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10420-73-2,MFCD00209560
Catalog No.:AA008R23

10420-73-2 | 6-Chloroflavone

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1g
≥ 97% (HPLC)
in stock  
$105.00   $73.00
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5g
≥ 97% (HPLC)
in stock  
$336.00   $235.00
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25g
≥ 97% (HPLC)
in stock  
$1,063.00   $744.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA008R23
Chemical Name:
6-Chloroflavone
CAS Number:
10420-73-2
Molecular Formula:
C15H9ClO2
Molecular Weight:
256.6838
MDL Number:
MFCD00209560
SMILES:
Clc1ccc2c(c1)c(=O)cc(o2)c1ccccc1
Properties
Computed Properties
 
Complexity:
358  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
4.6  

Downstream Synthesis Route

[1]Kabalka,GeorgeW.;Mereddy,ArjunR.[TetrahedronLetters,2005,vol.46,#37,p.6315-6317]

[2]Thorat,NitinM.;Kote,SantoshR.;Thopate,ShankarR.[LettersinOrganicChemistry,2014,vol.11,#8,p.601-605]

[3]Thorat,NitinM.;Dengale,RohitA.;Thopate,ShankarR.;Rohokale,SandeepV.[LettersinOrganicChemistry,2015,vol.12,#8,p.574-583]

[4]Pérez,María;Ruiz,Diego;Autino,Juan;Sathicq,Angel;Romanelli,Gustavo[ComptesRendusChimie,2016,vol.19,#5,p.551-555]

[5]Dengale,RohitArvind;Thorat,NitinMadhu;Thopate,ShankarRamchandra[LettersinOrganicChemistry,2016,vol.13,#10,p.734-741]

[6]Unde,PradipJ.;Thorat,NitinM.;Patil,LimbrajR.[AsianJournalofChemistry,2019,vol.31,#5,p.1133-1136]

[7]Locationinpatent:experimentalpartBennardi,DanielO.;Romanelli,GustavoP.;Sathicq,ÁngelG.;Autino,JuanC.;Baronetti,GracielaT.;Thomas,HoracioJ.[AppliedCatalysisA:General,2011,vol.404,#1-2,p.68-73]

[8]Migliorero,MaríaBelénColombo;Palermo,Valeria;Durango,EdwinAlexisAlarcón;Holguín,AídaLuzVilla;Vázquez,PatriciaGraciela;Sathicq,ÁngelGabriel;Romanelli,GustavoPablo[LettersinOrganicChemistry,2018,vol.15,#10,p.826-832]

[9]Bennardi,DanielO.;Romanelli,GustavoP.;Jios,JorgeL.;Vazquez,PatriciaG.;Caceres,CarmenV.;Autino,JuanC.[HeterocyclicCommunications,2007,vol.13,#1,p.77-81]

[10]Sun,Dong-Wei;Zhou,Yong-Yan;Jiang,Min;Nian,Tang;Liu,Jin-Tao[Tetrahedron,2021,vol.91]

[11]Marder,Mariel;Zinczuk,Juan;Colombo,MariaI.;Wasowski,Cristina;Viola,Haydee;Wolfman,Claudia;Medina,JorgeH.;Ruveda,EdmundoA.;Paladini,AlejandroC.[BioorganicandMedicinalChemistryLetters,1997,vol.7,#15,p.2003-2008]

[1]AngewandteChemie-InternationalEdition,2012,vol.51,p.11333-11336,4

[1]OrganicandBiomolecularChemistry,2015,vol.14,p.777-784

[2]BioorganicandMedicinalChemistryLetters,2017,vol.27,p.2613-2616

[1]Molecularcatalysis,2018,vol.452,p.264-270

Literature

Title: Effects of flavone 6-substitutions on GABAA receptors efficacy.

Journal: European journal of pharmacology 20111116

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Structural conformations and vibrational spectral study of chloroflavone with density functional theoretical simulations.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100701

Title: Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.

Journal: Bioorganic & medicinal chemistry letters 20090815

Title: QSAR modeling of the interaction of flavonoids with GABA(A) receptor.

Journal: European journal of medicinal chemistry 20080801

Title: Antitumor activity of some natural flavonoids and synthetic derivatives on various human and murine cancer cell lines.

Journal: Bioorganic & medicinal chemistry 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Chalcones and flavonoids as anti-tuberculosis agents.

Journal: Bioorganic & medicinal chemistry 20020801

Title: Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 19960607

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SDS
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