Home Other Building Blocks 1186222-89-8
1186222-89-8,MFCD25976779
Catalog No.:AA008T9V

1186222-89-8 | 4SC-202

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$202.00   $141.00
- +
10mg
in stock  
$325.00   $228.00
- +
25mg
98% by HPLC
in stock  
$637.00   $446.00
- +
50mg
in stock  
$861.00   $603.00
- +
100mg
in stock  
$1,308.00   $915.00
- +
500mg
98% by HPLC
in stock  
$5,515.00   $3,861.00
- +
1000mg
98% by HPLC
in stock  
$8,787.00   $6,151.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008T9V
Chemical Name:
4SC-202
CAS Number:
1186222-89-8
Molecular Formula:
C30H29N5O6S2
Molecular Weight:
619.7112
MDL Number:
MFCD25976779
SMILES:
O=C(Nc1ccccc1N)/C=C/c1ccn(c1)S(=O)(=O)c1ccc(cc1)c1cnn(c1)C.Cc1ccc(cc1)S(=O)(=O)O
Properties
Computed Properties
 
Complexity:
981  
Covalently-Bonded Unit Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
7  

Literature

Title: Pinkerneil M, et al. Evaluation of the Therapeutic Potential of the Novel Isotype Specific HDAC Inhibitor 4SC-202 in Urothelial Carcinoma Cell Lines. Target Oncol. 2016 Dec;11(6):783-798.

Title: S.W.Henning, et al. Preclinical characterization of 4SC-202, a noval isotype specific HDAC inhibitor.

Title: Zhijun H, et al. Pre-clinical characterization of 4SC-202, a novel class I HDAC inhibitor, against colorectal cancer cells. Tumour Biol. 2016 Aug;37(8):10257-67.

Title: Fu M, et al. 4SC-202 activates ASK1-dependent mitochondrial apoptosis pathway to inhibit hepatocellular carcinoma cells. Biochem Biophys Res Commun. 2016 Mar 4;471(2):267-73

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SDS
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Tags:1186222-89-8 Molecular Formula|1186222-89-8 MDL|1186222-89-8 SMILES|1186222-89-8 4SC-202