Home Other Building Blocks 120210-48-2
120210-48-2,MFCD00865996
Catalog No.:AA008T67

120210-48-2 | TENIDAP

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$100.00   $70.00
- +
10mg
≥98%
in stock  
$175.00   $122.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008T67
Chemical Name:
TENIDAP
CAS Number:
120210-48-2
Molecular Formula:
C14H9ClN2O3S
Molecular Weight:
320.7509
MDL Number:
MFCD00865996
SMILES:
Clc1ccc2c(c1)/C(=C(\c1cccs1)/O)/C(=O)N2C(=O)N
Properties
Computed Properties
 
Complexity:
450  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
3.8  

Literature

Title: Application of the systems chemistry approach on the ammonolysis of 1-ethoxycarbonyl- and 1-phenoxycarbonyl-3-(2-thienyl)oxindoles. A method to predict reactivity.

Journal: The Journal of organic chemistry 20120907

Title: HCO(3)(-)-independent conductance with a mutant Na(+)/HCO(3)(-) cotransporter (SLC4A4) in a case of proximal renal tubular acidosis with hypokalaemic paralysis.

Journal: The Journal of physiology 20120415

Title: Catenarin Prevents Type 1 Diabetes in Nonobese Diabetic Mice via Inhibition of Leukocyte Migration Involving the MEK6/p38 and MEK7/JNK Pathways.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Periodontal status of rheumatoid arthritis patients in khartoum state.

Journal: BMC research notes 20110101

Title: 5-Chloro-indoline-2,3-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Cyclooxygenase Inhibitors, Aspirin and Ibuprofen, Inhibit MHC-restricted Antigen Presentation in Dendritic Cells.

Journal: Immune network 20100601

Title: Opposing effects of tenidap on the volume-regulated anion channel and K(ATP) channel activity in rat pancreatic beta-cells.

Journal: European journal of pharmacology 20100310

Title: PKC{alpha}{beta}{gamma}- and PKC{delta}-dependent endocytosis of NBCe1-A and NBCe1-B in salivary parotid acinar cells.

Journal: American journal of physiology. Cell physiology 20091201

Title: Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish.

Journal: American journal of physiology. Cell physiology 20091001

Title: Expression of the electrogenic Na+-HCO3--cotransporters NBCe1-A and NBCe1-B in rat pancreatic islet cells.

Journal: Endocrine 20090601

Title: Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13.

Journal: Arthritis research & therapy 20090101

Title: Expression of the electrogenic Na+-HCO3--cotransporter NBCe1 in tumoral insulin-producing BRIN-BD11 cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

Title: Therapy for nifedipine-induced gingival overgrowth by Saireito in rats.

Journal: European journal of medical research 20090101

Title: Regulation of superoxide production in neutrophils: role of calcium influx.

Journal: Journal of leukocyte biology 20081101

Title: pH stat studies on bicarbonate secretion in the isolated mouse ileum.

Journal: Biomedical research (Tokyo, Japan) 20071001

Title: Reversible and irreversible interactions of DIDS with the human electrogenic Na/HCO3 cotransporter NBCe1-A: role of lysines in the KKMIK motif of TM5.

Journal: American journal of physiology. Cell physiology 20070501

Title: Activity and potential role of licofelone in the management of osteoarthritis.

Journal: Clinical interventions in aging 20070301

Title: The role of the purinergic P2X7 receptor in inflammation.

Journal: Journal of inflammation (London, England) 20070101

Title: Functional characterization of Cl-/HCO3- exchange in villous cells of the mouse ileum.

Journal: Biomedical research (Tokyo, Japan) 20061201

Title: Transcytosis of Human immunodeficiency virus 1 across the placenta is enhanced by treatment with tumour necrosis factor alpha.

Journal: The Journal of general virology 20060801

Title: Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study.

Journal: Arthritis research & therapy 20060101

Title: Tetra substituted thiophenes as anti-inflammatory agents: exploitation of analogue-based drug design.

Journal: Bioorganic & medicinal chemistry 20051215

Title: P2X(7) receptor: Death or life?

Journal: Purinergic signalling 20050901

Title: Transport properties of the human intestinal anion exchanger DRA (down-regulated in adenoma) in transfected HEK293 cells.

Journal: Pflugers Archiv : European journal of physiology 20050201

Title: The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases.

Journal: Arthritis research & therapy 20050101

Title: Osmotic drug delivery using swellable-core technology.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20040108

Title: Acute regulation of the SLC26A3 congenital chloride diarrhoea anion exchanger (DRA) expressed in Xenopus oocytes.

Journal: The Journal of physiology 20030515

Title: Arthroscopic evaluation of potential structure-modifying drug in osteoarthritis of the knee. A multicenter, randomized, double-blind comparison of tenidap sodium vs piroxicam.

Journal: Osteoarthritis and cartilage 20030301

Title: Are synovial biopsies of diagnostic value?

Journal: Arthritis research & therapy 20030101

Title: Modulation of IL-1beta, IL-6, TNF-alpha and PGE(2) by pharmacological agents in explants of membranes from failed total hip replacement.

Journal: Osteoarthritis and cartilage 20021101

Title: Dose-effect relationships of nonsteroidal anti-inflammatory drugs: a literature review.

Journal: Clinical therapeutics 20020801

Title: Tenidap, an anti-inflammatory agent, inhibits DNA and collagen syntheses, depresses cell proliferation, and lowers intracellular pH in cultured human gingival fibroblasts.

Journal: The Journal of pharmacology and experimental therapeutics 20020201

Title: Tenidap, a novel anti-inflammatory agent, is an opener of the inwardly rectifying K+ channel hKir2.3.

Journal: European journal of pharmacology 20020125

Title: The renal Na-HCO3-cotransporter expressed in Xenopus laevis oocytes: inhibition by tenidap and benzamil and effect of temperature on transport rate and stoichiometry.

Journal: Pflugers Archiv : European journal of physiology 20010801

Title: The renal Na-HCO3-cotransporter expressed in Xenopus laevis oocytes: change in stoichiometry in response to elevation of cytosolic Ca2+ concentration.

Journal: Pflugers Archiv : European journal of physiology 20010801

Title: Modulation by propranolol of the uptake of ethidium bromide by rat submandibular acinar cells exposed to a P2X(7) agonist or to maitotoxin.

Journal: Cellular signalling 20010701

Title: Structure toxicity relationships--how useful are they in predicting toxicities of new drugs?

Journal: Advances in experimental medicine and biology 20010101

Title: Tenidap inhibits replication of the human immunodeficiency virus-1 in cultured cells.

Journal: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 19970101

Title: Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone.

Journal: Arthritis and rheumatism 19951001

Title: In vitro inhibition of leukotriene B4 formation by exogeneous 5-lipoxygenase inhibitors is associated with enhanced generation of 15-hydroxy-eicosatetraenoic acid (15-HETE) by human neutrophils.

Journal: Archives of dermatological research 19880101

Title: Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation. J Pharmacol Exp Ther. 1997 Aug;282(2):1094-101.

Title: Blackburn WD Jr, et al. Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone. Arthritis Rheum. 1995 Oct;38(10):1447-56.

Title: Julio C Chávez, et al. Participation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitation. Biol Reprod. 2012 Jan 19;86(1):1-14.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 120210-48-2
Tags:120210-48-2 Molecular Formula|120210-48-2 MDL|120210-48-2 SMILES|120210-48-2 TENIDAP