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76932-56-4,MFCD00871253
Catalog No.:AA0038ZS

76932-56-4 | Luteinizing hormone-releasing factor (swine), 6-[3-(2-naphthalenyl)-D-alanine]-

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1mg
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$132.00   $93.00
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10mg
95
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50mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0038ZS
Chemical Name:
Luteinizing hormone-releasing factor (swine), 6-[3-(2-naphthalenyl)-D-alanine]-
CAS Number:
76932-56-4
Molecular Formula:
C66H83N17O13
Molecular Weight:
1322.4713
MDL Number:
MFCD00871253
SMILES:
OC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)CCCNC(=N)N)CC(C)C)Cc1ccc2c(c1)cccc2)Cc1ccc(cc1)O)NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@@H]1CCC(=O)N1)Cc1nc[nH]c1
Properties
Computed Properties
 
Complexity:
2730  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
96  
Hydrogen Bond Acceptor Count:
15  
Hydrogen Bond Donor Count:
16  
Rotatable Bond Count:
33  
XLogP3:
0.8  

Literature

Title: Development of semen quality following reversible downregulation of testicular function in male dogs with a GnRH agonist implant.

Journal: Reproduction in domestic animals = Zuchthygiene 20120801

Title: Elevated progesterone in GnRH agonist down regulated in vitro fertilisation (IVFICSI) cycles reduces live birth rates but not embryo quality.

Journal: Archives of gynecology and obstetrics 20120201

Title: A case of progesterone-induced anaphylaxis, cyclic urticaria/angioedema, and autoimmune dermatitis.

Journal: Journal of women's health (2002) 20110401

Title: Sterile abscess formation in response to two separate branded long-acting gonadotropin-releasing hormone agonists.

Journal: Clinical therapeutics 20100901

Title: A randomised controlled trial of 300 versus 225 IU recombinant FSH for ovarian stimulation in predicted normal responders by antral follicle count.

Journal: BJOG : an international journal of obstetrics and gynaecology 20100601

Title: Evaluation of the clinical efficacy of Gonazon implants in the treatment of reproductive pathologies, behavioral problems, and suppression of reproductive function in the male dog.

Journal: Theriogenology 20100415

Title: Successful pregnancy after gonadotropin-releasing hormone analogue and hysteroscopic myomectomy in a woman with diffuse uterine leiomyomatosis.

Journal: Archives of gynecology and obstetrics 20090701

Title: Controlled delivery of a GnRH agonist by a silastic implant (Gonazon) results in long-term contraception in queens.

Journal: Reproduction in domestic animals = Zuchthygiene 20090701

Title: Recrudescence of spermatogenesis in the dog following downregulation using a slow release GnRH agonist implant.

Journal: Reproduction in domestic animals = Zuchthygiene 20090701

Title: Reversible downregulation of endocrine and germinative testicular function (hormonal castration) in the dog with the GnRH-agonist azagly-nafarelin as a removable implant 'Gonazon'; a preclinical trial.

Journal: Theriogenology 20090415

Title: Prospective randomised trial comparing gonadotrophin-releasing hormone analogues with triple tourniquets at open myomectomy.

Journal: BJOG : an international journal of obstetrics and gynaecology 20090401

Title: Consensus statement on the use of gonadotropin-releasing hormone analogs in children.

Journal: Pediatrics 20090401

Title: [Application of Pfizer drugs in the obstetrics and gynecology practice].

Journal: Akusherstvo i ginekologiia 20090101

Title: Endometriosis can evade diagnosis.

Journal: RN 20080901

Title: Teriparatide (recombinant human parathyroid hormone 1-34) in postmenopausal women with osteoporosis: systematic review.

Journal: Sao Paulo medical journal = Revista paulista de medicina 20080901

Title: [Some possibilities for application of 'Pfizer' medicines--Prostin 15m, Prostin E2, Prepidil gel, Dostinex, Synarel--in the obstetrician practice].

Journal: Akusherstvo i ginekologiia 20070101

Title: Treatment with a subcutaneous GnRH agonist containing controlled release device reversibly prevents puberty in bitches.

Journal: Theriogenology 20061001

Title: A relative reduction in mid-follicular LH concentrations during GnRH agonist IVF/ICSI cycles leads to lower live birth rates.

Journal: Human reproduction (Oxford, England) 20061001

Title: [Endometriosis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060401

Title: [In vitro fertilization and embryo transfer].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060401

Title: A comparative randomized trial to assess the impact of oral contraceptive pretreatment on follicular growth and hormone profiles in GnRH antagonist-treated patients.

Journal: Human reproduction (Oxford, England) 20060101

Title: Luteal phase characteristics following GnRH antagonist or agonist treatment - a comparative study.

Journal: Reproductive biomedicine online 20060101

Title: Danazol treatment of endometriosis-associated pain.

Journal: Journal of minimally invasive gynecology 20060101

Title: GnRH analogs: options for endometriosis-associated pain treatment.

Journal: Journal of minimally invasive gynecology 20060101

Title: Autoimmune progesterone dermatitis: a rare pathology.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20051101

Title: A randomized, parallel, comparative study of the efficacy and safety of nafarelin versus danazol in the treatment of endometriosis in Taiwan.

Journal: Journal of the Chinese Medical Association : JCMA 20050701

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Association of bone mineral density with vitamin D and estrogen receptor gene polymorphisms during GnRH agonist treatment.

Journal: The journal of obstetrics and gynaecology research 20040401

Title: Serum levels of prostate-specific antigen and androgens after nasal administration of a gonadotropin releasing hormone-agonist in hirsute women.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040401

Title: Delivery and stability of LHRH and Nafarelin in human skin: the effect of constant/pulsed iontophoresis.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040201

Title: Dose of GnRH agonist (nafarelin acetate) affects intrafollicular PAPP-A expression in controlled ovarian hyperstimulation cycle.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20040115

Title: Endometrial response to IVF hormonal manipulation: comparative analysis of menopausal, down regulated and natural cycles.

Journal: Reproductive biology and endocrinology : RB&E 20040101

Title: Endometriosis and its treatment with danazol or lupron in relation to ovarian cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031101

Title: [Effect of homocysteine concentration in follicular fluid on a degree of oocyte maturity].

Journal: Ginekologia polska 20031001

Title: Cytogenetic analysis of uterine leiomyoma: the size, histopathology and GnRHa-response in relation to chromosome karyotype.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20030910

Title: Chronic treatment with an agonist of gonadotropin-releasing hormone enhances luteal function in cattle.

Journal: Biology of reproduction 20030801

Title: Membrane activity of biotechnological peptide drugs.

Journal: Chemical communications (Cambridge, England) 20030621

Title: The administration of the GnRH antagonist, cetrorelix, to ooctye donors simplifies oocyte donation.

Journal: Human reproduction (Oxford, England) 20030601

Title: Effect of chronic treatment with the gonadotrophin-releasing hormone agonist azagly-nafarelin on basal concentrations of LH in prepubertal bulls.

Journal: Reproduction (Cambridge, England) 20030201

Title: The serum concentration of estradiol after embryo transfer and the decline from preovulatory levels may influence the success of IVF treatment.

Journal: Hormone research 20030101

Title: In-vivo ovarian androgen responses to recombinant FSH with and without recombinant LH in polycystic ovarian syndrome.

Journal: Human reproduction (Oxford, England) 20021001

Title: Clinical evaluation of three different gonadotrophin-releasing hormone analogues in an IVF programme: a prospective study.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20020710

Title: Impact of six months of GnRH agonist therapy for endometriosis. Is there an age-related effect on bone mineral density?

Journal: The Journal of reproductive medicine 20020701

Title: [Comparative study of the efficiency of gonadotrope releasing hormone (GnRH) analogs for the treatment of endometriosis].

Journal: Orvosi hetilap 20020616

Title: Body fat distribution, insulin sensitivity, ovarian dysfunction and serum lipoproteins in patients with polycystic ovary syndrome.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20020201

Title: The case of the elusive androgen.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20020101

Title: Acute exacerbation of chronic maxillary sinusitis during therapy with nafarelin nasal spray.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20011201

Title: Prospective randomized comparison of ovarian blockade with nafarelin versus leuprolide during ovarian stimulation with recombinant FSH in an ICSI program.

Journal: Journal of assisted reproduction and genetics 20011101

Title: A prospective randomized comparison of routine buserelin acetate and a decreasing dosage of nafarelin acetate with a low-dose gonadotropin-releasing hormone agonist protocol for in vitro fertilization and intracytoplasmic sperm injection.

Journal: Fertility and sterility 20010901

Title: Utero-ovarian blood flow characteristics of pituitary desensitization.

Journal: Human reproduction (Oxford, England) 20010801

Title: Changes in quality of life after hormonal treatment of endometriosis.

Journal: Acta obstetricia et gynecologica Scandinavica 20010701

Title: Ovarian hyperstimulation after the sole use of a gonadotrophin-releasing hormone agonist (Nafarelin) as a complication of in vitro fertilisation treatment.

Journal: Journal of assisted reproduction and genetics 20010601

Title: [Nafarelin acetate (Synarel) and thermocoagulation in the treatment of endometriosis].

Journal: Ginekologia polska 20010501

Title: Medical and surgical therapies for pain associated with endometriosis.

Journal: Journal of women's health & gender-based medicine 20010301

Title: [Comparison of different protocols of ovulation induction, by GnRH agonists and chorionic gonadotropin].

Journal: Gynecologie, obstetrique & fertilite 20010201

Title: Efficacy of nafarelin in assisted reproductive technology: a meta-analysis.

Journal: Human reproduction update 20010101

Title: Hormonal therapy for the subfertility of cryptorchidism.

Journal: Hormone research 20010101

Title: Revisiting gonadotrophin-releasing hormone agonist protocols and management of poor ovarian responses to gonadotrophins.

Journal: Human reproduction update 19980101

Title: Uses of GnRH agonists.

Journal: Journal of obstetric, gynecologic, and neonatal nursing : JOGNN 19940901

Title: Nafarelin in the management of endometriosis: quality of life assessment.

Journal: American journal of obstetrics and gynecology 19920201

Title: Gonadotropin-releasing hormone analogs: update on new findings.

Journal: American journal of obstetrics and gynecology 19920201

Title: Pharmacologic management of endometriosis.

Journal: Clinical pharmacy 19910701

Title: Nafarelin acetate: a gonadotropin-releasing hormone agonist for the treatment of endometriosis.

Journal: DICP : the annals of pharmacotherapy 19901201

Title: Nafarelin. A review of its pharmacodynamic and pharmacokinetic properties, and clinical potential in sex hormone-related conditions.

Journal: Drugs 19900401

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Tags:76932-56-4 Molecular Formula|76932-56-4 MDL|76932-56-4 SMILES|76932-56-4 Luteinizing hormone-releasing factor (swine), 6-[3-(2-naphthalenyl)-D-alanine]-