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550-70-9,MFCD00039044
Catalog No.:AA00DEFV

550-70-9 | (E)-2-(3-(Pyrrolidin-1-yl)-1-(p-tolyl)prop-1-en-1-yl)pyridine hydrochloride

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25mg
>98%(HPLC)powder
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$78.00   $55.00
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100mg
>98%(HPLC)powder
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$236.00   $165.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DEFV
Chemical Name:
(E)-2-(3-(Pyrrolidin-1-yl)-1-(p-tolyl)prop-1-en-1-yl)pyridine hydrochloride
CAS Number:
550-70-9
Molecular Formula:
C19H23ClN2
Molecular Weight:
314.8523
MDL Number:
MFCD00039044
SMILES:
Cc1ccc(cc1)/C(=C\CN1CCCC1)/c1ccccn1.Cl
NSC Number:
757361
Properties
Computed Properties
 
Complexity:
336  
Covalently-Bonded Unit Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  

Literature

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Title: Simultaneous determination of triprolidine and pseudoephedrine in human plasma by liquid chromatography-ion trap mass spectrometry.

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Title: Transport of hydroxyzine and triprolidine across bovine olfactory mucosa: role of passive diffusion in the direct nose-to-brain uptake of small molecules.

Journal: International journal of pharmaceutics 20050930

Title: Enhanced efficacy of triprolidine by transdermal application of the EVA matrix system in rabbits and rats.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050901

Title: Simultaneous analysis of the H1-antihistamine acrivastine and the decongestant pseudoephedrine hydrochloride by high-performance liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20050401

Title: Antihistamine effects of triprolidine from the transdermal administration of the TPX matrix in rats.

Journal: Archives of pharmacal research 20050101

Title: Adsorptive stripping voltammetric determination of triprolidine hydrochloride in pharmaceutical tablets.

Journal: Farmaco (Societa chimica italiana : 1989) 20050101

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Journal: European journal of medicinal chemistry 20041101

Title: Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein.

Journal: The Journal of biological chemistry 20040813

Title: New plastic membrane and carbon paste ion selective electrodes for the determination of triprolidine.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040701

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Title: Enhanced transdermal delivery of triprolidine from the ethylene-vinyl acetate matrix.

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Journal: Brain research 20020906

Title: Controlled release of triprolidine using ethylene-vinyl acetate membrane and matrix systems.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020901

Title: Endogenous histamine in the medial septum-diagonal band complex increases the release of acetylcholine from the hippocampus: a dual-probe microdialysis study in the freely moving rat.

Journal: The European journal of neuroscience 20020501

Title: Transdermal delivery of triprolidine using TPX polymer membrane.

Journal: International journal of pharmaceutics 20020320

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Title: Application of TPX polymer membranes for the controlled release of triprolidine.

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Title: The effects of single and repeated administration of ebastine on cognition and psychomotor performance in comparison to triprolidine and placebo in healthy volunteers.

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Title: Angina associated with pseudoephedrine.

Journal: Annals of emergency medicine 19810401

Title: A Double-blind crossover trial of pseudoephedrine and triprolidine, alone and in combination, for the treatment of allergenic rhinitis.

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Tags:550-70-9 Molecular Formula|550-70-9 MDL|550-70-9 SMILES|550-70-9 (E)-2-(3-(Pyrrolidin-1-yl)-1-(p-tolyl)prop-1-en-1-yl)pyridine hydrochloride