300-39-0,MFCD00150275
Catalog No.:AA007JS1

300-39-0 | 3,5-Diiodo-L-tyrosine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$29.00   $20.00
- +
5g
98%
in stock  
$34.00   $24.00
- +
10g
≥98%
in stock  
$42.00   $29.00
- +
25g
98%
in stock  
$95.00   $67.00
- +
50g
≥98%
in stock  
$153.00   $107.00
- +
100g
98%
in stock  
$261.00   $183.00
- +
500g
98%
in stock  
$926.00 $648.00
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA007JS1
Chemical Name:
3,5-Diiodo-L-tyrosine
CAS Number:
300-39-0
Molecular Formula:
C9H9I2NO3
Molecular Weight:
432.9816
MDL Number:
MFCD00150275
SMILES:
OC(=O)[C@H](Cc1cc(I)c(c(c1)I)O)N
Properties
Computed Properties
 
Complexity:
227  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-0.5  

Literature

Title: Speciation of the bio-available iodine and bromine forms in edible seaweed by high performance liquid chromatography hyphenated with inductively coupled plasma-mass spectrometry.

Journal: Analytica chimica acta 20121001

Title: Iodotyrosine deiodinase defect identified via genome-wide approach.

Journal: The Journal of clinical endocrinology and metabolism 20120701

Title: Differentiation of enantiomeric drugs by iodo-substituted L-amino acid references under electrospray ionization mass spectrometric conditions.

Journal: Rapid communications in mass spectrometry : RCM 20120615

Title: Development of anion-exchange/reversed-phase high performance liquid chromatography-inductively coupled plasma-mass spectrometry methods for the speciation of bio-available iodine and bromine from edible seaweed.

Journal: Journal of chromatography. A 20120504

Title: The site-specific basicity of thyroid hormones and their precursors as regulators of their biological functions.

Journal: Journal of pharmaceutical and biomedical analysis 20120305

Title: Multiple tyrosine metabolites are GPR35 agonists.

Journal: Scientific reports 20120101

Title: Thyroidology over the ages.

Journal: Indian journal of endocrinology and metabolism 20110701

Title: Iodine and pregnancy.

Journal: Journal of thyroid research 20110101

Title: Efficient use and recycling of the micronutrient iodide in mammals.

Journal: Biochimie 20100901

Title: Thyroid hormones and D-aspartic acid, D-aspartate oxidase, D-aspartate racemase, H2O2, and ROS in rats and mice.

Journal: Chemistry & biodiversity 20100601

Title: Effects of drugs on the efficacy of radioiodine (|) therapy in hyperthyroid patients.

Journal: Archives of medical science : AMS 20100301

Title: The halogenated metabolism of brown algae (Phaeophyta), its biological importance and its environmental significance.

Journal: Marine drugs 20100101

Title: Expression pattern of iodotyrosine dehalogenase 1 (DEHAL1) during chick ontogeny.

Journal: The International journal of developmental biology 20100101

Title: HPLC-MS analysis of iodotyrosines produced by sample hydrolysis: A simple method for monitoring iodinated casein in feed premixes.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091215

Title: Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.

Journal: The Journal of biological chemistry 20090717

Title: The impact of iodine excess on thyroid hormone biosynthesis and metabolism in rats.

Journal: Biological trace element research 20090701

Title: Deciphering the peptide iodination code: influence on subsequent gas-phase radical generation with photodissociation ESI-MS.

Journal: Journal of the American Society for Mass Spectrometry 20090601

Title: Competitive inhibition of thyroidal uptake of dietary iodide by perchlorate does not describe perturbations in rat serum total T4 and TSH.

Journal: Environmental health perspectives 20090501

Title: Localization and enzyme activity of iodotyrosine dehalogenase 1 during metamorphosis of frog Microhyla ornata.

Journal: Annals of the New York Academy of Sciences 20090401

Title: Molecular characterization of iodotyrosine dehalogenase deficiency in patients with hypothyroidism.

Journal: The Journal of clinical endocrinology and metabolism 20081201

Title: Specific electrochemical iodination of horse heart myoglobin at tyrosine 103 as determined by Fourier transform ion cyclotron resonance mass spectrometry.

Journal: Archives of biochemistry and biophysics 20080601

Title: Keeping the culture alive: the laboratory technician in mid-twentieth-century British medical research.

Journal: Notes and records of the Royal Society of London 20080320

Title: Interaction of pepsin with aromatic amino acids and their derivatives immobilized to Sepharose.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215

Title: Chiral discrimination of D- and L-amino acids using iodinated tyrosines as chiral references: effect of iodine substituent.

Journal: Journal of the American Society for Mass Spectrometry 20070801

Title: Flexible mapping of homology onto structure with homolmapper.

Journal: BMC bioinformatics 20070101

Title: Protein radical formation on thyroid peroxidase during turnover as detected by immuno-spin trapping.

Journal: Free radical biology & medicine 20060801

Title: Cloning and characterization of a novel isoform of iodotyrosine dehalogenase 1 (DEHAL1) DEHAL1C from human thyroid: comparisons with DEHAL1 and DEHAL1B.

Journal: Thyroid : official journal of the American Thyroid Association 20060801

Title: [Iodide organification defect].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060528

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Identification and quantitation of iodotyrosines and iodothyronines in hydrolysate of iodinated casein by capillary electrophoresis.

Journal: Talanta 20060315

Title: Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions.

Journal: Bioinorganic chemistry and applications 20060101

Title: Interaction of thioamides, selenoamides, and amides with diiodine.

Journal: Bioinorganic chemistry and applications 20060101

Title: Synthesis of the side chain cross-linked tyrosine oligomers dityrosine, trityrosine, and pulcherosine.

Journal: The Journal of organic chemistry 20050902

Title: Short-term stimulation of lipogenesis by 3,5-L-diiodothyronine in cultured rat hepatocytes.

Journal: Endocrinology 20050901

Title: Preparation and testing of stationary phases and modified capillaries for affinity chromatography and affinity capillary electrophoresis of pepsin.

Journal: Journal of chromatography. A 20050819

Title: Analysis of thyroglobulin iodination by tandem mass spectrometry using immonium ions of monoiodo- and diiodo-tyrosine.

Journal: Proteomics 20050201

Title: Development of a validated HPLC method for the determination of iodotyrosines and iodothyronines in pharmaceuticals and biological samples using solid phase extraction.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050105

Title: Immunogenicity of a brominated protein and successive establishment of a monoclonal antibody to dihalogenated tyrosine.

Journal: Free radical biology & medicine 20050101

Title: Sensitized photooxidation of thyroidal hormones. Evidence for heavy atom effect on singlet molecular oxygen [O2(1Deltag)]-mediated photoreactions.

Journal: Photochemistry and photobiology 20050101

Title: Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide close to the thyroglobulin iodination site.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041001

Title: Studies on experimental iodine allergy: 1. Antigen recognition of guinea pig anti-iodine antibody.

Journal: The Journal of toxicological sciences 20040501

Title: Studies on experimental iodine allergy: 3. Low molecular weight elicitogenic antigens of iodine allergy.

Journal: The Journal of toxicological sciences 20040501

Title: Design of a pH-sensitive pore-forming peptide with improved performance.

Journal: The journal of peptide research : official journal of the American Peptide Society 20040101

Title: Aromatic amino acids and their derivatives as ligands for the isolation of aspartic proteinases.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020425

Title: Iodine species and the endocrine system: thyroid hormone levels in adult Danio rerio and developing Xenopus laevis.

Journal: Analytical and bioanalytical chemistry 20020201

Title: Update on intrathyroidal iodine metabolism.

Journal: Thyroid : official journal of the American Thyroid Association 20010501

Title: Chemotactic selection with insulin, di-iodotyrosine and histamine alters the phagocytotic responsiveness of Tetrahymena.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010401

Title: Affinity chromatography of porcine pepsin on different types of immobilized 3,5-diiodo-L-tyrosine.

Journal: Journal of chromatography. A 20010316

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SDS
Tags:300-39-0 Molecular Formula|300-39-0 MDL|300-39-0 SMILES|300-39-0 3,5-Diiodo-L-tyrosine
Catalog No.: AA007JS1
300-39-0,MFCD00150275
300-39-0 | 3,5-Diiodo-L-tyrosine
Pack Size: 1g
Purity: 98%
in stock
$29.00 $20.00
Pack Size: 5g
Purity: 98%
in stock
$34.00 $24.00
Pack Size: 10g
Purity: ≥98%
in stock
$42.00 $29.00
Pack Size: 25g
Purity: 98%
in stock
$95.00 $67.00
Pack Size: 50g
Purity: ≥98%
in stock
$153.00 $107.00
Pack Size: 100g
Purity: 98%
in stock
$261.00 $183.00
Pack Size: 500g
Purity: 98%
in stock
$926.00 $648.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA007JS1
Chemical Name: 3,5-Diiodo-L-tyrosine
CAS Number: 300-39-0
Molecular Formula: C9H9I2NO3
Molecular Weight: 432.9816
MDL Number: MFCD00150275
SMILES: OC(=O)[C@H](Cc1cc(I)c(c(c1)I)O)N
Properties
Complexity: 227  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 15  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -0.5  
Literature fold

Title: Speciation of the bio-available iodine and bromine forms in edible seaweed by high performance liquid chromatography hyphenated with inductively coupled plasma-mass spectrometry.

Journal: Analytica chimica acta20121001

Title: Iodotyrosine deiodinase defect identified via genome-wide approach.

Journal: The Journal of clinical endocrinology and metabolism20120701

Title: Differentiation of enantiomeric drugs by iodo-substituted L-amino acid references under electrospray ionization mass spectrometric conditions.

Journal: Rapid communications in mass spectrometry : RCM20120615

Title: Development of anion-exchange/reversed-phase high performance liquid chromatography-inductively coupled plasma-mass spectrometry methods for the speciation of bio-available iodine and bromine from edible seaweed.

Journal: Journal of chromatography. A20120504

Title: The site-specific basicity of thyroid hormones and their precursors as regulators of their biological functions.

Journal: Journal of pharmaceutical and biomedical analysis20120305

Title: Multiple tyrosine metabolites are GPR35 agonists.

Journal: Scientific reports20120101

Title: Thyroidology over the ages.

Journal: Indian journal of endocrinology and metabolism20110701

Title: Iodine and pregnancy.

Journal: Journal of thyroid research20110101

Title: Efficient use and recycling of the micronutrient iodide in mammals.

Journal: Biochimie20100901

Title: Thyroid hormones and D-aspartic acid, D-aspartate oxidase, D-aspartate racemase, H2O2, and ROS in rats and mice.

Journal: Chemistry & biodiversity20100601

Title: Effects of drugs on the efficacy of radioiodine (|) therapy in hyperthyroid patients.

Journal: Archives of medical science : AMS20100301

Title: The halogenated metabolism of brown algae (Phaeophyta), its biological importance and its environmental significance.

Journal: Marine drugs20100101

Title: Expression pattern of iodotyrosine dehalogenase 1 (DEHAL1) during chick ontogeny.

Journal: The International journal of developmental biology20100101

Title: HPLC-MS analysis of iodotyrosines produced by sample hydrolysis: A simple method for monitoring iodinated casein in feed premixes.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20091215

Title: Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.

Journal: The Journal of biological chemistry20090717

Title: The impact of iodine excess on thyroid hormone biosynthesis and metabolism in rats.

Journal: Biological trace element research20090701

Title: Deciphering the peptide iodination code: influence on subsequent gas-phase radical generation with photodissociation ESI-MS.

Journal: Journal of the American Society for Mass Spectrometry20090601

Title: Competitive inhibition of thyroidal uptake of dietary iodide by perchlorate does not describe perturbations in rat serum total T4 and TSH.

Journal: Environmental health perspectives20090501

Title: Localization and enzyme activity of iodotyrosine dehalogenase 1 during metamorphosis of frog Microhyla ornata.

Journal: Annals of the New York Academy of Sciences20090401

Title: Molecular characterization of iodotyrosine dehalogenase deficiency in patients with hypothyroidism.

Journal: The Journal of clinical endocrinology and metabolism20081201

Title: Specific electrochemical iodination of horse heart myoglobin at tyrosine 103 as determined by Fourier transform ion cyclotron resonance mass spectrometry.

Journal: Archives of biochemistry and biophysics20080601

Title: Keeping the culture alive: the laboratory technician in mid-twentieth-century British medical research.

Journal: Notes and records of the Royal Society of London20080320

Title: Interaction of pepsin with aromatic amino acids and their derivatives immobilized to Sepharose.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20080215

Title: Chiral discrimination of D- and L-amino acids using iodinated tyrosines as chiral references: effect of iodine substituent.

Journal: Journal of the American Society for Mass Spectrometry20070801

Title: Flexible mapping of homology onto structure with homolmapper.

Journal: BMC bioinformatics20070101

Title: Protein radical formation on thyroid peroxidase during turnover as detected by immuno-spin trapping.

Journal: Free radical biology & medicine20060801

Title: Cloning and characterization of a novel isoform of iodotyrosine dehalogenase 1 (DEHAL1) DEHAL1C from human thyroid: comparisons with DEHAL1 and DEHAL1B.

Journal: Thyroid : official journal of the American Thyroid Association20060801

Title: [Iodide organification defect].

Journal: Nihon rinsho. Japanese journal of clinical medicine20060528

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Identification and quantitation of iodotyrosines and iodothyronines in hydrolysate of iodinated casein by capillary electrophoresis.

Journal: Talanta20060315

Title: Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions.

Journal: Bioinorganic chemistry and applications20060101

Title: Interaction of thioamides, selenoamides, and amides with diiodine.

Journal: Bioinorganic chemistry and applications20060101

Title: Synthesis of the side chain cross-linked tyrosine oligomers dityrosine, trityrosine, and pulcherosine.

Journal: The Journal of organic chemistry20050902

Title: Short-term stimulation of lipogenesis by 3,5-L-diiodothyronine in cultured rat hepatocytes.

Journal: Endocrinology20050901

Title: Preparation and testing of stationary phases and modified capillaries for affinity chromatography and affinity capillary electrophoresis of pepsin.

Journal: Journal of chromatography. A20050819

Title: Analysis of thyroglobulin iodination by tandem mass spectrometry using immonium ions of monoiodo- and diiodo-tyrosine.

Journal: Proteomics20050201

Title: Development of a validated HPLC method for the determination of iodotyrosines and iodothyronines in pharmaceuticals and biological samples using solid phase extraction.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20050105

Title: Immunogenicity of a brominated protein and successive establishment of a monoclonal antibody to dihalogenated tyrosine.

Journal: Free radical biology & medicine20050101

Title: Sensitized photooxidation of thyroidal hormones. Evidence for heavy atom effect on singlet molecular oxygen [O2(1Deltag)]-mediated photoreactions.

Journal: Photochemistry and photobiology20050101

Title: Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide close to the thyroglobulin iodination site.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20041001

Title: Studies on experimental iodine allergy: 1. Antigen recognition of guinea pig anti-iodine antibody.

Journal: The Journal of toxicological sciences20040501

Title: Studies on experimental iodine allergy: 3. Low molecular weight elicitogenic antigens of iodine allergy.

Journal: The Journal of toxicological sciences20040501

Title: Design of a pH-sensitive pore-forming peptide with improved performance.

Journal: The journal of peptide research : official journal of the American Peptide Society20040101

Title: Aromatic amino acids and their derivatives as ligands for the isolation of aspartic proteinases.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20020425

Title: Iodine species and the endocrine system: thyroid hormone levels in adult Danio rerio and developing Xenopus laevis.

Journal: Analytical and bioanalytical chemistry20020201

Title: Update on intrathyroidal iodine metabolism.

Journal: Thyroid : official journal of the American Thyroid Association20010501

Title: Chemotactic selection with insulin, di-iodotyrosine and histamine alters the phagocytotic responsiveness of Tetrahymena.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP20010401

Title: Affinity chromatography of porcine pepsin on different types of immobilized 3,5-diiodo-L-tyrosine.

Journal: Journal of chromatography. A20010316

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