Home Amines 864084-88-8
864084-88-8,MFCD09752700
Catalog No.:AA003AJC

864084-88-8 | L-Glutaminyl-L-arginyl-L-phenylalanyl-L-seryl-L-arginine

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1mg
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003AJC
Chemical Name:
L-Glutaminyl-L-arginyl-L-phenylalanyl-L-seryl-L-arginine
CAS Number:
864084-88-8
Molecular Formula:
C29H48N12O8
Molecular Weight:
692.7670
MDL Number:
MFCD09752700
SMILES:
OC[C@@H](C(=O)N[C@H](C(=O)O)CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)N)N)CCCNC(=N)N)Cc1ccccc1
Properties
Computed Properties
 
Complexity:
1170  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
49  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
12  
Rotatable Bond Count:
23  
XLogP3:
-7  

Literature

Title: Opiorphin highly improves the specific binding and affinity of MERF and MEGY to rat brain opioid receptors.

Journal: Regulatory peptides 20121010

Title: Structure-activity relationship study of opiorphin, a human dual ectopeptidase inhibitor with antinociceptive properties.

Journal: Journal of medicinal chemistry 20120209

Title: New insights into the pathophysiology of sickle cell disease-associated priapism.

Journal: The journal of sexual medicine 20120101

Title: Development and validation of a liquid chromatography-tandem mass spectrometry method for the quantification of opiorphin in human saliva.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111215

Title: Reversal of diabetic vasculopathy in a rat model of type 1 diabetes by opiorphin-related peptides.

Journal: American journal of physiology. Heart and circulatory physiology 20111001

Title: Inhibition of nociceptive responses after systemic administration of amidated kyotorphin.

Journal: British journal of pharmacology 20110701

Title: An update on analgesics.

Journal: British journal of anaesthesia 20110701

Title: On the terminal homologation of physiologically active peptides as a means of increasing stability in human serum--neurotensin, opiorphin, B27-KK10 epitope, NPY.

Journal: Chemistry & biodiversity 20110501

Title: The antidepressant-like effect of human opiorphin via opioid-dependent pathways in mice.

Journal: Neuroscience letters 20110204

Title: Human opiorphin: the lack of physiological dependence, tolerance to antinociceptive effects and abuse liability in laboratory mice.

Journal: Behavioural brain research 20101112

Title: Systemically active human opiorphin is a potent yet non-addictive analgesic without drug tolerance effects.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100801

Title: Human opiorphin is a naturally occurring antidepressant acting selectively on enkephalin-dependent delta-opioid pathways.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100601

Title: Salivary gland derived peptides as a new class of anti-inflammatory agents: review of preclinical pharmacology of C-terminal peptides of SMR1 protein.

Journal: Journal of inflammation (London, England) 20100101

Title: Experimental priapism is associated with increased oxidative stress and activation of protein degradation pathways in corporal tissue.

Journal: International journal of impotence research 20100101

Title: The mechanism of opiorphin-induced experimental priapism in rats involves activation of the polyamine synthetic pathway.

Journal: American journal of physiology. Cell physiology 20091001

Title: Effects and underlying mechanisms of human opiorphin on colonic motility and nociception in mice.

Journal: Peptides 20090701

Title: The role of opiorphins (endogenous neutral endopeptidase inhibitors) in urogenital smooth muscle biology.

Journal: The journal of sexual medicine 20090301

Title: Enkephalinase inhibitors: potential agents for the management of pain.

Journal: Current drug targets 20081001

Title: The opiorphin gene (ProL1) and its homologues function in erectile physiology.

Journal: BJU international 20080901

Title: Markers of erectile dysfunction.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20080101

Title: [Identification of human opiorphin, a natural antinociceptive modulator of opioid-dependent pathways].

Journal: Medecine sciences : M/S 20070101

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Tags:864084-88-8 Molecular Formula|864084-88-8 MDL|864084-88-8 SMILES|864084-88-8 L-Glutaminyl-L-arginyl-L-phenylalanyl-L-seryl-L-arginine