Home Bromides 1218-80-0
1218-80-0,MFCD00276169
Catalog No.:AA0015Z7

1218-80-0 | 6-Bromoflavone

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1g
≥ 98% (HPLC)
in stock  
$87.00   $61.00
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5g
≥ 98% (HPLC)
in stock  
$180.00   $126.00
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25g
≥ 98% (HPLC)
in stock  
$564.00   $395.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0015Z7
Chemical Name:
6-Bromoflavone
CAS Number:
1218-80-0
Molecular Formula:
C15H9BrO2
Molecular Weight:
301.1348
MDL Number:
MFCD00276169
SMILES:
Brc1ccc2c(c1)c(=O)cc(o2)c1ccccc1
Properties
Properties
 
BP:
421.1±45.0 °C(Predicted)  
Form:
Solid  
MP:
193-196 °C(lit.)  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
358  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
4.7  

Downstream Synthesis Route

[1]Viola,Haydee;Marder,Mariel;Wolfman,Claudia;Wasowski,Cristina;Medina,JorgeH.;Paladini,AlejandroC.[BioorganicandMedicinalChemistryLetters,1997,vol.7,#3,p.373-378]

[1]Kabalka,GeorgeW.;Mereddy,ArjunR.[TetrahedronLetters,2005,vol.46,#37,p.6315-6317]

[2]Pérez,María;Ruiz,Diego;Autino,Juan;Sathicq,Angel;Romanelli,Gustavo[ComptesRendusChimie,2016,vol.19,#5,p.551-555]

[3]Thorat,NitinM.;Sarkate,AniketP.;Lokwani,DeepakK.;Tiwari,ShaileeV.;Azad,Rajaram;Thopate,ShankarR.[MolecularDiversity,2021,vol.25,#2,p.937-948]

[4]Unde,PradipJ.;Thorat,NitinM.;Patil,LimbrajR.[AsianJournalofChemistry,2019,vol.31,#5,p.1133-1136]

[5]Locationinpatent:experimentalpartBennardi,DanielO.;Romanelli,GustavoP.;Sathicq,ÁngelG.;Autino,JuanC.;Baronetti,GracielaT.;Thomas,HoracioJ.[AppliedCatalysisA:General,2011,vol.404,#1-2,p.68-73]

[6]Bennardi,DanielO.;Romanelli,GustavoP.;Jios,JorgeL.;Vazquez,PatriciaG.;Caceres,CarmenV.;Autino,JuanC.[HeterocyclicCommunications,2007,vol.13,#1,p.77-81]

[7]Stanek,Filip;Stodulski,Maciej[TetrahedronLetters,2016,vol.57,#34,p.3841-3843]

[8]Marder,Mariel;Zinczuk,Juan;Colombo,MariaI.;Wasowski,Cristina;Viola,Haydee;Wolfman,Claudia;Medina,JorgeH.;Ruveda,EdmundoA.;Paladini,AlejandroC.[BioorganicandMedicinalChemistryLetters,1997,vol.7,#15,p.2003-2008]

[9]AbdelGhani,SherifB.;Weaver,Louise;Zidan,ZidanH.;Ali,HusseinM.;Keevil,C.William;Brown,RichardC.D.[BioorganicandMedicinalChemistryLetters,2008,vol.18,#2,p.518-522]

[10]Ghani,SherifB.Abdel;Mugisha,PatrickJ.;Wilcox,JulietC.;Gado,EmadA.M.;Medu,ErereO.;Lamb,AndrewJ.;Brown,RichardC.D.[SyntheticCommunications,2013,vol.43,#11,p.1549-1556]

[11]Zhang,Jifa;Tang,Pan;Zou,Ling;Zhang,Jin;Chen,Juncheng;Yang,Chengcan;He,Gu;Liu,Bo;Liu,Jie;Chiang,Cheng-Ming;Wang,Guan;Ye,Tinghong;Ouyang,Liang[JournalofMedicinalChemistry,2021,vol.64,#24,p.18025-18053]

[12]Raiguru,BishnuPrasad;Panda,Jasmine;Mohapatra,Seetaram;Nayak,Sabita[JournalofMolecularStructure,2023,vol.1294]

[1]Locationinpatent:experimentalpartKim,Donghee;Ham,Kyungrok;Hong,Sungwoo[OrganicandBiomolecularChemistry,2012,vol.10,#36,p.7305-7312]

[2]Yang,Liu;Huang,Zhiyan;Li,Gang;Zhang,Wei;Cao,Rui;Wang,Chao;Xiao,Jianliang;Xue,Dong[AngewandteChemie-InternationalEdition,2018,vol.57,#7,p.1968-1972][Angew.Chem.,2018,vol.130,p.1986-1990,5]

1271-51-8    1218-80-0   
(E)-6-ferrocenylvinyl-2-phenyl-chromen-4-one 

[1]Kowalski,Konrad;Koceva-Chy,Aneta;Szczupak,Lukasz;Hikisz,Pawel;Bernasińska,Joanna;Rajnisz,Aleksandra;Solecka,Jolanta;Therrien,Bruno[JournalofOrganometallicChemistry,2013,vol.741-742,#1,p.153-161]

1218-80-0    224311-51-7   
6-tert-butoxy-2-phenyl-4H-chromen-4-one 

[1]Chemistry-AEuropeanJournal,2013,vol.19,p.13658-13662

Literature

Title: Effects of flavone 6-substitutions on GABAA receptors efficacy.

Journal: European journal of pharmacology 20111116

Title: QSAR modeling of the interaction of flavonoids with GABA(A) receptor.

Journal: European journal of medicinal chemistry 20080801

Title: Microwave-assisted synthesis and antimicrobial activities of flavonoid derivatives.

Journal: Bioorganic & medicinal chemistry letters 20080115

Title: Antitumor activity of some natural flavonoids and synthetic derivatives on various human and murine cancer cell lines.

Journal: Bioorganic & medicinal chemistry 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Chalcones and flavonoids as anti-tuberculosis agents.

Journal: Bioorganic & medicinal chemistry 20020801

Title: 3D-QSAR model of flavonoids binding at benzodiazepine site in GABAA receptors.

Journal: Journal of medicinal chemistry 20010607

Title: Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex.

Journal: Journal of medicinal chemistry 19991021

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