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Title: Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results.
Journal: Anticancer research 20121001
Title: Cilengitide in bevacizumab-refractory high-grade glioma: two case reports and critical review of the literature.
Journal: Anti-cancer drugs 20120801
Title: A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma.
Journal: Melanoma research 20120801
Title: Cyclic RGD peptidomimetics containing bifunctional diketopiperazine scaffolds as new potent integrin ligands.
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Title: A phase I study of continuous infusion cilengitide in patients with solid tumors.
Journal: Investigational new drugs 20120401
Title: Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium.
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Title: Peptides for cell-selective drug delivery.
Journal: Trends in pharmacological sciences 20120401
Title: Anti-angiogenic approaches to malignant gliomas.
Journal: Current cancer drug targets 20120301
Title: Cilengitide in patients with recurrent glioblastoma: the results of NABTC 03-02, a phase II trial with measures of treatment delivery.
Journal: Journal of neuro-oncology 20120101
Title: Antiangiogenic therapy for patients with recurrent and newly diagnosed malignant gliomas.
Journal: Journal of oncology 20120101
Title: Targeting the tumor microenvironment: focus on angiogenesis.
Journal: Journal of oncology 20120101
Title: Integrin-mediated cell-matrix interaction in physiological and pathological blood vessel formation.
Journal: Journal of oncology 20120101
Title: Integrin inhibitors as a therapeutic agent for ovarian cancer.
Journal: Journal of oncology 20120101
Title: Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy.
Journal: Theranostics 20120101
Title: Deciphering the Multifaceted Relationship between Oncolytic Viruses and Natural Killer Cells.
Journal: Advances in virology 20120101
Title: MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR.
Journal: Journal of translational medicine 20120101
Title: Methodology for Anti-Gene Anti-IGF-I Therapy of Malignant Tumours.
Journal: Chemotherapy research and practice 20120101
Title: RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating α(v)β₃ expression.
Journal: International journal of nanomedicine 20120101
Title: Fibronectin matrix-mediated cohesion suppresses invasion of prostate cancer cells.
Journal: BMC cancer 20120101
Title: Prostaglandins in cancer cell adhesion, migration, and invasion.
Journal: International journal of cell biology 20120101
Title: Integrins and their extracellular matrix ligands in lymphangiogenesis and lymph node metastasis.
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Title: Novel therapies in glioblastoma.
Journal: Neurology research international 20120101
Title: Current trends in targeted therapies for glioblastoma multiforme.
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Title: Vitronectin increases vascular permeability by promoting VE-cadherin internalization at cell junctions.
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Title: Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cells.
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Title: Current knowledge on pancreatic cancer.
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Title: Cilengitide treatment for malignant glioma: current status and future direction.
Journal: Neurologia medico-chirurgica 20120101
Title: Cilengitide (EMD 121974, NSC 707544) in asymptomatic metastatic castration resistant prostate cancer patients: a randomized phase II trial by the prostate cancer clinical trials consortium.
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Title: Cilengitide: a prototypic integrin inhibitor for the treatment of glioblastoma and other malignancies.
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Title: Cilengitide inhibits metastatic bone colonization in a nude rat model.
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Title: Treatment of high-grade glioma in children and adolescents.
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Title: Increasing αvβ3 selectivity of the anti-angiogenic drug cilengitide by N-methylation.
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Title: Impact of therapy on quality of life, neurocognitive function and their correlates in glioblastoma multiforme: a review.
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Title: Cilengitide induces autophagy-mediated cell death in glioma cells.
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Title: Advances in MRI assessment of gliomas and response to anti-VEGF therapy.
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Title: Radiation-induced modifications of the tumor microenvironment promote metastasis.
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Title: Pathway inhibition: emerging molecular targets for treating glioblastoma.
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Title: Phase I/II trial of cilengitide with cetuximab, cisplatin and 5-fluorouracil in recurrent and/or metastatic squamous cell cancer of the head and neck: findings of the phase I part.
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Title: Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study.
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Title: Isthmin exerts pro-survival and death-promoting effect on endothelial cells through alphavbeta5 integrin depending on its physical state.
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Title: Recurrent high-grade glioma: a diagnostic and therapeutic challenge.
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Title: Glioblastoma: changing expectations?
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Title: Cilengitide: an RGD pentapeptide ανβ3 and ανβ5 integrin inhibitor in development for glioblastoma and other malignancies.
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Title: Angiogenesis and invasion in glioma.
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Title: Vaccines targeting the neovasculature of tumors.
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Title: Integrin αvβ3-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy.
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Title: A meta-analysis of gemcitabine containing chemotherapy for locally advanced and metastatic pancreatic adenocarcinoma.
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Title: Evaluation of treatment response of cilengitide in an experimental model of breast cancer bone metastasis using dynamic PET with 18F-FDG.
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Title: Why integrin as a primary target for imaging and therapy.
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Title: Integrin targeted delivery of chemotherapeutics.
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Title: Investigation of In Vivo Targeting Kinetics of α(v)β(3)-Specific Superparamagnetic Nanoprobes by Time-Resolved MRI.
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Title: Therapeutic targets for bone metastases in breast cancer.
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Title: Bevacizumab for the treatment of recurrent glioblastoma.
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Title: Novel diagnostic and therapeutic approaches to malignant glioma.
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Title: Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.
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Title: New agents targeting angiogenesis in glioblastoma.
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Title: Molecular targets for radiation oncology in prostate cancer.
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Title: Combined modality approaches in the management of adult glioblastoma.
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Title: Anti-angiogenic therapies for children with cancer.
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Title: Cilengitide: the first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation.
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Title: Targeting integrins in malignant glioma.
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Title: Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States.
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Title: BCNU for recurrent glioblastoma multiforme: efficacy, toxicity and prognostic factors.
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Title: Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities.
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Title: Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro.
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Title: Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide.
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Title: Therapeutic application of noncytotoxic molecular targeted therapy in gliomas: growth factor receptors and angiogenesis inhibitors.
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Title: Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme.
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