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Title: Conversion of cholic acid and chenodeoxycholic acid into their 7-oxo derivatives by Bacteroides intestinalis AM-1 isolated from human feces.
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Title: Intestinal flora induces the expression of Cyp3a in the mouse liver.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20090401
Title: Switch from Mnt-Max to Myc-Max induces p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes.
Journal: Hepatology (Baltimore, Md.) 20090301
Title: Mechanism of vitamin D receptor inhibition of cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090301
Title: 3α-Hydr-oxy-N-(3-hydroxy-prop-yl)-5β-cholan-24-amide.
Journal: Acta crystallographica. Section E, Structure reports online 20090301
Title: Identification of tumor promotion marker genes for predicting tumor promoting potential of chemicals in BALB/c 3T3 cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090201
Title: Faecal steroid excretion in humans is affected by calcium supplementation and shows gender-specific differences.
Journal: European journal of nutrition 20090201
Title: Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines.
Journal: The Journal of biological chemistry 20090130
Title: Formation and biliary excretion of glutathione conjugates of bile acids in the rat as shown by liquid chromatography/electrospray ionization-linear ion trap mass spectrometry.
Journal: Analytical biochemistry 20090115
Title: Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway.
Journal: The Biochemical journal 20090101
Title: Lithocholic acid as a biomarker of intrahepatic cholestasis of pregnancy during ursodeoxycholic acid treatment.
Journal: Annals of clinical biochemistry 20090101
Title: Bear bile: dilemma of traditional medicinal use and animal protection.
Journal: Journal of ethnobiology and ethnomedicine 20090101
Title: The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.
Journal: Nuclear receptor signaling 20090101
Title: Function of retinoic acid receptors during embryonic development.
Journal: Nuclear receptor signaling 20090101
Title: Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism.
Journal: Nuclear receptor signaling 20090101
Title: Ciprofloxacin suppresses Cyp3a in mouse liver by reducing lithocholic acid-producing intestinal flora.
Journal: Drug metabolism and pharmacokinetics 20090101
Title: Regulation of bile acid and cholesterol metabolism by PPARs.
Journal: PPAR research 20090101
Title: Circadian dysregulation disrupts bile acid homeostasis.
Journal: PloS one 20090101
Title: Discrimination of carcinogens by hepatic transcript profiling in rats following 28-day administration.
Journal: Cancer informatics 20090101
Title: Remarkably stable inclusion complexes with heptakis-[6-deoxy-6-(2-aminoethylsulfanyl)]-beta-cyclodextrin.
Journal: Organic & biomolecular chemistry 20081221
Title: Tumor endothelial cell targeted cyclic RGD-modified heparin derivative: inhibition of angiogenesis and tumor growth.
Journal: Pharmaceutical research 20081201
Title: Technical modification of the Balb/c 3T3 cell transformation assay: the use of serum-reduced medium to optimise the practicability of the protocol.
Journal: Alternatives to laboratory animals : ATLA 20081201
Title: Introducing N-glycans into natural products through a chemoenzymatic approach.
Journal: Carbohydrate research 20081124
Title: Immunoprecipitation and MALDI-MS identification of lithocholic acid-tagged proteins in liver of bile duct-ligated rats.
Journal: Journal of lipid research 20081101
Title: Structural determinants of monohydroxylated bile acids to activate beta 1 subunit-containing BK channels.
Journal: Journal of lipid research 20081101
Title: Association between fecal bile acids and colorectal cancer: a meta-analysis of observational studies.
Journal: Yonsei medical journal 20081031
Title: Bile components and amino acids affect survival of the newly excysted juvenile Clonorchis sinensis in maintaining media.
Journal: Parasitology research 20081001
Title: Role of vitamin D receptor in the lithocholic acid-mediated CYP3A induction in vitro and in vivo.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20081001
Title: New lithocholic and chenodeoxycholic piperazinylcarboxamides with antiproliferative and pro-apoptotic effects on human cancer cell lines.
Journal: Bioorganic & medicinal chemistry 20080915
Title: Expression and regulation of the vitamin D receptor in the zebrafish, Danio rerio.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080901
Title: PU.1 and bacterial metabolites regulate the human gene CAMP encoding antimicrobial peptide LL-37 in colon epithelial cells.
Journal: Molecular immunology 20080901
Title: Bile acids repress E-cadherin through the induction of Snail and increase cancer invasiveness in human hepatobiliary carcinoma.
Journal: Cancer science 20080901
Title: Induction of differentiation of myeloid leukemia cells in primary culture in response to lithocholic acid acetate, a bile acid derivative, and cooperative effects with another differentiation inducer, cotylenin A.
Journal: Leukemia research 20080701
Title: Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701
Title: Lithocholic acid down-regulation of NF-kappaB activity through vitamin D receptor in colonic cancer cells.
Journal: The Journal of steroid biochemistry and molecular biology 20080701
Title: Determination of bile acids in human serum by on-line restricted access material-ultra high-performance liquid chromatography-mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080615
Title: Design and synthesis of hydroxy-alkynoic acids and their methyl esters as novel activators of BK channels.
Journal: Bioorganic & medicinal chemistry letters 20080601
Title: Synthesis and structural characteristics of lithocholate triads: steroid-type channels occupied by spacer fragments.
Journal: Acta crystallographica. Section B, Structural science 20080601
Title: Bile acids and derivatives, their nuclear receptors FXR, PXR and ligands: role in health and disease and their therapeutic potential.
Journal: Anti-cancer agents in medicinal chemistry 20080601
Title: A novel role for the retinoic acid-catabolizing enzyme CYP26A1 in Barrett's associated adenocarcinoma.
Journal: Oncogene 20080508
Title: Store-operated Ca(2+) channels and Stromal Interaction Molecule 1 (STIM1) are targets for the actions of bile acids on liver cells.
Journal: Biochimica et biophysica acta 20080501
Title: Packed-column capillary electrochromatography and capillary electrochromatography-mass spectrometry using a lithocholic acid stationary phase.
Journal: Electrophoresis 20080501
Title: Lithocholic acid derivatives act as selective vitamin D receptor modulators without inducing hypercalcemia.
Journal: Journal of lipid research 20080401
Title: Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.
Journal: Journal of medicinal chemistry 20080327
Title: Large and stable transmembrane pores from guanosine-bile acid conjugates.
Journal: Journal of the American Chemical Society 20080312
Title: The second transmembrane domain of the large conductance, voltage- and calcium-gated potassium channel beta(1) subunit is a lithocholate sensor.
Journal: FEBS letters 20080305
Title: Hepatobiliary effects of cholic and lithocholic acids: experimental study in hamsters.
Journal: Pediatric surgery international 20080301
Title: Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080301
Title: In vitro gene expression analysis of hepatotoxic drugs in rat primary hepatocytes.
Journal: Journal of applied toxicology : JAT 20080301
Title: RNA interference in mammalia cells by RNA-3'-PNA chimeras.
Journal: International journal of molecular sciences 20080301
Title: Biotransformation of lithocholic acid by rat hepatic microsomes: metabolite analysis by liquid chromatography/mass spectrometry.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080201
Title: The use of High Performance Thin-Layer Chromatography to determine the role of membrane lipid composition in bile salt-induced kidney cell damage.
Journal: Journal of pharmacological and toxicological methods 20080101
Title: Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics.
Journal: PloS one 20080101
Title: Evolution of pharmacologic specificity in the pregnane X receptor.
Journal: BMC evolutionary biology 20080101
Title: Effect of colonic bacterial metabolites on Caco-2 cell paracellular permeability in vitro.
Journal: Nutrition and cancer 20080101
Title: Peroxisome proliferator-activated receptor alpha activates cyclooxygenase-2 gene transcription through bile acid transport in human colorectal cancer cell lines.
Journal: Journal of gastroenterology 20080101
Title: Production and characterization of a monoclonal antibody to capture proteins tagged with lithocholic acid.
Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080101
Title: Role of bile acid secretion in human colorectal cancer.
Journal: Wiener medizinische Wochenschrift (1946) 20080101
Title: Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases.
Journal: Wiener medizinische Wochenschrift (1946) 20080101
Title: Insights into the roles of gut microbes in obesity.
Journal: Interdisciplinary perspectives on infectious diseases 20080101
Title: Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis.
Journal: Clinical and experimental gastroenterology 20080101
Title: Isolation and chemical synthesis of a major, novel biliary bile acid in the common wombat (Vombatus ursinus): 15alpha-hydroxylithocholic acid.
Journal: Journal of lipid research 20071201
Title: Genetic variations of VDR/NR1I1 encoding vitamin D receptor in a Japanese population.
Journal: Drug metabolism and pharmacokinetics 20071201
Title: Synthesis, characterization, and receptor interaction profiles of enantiomeric bile acids.
Journal: Journal of medicinal chemistry 20071129
Title: ME3738 protects against lithocholic acid-induced hepatotoxicity, which is associated with enhancement of biliary bile acid and cholesterol output.
Journal: European journal of pharmacology 20071128
Title: Simultaneous characterization of bile acid, sterols, and determination of acylglycerides in feces from soluble cellulose-fed hamsters using HPLC with evaporative light-scattering detection and APCI-MS.
Journal: Journal of agricultural and food chemistry 20071128
Title: p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis.
Journal: The Journal of biological chemistry 20071123
Title: Use of selected chemical markers in combination with a multiple regression model to assess the contribution of domesticated animal sources of fecal pollution in the environment.
Journal: Chemosphere 20071101
Title: Activation of nuclear factor (erythroid-2 like) factor 2 by toxic bile acids provokes adaptive defense responses to enhance cell survival at the emergence of oxidative stress.
Journal: Molecular pharmacology 20071101
Title: Protective effects of ursodeoxycholic acid on chenodeoxycholic acid-induced liver injury in hamsters.
Journal: World journal of gastroenterology 20071007
Title: Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells.
Journal: Drug metabolism and pharmacokinetics 20071001
Title: Colesevelam hydrochloride: reducing atherosclerotic coronary heart disease risk factors.
Journal: Vascular health and risk management 20071001
Title: Characterization of an oligomeric carbonyl reductase of dog liver: its identity with peroxisomal tetrameric carbonyl reductase.
Journal: Biological & pharmaceutical bulletin 20070901
Title: Role of bile bacteria in gallbladder carcinoma.
Journal: Hepato-gastroenterology 20070901
Title: Lithocholic acid induction of the FGF19 promoter in intestinal cells is mediated by PXR.
Journal: World journal of gastroenterology 20070821
Title: Beta1 (KCNMB1) subunits mediate lithocholate activation of large-conductance Ca2+-activated K+ channels and dilation in small, resistance-size arteries.
Journal: Molecular pharmacology 20070801
Title: Retinoic acid-induced glandular differentiation of the oesophagus.
Journal: Gut 20070701
Title: Human cecal bile acids: concentration and spectrum.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701
Title: Lithocholic acid can carry out in vivo functions of vitamin D.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20070612
Title: Anchoring cationic amphiphiles for nucleotide delivery: significance of DNA release from cationic liposomes for transfection.
Journal: Biological & pharmaceutical bulletin 20070601
Title: Structural and chemical profiling of the human cytosolic sulfotransferases.
Journal: PLoS biology 20070501
Title: Antiangiogenic and apoptotic properties of a novel amphiphilic folate-heparin-lithocholate derivative having cellular internality for cancer therapy.
Journal: Pharmaceutical research 20070401
Title: Identification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue.
Journal: Environmental health perspectives 20070401
Title: Coordinated defence and the liver.
Journal: Clinical medicine (London, England) 20070401
Title: Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301
Title: LC/ESI-tandem mass spectrometric determination of bile acid 3-sulfates in human urine 3beta-Sulfooxy-12alpha-hydroxy-5beta-cholanoic acid is an abundant nonamidated sulfate.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201
Title: Activation of LXRs prevents bile acid toxicity and cholestasis in female mice.
Journal: Hepatology (Baltimore, Md.) 20070201
Title: Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070101
Title: In silico prediction of pregnane X receptor activators by machine learning approaches.
Journal: Molecular pharmacology 20070101
Title: Liver dysfunction associated with artificial nutrition in critically ill patients.
Journal: Critical care (London, England) 20070101
Title: A synthetic supramolecular construct modulating protein assembly in cells.
Journal: Angewandte Chemie (International ed. in English) 20070101
Title: [A new synthesis of cerebrosterol and its 24-epimer from lithocholic acid].
Journal: Bioorganicheskaia khimiia 20070101
Title: Intrahepatic cholestasis of pregnancy.
Journal: Orphanet journal of rare diseases 20070101
Title: Genetic variability in CYP3A4 and CYP3A5 in primary liver, gastric and colorectal cancer patients.
Journal: BMC cancer 20070101
Title: High-performance functional ecopolymers based on flora and fauna.
Journal: Chemical record (New York, N.Y.) 20070101
Title: A Multipurpose receptor composed of promiscuous proteins. Analyte detection through pattern recognition.
Journal: Bioconjugate chemistry 20070101
Title: Functional evolution of the vitamin D and pregnane X receptors.
Journal: BMC evolutionary biology 20070101
Title: Bile acid analysis in biliary tract cancer.
Journal: Yonsei medical journal 20061231
Title: Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta.
Journal: Biochemical and biophysical research communications 20061110
Title: Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica).
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20061101
Title: Bile acids induce adhesion molecule expression in endothelial cells through activation of reactive oxygen species, NF-kappaB, and p38.
Journal: American journal of physiology. Heart and circulatory physiology 20060801
Title: Chenodeoxycholic acid-mediated activation of the farnesoid X receptor negatively regulates hydroxysteroid sulfotransferase.
Journal: Drug metabolism and pharmacokinetics 20060801
Title: Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation.
Journal: Pharmaceutical research 20060701
Title: Role for enhanced faecal excretion of bile acid in hydroxysteroid sulfotransferase-mediated protection against lithocholic acid-induced liver toxicity.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20060701
Title: Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.
Journal: Journal of lipid research 20060601
Title: Selective targeting of liposomes to macrophages using a ligand with high affinity for the macrophage scavenger receptor class A.
Journal: Current drug discovery technologies 20060601
Title: 19nor-1,25-dihydroxyvitamin D2 specifically induces CYP3A9 in rat intestine more strongly than 1,25-dihydroxyvitamin D3 in vivo and in vitro.
Journal: Molecular pharmacology 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds.
Journal: Current drug metabolism 20060501
Title: Bile acid profiles by capillary electrophoresis in intrahepatic cholestasis of pregnancy.
Journal: Clinical science (London, England : 1979) 20060401
Title: Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 cells doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060301
Title: Effect of colitis and ileoanal pouch on biliary enrichment of ursodeoxycholic acid in primary sclerosing cholangitis.
Journal: Digestive diseases and sciences 20060301
Title: Vitamin D receptor: ligand recognition and allosteric network.
Journal: Journal of medicinal chemistry 20060223
Title: First synthesis of free cholesterol-BODIPY conjugates.
Journal: The Journal of organic chemistry 20060217
Title: Lithocholic acid analogues, new and potent alpha-2,3-sialyltransferase inhibitors.
Journal: Chemical communications (Cambridge, England) 20060214
Title: Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
Journal: The American journal of pathology 20060201
Title: Studies of serum and feces bile acids determination by gas chromatography-mass spectrometry.
Journal: Rinsho byori. The Japanese journal of clinical pathology 20060201
Title: Biochemical and physiological properties of a novel series of long-acting insulin analogs obtained by acylation with cholic acid derivatives.
Journal: Pharmaceutical research 20060101
Title: Bile acid metabolism in extrahepatic biliary atresia: lithocholic acid in stored dried blood collected at neonatal screening.
Journal: Upsala journal of medical sciences 20060101
Title: [The induction of CYP3A regulated by pregnane X receptor and its significance in drug metabolism].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060101
Title: Enzymatic production of bile Acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses.
Journal: Molecular pharmaceutics 20060101
Title: Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro.
Journal: Molecular cancer 20060101
Title: A bioconjugate approach toward squalamine mimics: Insight into the mechanism of biological action.
Journal: Bioconjugate chemistry 20060101
Title: [Synthesis of (24S)-hydroxy- and (24S)-24,25-epoxycholesterol analogues, potential agonists of nuclear LXR receptors].
Journal: Bioorganicheskaia khimiia 20060101
Title: Study of the Urinary Ratio of 6 beta-Hydroxycortisol/Cortisol as a Biomarker of CYP3A4 Activity in Egyptian Patients with Chronic Liver Diseases.
Journal: Biomarker insights 20060101
Title: Detection of initiating as well as promoting activity of chemicals by a novel cell transformation assay using v-Ha-ras-transfected BALB/c 3T3 cells (Bhas 42 cells).
Journal: Mutation research 20051207
Title: An inter-laboratory collaborative study by the Non-Genotoxic Carcinogen Study Group in Japan, on a cell transformation assay for tumour promoters using Bhas 42 cells.
Journal: Alternatives to laboratory animals : ATLA 20051201
Title: Synthesis of nitrogen- and oxygen-containing macrocycles--derivatives of lithocholic Acid.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20051118
Title: Enhancement of ligand-dependent vitamin D receptor transactivation by the cardiotonic steroid bufalin.
Journal: Biochemical pharmacology 20051115
Title: Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus.
Journal: The Journal of biological chemistry 20051111
Title: Differentiated quantification of human bile acids in serum by high-performance liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105
Title: Enhanced effects of lithocholic acid incorporation into liquid-crystalline biopolymer poly(coumaric acid) on structural ordering and cell adhesion.
Journal: Biomaterials 20051101
Title: Specificity of receptor-ligand interactions and their effect on dimerisation as observed by electrospray mass spectrometry: bile acids form stable adducts to the RXRalpha.
Journal: Journal of mass spectrometry : JMS 20051101
Title: Role of FXR in regulating bile acid homeostasis and relevance for human diseases.
Journal: Current drug targets. Immune, endocrine and metabolic disorders 20050901
Title: Promoter-, cell-, and ligand-specific transactivation responses of the VDRB1 isoform.
Journal: Biochemical and biophysical research communications 20050819
Title: CAR and PXR: xenosensors of endocrine disrupters?
Journal: Chemico-biological interactions 20050815
Title: CAR, the continuously advancing receptor, in drug metabolism and disease.
Journal: Current drug metabolism 20050801
Title: Nanoencapsulation of a crystalline drug.
Journal: International journal of pharmaceutics 20050725
Title: Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M(3) receptor-dependent.
Journal: European journal of pharmacology 20050704
Title: Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701
Title: Bioactivation of morphine in human liver: isolation and identification of morphinone, a toxic metabolite.
Journal: Biological & pharmaceutical bulletin 20050701
Title: Vitamin D receptor-dependent regulation of colon multidrug resistance-associated protein 3 gene expression by bile acids.
Journal: The Journal of biological chemistry 20050617
Title: Pregnane X receptor-agonists down-regulate hepatic ATP-binding cassette transporter A1 and scavenger receptor class B type I.
Journal: Biochemical and biophysical research communications 20050617
Title: Comparative binding study of steroidal adenine with flavin and uracil derivatives.
Journal: Bioorganic & medicinal chemistry letters 20050602
Title: Enzymatic properties of a member (AKR1C19) of the aldo-keto reductase family.
Journal: Biological & pharmaceutical bulletin 20050601
Title: Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4.
Journal: Journal of cellular biochemistry 20050401
Title: Chemical synthesis of 24-beta-D-galactopyranosides of bile acids: a new type of bile acid conjugates in human urine.
Journal: Chemistry and physics of lipids 20050401
Title: Generation of a single-chain Fv fragment for the monitoring of deoxycholic acid residues anchored on endogenous proteins.
Journal: Steroids 20050401
Title: Increasing ursodeoxycholic acid in the enterohepatic circulation of pigs through the administration of living bacteria.
Journal: The British journal of nutrition 20050401
Title: Novel pathways of bile acid metabolism involving CYP3A4.
Journal: Biochimica et biophysica acta 20050221
Title: Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050101
Title: Selective activation of vitamin D receptor by lithocholic acid acetate, a bile acid derivative.
Journal: Journal of lipid research 20050101
Title: Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice.
Journal: Hepatology (Baltimore, Md.) 20050101
Title: Affinity capture of a mammalian DNA polymerase beta by inhibitors immobilized to resins used in solid-phase organic synthesis.
Journal: Bioconjugate chemistry 20050101
Title: Properties of a thermostable extracellular lipase from Bacillus megaterium AKG-1.
Journal: Journal of basic microbiology 20050101
Title: Inhibition of MRP1-mediated efflux in human erythrocytes by mono-anionic bile salts.
Journal: Anticancer research 20050101
Title: Tandem machine learning for the identification of genes regulated by transcription factors.
Journal: BMC bioinformatics 20050101
Title: Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors).
Journal: Nuclear receptor 20050101
Title: Effect of dried plums on colon cancer risk factors in rats.
Journal: Nutrition and cancer 20050101
Title: Vitamin D receptor regulation of the steroid/bile acid sulfotransferase SULT2A1.
Journal: Methods in enzymology 20050101
Title: Effects of a 3-mo consumption of short-chain fructo-oligosaccharides on parameters of colorectal carcinogenesis in patients with or without small or large colorectal adenomas.
Journal: Nutrition and cancer 20050101
Title: A nonenzymatic modification of the amino-terminal domain of histone H3 by bile acid acyl adenylate.
Journal: The Journal of biological chemistry 20041231
Title: Determination of underivatised sterols and bile acid trimethyl silyl ether methyl esters by gas chromatography-mass spectrometry-single ion monitoring in faeces.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225
Title: Bile acid amidoalcohols: simple organogelators.
Journal: Biosensors & bioelectronics 20041215
Title: Effects of bile acids on proliferation and production of proteinase activity of Uronema marinum (Ciliophora: Scuticociliatida).
Journal: Diseases of aquatic organisms 20041213
Title: Megalin and cubilin expression in gallbladder epithelium and regulation by bile acids.
Journal: Journal of lipid research 20041201
Title: The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
Journal: The Journal of biological chemistry 20041119
Title: Modified oligonucleotides containing lithocholic acid in their backbones: their enhanced cellular uptake and their mimicking of hairpin structures.
Journal: Chembiochem : a European journal of chemical biology 20041105
Title: Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells.
Journal: Bioorganic & medicinal chemistry letters 20041004
Title: Detoxification of lithocholic acid, a toxic bile acid: relevance to drug hepatotoxicity.
Journal: Drug metabolism reviews 20041001
Title: DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon.
Journal: Cancer letters 20040830
Title: Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.
Journal: Biochemistry 20040824
Title: Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting human insulins.
Journal: Biochemistry 20040525
Title: Feed-forward regulation of bile acid detoxification by CYP3A4: studies in humanized transgenic mice.
Journal: The Journal of biological chemistry 20040319
Title: The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion.
Journal: The Journal of biological chemistry 20040305
Title: A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification.
Journal: Molecular pharmacology 20040201
Title: Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation.
Journal: Journal of lipid research 20040101
Title: Structural determinants for vitamin D receptor response to endocrine and xenobiotic signals.
Journal: Molecular endocrinology (Baltimore, Md.) 20040101
Title: Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs.
Journal: Lipids in health and disease 20040101
Title: Comparison among fecal secondary bile acid levels, fecal microbiota and Clostridium scindens cell numbers in Japanese.
Journal: Microbiology and immunology 20040101
Title: Fluorescence resonance energy transfer in a novel cyclodextrin-peptide conjugate for detecting steroid molecules.
Journal: Bioorganic & medicinal chemistry letters 20031215
Title: Synthesis of ester-linked lithocholic acid dimers.
Journal: Steroids 20031201
Title: Sex steroid receptors, secondary bile acids and colorectal cancer. A possible mechanism of interaction.
Journal: Panminerva medica 20031201
Title: Induction of ABCC3 (MRP3) by pregnane X receptor activators.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101
Title: Effect of tartaric acid and dietary fibre from sun-dried raisins on colonic function and on bile acid and volatile fatty acid excretion in healthy adults.
Journal: The British journal of nutrition 20031001
Title: Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.
Journal: Hepatology (Baltimore, Md.) 20030801
Title: Activation of muscarinic receptor signaling by bile acids: physiological and medical implications.
Journal: Digestive diseases and sciences 20030801
Title: [Functional analysis of drug metabolizing enzymes using gene knockout animals].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030701
Title: Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity.
Journal: The Journal of biological chemistry 20030516
Title: Effects on cell proliferation, activator protein-1 and genotoxicity by fecal water from patients with colorectal adenomas.
Journal: Scandinavian journal of gastroenterology 20030501
Title: A G protein-coupled receptor responsive to bile acids.
Journal: The Journal of biological chemistry 20030314
Title: Opposing effects of butyrate and bile acids on apoptosis of human colon adenoma cells: differential activation of PKC and MAP kinases.
Journal: British journal of cancer 20030310
Title: New insights into the mechanisms of vitamin D action.
Journal: Journal of cellular biochemistry 20030301
Title: Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20030204
Title: Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7.
Journal: Biochemical pharmacology 20030201
Title: Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone.
Journal: Chemico-biological interactions 20030201
Title: Influence of breast feeding, and adapted and hydrolyzed formulas on biliary bile acids in newborn guinea pigs.
Journal: Biology of the neonate 20030101
Title: Urinary excretion of bile acids in bile duct-ligated rats.
Journal: Journal of gastroenterology 20030101
Title: Does ursodeoxycholic acid change the proliferation of the colorectal mucosa?. A randomized, placebo-controlled study.
Journal: Digestion 20030101
Title: Selective interaction of bile acids with muscarinic receptors: a case of molecular mimicry.
Journal: European journal of pharmacology 20021220
Title: Identification of membrane-type receptor for bile acids (M-BAR).
Journal: Biochemical and biophysical research communications 20021115
Title: Rapid and improved method for the determination of bile acids in human feces using MS.
Journal: Lipids 20021101
Title: Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
Journal: Proceedings of the National Academy of Sciences of the United States of America 20021015
Title: Functional interaction of lithocholic acid conjugates with M3 muscarinic receptors on a human colon cancer cell line.
Journal: Biochimica et biophysica acta 20021009
Title: Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA.
Journal: The Journal of biological chemistry 20021004
Title: Bile acids stimulate invasion and haptotaxis in human colorectal cancer cells through activation of multiple oncogenic signaling pathways.
Journal: Oncogene 20021003
Title: Lithocholylcholine, a bile acid/acetylcholine hybrid, is a muscarinic receptor antagonist.
Journal: The Journal of pharmacology and experimental therapeutics 20021001
Title: The effect of charge reversal mutations in the alpha-helical region of liver fatty acid binding protein on the binding of fatty-acyl CoAs, lysophospholipids and bile acids.
Journal: Molecular and cellular biochemistry 20021001
Title: Synthesis of [3,4-(13)c(2)]-enriched bile salts as NMR probes of protein-ligand interactions.
Journal: The Journal of organic chemistry 20020920
Title: Kinetic characterization of native and cysteine 112-modified glutathione S-transferase A1-1: reassessment of nonsubstrate ligand binding.
Journal: Biochemistry 20020910
Title: A monoclonal antibody-based enzyme-linked immunosorbent assay of glycolithocholic acid sulfate in human urine for liver function test.
Journal: Steroids 20020901
Title: Intestinal bile acids can bind to and activate the vitamin D receptor.
Journal: Nutrition reviews 20020901
Title: Calcium affects biomarkers of colon carcinogenesis after right hemicolectomy.
Journal: European journal of clinical investigation 20020901
Title: Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity.
Journal: The Journal of biological chemistry 20020830
Title: Deoxycholic acid conjugates are muscarinic cholinergic receptor antagonists.
Journal: Pharmacology 20020801
Title: Intestinal absorption and biliary secretion of ursodeoxycholic acid and its taurine conjugate.
Journal: European journal of clinical investigation 20020801
Title: Advantages of in vitro cytotoxicity testing by using primary rat hepatocytes in comparison with established cell lines.
Journal: The Journal of toxicological sciences 20020801
Title: Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling.
Journal: The Journal of biological chemistry 20020705
Title: A prospective study of serum bile acid concentrations and colorectal cancer risk in post-menopausal women on the island of Guernsey.
Journal: British journal of cancer 20020605
Title: Postprandial changes in serum unconjugated bile acid concentrations in healthy beagles.
Journal: American journal of veterinary research 20020601
Title: Effect of colestimide on absorption of unconjugated bile acids in the rat jejunum.
Journal: Journal of gastroenterology and hepatology 20020601
Title: Vitamin D receptor as an intestinal bile acid sensor.
Journal: Science (New York, N.Y.) 20020517
Title: Relationship between asymptomatic hypercholanaemia of pregnancy and progesterone metabolism.
Journal: Clinical science (London, England : 1979) 20020501
Title: Characterization of cloned mouse Na+/taurocholate cotransporting polypeptide by transient expression in COS-7 cells.
Journal: Bioscience, biotechnology, and biochemistry 20020501
Title: Photoaffinity labeling of human retinoid X receptor beta (RXRbeta) with 9-cis-retinoic acid: identification of phytanic acid, docosahexaenoic acid, and lithocholic acid as ligands for RXRbeta.
Journal: Biochemistry 20020416
Title: Characterization of rat liver bile acid acyl glucuronosyltransferase.
Journal: Steroids 20020301
Title: Unconjugated bile acids modulate adult and neonatal neutrophil chemotaxis induced in vitro by N-formyl-met-leu-phe-peptide.
Journal: Pediatric research 20020301
Title: Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor.
Journal: Journal of lipid research 20020301
Title: Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases alpha and beta.
Journal: Bioorganic & medicinal chemistry letters 20020211
Title: Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism.
Journal: Toxicology letters 20020207
Title: A pharmacophore for human pregnane X receptor ligands.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020101
Title: Nuclear xeno-sensors as receptors for cholestatic bile acids: the second line of defense.
Journal: Hepatology (Baltimore, Md.) 20020101
Title: [Features of composition of bile acids in duodenal bile in patients with chronic pancreatitis].
Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20020101
Title: Intrahepatic cholestasis of pregnancy: changes in maternal-fetal bile acid balance and improvement by ursodeoxycholic acid.
Journal: Annals of hepatology 20020101
Title: Anchoring and bola cationic amphiphiles for nucleotide delivery. Effects of orientation and extension of hydrophobic regions.
Journal: Bioorganic & medicinal chemistry letters 20011119
Title: Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism.
Journal: Medicinal research reviews 20011101
Title: Three-dimensional structural model analysis of the binding site of lithocholic acid, an inhibitor of DNA polymerase beta and DNA topoisomerase II.
Journal: Journal of biochemistry 20011101
Title: Carrier-mediated delivery improves the efficacy of 9-(2-phosphonylmethoxyethyl)adenine against hepatitis B virus.
Journal: Molecular pharmacology 20010901
Title: Effect of chronic administration of tauro-hyodeoxycholic acid on biliary bile acid composition and on biliary lipid secretion in humans.
Journal: Scandinavian journal of gastroenterology 20010901
Title: Effect of bile acids on formation of azoxymethane-induced aberrant crypt foci in colostomized F344 rat colon.
Journal: Cancer letters 20010828
Title: Enantioselective inhibition of the binding of rac-profens to human serum albumin induced by lithocholate.
Journal: Chirality 20010701
Title: Fetal bile acid metabolism: analysis of urinary 3beta-monohydroxy-delta(5) bile acid in preterm infants.
Journal: Biology of the neonate 20010701
Title: LUV's lipid composition modulates diffusion of bile acids.
Journal: Chemistry and physics of lipids 20010401
Title: The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20010313
Title: [Other antihyperlipidemic drugs with novel mechanism].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301
Title: Alterations in intestinal microflora, faecal bile acids and short chain fatty acids in dextran sulphate sodium-induced experimental acute colitis in rats.
Journal: European journal of gastroenterology & hepatology 20010201
Title: Modulation of inducible nitric oxide synthase expression in rat intestinal cells by colon tumor promoters.
Journal: International journal of oncology 20010101
Title: Determination of bile acids in biological fluids by liquid chromatography-electrospray tandem mass spectrometry.
Journal: Journal of lipid research 20010101
Title: Visualization of the transport of primary and secondary bile acids across liver tissue in rats: in vivo study with fluorescent bile acids.
Journal: Journal of hepatology 20010101
Title: Application of photoaffinity labeling with [(3)H] all trans- and 9-cis-retinoic acids for characterization of cellular retinoic acid--binding proteins I and II.
Journal: Protein science : a publication of the Protein Society 20010101
Title: Identification of a nuclear receptor for bile acids.
Journal: Science (New York, N.Y.) 19990521
Title: Bile acids: natural ligands for an orphan nuclear receptor.
Journal: Science (New York, N.Y.) 19990521
Title: Endogenous bile acids are ligands for the nuclear receptor FXR/BAR.
Journal: Molecular cell 19990501
Title: Triterpenes as potential dimerization inhibitors of HIV-1 protease.
Journal: Biochemical and biophysical research communications 19961014
Title: Bile acids produce a generalized reduction of the catalytic activity of cytochromes P450 and other hepatic microsomal enzymes in vitro: relevance to drug metabolism in experimental cholestasis.
Journal: Journal of gastroenterology and hepatology 19960901
Title: Bile acid stimulation of early growth response gene and mitogen-activated protein kinase is protein kinase C-dependent.
Journal: The Biochemical journal 19960615
Title: Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids.
Journal: Carcinogenesis 19960301
Title: Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation.
Journal: European journal of gastroenterology & hepatology 19960301
Title: Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.
Journal: The Biochemical journal 19960115
Title: [ATPase activity of erythrocytic membrane and intraerythrocytic ionic levels in pregnancy with intrahepatic cholestasis].
Journal: Zhonghua fu chan ke za zhi 19950401
Title: Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids.
Journal: International journal of cancer 19950329
Title: Lithocholic acid inhibits the expression of HLA class I genes in colon adenocarcinoma cells. Differential effect on HLA-A, -B and -C loci.
Journal: Molecular immunology 19940601
Title: Bile acid excretion and cholesterol 7 alpha-hydroxylase expression in hypercholesterolemia-resistant rabbits.
Journal: Journal of lipid research 19931001
Title: cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family.
Journal: The Journal of biological chemistry 19930515
Title: [Studies on initiating activity of secondary bile acids for rat hepatocarcinogenesis].
Journal: [Hokkaido igaku zasshi] The Hokkaido journal of medical science 19930101
Title: Cholic acid and ursodeoxycholic acid therapy in primary biliary cirrhosis. Changes in bile acid patterns and their correlation with liver function.
Journal: European journal of clinical pharmacology 19930101
Title: Do intracellular Ca2+ activity and hepatic glutathione play a role in the pathogenesis of lithocholic acid-induced cholestasis?
Journal: Toxicology letters 19920701
Title: Comparative hepatotoxicity of cholic acid, deoxycholic acid and lithocholic acid in the rat: in vivo and in vitro studies.
Journal: Toxicology letters 19920701
Title: Pathogenesis of lithocholate-induced intrahepatic cholestasis: role of glucuronidation and hydroxylation of lithocholate.
Journal: Biochimica et biophysica acta 19920605
Title: Effects of lithocholic acid exposure throughout pregnancy on late prenatal and early postnatal development in rats.
Journal: Teratology 19910401
Title: Cholestasis induced by lithocholate and its glucuronide: their biliary excretion and metabolism.
Journal: Biochimica et biophysica acta 19910104
Title: Promotion of hepatocellular foci in female rats by chenodeoxycholic acid.
Journal: Carcinogenesis 19910101
Title: Effects of novel bile salts on cholesterol metabolism in rats and guinea-pigs.
Journal: Biochemical pharmacology 19901101
Title: A comparative study on the effect of tumor promoters on poly ADP-ribosylation in A431 cells.
Journal: International journal of cancer 19901015
Title: Enhanced preneoplastic liver lesion development under 'selection pressure' conditions after administration of deoxycholic or lithocholic acid in the initiation phase in rats.
Journal: Carcinogenesis 19900801
Title: Selective activity of several cholic acid derivatives against human immunodeficiency virus replication in vitro.
Journal: Journal of acquired immune deficiency syndromes 19890101
Title: [Effect of bile and bile acids on monoamine oxidase and acetylcholinesterase activity in the jejunum of rabbits, guinea pigs and swine].
Journal: Polskie archiwum weterynaryjne 19870101
Title: Clinical evaluation of serum 3 beta-hydroxy-5-cholenoic acid in hepatobiliary diseases.
Journal: Gastroenterologia Japonica 19861201
Title: Evidence for an ordered reaction mechanism for bile salt: 3'phosphoadenosine-5'-phosphosulfate: sulfotransferase from rhesus monkey liver that catalyzes the sulfation of the hepatotoxin glycolithocholate.
Journal: Journal of lipid research 19861101
Title: Rat liver UDP-glucuronosyltransferase. cDNA sequence and expression of a form glucuronidating 3-hydroxyandrogens.
Journal: The Journal of biological chemistry 19861025
Title: Binding of bile acids by glutathione S-transferases from rat liver.
Journal: Journal of lipid research 19860901
Title: Monkey lactate dehydrogenase-C4 as a model for the interaction of enzymes with gossypol.
Journal: Contraception 19860601
Title: Inhibition of hepatic and extrahepatic glutathione S-transferases by primary and secondary bile acids.
Journal: The Biochemical journal 19860115
Title: Inhibition of hepatic Na +, K + -adenosinetriphosphatase in taurolithocholate-induced cholestasis in the rat.
Journal: Experientia 19790915
Title: Cholestatic liver disease associated with diphenylhydantoin therapy. Possible pathogenic importance of altered bile salt metabolism.
Journal: The American journal of digestive diseases 19770301
Title: Toxicity of chenodeoxycholic acid in the rhesus monkey.
Journal: Gastroenterology 19750801
Title: Cholesterol 7alpha-hydroxylase. 2. Biochemical properties and participation of endogenous cholesterol in the assay in vitro.
Journal: European journal of biochemistry 19750616
Title: Toxicity of chenodeoxycholic acid in the nonhuman primate.
Journal: Surgery 19750601
Title: Medical treatment of gallstones.
Journal: Southern medical journal 19750101
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Title: Matsubara, T., et al., TGF-beta-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury. J Lipid Res, 2012. 53(12): p. 2698-707.
