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475-81-0,MFCD00075953
Catalog No.:AA00DA24

475-81-0 | BOLDINE DIMETHYL ETHER

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1mg
≥95%
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$48.00   $33.00
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5mg
≥95%
in stock  
$172.00   $120.00
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10mg
≥95%
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$252.00   $176.00
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50mg
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$566.00   $396.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DA24
Chemical Name:
BOLDINE DIMETHYL ETHER
CAS Number:
475-81-0
Molecular Formula:
C21H25NO4
Molecular Weight:
355.4275
MDL Number:
MFCD00075953
SMILES:
COc1cc2c(cc1OC)C[C@H]1c3c2c(OC)c(OC)cc3CCN1C
NSC Number:
34396
Properties
Computed Properties
 
Complexity:
489  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
4  
XLogP3:
3.4  

Literature

Title: Michaelis-Menten kinetic analysis of drugs of abuse to estimate their affinity to human P-glycoprotein.

Journal: Toxicology letters 20130227

Title: High-performance liquid chromatography-time-of-flight mass spectrometry with adjustment of fragmentor voltages for rapid identification of alkaloids in rat plasma after oral administration of rhizoma Corydalis extracts.

Journal: Journal of separation science 20120701

Title: Effect of cosmetic ingredients as anticellulite agents: synergistic action of actives with in vitro and in vivo efficacy.

Journal: Journal of cosmetic dermatology 20120301

Title: [Chemical constituents from Corydalis yanhusuo].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120101

Title: Preparative isolation of alkaloids from Dactylicapnos scandens using pH-zone-refining counter-current chromatography by changing the length of the separation column.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111201

Title: Alkaloids from Glaucium flavum from Sardinia.

Journal: Natural product research 20100701

Title: Screening of antinociceptive components in Corydalis yanhusuo W.T. Wang by comprehensive two-dimensional liquid chromatography/tandem mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20100301

Title: The antinociceptive and anti-inflammatory activities of caulerpin, a bisindole alkaloid isolated from seaweeds of the genus Caulerpa.

Journal: Marine drugs 20091201

Title: Ascorbic acid and tetrahydrobiopterin potentiate the EDHF phenomenon by generating hydrogen peroxide.

Journal: Cardiovascular research 20091101

Title: Toll-like receptor-mediated anti-inflammatory action of glaucine and oxoglaucine.

Journal: Fitoterapia 20091001

Title: Amino acid derivatives of aporphinic alkaloid glaucine and their antioxidant activity.

Journal: Advances in experimental medicine and biology 20090101

Title: Cardiovascular toxicity associated with recreational use of diphenylprolinol (diphenyl-2-pyrrolidinemethanol [D2PM]).

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20080901

Title: Cinnamoyl- and hydroxycinnamoyl amides of glaucine and their antioxidative and antiviral activities.

Journal: Bioorganic & medicinal chemistry 20080801

Title: Detection of the pharmaceutical agent glaucine as a recreational drug.

Journal: European journal of clinical pharmacology 20080501

Title: Advances in development of dopaminergic aporphinoids.

Journal: Journal of medicinal chemistry 20070125

Title: Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr.

Journal: Bioorganic & medicinal chemistry 20070115

Title: Antihyperglycemic effect of aporphines and their derivatives in normal and diabetic rats.

Journal: Planta medica 20061001

Title: [Acute glaucine syndrome in the physician's practice: the clinical picture and potential danger].

Journal: Klinicheskaia meditsina 20060101

Title: Photostability and photoprotection factor of boldine and glaucine.

Journal: Journal of photochemistry and photobiology. B, Biology 20050701

Title: Structure-affinity relationships of halogenated predicentrine and glaucine derivatives at D1 and D2 dopaminergic receptors: halogenation and D1 receptor selectivity.

Journal: Bioorganic & medicinal chemistry 20050601

Title: A novel alkaloid from Mitrephora maingayi.

Journal: Natural product research 20050601

Title: Photochemistry of phytoalexins containing phenalenone-like chromophores: photophysics and singlet oxygen photosensitizing properties of the plant oxoaporphine alkaloid oxoglaucine.

Journal: Photochemistry and photobiology 20050101

Title: Identification and quantification of isoquinoline alkaloids in the genus Sarcocapnos by GC-MS.

Journal: Phytochemical analysis : PCA 20050101

Title: The efficient synthesis of morphinandienone alkaloids by using a combination of hypervalent iodine(III) reagent and heteropoly acid.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20041011

Title: Alkaloids from Cassytha filiformis and related aporphines: antitrypanosomal activity, cytotoxicity, and interaction with DNA and topoisomerases.

Journal: Planta medica 20040501

Title: [Resource investigation and quality evaluation on wild Corydalis yanhusuo].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040501

Title: Antifungal activity of the methanolic extract and alkaloids of Glaucium oxylobum.

Journal: Fitoterapia 20030701

Title: Effects of some antioxidative aporphine derivatives on striatal dopaminergic transmission and on MPTP-induced striatal dopamine depletion in B6CBA mice.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030201

Title: Behavioural evidence of agonist-like effect of isoteoline at 5-HT1B serotonergic receptors in mice.

Journal: The Journal of pharmacy and pharmacology 20030101

Title: Geographic distribution of three alkaloid chemotypes of Croton lechleri.

Journal: Journal of natural products 20020601

Title: Seasonal variation of the chemical constituents from Croton species.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101

Title: Antipoliovirus structure-activity relationships of some aporphine alkaloids.

Journal: Journal of natural products 19980401

Title: Central action of glaucine in rodents.

Journal: Acta poloniae pharmaceutica 19940101

Title: Objective evaluation of dextromethorphan and glaucine as antitussive agents.

Journal: British journal of clinical pharmacology 19840501

Title: J Cortijo, et al. Bronchodilator and Anti-Inflammatory Activities of Glaucine: In Vitro Studies in Human Airway Smooth Muscle and Polymorphonuclear Leukocytes. Br J Pharmacol. 1999 Aug;127(7):1641-51.

Title: Golo M J Meyer, et al. Studies on the in Vivo Contribution of Human Cytochrome P450s to the Hepatic Metabolism of Glaucine, a New Drug of Abuse. Biochem Pharmacol. 2013 Nov 15;86(10):1497-506.

Title: Maya Spasova, et al. Cinnamoyl- And Hydroxycinnamoyl Amides of Glaucine and Their Antioxidative and Antiviral Activities. Bioorg Med Chem. 2008 Aug 1;16(15):7457-61.

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