Title: Subepithelial trypsin induces enteric nerve-mediated anion secretion by activating proteinase-activated receptor 1 in the mouse cecum.
Journal: The journal of physiological sciences : JPS 20120501
Title: Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation.
Journal: Journal of thrombosis and haemostasis : JTH 20120301
Title: Regulation of human vascular protease-activated receptor-3 through mRNA stabilization and the transcription factor nuclear factor of activated T cells (NFAT).
Journal: Molecular pharmacology 20110801
Title: Delayed production of arachidonic acid contributes to the delay of proteinase-activated receptor-1 (PAR1)-triggered prostaglandin E2 release in rat gastric epithelial RGM1 cells.
Journal: Journal of cellular biochemistry 20110301
Title: Involvement of protein kinase C and RhoA in protease-activated receptor 1-mediated F-actin reorganization and cell growth in rat cardiomyocytes.
Journal: Journal of pharmacological sciences 20110101
Title: Thrombin and thrombin-derived peptides promote proliferation of cardiac progenitor cells in the form of cardiospheres without affecting their differentiation potential.
Journal: Journal of biological regulators and homeostatic agents 20110101
Title: Phosphatidylserine exposure and other apoptotic-like events in Bernard-Soulier syndrome platelets.
Journal: American journal of hematology 20100801
Title: Design, synthesis and biological evaluation of non-peptide PAR1 thrombin receptor antagonists based on small bifunctional templates: arginine and phenylalanine side chain groups are keys for receptor activity.
Journal: Amino acids 20100401
Title: Thrombin and trypsin directly activate vagal C-fibres in mouse lung via protease-activated receptor-1.
Journal: The Journal of physiology 20100401
Title: Opposite effects of two thiazolidinediones, ciglitazone and troglitazone, on proteinase-activated receptor-1-triggered prostaglandin E(2) release.
Journal: Toxicology 20100131
Title: Absence of proteinase-activated receptor-1 signaling in mice confers protection from fMLP-induced goblet cell metaplasia.
Journal: American journal of respiratory cell and molecular biology 20091201
Title: Bestrophin-1 encodes for the Ca2+-activated anion channel in hippocampal astrocytes.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091014
Title: Role of protease-activated receptor-1 in endothelial nitric oxide synthase-Thr495 phosphorylation.
Journal: Experimental biology and medicine (Maywood, N.J.) 20090201
Title: Activation of proteinase-activated receptors induces itch-associated response through histamine-dependent and -independent pathways in mice.
Journal: Journal of pharmacological sciences 20081101
Title: Coordinate activation of human platelet protease-activated receptor-1 and -4 in response to subnanomolar alpha-thrombin.
Journal: The Journal of biological chemistry 20081003
Title: Tissue factor induction by protease-activated receptor 1 requires intact caveolin-enriched membrane microdomains in human endothelial cells.
Journal: Journal of thrombosis and haemostasis : JTH 20071201
Title: Protease-activated receptor-induced Akt activation--regulation and possible function.
Journal: Journal of thrombosis and haemostasis : JTH 20071201
Title: Effect of PAR1 agonist on acetylcholine secretion in a newly formed neuromuscular synapse in mice.
Journal: Bulletin of experimental biology and medicine 20071101
Title: Protease-activated receptor 4-mediated Ca2+ signaling in mouse lung alveolar epithelial cells.
Journal: Life sciences 20070816
Title: Distinct Ca2+ requirement for NO production between proteinase-activated receptor 1 and 4 (PAR1 and PAR4) in vascular endothelial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20070801
Title: Protease-activated receptor-1 (PAR1) and PAR2 but not PAR4 mediate relaxations in lower esophageal sphincter.
Journal: Regulatory peptides 20070705
Title: SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts.
Journal: Basic research in cardiology 20070701
Title: Defective platelet responsiveness to thrombin and protease-activated receptors agonists in a novel case of gray platelet syndrome: correlation between the platelet defect and the alpha-granule content in the patient and four relatives.
Journal: Journal of thrombosis and haemostasis : JTH 20070301
Title: Distinct roles for PAR1- and PAR2-mediated vasomotor modulation in human arterial and venous conduits.
Journal: Journal of thrombosis and haemostasis : JTH 20070101
Title: [The role of PAR1 in the protective action of activated protein C in the non-immune mast cell activation].
Journal: Biomeditsinskaia khimiia 20070101
Title: Thrombin and PAR-1 stimulate differentiation of bone marrow-derived endothelial progenitor cells.
Journal: Journal of thrombosis and haemostasis : JTH 20060301
Title: Mechanisms for modulation of mouse gastrointestinal motility by proteinase-activated receptor (PAR)-1 and -2 in vitro.
Journal: Life sciences 20060125
Title: Two types of protease-activated receptors (PAR-1 and PAR-2) mediate calcium signaling in rat retinal ganglion cells RGC-5.
Journal: Brain research 20050621
Title: Activation of protease-activated receptor-1 triggers astrogliosis after brain injury.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050427
Title: Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.
Journal: Journal of thrombosis and haemostasis : JTH 20050401
Title: Effects of thrombin, PAR-1 activating peptide and a PAR-1 antagonist on umbilical artery resistance in vitro.
Journal: Reproductive biology and endocrinology : RB&E 20050101
Title: Proteinase-activated receptor-2-mediated relaxation in mouse tracheal and bronchial smooth muscle: signal transduction mechanisms and distinct agonist sensitivity.
Journal: The Journal of pharmacology and experimental therapeutics 20041001
Title: Distinct roles for protease-activated receptors 1 and 2 in vasomotor modulation in rat superior mesenteric artery.
Journal: Cardiovascular research 20040301
Title: Modulation of capsaicin-evoked visceral pain and referred hyperalgesia by protease-activated receptors 1 and 2.
Journal: Journal of pharmacological sciences 20040301
Title: Differential Ca2+ signaling by thrombin and protease-activated receptor-1-activating peptide in human brain microvascular endothelial cells.
Journal: American journal of physiology. Cell physiology 20040101
Title: A protective role of protease-activated receptor 1 in rat gastric mucosa.
Journal: Gastroenterology 20040101
Title: Pharmacodynamic profile of antiplatelet agents: marked differences between single versus costimulation with platelet activators.
Journal: Thrombosis research 20040101
Title: Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes.
Journal: Molecular pharmacology 20031101
Title: Bidirectional regulation of renal hemodynamics by activation of PAR1 and PAR2 in isolated perfused rat kidney.
Journal: American journal of physiology. Renal physiology 20030701
Title: Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin.
Journal: The Journal of physiology 20030615
Title: Enzymatic activation of endothelial protease-activated receptors is dependent on artery diameter in human and porcine isolated coronary arteries.
Journal: British journal of pharmacology 20020601
Title: The PAR-1-activating peptide attenuates carrageenan-induced hyperalgesia in rats.
Journal: Peptides 20020601
Title: de Garavilla L, et al. Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism. Br J Pharmacol. 2001 Aug;133(7):975-87.
Title: Kawabata A, et al. Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle.
Title: Jia Y, et al. Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620. Oncol Rep. 2015 Jun;33(6):2681-8.
