacology & toxicology 20040501
Title: Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels.
Journal: Acta pharmacologica Sinica 20040501
Title: Acid-base cosolvent method for determining aqueous permeability of amiodarone, itraconazole, tamoxifen, terfenadine and other very insoluble molecules.
Journal: Chemical & pharmaceutical bulletin 20040501
Title: Identification of human p450 isoforms involved in the metabolism of the antiallergic drug, oxatomide, and its inhibitory effect on enzyme activity.
Journal: Biological & pharmaceutical bulletin 20040501
Title: Comparative efficacy of wheal-and-flare suppression among various non-sedating antihistamines and the pharmacologic insights to their efficacy.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040501
Title: Integrating in vitro kinetic data from compounds exhibiting induction, reversible inhibition and mechanism-based inactivation: in vitro study design.
Journal: Current drug metabolism 20040401
Title: Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.
Journal: Chest 20040401
Title: A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040401
Title: Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040401
Title: Lack of association between fexofenadine and rhabdomyolysis.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040401
Title: Mizolastine and fexofenadine modulate cytokine pattern after nasal allergen challenge.
Journal: European annals of allergy and clinical immunology 20040401
Title: Physicochemical features of the HERG channel drug binding site.
Journal: The Journal of biological chemistry 20040312
Title: Suppressive activity of fexofenadine hydrochloride on thymus- and activation-regulated chemokine production from human peripheral blood leukocytes in response to antigenic stimulation in vitro.
Journal: International archives of allergy and immunology 20040301
Title: The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis.
Journal: International immunopharmacology 20040301
Title: Antihistamines and driving ability: evidence from on-the-road driving studies during normal traffic.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040301
Title: Polymorphism in generic drug product development.
Journal: Advanced drug delivery reviews 20040223
Title: Differential effect of HERG blocking agents on cardiac electrical alternans in the guinea pig.
Journal: European journal of pharmacology 20040220
Title: Application of data mining techniques in pharmacovigilance.
Journal: British journal of clinical pharmacology 20040201
Title: The effects of butterbur on the histamine and allergen cutaneous response.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040201
Title: Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine.
Journal: Managed care interface 20040201
Title: Lack of action potential-prolonging effect of terfenadine on rabbit myocardial tissue preparations.
Journal: Biological & pharmaceutical bulletin 20040101
Title: Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research.
Journal: Current medical research and opinion 20040101
Title: Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria.
Journal: The Journal of dermatological treatment 20040101
Title: Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20040101
Title: Randomized double-blind comparison of cetirizine and fexofenadine after pollen challenge in the Environmental Exposure Unit: duration of effect in subjects with seasonal allergic rhinitis.
Journal: Allergy and asthma proceedings 20040101
Title: Association between the number of coadministered P-glycoprotein inhibitors and serum digoxin levels in patients on therapeutic drug monitoring.
Journal: BMC medicine 20040101
Title: Quinolone safety and efficacy more important than potency.
Journal: Emerging infectious diseases 20040101
Title: Prolonged effect of an H1-receptor blocker antihistamine on the histamine content of white blood cells and mast cells.
Journal: Cell biochemistry and function 20040101
Title: Onset of action for the relief of allergic rhinitis symptoms with second-generation antihistamines.
Journal: Allergy and asthma proceedings 20040101
Title: QT prolongation in anaesthetized guinea-pigs: an experimental approach for preliminary screening of torsadogenicity of drugs and drug candidates.
Journal: Journal of applied toxicology : JAT 20040101
Title: Preventing serious drug interactions.
Journal: FDA consumer 20040101
Title: Suppressive activity of fexofenadine hydrochloride on the production of eosinophil chemoattractants from human nasal fibroblasts in vitro.
Journal: Arzneimittel-Forschung 20040101
Title: Development and validation of a liquid chromatographic method for fexofenadine hydrochloride in capsules.
Journal: Journal of AOAC International 20040101
Title: Improved precision and accuracy for high-performance liquid chromatography/Fourier transform ion cyclotron resonance mass spectrometric exact mass measurement of small molecules from the simultaneous and controlled introduction of internal calibrants via a second electrospray nebuliser.
Journal: Rapid communications in mass spectrometry : RCM 20040101
Title: Clinical study of the therapeutic efficacy and safety of emedastine difumarate versus terfenadine in the treatment of seasonal allergic rhinitis.
Journal: Arzneimittel-Forschung 20040101
Title: Fexofenadine HCl 60 mg/ pseudoephedrine HCl 120 mg has a 60-minute onset of action in the treatment of seasonal allergic rhinitis symptoms, as assessed in an allergen exposure unit.
Journal: Allergy and asthma proceedings 20040101
Title: [Serum sICAM-1 in patients suffering from allergic rhinitis treated with fexofenadine or fluticasone].
Journal: Pneumonologia i alergologia polska 20040101
Title: Actual therapeutic management of allergic and hyperreactive nasal disorders.
Journal: GMS current topics in otorhinolaryngology, head and neck surgery 20040101
Title: Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia.
Journal: Toxicology and applied pharmacology 20031215
Title: Atrioventricular nodal ablation and His-bundle pacing: an acute canine model for proarrhythmic risk assesment.
Journal: Journal of cardiovascular electrophysiology 20031201
Title: Comparative study of acute effects of single doses of fexofenadine, olopatadine, d-chlorpheniramine and placebo on psychomotor function in healthy volunteers.
Journal: Human psychopharmacology 20031201
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20031201
Title: Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia.
Journal: British journal of cancer 20031117
Title: Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine.
Journal: Clinical pharmacology and therapeutics 20031101
Title: A study comparing the inhibitory effects of single and repeated oral doses of ebastine and fexofenadine against histamine-induced skin reactivity.
Journal: International archives of allergy and immunology 20031101
Title: Effect of the second-generation antihistamine, fexofenadine, on cough reflex sensitivity and pulmonary function.
Journal: British journal of clinical pharmacology 20031101
Title: Mite-antigen induced immediate reactions in atopic dermatitis are inhibited by daily administration of fexofenadine.
Journal: The Journal of dermatology 20031101
Title: [Drug interactions. Mechanisms and clinical relevance].
Journal: Der Internist 20031101
Title: Efficacy and safety profile of fexofenadine HCl: a unique therapeutic option in H1-receptor antagonist treatment.
Journal: The Journal of allergy and clinical immunology 20031001
Title: Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion molecules.
Journal: The Journal of allergy and clinical immunology 20031001
Title: Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness.
Journal: The Journal of allergy and clinical immunology 20031001
Title: Prospects for antihistamines in the treatment of asthma.
Journal: The Journal of allergy and clinical immunology 20031001
Title: Is 3-mm less drowsiness important?
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001
Title: Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001
Title: H1-receptor blocker antihistamine, terfenadine durably influences the glucocorticoid receptor, and lymphocyte histamine content of weanling rats.
Journal: Pharmacological research 20030901
Title: Terfenadine antagonism against interleukin-4-modulated gene expression of T cell cytokines.
Journal: The Journal of investigative dermatology 20030901
Title: Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes.
Journal: European journal of biochemistry 20030901
Title: [Observation on effect of integrative Chinese and Western medicine in treating acute attack of bronchial asthma].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20030901
Title: Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Journal: Bioorganic & medicinal chemistry letters 20030818
Title: Sudden arrhythmia death syndrome: importance of the long QT syndrome.
Journal: American family physician 20030801
Title: Rapid assessment of P-glycoprotein inhibition and induction in vitro.
Journal: Pharmaceutical research 20030801
Title: Omalizumab, an anti-IgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030801
Title: The effects of fexofenadine on reaction time, decision-making, and driver behavior.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030801
Title: Randomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models.
Journal: Clinical therapeutics 20030801
Title: RNA synthesis-dependent potentiation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated toxicity by antihistamine terfenadine in cultured rat cerebellar neurons.
Journal: Neuroscience letters 20030717
Title: Inhibition of experimental allergic rhinitis by the n-butanol fraction from the anomalous fruits of Gleditsia sinensis.
Journal: Biological & pharmaceutical bulletin 20030701
Title: Herbal supplements and skin testing: the lack of effect of commonly used herbal supplements on histamine skin prick testing.
Journal: Allergy 20030601
Title: Supplementation of fexofenadine therapy with nedocromil sodium 2% ophthalmic solution to treat ocular symptoms of seasonal allergic conjunctivitis.
Journal: Clinical & experimental ophthalmology 20030601
Title: H1-antihistaminic activity of cetirizine and fexofenadine in allergic children.
Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20030601
Title: Pregnancy outcome after gestational exposure to loratadine or antihistamines: a prospective controlled cohort study.
Journal: The Journal of allergy and clinical immunology 20030601
Title: Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study.
Journal: The British journal of dermatology 20030601
Title: [Effects of clinically available drugs on the repolarization process of the heart assessed by the in vivo canine models].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20030601
Title: Relative potency of fexofenadine HCl 180 mg, loratadine 10 mg, and placebo using a skin test model of wheal-and-flare suppression.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030601
Title: In vitro inhibition of human small intestinal and liver microsomal astemizole O-demethylation: different contribution of CYP2J2 in the small intestine and liver.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030601
Title: [Clinical aspects of anti-inflammatory action of antihistamines].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030601
Title: Histamine H1 receptor antagonism by cetirizine in isolated guinea pig tissues: influence of receptor reserve and dissociation kinetics.
Journal: European journal of pharmacology 20030530
Title: Understanding the structure-activity relationship of the human ether-a-go-go-related gene cardiac K+ channel. A model for bad behavior.
Journal: Journal of medicinal chemistry 20030522
Title: Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches.
Journal: Bioorganic & medicinal chemistry letters 20030519
Title: Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain.
Journal: Molecular pharmacology 20030501
Title: Molecular mechanisms of G0/G1 cell-cycle arrest and apoptosis induced by terfenadine in human cancer cells.
Journal: Molecular carcinogenesis 20030501
Title: Effects of fexofenadine, diphenhydramine, and placebo on performance of the test of variables of attention (TOVA).
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030501
Title: Characteristics of the antihistamine effect of TAK-427, a novel imidazopyridazine derivative.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030501
Title: A single-center, randomized, double-blind, placebo-controlled, crossover investigation of the effects of fexofenadine hydrochloride 180 mg alone and with alcohol, with hydroxyzine hydrochloride 50 mg as a positive internal control, on aspects of cognitive and psychomotor function related to driving a car.
Journal: Clinical therapeutics 20030501
Title: Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
Journal: Journal of medicinal chemistry 20030424
Title: Famotidine does not induce long QT syndrome: experimental evidence from in vitro and in vivo test systems.
Journal: European journal of pharmacology 20030411
Title: Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis.
Journal: The Journal of allergy and clinical immunology 20030401
Title: Sedation and performance impairment of diphenhydramine and second-generation antihistamines: a meta-analysis.
Journal: The Journal of allergy and clinical immunology 20030401
Title: The effects of acute doses of fexofenadine, promethazine, and placebo on cognitive and psychomotor function in healthy Japanese volunteers.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030401
Title: Photomutagenic properties of terfenadine as revealed by a stepwise photostability, phototoxicity and photomutagenicity testing approach.
Journal: Photochemistry and photobiology 20030401
Title: [H1 histamine antagonists].
Journal: Revue medicale de Bruxelles 20030401
Title: Drugs that induce repolarization abnormalities cause bradycardia in zebrafish.
Journal: Circulation 20030318
Title: Decongestant effects of antihistamines: a class effect?
Journal: The Journal of allergy and clinical immunology 20030301
Title: Solar urticaria induced by infrared radiation.
Journal: Clinical and experimental dermatology 20030301
Title: Inhibitory effect of azelastine on allergic itch-associated response in mice sensitized with mosquito salivary glands extract.
Journal: Journal of pharmacological sciences 20030301
Title: Detection of proarrhythmia in the female rabbit heart: blinded validation.
Journal: Journal of cardiovascular electrophysiology 20030301
Title: Effect of fexofenadine hydrochloride on cedar pollinosis.
Journal: Auris, nasus, larynx 20030201
Title: Failure of cetirizine and fexofenadine to prevent motion sickness.
Journal: The Annals of pharmacotherapy 20030201
Title: Synthesis of eosinophil infiltration inhibitors with antihistaminic activity.
Journal: Chemical & pharmaceutical bulletin 20030201
Title: The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique.
Journal: British journal of clinical pharmacology 20030201
Title: Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
Journal: The Journal of allergy and clinical immunology 20030201
Title: The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel.
Journal: Aviation, space, and environmental medicine 20030201
Title: Functional and pharmacological properties of canine ERG potassium channels.
Journal: American journal of physiology. Heart and circulatory physiology 20030101
Title: Blinded test in isolated female rabbit heart reliably identifies action potential duration prolongation and proarrhythmic drugs: importance of triangulation, reverse use dependence, and instability.
Journal: Journal of cardiovascular pharmacology 20030101
Title: Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects.
Journal: Clinical pharmacology and therapeutics 20030101
Title: Internal standard signal suppression by co-eluting analyte in isotope dilution LC-ESI-MS.
Journal: The Analyst 20030101
Title: Lopinavir/ritonavir: a review of its use in the management of HIV infection.
Journal: Drugs 20030101
Title: Pharmacogenetics--the horizon.
Journal: Reviews in gastroenterological disorders 20030101
Title: [Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030101
Title: Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine.
Journal: BMC family practice 20030101
Title: Antihistamines.
Journal: Psychosomatics 20030101
Title: Issues related to monitoring the safety of over-the-counter (OTC) medicines.
Journal: Drug safety 20030101
Title: Cellular and ionic basis for the sex-related difference in the manifestation of the Brugada syndrome and progressive conduction disease phenotypes.
Journal: Journal of electrocardiology 20030101
Title: Substrate dependent inhibition profiles of fourteen drugs on CYP3A4 activity measured by a high throughput LCMS/MS method with four probe drugs, midazolam, testosterone, nifedipine and terfenadine.
Journal: Drug metabolism and pharmacokinetics 20030101
Title: Receptor-dependent regulation of the CYP3A4 gene.
Journal: Toxicology 20021227
Title: Roles of histamine in regulation of arousal and cognition: functional neuroimaging of histamine H1 receptors in human brain.
Journal: Life sciences 20021220
Title: Inhibition of allergic dermal inflammation by the novel imidazopyridazine derivative TAK-427 in a guinea pig experimental model of eczema.
Journal: The Journal of pharmacology and experimental therapeutics 20021201
Title: Inhibitory effects of oral prednisolone and fexofenadine on skin responses by prick tests with histamine and compound 48/80.
Journal: Journal of dermatological science 20021201
Title: Facial swelling and eosinophilia in a 44-year-old woman.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021201
Title: Effects of fexofenadine on the early response to nasal allergen challenge.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021201
Title: Effects of supratherapeutic doses of ebastine and terfenadine on the QT interval.
Journal: British journal of clinical pharmacology 20021201
Title: Effect of fexofenadine, a mast cell blocker, in infertile men with significantly increased testicular mast cells.
Journal: Asian journal of andrology 20021201
Title: Development of neuroleptic agents: pharmacogenetics and current safety issues of regulatory concern.
Journal: Dialogues in clinical neuroscience 20021201
Title: The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia.
Journal: British journal of pharmacology 20021101
Title: Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir.
Journal: Journal of clinical pharmacology 20021101
Title: Clinical pharmacology of H1-antihistamines in the skin.
Journal: The Journal of allergy and clinical immunology 20021101
Title: Comparative study of some additives for the improvement of terfenadine performance.
Journal: Die Pharmazie 20021101
Title: Ionic and cellular basis for the predominance of the Brugada syndrome phenotype in males.
Journal: Circulation 20021008
Title: Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20021001
Title: Aspirin-induced urticaria and angioedema, but not bronchoconstriction, associated with cysteinyl leukotriene overproduction in 2 patients with asthma.
Journal: The Journal of allergy and clinical immunology 20021001
Title: Data-mining analyses of pharmacovigilance signals in relation to relevant comparison drugs.
Journal: European journal of clinical pharmacology 20021001
Title: Review of fexofenadine in the treatment of chronic idiopathic urticaria.
Journal: International journal of dermatology 20021001
Title: The use of handheld computers in clinical trials.
Journal: Controlled clinical trials 20021001
Title: The relationship of clinical QT prolongation to outcome in the conscious dog using a beat-to-beat QT-RR interval assessment.
Journal: The Journal of pharmacology and experimental therapeutics 20020801
Title: The functional properties of the human ether-à-go-go-like (HELK2) K+ channel.
Journal: The European journal of neuroscience 20020801
Title: Molecular identification and characterisation of the human eag2 potassium channel.
Journal: FEBS letters 20020731
Title: Simultaneous determination of fexofenadine and its related compounds by HPLC.
Journal: Journal of pharmaceutical and biomedical analysis 20020720
Title: Chronic urticaria and angioedema.
Journal: The New England journal of medicine 20020718
Title: Role of lung inflammatory mediators as a cause of exercise-induced arterial hypoxemia in young athletes.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020701
Title: Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness.
Journal: The Journal of allergy and clinical immunology 20020701
Title: Onset of action, efficacy, and safety of fexofenadine 60 mg/pseudoephedrine 120 mg versus placebo in the Atlanta allergen exposure unit.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020701
Title: Comparison of the efficacy of combined fluticasone propionate and olopatadine versus combined fluticasone propionate and fexofenadine for the treatment of allergic rhinoconjunctivitis induced by conjunctival allergen challenge.
Journal: Clinical therapeutics 20020701
Title: In vivo anti-inflammatory effects of fexofenadine in chronic idiopathic urticaria.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20020701
Title: Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block.
Journal: Circulation 20020618
Title: Next generation antihistamines: therapeutic rationale, accomplishments and advances.
Journal: Expert opinion on investigational drugs 20020601
Title: Are herbal products dietary supplements or drugs? An important question for public safety.
Journal: Clinical pharmacology and therapeutics 20020601
Title: Effect of St John's wort on the pharmacokinetics of fexofenadine.
Journal: Clinical pharmacology and therapeutics 20020601
Title: The Rx-to-OTC switch of Claritin, Allegra, and Zyrtec: an unprecedented FDA response to petitioners and the protection of public health.
Journal: The American University law review 20020601
Title: Delineation of the protective action of zinc sulfate on ulcerative colitis in rats.
Journal: European journal of pharmacology 20020517
Title: Three-dimensional quantitative structure-activity relationship for inhibition of human ether-a-go-go-related gene potassium channel.
Journal: The Journal of pharmacology and experimental therapeutics 20020501
Title: MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.
Journal: British journal of clinical pharmacology 20020501
Title: Evaluation of cytokines in nasal secretions after nasal antigen challenge: lack of influence of antihistamines.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020501
Title: [Hay fever and asthma. Many of your patients have both].
Journal: MMW Fortschritte der Medizin 20020425
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: [Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients].
Journal: Praxis 20020410
Title: Intradermal cholinergic agonists induce itch-associated response via M3 muscarinic acetylcholine receptors in mice.
Journal: Japanese journal of pharmacology 20020301
Title: Cardiotoxicity of new antihistamines and cisapride.
Journal: Toxicology letters 20020227
Title: Antihistamines in late-phase clinical development for allergic disease.
Journal: Expert opinion on investigational drugs 20020201
Title: Proarrhythmic potential of halofantrine, terfenadine and clofilium in a modified in vivo model of torsade de pointes.
Journal: British journal of pharmacology 20020201
Title: A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020201
Title: Are antihistamines useful in managing asthma?
Journal: Current opinion in allergy and clinical immunology 20020201
Title: Determination of fexofenadine in human plasma and urine by liquid chromatography-mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020125
Title: Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020101
Title: Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.
Journal: Clinical pharmacology and therapeutics 20020101
Title: Effects of antihistamines on leukotriene and cytokine release from dispersed nasal polyp cells.
Journal: Arzneimittel-Forschung 20020101
Title: Pharmacokinetic profile of zafirlukast.
Journal: Clinical pharmacokinetics 20020101
Title: Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine.
Journal: Clinical pharmacokinetics 20020101
Title: [Comparative antihistamine and anti-allergic effects of various antihistamine preparations].
Journal: Terapevticheskii arkhiv 20020101
Title: Do standard doses of frequently prescribed drugs cause preventable adverse effects in women?
Journal: Journal of the American Medical Women's Association (1972) 20020101
Title: A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020101
Title: An evaluation of the effects of high-dose fexofenadine on the central nervous system: a double-blind, placebo-controlled study in healthy volunteers.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020101
Title: Drug eruption and liver injury caused by terfenadine and oxatomide.
Journal: European journal of dermatology : EJD 20020101
Title: Potential cardiac toxicity of H1-antihistamines.
Journal: Clinical allergy and immunology 20020101
Title: [Risk of drug interactions. Combinations of drugs associated with ventricular arrhythmias].
Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20020101
Title: [Effect of tedin on clinical and allergic indices of viral hepatitis in the presence of giardiasis].
Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20020101
Title: Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity.
Journal: Journal of cellular biochemistry 20020101
Title: Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE.
Journal: Rapid communications in mass spectrometry : RCM 20020101
Title: Effects of terfenadine and diphenhydramine on the CYP2D6 activity in healthy volunteers.
Journal: European journal of drug metabolism and pharmacokinetics 20020101
Title: The use of antihistamines in safety-critical jobs: a meeting report.
Journal: Current medical research and opinion 20020101
Title: Rapidly distinguishing reversible and irreversible CYP450 inhibitors by using fluorometric kinetic analyses.
Journal: European journal of drug metabolism and pharmacokinetics 20020101
Title: Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.
Journal: Drugs under experimental and clinical research 20020101
Title: Application of microtiter plate assay to evaluate inhibitory effects of various compounds on nine cytochrome P450 isoforms and to estimate their inhibition patterns.
Journal: Drug metabolism and pharmacokinetics 20020101
Title: Effects of serum albumin and liver cytosol on CYP2C9- and CYP3A4-mediated drug metabolism.
Journal: Drug metabolism and pharmacokinetics 20020101
Title: pH-metric solubility. 3. Dissolution titration template method for solubility determination.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20011201
Title: Second generation antihistamines in the treatment of seasonal allergic rhinitis due to Parietaria and cypress pollen.
Journal: Pharmacological research 20011201
Title: Histamine and the classic antihistamines.
Journal: Drug news & perspectives 20011201
Title: Assay of terfenadine in pharmaceutical formulation and human plasma by adsorptive stripping voltammetry.
Journal: Journal of pharmaceutical and biomedical analysis 20011101
Title: Fexofenadine reduces nasal congestion in perennial allergic rhinitis.
Journal: Allergy 20011101
Title: Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs).
Journal: Biochemical pharmacology 20011101
Title: [3H]dofetilide binding to HERG transfected membranes: a potential high throughput preclinical screen.
Journal: European journal of pharmacology 20011026
Title: An amino acid residue whose change by mutation affects drug binding to the HERG channel.
Journal: FEBS letters 20011012
Title: Effects of a new antiallergic drug, VUF-K-8788, on infiltration of lung parenchyma by eosinophils in guinea pigs and eosinophil-adhesion to human umbilical vein endothelial cells (HUVEC).
Journal: Biological & pharmaceutical bulletin 20011001
Title: The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis.
Journal: The American journal of managed care 20011001
Title: Development and evaluation of high throughput functional assay methods for HERG potassium channel.
Journal: Journal of biomolecular screening 20011001
Title: Involvement of thromboxane A2 and peptide leukotrienes in early and late phase nasal blockage in a guinea pig model of allergic rhinitis.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010901
Title: Pharmacological characterization of the leukocyte kinetics after intranasal antigen challenge in a guinea pig model of allergic rhinitis.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010901
Title: Terfenadine-beta-Cyclodextrin inclusion complex with antihistaminic activity enhancement.
Journal: Drug development and industrial pharmacy 20010901
Title: Ugly wait at the counter. Insurer pushes to make allergy drugs nonprescription.
Journal: Modern healthcare 20010806
Title: Effects of supratherapeutic doses of ebastine and terfenadine on the QT interval.
Journal: British journal of clinical pharmacology 20010801
Title: Identification of functionally variant MDR1 alleles among European Americans and African Americans.
Journal: Clinical pharmacology and therapeutics 20010801
Title: Assessing the effect of intranasal steroids on growth.
Journal: The Journal of allergy and clinical immunology 20010701
Title: Safety of fexofenadine in children treated for seasonal allergic rhinitis.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010701
Title: Evaluation of the safety of fexofenadine from experience gained in general practice use in England in 1997.
Journal: European journal of clinical pharmacology 20010701
Title: [Effect of olopatadine hydrochloride, a novel antiallergic agent, on the QT interval in dogs].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010601
Title: [Seasonal allergic rhinitis. Nasal obstruction can also beh improved].
Journal: MMW Fortschritte der Medizin 20010503
Title: The canine Purkinje fiber: an in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis.
Journal: Journal of cardiovascular pharmacology 20010501
Title: Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol.
Journal: American journal of respiratory and critical care medicine 20010501
Title: Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis.
Journal: International archives of allergy and immunology 20010501
Title: A descriptive analysis of the use and cost of new-generation antihistamines in the treatment of allergic rhinitis: a retrospective database analysis.
Journal: The American journal of managed care 20010501
Title: VUF-K-8788, a periphery-selective histamine H1 antagonist with anti-pruritic activities.
Journal: Japanese journal of pharmacology 20010501
Title: Roles of mast cells and histamine in mosquito bite-induced allergic itch-associated responses in mice.
Journal: Japanese journal of pharmacology 20010501
Title: Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010501
Title: Newer antihistamines.
Journal: The Medical letter on drugs and therapeutics 20010430
Title: Uptake and efflux of the peptidic delta-opioid receptor agonist.
Journal: Neuroscience letters 20010406
Title: Problems of heart rate correction in assessment of drug-induced QT interval prolongation.
Journal: Journal of cardiovascular electrophysiology 20010401
Title: Twenty-four hours of activity of cetirizine and fexofenadine in the skin.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010401
Title: Drug-induced cholestasis.
Journal: Seminars in gastrointestinal disease 20010401
Title: Skin concentrations of H1-receptor antagonists.
Journal: The Journal of allergy and clinical immunology 20010301
Title: Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation.
Journal: Clinical pharmacology and therapeutics 20010301
Title: The effect of rifampin administration on the disposition of fexofenadine.
Journal: Clinical pharmacology and therapeutics 20010301
Title: Effect of hydroxyzine on the transport of etoposide in rat small intestine.
Journal: Anti-cancer drugs 20010301
Title: Fexofenadine hydrochloride--a new anti-histaminic drug.
Journal: The Israel Medical Association journal : IMAJ 20010301
Title: Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study.
Journal: Clinical therapeutics 20010301
Title: Role of mast cells in antigen-induced airway inflammation and bronchial hyperresponsiveness in rats.
Journal: Japanese journal of pharmacology 20010301
Title: Inhibition of human CYP1A2 activity in vitro by methylxanthines: potent competitive inhibition by 8-phenyltheophylline.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010301
Title: Fixed solar urticaria to visible light successfully treated with fexofenadine.
Journal: Photodermatology, photoimmunology & photomedicine 20010201
Title: Absence of nasal mucosal atrophy with fluticasone aqueous nasal spray.
Journal: Archives of otolaryngology--head & neck surgery 20010201
Title: Involvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadine.
Journal: British journal of clinical pharmacology 20010201
Title: Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20010201
Title: Premedication with antihistamines may enhance efficacy of specific-allergen immunotherapy.
Journal: The Journal of allergy and clinical immunology 20010101
Title: Comparison of montelukast and fexofenadine for chronic idiopathic urticaria.
Journal: Archives of dermatology 20010101
Title: Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010101
Title: Safety of antihistamines in children.
Journal: Drug safety 20010101
Title: Design, synthesis and antihistaminic (H1)activity of some condensed 2-(substituted)arylaminoethylpyrimidin-4(3H)-ones.
Journal: Arzneimittel-Forschung 20010101
Title: Histamine-induced activation of human lung macrophages.
Journal: International archives of allergy and immunology 20010101
Title: Saquinavir soft gelatin capsule: a comparative safety review.
Journal: Drug safety 20010101
Title: Evaluation of drug-induced QT interval prolongation: implications for drug approval and labelling.
Journal: Drug safety 20010101
Title: Pharmacokinetic/pharmacodynamic assessment of the effects of E4031, cisapride, terfenadine and terodiline on monophasic action potential duration in dog.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010101
Title: [The effect of second generation histamine antagonists on the heart].
Journal: Pneumonologia i alergologia polska 20010101
Title: Delusion of worm infestation associated with clarithromycin in a patient on peritoneal dialysis.
Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101
Title: Dissociable effects of histamine H1 antagonists on reaction-time performance in rats.
Journal: Pharmacology, biochemistry, and behavior 20010101
Title: Impact of rhinitis on airway inflammation: biological and therapeutic implications.
Journal: Respiratory research 20010101
Title: Effect of oxatomide, an antiallergic agent, on QT interval in dogs.
Journal: Arzneimittel-Forschung 20010101
Title: [Efficacy and safety of fexofenadine and cetirizine in the treatment of allergic rhinitis].
Journal: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20010101
Title: Antihistamines and the torsade de point in children with allergic rhinitis.
Journal: European review for medical and pharmacological sciences 20010101
Title: Emerging role of drug interaction studies in drug development: the good, the bad, and the unknown.
Journal: Psychopharmacology bulletin 20010101
Title: Pharmacological blockade of ERG K(+) channels and Ca(2+) influx through store-operated channels exerts opposite effects on intracellular Ca(2+) oscillations in pituitary GH(3) cells.
Journal: Molecular pharmacology 20001101
Title: A structural basis for drug-induced long QT syndrome.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20001024
Title: Mechanism of terfenadine block of ATP-sensitive K(+) channels.
Journal: British journal of pharmacology 20000801
Title: Redox state dependency of HERGS631C channel pharmacology: relation to C-type inactivation.
Journal: FEBS letters 20000526
Title: Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20000501
Title: Sedation with 'non-sedating' antihistamines: four prescription-event monitoring studies in general practice.
Journal: BMJ (Clinical research ed.) 20000429
Title: Severe cardiac arrhythmia on fexofenadine?
Journal: Prescrire international 20000201
Title: Loratadine blockade of K(+) channels in human heart: comparison with terfenadine under physiological conditions.
Journal: The Journal of pharmacology and experimental therapeutics 20000101
Title: Antiallergic effects of H1-receptor antagonists.
Journal: Allergy 20000101
Title: Specific inhibition of TH2-type cytokine production from human peripheral T cells by terfenadine in vitro.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 19990901
Title: Fexofenadine and prolonged QT intervals.
Journal: Nursing 19990901
Title: Epinastine, a nonsedating histamine H1 receptor antagonist, has a negligible effect on HERG channel.
Journal: European journal of pharmacology 19990625
Title: Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole.
Journal: Journal of cardiovascular electrophysiology 19990601
Title: Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers.
Journal: Pharmaceutical research 19990501
Title: QT lengthening and life-threatening arrhythmias associated with fexofenadine.
Journal: Lancet (London, England) 19990320
Title: Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs.
Journal: British journal of clinical pharmacology 19990301
Title: Blockade of HERG and Kv1.5 by ketoconazole.
Journal: The Journal of pharmacology and experimental therapeutics 19980801
Title: Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines.
Journal: Molecular pharmacology 19980701
Title: Fexofenadine.
Journal: Drugs 19980201
Title: A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.
Journal: FEBS letters 19971103
Title: [Excessive terfenadine level due to drinking grapefruit juice].
Journal: Nederlands tijdschrift voor geneeskunde 19971011
Title: Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin.
Journal: Cell biology and toxicology 19970701
Title: Comparative effects of nonsedating histamine H1 receptor antagonists, ebastine and terfenadine, on human Kv1.5 channels.
Journal: European journal of pharmacology 19970520
Title: [Syncopes during simultaneous use of terfenadine and itraconazole].
Journal: Nederlands tijdschrift voor geneeskunde 19970510
Title: A comparative pharmacokinetic-pharmacodynamic study of the electrocardiographic effects of epinastine and terfenadine in rats.
Journal: The Journal of pharmacy and pharmacology 19970401
Title: Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism.
Journal: Drug metabolism and disposition: the biological fate of chemicals 19970201
Title: Torsades de pointes from terfenadine and sotalol given in combination.
Journal: Pacing and clinical electrophysiology : PACE 19961001
Title: Terfenadine induced coma mimicking structural brain disease.
Journal: The Journal of the Association of Physicians of India 19961001
Title: Terfenadine-induced cholestatic hepatitis.
Journal: Lancet (London, England) 19960824
Title: HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine.
Journal: Circulation 19960815
Title: Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole.
Journal: FEBS letters 19960429
Title: Terfenadine overdose induced polymorphous ventricular tachycardia.
Journal: Indian pediatrics 19951001
Title: Probable terfenadine-fluoxetine-associated cardiac toxicity.
Journal: The Annals of pharmacotherapy 19950901
Title: Effect of terfenadine and budesonide on nasal symptoms, olfaction, and nasal airway patency following allergen challenge.
Journal: Allergy 19950801
Title: [Ventricular arrhythmia induced by terfenadine treatment].
Journal: Medicina clinica 19950204
Title: Torsades de pointes associated with terfenadine in a case of liver cirrhosis and hepatocellular carcinoma.
Journal: Internal medicine (Tokyo, Japan) 19950201
Title: Torsades de pointes induced by erythromycin and terfenadine.
Journal: The American journal of emergency medicine 19941101
Title: Torsades de pointes ventricular tachycardia associated with terfenadine and paracetamol self medication.
Journal: The New Zealand medical journal 19941012
Title: Torsade de pointes induced by terfenadine in a patient with long QT syndrome.
Journal: Journal of electrocardiology 19941001
Title: Urinary retention as a result of administration of terfenadine.
Journal: The Journal of allergy and clinical immunology 19940601
Title: Benefit/risk ratio of the antihistamines (H1-receptor antagonists) terfenadine and chlorpheniramine in children.
Journal: The Journal of pediatrics 19940601
Title: Risk of developing life-threatening ventricular arrhythmia associated with tefenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine.
Journal: The American journal of cardiology 19940215
Title: Characteristics of P388/VMDRC.04, a simple, sensitive model for studying P-glycoprotein antagonists.
Journal: Cancer research 19940201
Title: Drug-induced torsades de pointes: a possible interaction of terfenadine and erythromycin.
Journal: The Annals of pharmacotherapy 19940201
Title: [Torsades de pointes caused by the association of terfenadine and erythromycin].
Journal: Annales de medecine interne 19940101
Title: Torsades de pointes associated with astemizole (Hismanal) therapy.
Journal: Archives of internal medicine 19931213
Title: Potential terfenadine-fluoxetine interaction.
Journal: The Annals of pharmacotherapy 19931101
Title: Public health problems and the rapid estimation of the size of the population at risk. Torsades de pointes and the use of terfenadine and astemizole in The Netherlands.
Journal: Pharmacy world & science : PWS 19931015
Title: Syncope and cardiac arrhythmia due to an interaction between itraconazole and terfenadine.
Journal: The American journal of medicine 19931001
Title: Is QT interval prolongation harmful? A regulatory perspective.
Journal: The American journal of cardiology 19930826
Title: The effect of antihistamines on the immediate allergic response: a comparative review.
Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 19930601
Title: Cutaneous IgE-mediated inflammatory lesion size is inhibited by an H1 antagonist (terfenadine) while mediator release is unaffected in vivo and in vitro.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 19930501
Title: [A new cause of torsades de pointes: combination of terfenadine and troleandomycin].
Journal: Annales de cardiologie et d'angeiologie 19930501
Title: Terfenadine-induced tremor.
Journal: Annals of neurology 19930201
Title: Torsades de pointes after terfenadine-itraconazole interaction.
Journal: BMJ (Clinical research ed.) 19930116
Title: Erythromycin and ketoconazole (Nizoral) associated with terfenadine (Seldane)-induced ventricular arrhythmias.
Journal: General dentistry 19930101
Title: The effect of terfenadine on the immediate and late-phase reactions mediated by immunoglobulin E.
Journal: International archives of allergy and immunology 19930101
Title: [Treatment with terfenadine and ketoconazole or itraconazole can cause torsades de pointes ventricular tachycardia].
Journal: Duodecim; laaketieteellinen aikakauskirja 19930101
Title: Torsades de Pointes after treatment with terfenadine and ketoconazole.
Journal: European heart journal 19920701
Title: Terfenadine use associated with ventricular dysrhythmias.
Journal: Critical care nurse 19920201
Title: Torsades de pointes occurring in association with terfenadine use.
Journal: JAMA 19901205
Title: Antihistaminic activity and side effect profile of epinastine and terfenadine in healthy volunteers.
Journal: International journal of clinical pharmacology, therapy, and toxicology 19901201
Title: Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation.
Journal: Annals of allergy 19900201
Title: Prolongation of simple and choice reaction times in a double-blind comparison of twice-daily hydroxyzine versus terfenadine.
Journal: The Journal of allergy and clinical immunology 19890901
Title: [Therapy of acute and chronic urticaria and of Quincke's edema].
Journal: Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis 19890516
Title: Comparative study of astemizole and terfenadine in the treatment of chronic idiopathic urticaria. A randomized double-blind study of 40 patients.
Journal: Annals of allergy 19890401
Title: 'In vivo' and 'in vitro' evaluation of four antihistamines (astemizole, azatadine, mequitazine, terfenadine).
Journal: Allergologia et immunopathologia 19890101
Title: A comparison of acrivastine versus terfenadine and placebo in the treatment of chronic idiopathic urticaria.
Journal: The Journal of international medical research 19890101
Title: Evaluation of the antimuscarinic activity of atropine, terfenadine and mequitazine in healthy volunteers.
Journal: British journal of clinical pharmacology 19880101
Title: Pharmacologic analysis of LY188695 (KB-2413), 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate, a potent histamine1 receptor antagonist.
Journal: Agents and actions 19870201
Title: Double-blind comparison of astemizole and terfenadine in the treatment of chronic urticaria.
Journal: Pharmatherapeutica 19860101
Title: [Comparison of astemizole and terfenadine in the treatment of chronic urticaria. A randomized double-blind study of 40 patients].
Journal: Zeitschrift fur Hautkrankheiten 19850101
Title: Clinical pharmacokinetics of H1-receptor antagonists (the antihistamines).
Journal: Clinical pharmacokinetics 19850101
