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1228960-69-7,MFCD22683863
Catalog No.:AA009CAP

1228960-69-7 | Mln0905

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$72.00   $50.00
- +
5mg
≥98%
in stock  
$246.00   $172.00
- +
10mg
≥98%
in stock  
$383.00   $268.00
- +
50mg
97%
in stock  
$1,772.00   $1,240.00
- +
100mg
97%
in stock  
$3,145.00   $2,202.00
- +
250mg
97%
in stock  
$7,002.00   $4,902.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA009CAP
Chemical Name:
Mln0905
CAS Number:
1228960-69-7
Molecular Formula:
C24H25F3N6S
Molecular Weight:
486.5557
MDL Number:
MFCD22683863
SMILES:
CN(CCCc1cnc(c(c1)Nc1ncc2c(n1)c1ccc(cc1NC(=S)C2)C(F)(F)F)C)C
Properties
Computed Properties
 
Complexity:
692  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
4.1  

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,2012,vol.55,p.197-208

Literature

Title: Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905).

Journal: Journal of medicinal chemistry 20120112

Title: Duffey MO, et al. Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905). J Med Chem. 2012 Jan 12;55(1):197-208.

Title: Shi JQ, et al. MLN0905, a small-molecule plk1 inhibitor, induces antitumor responses in human models of diffuse large B-cell lymphoma. Mol Cancer Ther. 2012 Sep;11(9):2045-53.

Quotation Request
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SDS
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Tags:1228960-69-7 Molecular Formula|1228960-69-7 MDL|1228960-69-7 SMILES|1228960-69-7 Mln0905
Catalog No.: AA009CAP
1228960-69-7,MFCD22683863
1228960-69-7 | Mln0905
Pack Size： 1mg
Purity： ≥98%
in stock
$72.00 $50.00
Pack Size： 5mg
Purity： ≥98%
in stock
$246.00 $172.00
Pack Size： 10mg
Purity： ≥98%
in stock
$383.00 $268.00
Pack Size： 50mg
Purity： 97%
in stock
$1,772.00 $1,240.00
Pack Size： 100mg
Purity： 97%
in stock
$3,145.00 $2,202.00
Pack Size： 250mg
Purity： 97%
in stock
$7,002.00 $4,902.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA009CAP
Chemical Name: Mln0905
CAS Number: 1228960-69-7
Molecular Formula: C24H25F3N6S
Molecular Weight: 486.5557
MDL Number: MFCD22683863
SMILES: CN(CCCc1cnc(c(c1)Nc1ncc2c(n1)c1ccc(cc1NC(=S)C2)C(F)(F)F)C)C
Properties
Complexity: 692  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 34  
Hydrogen Bond Acceptor Count: 9  
Hydrogen Bond Donor Count: 2  
Rotatable Bond Count: 6  
XLogP3: 4.1  
Downstream Synthesis Route
61500-87-6    1228960-69-7 

[1]JournalofMedicinalChemistry,2012,vol.55,p.197-208

Literature fold

Title: Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905).

Journal: Journal of medicinal chemistry20120112

Title: Duffey MO, et al. Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905). J Med Chem. 2012 Jan 12;55(1):197-208.

Title: Shi JQ, et al. MLN0905, a small-molecule plk1 inhibitor, induces antitumor responses in human models of diffuse large B-cell lymphoma. Mol Cancer Ther. 2012 Sep;11(9):2045-53.

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