Title: Serum stability of selected decapeptide agonists of KISS1R using pseudopeptides.
Journal: Bioorganic & medicinal chemistry letters20121015
Title: Trypsin resistance of a decapeptide KISS1R agonist containing an Nω-methylarginine substitution.
Journal: Bioorganic & medicinal chemistry letters20121015
Title: Differential response of the primate HPG axis to N-methyl-D, L-aspartate, but not to Kisspeptin challenge under euglycemic and hypoglycemic conditions.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme20120601
Title: Kisspeptin-10 stimulates the release of luteinizing hormone and testosterone in pre- and post-pubertal male goats.
Journal: Animal science journal = Nihon chikusan Gakkaiho20120601
Title: Q36R polymorphism of KiSS-1 gene in Brazilian head and neck cancer patients.
Journal: Molecular biology reports20120501
Title: Kisspeptin-10 inhibits cell migration in vitro via a receptor-GSK3 beta-FAK feedback loop in HTR8SVneo cells.
Journal: Placenta20120501
Title: Association of kisspeptin-10 levels with abortus imminens: a preliminary study.
Journal: Archives of gynecology and obstetrics20120301
Title: Characterization of the kisspeptin system in human spermatozoa.
Journal: International journal of andrology20120201
Title: Developmental changes in GnRH release in response to kisspeptin agonist and antagonist in female rhesus monkeys (Macaca mulatta): implication for the mechanism of puberty.
Journal: Endocrinology20120201
Title: Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20120118
Title: Kisspeptin inhibits high-voltage activated Ca2+ channels in GnRH neurons via multiple Ca2+ influx and release pathways.
Journal: Neuroendocrinology20120101
Title: Immature rat seminal vesicles show histomorphological and ultrastructural alterations following treatment with kisspeptin-10.
Journal: Reproductive biology and endocrinology : RB&E20120101
Title: GnRH-deficient phenotypes in humans and mice with heterozygous variants in KISS1/Kiss1.
Journal: The Journal of clinical endocrinology and metabolism20111101
Title: Kisspeptin activation of supraoptic nucleus neurons in vivo.
Journal: Endocrinology20111001
Title: Effects of kisspeptin-10 on progesterone secretion in cultured chicken ovarian granulosa cells from preovulatory (F1-F3) follicles.
Journal: Peptides20111001
Title: Peripheral kisspeptin reverses short photoperiod-induced gonadal regression in Syrian hamsters by promoting GNRH release.
Journal: Reproduction (Cambridge, England)20110901
Title: Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men.
Journal: The Journal of clinical endocrinology and metabolism20110801
Title: KiSS1 mediates platinum sensitivity and metastasis suppression in head and neck squamous cell carcinoma.
Journal: Oncogene20110714
Title: Serum kisspeptin levels in Korean girls with central precocious puberty.
Journal: Journal of Korean medical science20110701
Title: Kisspeptin activates the hypothalamic-adenohypophyseal-gonadal axis in prepubertal ewe lambs.
Journal: Reproduction (Cambridge, England)20110401
Title: GPR54 is a target for suppression of metastasis in endometrial cancer.
Journal: Molecular cancer therapeutics20110401
Title: KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion.
Journal: European journal of histochemistry : EJH20110401
Title: Kisspeptin-10 elicits triphasic cytosolic calcium responses in immortalized GT1-7 GnRH neurones.
Journal: Neuroscience letters20110329
Title: Sex steroid hormones do not enhance the direct stimulatory effect of kisspetin-10 on the secretion of growth hormone from bovine anterior pituitary cells.
Journal: Animal science journal = Nihon chikusan Gakkaiho20110201
Title: Intraperitoneal kisspeptin-10 administration induces dose-dependent degenerative changes in maturing rat testes.
Journal: Life sciences20110131
Title: Kisspeptin-evoked calcium signals in isolated primary rat gonadotropin- releasing hormone neurones.
Journal: Neuroendocrinology20110101
Title: Study on the effect of peripheral kisspeptin administration on basal and glucose-induced insulin secretion under fed and fasting conditions in the adult male rhesus monkey (Macaca mulatta).
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme20110101
Title: The vasoactive potential of kisspeptin-10 in the peripheral vasculature.
Journal: PloS one20110101
Title: GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness.
Journal: PloS one20110101
Title: Kisspeptins: bridging energy homeostasis and reproduction.
Journal: Brain research20101210
Title: Plasma levels of kisspeptins in postmenopausal Chinese women do not show substantial elevation.
Journal: Peptides20101201
Title: Evaluating DNA methylation and gene expression variability in the human term placenta.
Journal: Placenta20101201
Title: Twice-weekly administration of kisspeptin-54 for 8 weeks stimulates release of reproductive hormones in women with hypothalamic amenorrhea.
Journal: Clinical pharmacology and therapeutics20101201
Title: Human kisspeptins activate neuropeptide FF2 receptor.
Journal: Neuroscience20100929
Title: The role of sexual steroid hormones in the direct stimulation by Kisspeptin-10 of the secretion of luteinizing hormone, follicle-stimulating hormone and prolactin from bovine anterior pituitary cells.
Journal: Animal reproduction science20100901
Title: beta-Sheet aggregation of kisspeptin-10 is stimulated by heparin but inhibited by amphiphiles.
Journal: Biopolymers20100801
Title: KISS1 is down-regulated by 17beta-estradiol in MDA-MB-231 cells through a nonclassical mechanism and loss of ribonucleic acid polymerase II binding at the proximal promoter.
Journal: Endocrinology20100801
Title: Acute inflammation reduces kisspeptin immunoreactivity at the arcuate nucleus and decreases responsiveness to kisspeptin independently of its anorectic effects.
Journal: American journal of physiology. Endocrinology and metabolism20100701
Title: Kisspeptin regulates prolactin release through hypothalamic dopaminergic neurons.
Journal: Endocrinology20100701
Title: Gonadal and nongonadal regulation of sex differences in hypothalamic Kiss1 neurones.
Journal: Journal of neuroendocrinology20100701
Title: Kisspeptin is released from human prostate cancer cell lines but plasma kisspeptin is not elevated in patients with prostate cancer.
Journal: Oncology reports20100601
Title: Direct and indirect effects of kisspeptin on liver oxidant and antioxidant systems in young male rats.
Journal: Cell biochemistry and function20100601
Title: Presence of kisspeptin-like immunoreactivity in human adrenal glands and adrenal tumors.
Journal: Journal of molecular neuroscience : MN20100501
Title: Insights into the mechanism by which kisspeptin stimulates a preovulatory LH surge and ovulation in seasonally acyclic ewes: potential role of estradiol.
Journal: Domestic animal endocrinology20100501
Title: Mutations of the KISS1 gene in disorders of puberty.
Journal: The Journal of clinical endocrinology and metabolism20100501
Title: Kisspeptin/GPR54 system as potential target for endocrine disruption of reproductive development and function.
Journal: International journal of andrology20100401
Title: Differential regulation of kiss1 expression by melatonin and gonadal hormones in male and female Syrian hamsters.
Journal: Journal of biological rhythms20100401
Title: Increased plasma metastin levels in adolescent women with polycystic ovary syndrome.
Journal: European journal of obstetrics, gynecology, and reproductive biology20100301
Title: A kisspeptin-10 analog with greater in vivo bioactivity than kisspeptin-10.
Journal: American journal of physiology. Endocrinology and metabolism20100201
Title: Central administration of kisspeptin-10 inhibits natriuresis and diuresis induced by blood volume expansion in anesthetized male rats.
Journal: Acta pharmacologica Sinica20100201
Title: The kisspeptin/neurokinin B/dynorphin (KNDy) cell population of the arcuate nucleus: sex differences and effects of prenatal testosterone in sheep.
Journal: Endocrinology20100101
Title: A twisted kiss: in vitro and in vivo evidence of genetic variation and suppressed transcription of the metastasis-suppressor gene KiSS1 in early breast cancer.
Journal: Neoplasma20100101
Title: Hypothesis: kisspeptin mediates male hypogonadism in obesity and type 2 diabetes.
Journal: Neuroendocrinology20100101
Title: Central administration of kisspeptin-10 inhibits water and sodium excretion of anesthetized male rats and the involvement of arginine vasopressin.
Journal: Endocrine research20100101
Title: Assessment of constitutive activity and internalization of GPR54 (KISS1-R).
Journal: Methods in enzymology20100101
Title: Kisspeptin increases GnRH mRNA expression and secretion in GnRH secreting neuronal cell lines.
Journal: Molecular and cellular endocrinology20091113
Title: Subcutaneous injection of kisspeptin-54 acutely stimulates gonadotropin secretion in women with hypothalamic amenorrhea, but chronic administration causes tachyphylaxis.
Journal: The Journal of clinical endocrinology and metabolism20091101
Title: Studies of the localisation of kisspeptin within the pituitary of the rhesus monkey (Macaca mulatta) and the effect of kisspeptin on the release of non-gonadotropic pituitary hormones.
Journal: Journal of neuroendocrinology20091001
Title: Kisspeptin signaling in the brain.
Journal: Endocrine reviews20091001
Title: KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis.
Journal: Molecular pharmacology20090501
Title: Kisspeptin offers a novel therapeutic target in reproduction.
Journal: Current opinion in investigational drugs (London, England : 2000)20090401
Title: Kisspeptin-10 facilitates a plasma membrane-driven calcium oscillator in gonadotropin-releasing hormone-1 neurons.
Journal: Endocrinology20090301
Title: KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction.
Journal: American journal of physiology. Endocrinology and metabolism20090301
Title: Oestrogen, kisspeptin, GPR54 and the pre-ovulatory luteinising hormone surge.
Journal: Journal of neuroendocrinology20090301
Title: Editorial comment on: Metastin inhibits migration and invasion of renal cell carcinoma with overexpression of metastin receptor.
Journal: European urology20090201
Title: Comparison of the effects of peripherally administered kisspeptins.
Journal: Regulatory peptides20090108
Title: The role of kisspeptin and GPR54 in the hippocampus.
Journal: Peptides20090101
Title: Prognostic value of metastin expression in human pancreatic cancer.
Journal: Journal of experimental & clinical cancer research : CR20090101
Title: Nuclear magnetic resonance and circular dichroism study of metastin (Kisspeptin-54) structure in solution.
Journal: Clinical & experimental metastasis20090101
Title: Placenta-derived fetal specific mRNA is more readily detectable in maternal plasma than in whole blood.
Journal: PloS one20090101
Title: Seasonal and cyclical change in the luteinizing hormone response to kisspeptin in the ewe.
Journal: Neuroendocrinology20090101
Title: Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat.
Journal: PloS one20090101
Title: Short-term fasting attenuates the response of the HPG axis to kisspeptin challenge in the adult male rhesus monkey (Macaca mulatta).
Journal: Life sciences20081107
Title: Systemic dissemination in cancer of unknown primary is independent of mutational inactivation of the KiSS-1 metastasis-suppressor gene.
Journal: Pathology oncology research : POR20080901
Title: Dysregulated human renin expression in transgenic mice carrying truncated genomic constructs: evidence supporting the presence of insulators at the renin locus.
Journal: American journal of physiology. Renal physiology20080901
Title: Sex steroids and leptin regulate the 'first Kiss' (KiSS 1/G-protein-coupled receptor 54 system) in human gonadotropin-releasing-hormone-secreting neuroblasts.
Journal: The journal of sexual medicine20080501
Title: Exogenous kisspeptin does not alter photoperiod-induced gonadal regression in Siberian hamsters (Phodopus sungorus).
Journal: General and comparative endocrinology20080501
Title: Kisspeptin depolarizes gonadotropin-releasing hormone neurons through activation of TRPC-like cationic channels.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20080423
Title: Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol.
Journal: Endocrinology20080401
Title: Opposite roles of estrogen receptor (ER)-alpha and ERbeta in the modulation of luteinizing hormone responses to kisspeptin in the female rat: implications for the generation of the preovulatory surge.
Journal: Endocrinology20080401
Title: Effects of kisspeptin-10 on the electrophysiological manifestation of gonadotropin-releasing hormone pulse generator activity in the female rat.
Journal: Endocrinology20080301
Title: A GPR54-activating mutation in a patient with central precocious puberty.
Journal: The New England journal of medicine20080214
Title: The role of kisspeptins and GPR54 in the neuroendocrine regulation of reproduction.
Journal: Annual review of physiology20080101
Title: GPR54 and kisspeptins.
Journal: Results and problems in cell differentiation20080101
Title: Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets.
Journal: BMC cancer20080101
Title: Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer.
Journal: Breast cancer research : BCR20080101
Title: Interaction of estrogen and progesterone on kisspeptin-10-stimulated luteinizing hormone and growth hormone in ovariectomized cows.
Journal: Neuroendocrinology20080101
Title: Metastin stimulates aldosterone synthesis in human adrenal cells.
Journal: Reproductive sciences (Thousand Oaks, Calif.)20071201
Title: Kisspeptin synchronizes preovulatory surges in cyclical ewes and causes ovulation in seasonally acyclic ewes.
Journal: Endocrinology20071101
Title: Estrogen regulates KiSS1 gene expression through estrogen receptor alpha and SP protein complexes.
Journal: Endocrinology20071001
Title: High tumoral levels of Kiss1 and G-protein-coupled receptor 54 expression are correlated with poor prognosis of estrogen receptor-positive breast tumors.
Journal: Endocrine-related cancer20070901
Title: The kisspeptin receptor GPR54 is required for sexual differentiation of the brain and behavior.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20070815
Title: Effect of continuous intravenous administration of human metastin 45-54 on the neuroendocrine activity of the hypothalamic-pituitary-testicular axis in the adult male rhesus monkey (Macaca mulatta).
Journal: Endocrinology20070701
Title: Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys.
Journal: The Journal of clinical endocrinology and metabolism20070701
Title: Expression of metastin and a G-protein-coupled receptor (AXOR12) in epithelial ovarian cancer.
Journal: European journal of cancer (Oxford, England : 1990)20070601
Title: The neuroendocrine physiology of kisspeptin in the human.
Journal: Reviews in endocrine & metabolic disorders20070301
Title: Kisspeptin: a key link to seasonal breeding.
Journal: Reviews in endocrine & metabolic disorders20070301
Title: Metastin (KiSS-1) mimetics identified from peptide structure-activity relationship-derived pharmacophores and directed small molecule database screening.
Journal: Journal of medicinal chemistry20070208
Title: Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma.
Journal: BMC medicine20070101
Title: Pediatric plenary session. Introduction. Puberty.
Journal: Hormone research20070101
Title: Driving reproduction: RFamide peptides behind the wheel.
Journal: Hormones and behavior20061201
Title: Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats.
Journal: American journal of physiology. Endocrinology and metabolism20061101
Title: The role of KiSS-1 in the regulation of puberty in higher primates.
Journal: European journal of endocrinology20061101
Title: Kisspeptin mediates the photoperiodic control of reproduction in hamsters.
Journal: Current biology : CB20060905
Title: A role for kisspeptin in islet function.
Journal: Diabetologia20060901
Title: Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats.
Journal: Diabetes20060901
Title: Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha.
Journal: Neuroscience letters20060703
Title: Hypothalamic expression of KiSS-1 system and gonadotropin-releasing effects of kisspeptin in different reproductive states of the female Rat.
Journal: Endocrinology20060601
Title: Plasma metastin levels are negatively correlated with insulin resistance and free androgens in women with polycystic ovary syndrome.
Journal: Fertility and sterility20060601
Title: Parathyroid hormone-related protein regulates tumor-relevant genes in breast cancer cells.
Journal: The Journal of biological chemistry20060526
Title: Continuous human metastin 45-54 infusion desensitizes G protein-coupled receptor 54-induced gonadotropin-releasing hormone release monitored indirectly in the juvenile male Rhesus monkey (Macaca mulatta): a finding with therapeutic implications.
Journal: Endocrinology20060501
Title: Administration of kisspeptin-54 into discrete regions of the hypothalamus potently increases plasma luteinising hormone and testosterone in male adult rats.
Journal: Journal of neuroendocrinology20060501
Title: Minireview: kisspeptin neurons as central processors in the regulation of gonadotropin-releasing hormone secretion.
Journal: Endocrinology20060301
Title: Minireview: the neuroendocrine regulation of puberty: is the time ripe for a systems biology approach?
Journal: Endocrinology20060301
Title: Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity.
Journal: Bioorganic & medicinal chemistry letters20060101
Title: KiSS-1: a likely candidate for the photoperiodic control of reproduction in seasonal breeders.
Journal: Chronobiology international20060101
Title: Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males.
Journal: The Journal of clinical endocrinology and metabolism20051201
Title: Cancer metastasis-suppressing peptide metastin upregulates excitatory synaptic transmission in hippocampal dentate granule cells.
Journal: Journal of neurophysiology20051101
Title: KiSS-1/G protein-coupled receptor 54 metastasis suppressor pathway increases myocyte-enriched calcineurin interacting protein 1 expression and chronically inhibits calcineurin activity.
Journal: The Journal of clinical endocrinology and metabolism20050901
Title: Discovery of novel regulatory peptides by reverse pharmacology: spotlight on chemerin and the RF-amide peptides metastin and QRFP.
Journal: Current protein & peptide science20050601
Title: KiSS1 suppresses metastasis in human ovarian cancer via inhibition of protein kinase C alpha.
Journal: Clinical & experimental metastasis20050101
Title: Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis.
Journal: Journal of neuroendocrinology20041001
Title: In vivo and in situ modulation of the expression of genes involved in metastasis and angiogenesis in a patient treated with topical imiquimod for melanoma skin metastases.
Journal: The British journal of dermatology20040401
Title: Differential expression of the closely linked KISS1, REN, and FLJ10761 genes in transgenic mice.
Journal: Physiological genomics20040312
Title: Large transgenes reveal their secrets. Focus on 'differential expression of the closely linked KISS1, REN, and FLJ10761 genes in transgenic mice'.
Journal: Physiological genomics20040312
Title: Clinical significance of the loss of KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in esophageal squamous cell carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20040215
Title: Quantitative reverse transcriptase polymerase chain reaction analysis for KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in hepatocellular carcinoma.
Journal: Journal of cancer research and clinical oncology20030901
Title: The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54.
Journal: The Journal of biological chemistry20010914
Title: Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor.
Journal: Nature20010531
Title: KiSS-1 represses 92-kDa type IV collagenase expression by down-regulating NF-kappa B binding to the promoter as a consequence of Ikappa Balpha -induced block of p65/p50 nuclear translocation.
Journal: The Journal of biological chemistry20010112
Title: Regulation of GPR54 signaling by GRK2 and {beta}-arrestin.
Journal: Molecular endocrinology (Baltimore, Md.)
Title: Son HE, et al. Kisspeptin-10 (KP-10) stimulates osteoblast differentiation through GPR54-mediated regulation of BMP2 expression and activation. Sci Rep. 2018 Feb 1;8(1):2134.
