Title: Boldine enhances bile production in rats via osmotic and farnesoid X receptor dependent mechanisms.
Journal: Toxicology and applied pharmacology 20150515
Title: Boldine, a natural aporphine alkaloid, inhibits telomerase at non-toxic concentrations.
Journal: Chemico-biological interactions 20150425
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Applied biological and physicochemical activity of isoquinoline alkaloids: oxoisoaporphine and boldine.
Journal: Molecules (Basel, Switzerland) 20120912
Title: Acetylcholinesterase inhibition, antioxidant activity and toxicity of Peumus boldus water extracts on HeLa and Caco-2 cell lines.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801
Title: Anti-acetylcholinesterase, anti-α-glucosidase, anti-leishmanial and anti-fungal activities of chemical constituents of Beilschmiedia species.
Journal: Fitoterapia 20120301
Title: The aporphine alkaloid boldine improves endothelial function in spontaneously hypertensive rats.
Journal: Experimental biology and medicine (Maywood, N.J.) 20120101
Title: Comparison of oxidant/antioxidant, detoxification systems in various tissue homogenates and mitochondria of rats with diabetes induced by streptozocin.
Journal: Experimental diabetes research 20120101
Title: An overview of the evidence and mechanisms of herb-drug interactions.
Journal: Frontiers in pharmacology 20120101
Title: Boldo prevents UV light and nitric oxide-mediated plasmid DNA damage and reduces the expression of Hsp70 protein in melanoma cancer cells.
Journal: The Journal of pharmacy and pharmacology 20110901
Title: In vitro cytotoxic evaluation of a novel phosphinyl derivative of boldine.
Journal: Molecules (Basel, Switzerland) 20110307
Title: New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae.
Journal: The Journal of biological chemistry 20110225
Title: Protective Mechanism of KIOM-4 in Streptozotocin-Induced Pancreatic β-Cells Damage Is Involved in the Inhibition of Endoplasmic Reticulum Stress.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Assessment of antiproliferative and antiplasmodial activities of five selected Apocynaceae species.
Journal: BMC complementary and alternative medicine 20110101
Title: Comparison of antioxidant effects of honey, glibenclamide, metformin, and their combinations in the kidneys of streptozotocin-induced diabetic rats.
Journal: International journal of molecular sciences 20110101
Title: Nanogram-scale preparation and NMR analysis for mass-limited small volatile compounds.
Journal: PloS one 20110101
Title: A novel structural framework for α(1A/D)-adrenoceptor selective antagonists identified using subtype selective pharmacophores.
Journal: PloS one 20110101
Title: Antiproliferative and phytochemical analyses of leaf extracts of ten Apocynaceae species.
Journal: Pharmacognosy research 20110101
Title: KIOM-4 Protects against Oxidative Stress-Induced Mitochondrial Damage in Pancreatic β-cells via Its Antioxidant Effects.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Inhibition of experimental myopia by a dopamine agonist: different effectiveness between form deprivation and hyperopic defocus in guinea pigs.
Journal: Molecular vision 20110101
Title: Modeling natural anti-inflammatory compounds by molecular topology.
Journal: International journal of molecular sciences 20110101
Title: Protective effects of aqueous and ethanolic extracts of Nigella sativa L. and Portulaca oleracea L. on free radical induced hemolysis of RBCs.
Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101
Title: Quantitative analysis of boldine alkaloid in natural extracts by cyclic voltammetry at a liquid-liquid interface and validation of the method by comparison with high performance liquid chromatography.
Journal: Talanta 20101215
Title: Cytotoxic thiocarbamate derivatives of boldine.
Journal: Natural product communications 20101001
Title: Direct identification of phenolic constituents in Boldo Folium (Peumus boldus Mol.) infusions by high-performance liquid chromatography with diode array detection and electrospray ionization tandem mass spectrometry.
Journal: Journal of chromatography. A 20100122
Title: Anti-photoaging and photoprotective compounds derived from marine organisms.
Journal: Marine drugs 20100101
Title: Current and developing therapeutic agents in the treatment of Chagas disease.
Journal: Drug design, development and therapy 20100101
Title: Boldine: a potential new antiproliferative drug against glioma cell lines.
Journal: Investigational new drugs 20091201
Title: The hunt for natural skin whitening agents.
Journal: International journal of molecular sciences 20091201
Title: Ascorbic acid and tetrahydrobiopterin potentiate the EDHF phenomenon by generating hydrogen peroxide.
Journal: Cardiovascular research 20091101
Title: The aporphine alkaloid boldine induces adiponectin expression and regulation in 3T3-L1 cells.
Journal: Journal of medicinal food 20091001
Title: Effect of boldo (Peumus boldus Molina) infusion on lipoperoxidation induced by cisplatin in mice liver.
Journal: Phytotherapy research : PTR 20090701
Title: Grandine A, a new proaporphine alkaloid from the bark of Phoebe grandis.
Journal: Molecules (Basel, Switzerland) 20090323
Title: 5-Hydroxytryptamine2A receptor binding activity of compounds from Litsea sessilis.
Journal: Phytotherapy research : PTR 20090301
Title: [Simultaneous determination of four alkaloids in Lindera aggregate by high performance liquid chromatography].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090301
Title: Simultaneous determination of four alkaloids in Lindera aggregata by ultra-high-pressure liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. A 20081128
Title: Antioxidant and pro-oxidant properties of boldine on hippocampal slices exposed to oxygen-glucose deprivation in vitro.
Journal: Neurotoxicology 20081101
Title: Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers.
Journal: Bioorganic & medicinal chemistry 20070515
Title: Advances in development of dopaminergic aporphinoids.
Journal: Journal of medicinal chemistry 20070125
Title: Antihyperglycemic effect of aporphines and their derivatives in normal and diabetic rats.
Journal: Planta medica 20061001
Title: Are extraction methods in quantitative assays of pharmacopoeia monographs exhaustive? A comparison with pressurized liquid extraction.
Journal: Planta medica 20061001
Title: Antinociceptive and free radical scavenging activities of alkaloids isolated from Lindera angustifolia Chen.
Journal: Journal of ethnopharmacology 20060719
Title: Sensitive quantification of apomorphine in human plasma using a LC-ESI-MS-MS method.
Journal: Therapeutic drug monitoring 20060601
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Boldine and its antioxidant or health-promoting properties.
Journal: Chemico-biological interactions 20060105
Title: 8-NH2-boldine, an antagonist of alpha1A and alpha1B adrenoceptors without affinity for the alpha1D subtype: structural requirements for aporphines at alpha1-adrenoceptor subtypes.
Journal: Planta medica 20051001
Title: [Alkaloids from the root of Lindera angustifolia].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20051001
Title: Effect of boldine, secoboldine, and boldine methine on angiotensin II-induced neutrophil recruitment in vivo.
Journal: Journal of leukocyte biology 20050901
Title: Photostability and photoprotection factor of boldine and glaucine.
Journal: Journal of photochemistry and photobiology. B, Biology 20050701
Title: Structure-affinity relationships of halogenated predicentrine and glaucine derivatives at D1 and D2 dopaminergic receptors: halogenation and D1 receptor selectivity.
Journal: Bioorganic & medicinal chemistry 20050601
Title: Photochemistry of phytoalexins containing phenalenone-like chromophores: photophysics and singlet oxygen photosensitizing properties of the plant oxoaporphine alkaloid oxoglaucine.
Journal: Photochemistry and photobiology 20050101
Title: Reactive oxygen species (ROS) generation inhibited by aporphine and phenanthrene alkaloids semi-synthesized from natural boldine.
Journal: Chemical & pharmaceutical bulletin 20040601
Title: Alkaloids from Cassytha filiformis and related aporphines: antitrypanosomal activity, cytotoxicity, and interaction with DNA and topoisomerases.
Journal: Planta medica 20040501
Title: A novel alkaloid antioxidant, Boldine and synthetic antioxidant, reduced form of RU486, inhibit the oxidation of LDL in-vitro and atherosclerosis in vivo in LDLR(-/-) mice.
Journal: Atherosclerosis 20040401
Title: Inhibitory action of conventional food-grade natural antioxidants and of natural antioxidants of new development on the thermal-induced oxidation of cholesterol.
Journal: International journal of food sciences and nutrition 20040301
Title: Protective role of Scoparia dulcis plant extract on brain antioxidant status and lipidperoxidation in STZ diabetic male Wistar rats.
Journal: BMC complementary and alternative medicine 20040101
Title: Spectroscopic study of antileishmanial drug incubated in the promastigotes of Leishmania mexicana.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20031101
Title: Sipaucins A-C, sesquiterpenoids from Siparuna pauciflora.
Journal: Phytochemistry 20030601
Title: Free-radical scavengers and antioxidants from Peumus boldus Mol. ('Boldo').
Journal: Free radical research 20030401
Title: Effects of some antioxidative aporphine derivatives on striatal dopaminergic transmission and on MPTP-induced striatal dopamine depletion in B6CBA mice.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030201
Title: Protection against UVB irradiation by natural filters extracted from lichens.
Journal: Journal of photochemistry and photobiology. B, Biology 20021101
Title: Affinity profile at alpha(1)- and alpha(2)-adrenoceptor subtypes and in vitro cardiovascular actions of (+)-boldine.
Journal: European journal of pharmacology 20020517
Title: Structure-activity relationship studies with (+/-)-nantenine derivatives for alpha1-adrenoceptor antagonist activity.
Journal: European journal of pharmacology 20020222
Title: Protective effect of boldine on dopamine-induced membrane permeability transition in brain mitochondria and viability loss in PC12 cells.
Journal: Biochemical pharmacology 20020201
Title: Chemoprotective activity of boldine: modulation of drug-metabolizing enzymes.
Journal: Die Pharmazie 20010301
Title: Release of intermediate reactive hydrogen peroxide by macrophage cells activated by natural products.
Journal: Biological & pharmaceutical bulletin 20010201
Title: Halogenated boldine derivatives with enhanced monoamine receptor selectivity.
Journal: Journal of natural products 20000401
Title: Antipoliovirus structure-activity relationships of some aporphine alkaloids.
Journal: Journal of natural products 19980401
Title: Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
Journal: Journal of natural products 19910101
Title: Screening for new compounds with antiherpes activity.
Journal: Antiviral research 19841001
Title: Zhao H , et al. Boldine isolated from Litsea cubeba inhibits bone resorption by suppressing the osteoclast differentiation in collagen-induced arthritis. Int Immunopharmacol. 2017 Oct;51:114-123.
