Home Fluorides 575-04-2
575-04-2,MFCD00132980
Catalog No.:AA00ECUE

575-04-2 | 7-Methoxy-4-(trifluoromethyl)-2H-chromen-2-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$30.00   $21.00
- +
250mg
97%
in stock  
$57.00   $40.00
- +
1g
97%
in stock  
$167.00   $117.00
- +
2.5g
95%
in stock  
$247.00   $173.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ECUE
Chemical Name:
7-Methoxy-4-(trifluoromethyl)-2H-chromen-2-one
CAS Number:
575-04-2
Molecular Formula:
C11H7F3O3
Molecular Weight:
244.1667
MDL Number:
MFCD00132980
SMILES:
COc1ccc2c(c1)oc(=O)cc2C(F)(F)F
Properties
Properties
 
BP:
287.4 °C at 760 mmHg  
Form:
Solid  
MP:
111 - 113°C  
Storage:
-20 ℃;Keep in dry area;  

Computed Properties
 
Complexity:
348  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
1  
XLogP3:
2.7  

Literature

Title: Cytochrome P450-mediated hepatic metabolism of new fluorescent substrates in cats and dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Functional differences in the cytochrome P450 1 family enzymes from zebrafish (Danio rerio) using heterologously expressed proteins.

Journal: Archives of biochemistry and biophysics 20101001

Title: Effects of cytochrome P450 inhibitors on the biotransformation of fluorogenic substrates by adult male rat liver microsomes and cDNA-expressed rat cytochrome P450 isoforms.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100201

Title: Defining the in Vivo Role for cytochrome b5 in cytochrome P450 function through the conditional hepatic deletion of microsomal cytochrome b5.

Journal: The Journal of biological chemistry 20081114

Title: Identification and analysis of conserved sequence motifs in cytochrome P450 family 2. Functional and structural role of a motif 187RFDYKD192 in CYP2B enzymes.

Journal: The Journal of biological chemistry 20080801

Title: Limited applicability of 7-methoxy-4-trifluoromethylcoumarin as a CYP2C9-selective substrate.

Journal: Pharmacological reports : PR 20080101

Title: Generation and evaluation of a CYP2C9 heteroactivation pharmacophore.

Journal: The Journal of pharmacology and experimental therapeutics 20031201

Title: Cytochrome P450 fluorometric substrates: identification of isoform-selective probes for rat CYP2D2 and human CYP3A4.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020701

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Tags:575-04-2 Molecular Formula|575-04-2 MDL|575-04-2 SMILES|575-04-2 7-Methoxy-4-(trifluoromethyl)-2H-chromen-2-one