+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
642928-07-2,MFCD09752148
Catalog No.:AA00EDIQ

642928-07-2 | Homosildenafil

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
in stock  
$150.00   $105.00
- +
25mg
98%
in stock  
$442.00   $309.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00EDIQ
Chemical Name:
Homosildenafil
CAS Number:
642928-07-2
Molecular Formula:
C23H32N6O4S
Molecular Weight:
488.6030
MDL Number:
MFCD09752148
SMILES:
CCOc1ccc(cc1c1[nH]c(=O)c2c(n1)c(CCC)nn2C)S(=O)(=O)N1CCN(CC1)CC
Properties
Properties
 
Form:
Solid  
MP:
>190ºC (dec.)  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
854  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
1.8  

Downstream Synthesis Route

[1]LettersinOrganicChemistry,2011,vol.8,p.668-673

[2]AnalyticalChemistry,2018,vol.90,p.10765-10770

[3]AnalyticalChemistry,2018

[1]Acea,Jaume;Prez,Sandra;Gardinali,Piero;Abad,JosLuis;Eichhorn,Peter;Heuett,Nubia;Barcel,Dami[JournalofMassSpectrometry,2014,vol.49,#12,p.1279-1289]

[1]Sthalam,VinayKumar;Mahajan,Bhushan;Karra,PurushothamReddy;Singh,AjayK.;Pabbaraja,Srihari[RSCAdvances,2021,vol.12,#1,p.326-330]

[1]Sthalam,VinayKumar;Mahajan,Bhushan;Karra,PurushothamReddy;Singh,AjayK.;Pabbaraja,Srihari[RSCAdvances,2021,vol.12,#1,p.326-330]

[1]Sthalam,VinayKumar;Mahajan,Bhushan;Karra,PurushothamReddy;Singh,AjayK.;Pabbaraja,Srihari[RSCAdvances,2021,vol.12,#1,p.326-330]

Literature

Title: Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5).

Journal: Neurochemistry international 20041101

Title: Jackie D Corbin, et al. Vardenafil: Structural Basis for Higher Potency Over Sildenafil in Inhibiting cGMP-specific phosphodiesterase-5 (PDE5). Neurochem Int. 2004 Nov;45(6):859-63.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 642928-07-2
139756-22-2

139756-22-2

 139755-85-4

139755-85-4

 139755-95-6

139755-95-6

 171599-83-0

171599-83-0

 479073-82-0

479073-82-0

 268203-93-6

268203-93-6
Building Blocks
More >
Tags:642928-07-2 Molecular Formula|642928-07-2 MDL|642928-07-2 SMILES|642928-07-2 Homosildenafil
Catalog No.: AA00EDIQ
642928-07-2,MFCD09752148
642928-07-2 | Homosildenafil
Pack Size： 5mg
Purity： 98%
in stock
$150.00 $105.00
Pack Size： 25mg
Purity： 98%
in stock
$442.00 $309.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00EDIQ
Chemical Name: Homosildenafil
CAS Number: 642928-07-2
Molecular Formula: C23H32N6O4S
Molecular Weight: 488.6030
MDL Number: MFCD09752148
SMILES: CCOc1ccc(cc1c1[nH]c(=O)c2c(n1)c(CCC)nn2C)S(=O)(=O)N1CCN(CC1)CC
Properties
Form: Solid  
MP: >190ºC (dec.)  
Storage: -20 ℃;  
Complexity: 854  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 34  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 1.8  
Downstream Synthesis Route
5308-25-8    139756-22-2    642928-07-2 

[1]LettersinOrganicChemistry,2011,vol.8,p.668-673

[2]AnalyticalChemistry,2018,vol.90,p.10765-10770

[3]AnalyticalChemistry,2018

642928-07-2    1015447-61-6    1357931-55-5    372089-76-4    1675916-87-6    1675916-90-1    2196257-93-7    226956-39-4    1675917-13-1    139755-82-1 

[1]Acea,Jaume;Prez,Sandra;Gardinali,Piero;Abad,JosLuis;Eichhorn,Peter;Heuett,Nubia;Barcel,Dami[JournalofMassSpectrometry,2014,vol.49,#12,p.1279-1289]

613-69-4    642928-07-2 

[1]Sthalam,VinayKumar;Mahajan,Bhushan;Karra,PurushothamReddy;Singh,AjayK.;Pabbaraja,Srihari[RSCAdvances,2021,vol.12,#1,p.326-330]

139756-21-1    642928-07-2 

[1]Sthalam,VinayKumar;Mahajan,Bhushan;Karra,PurushothamReddy;Singh,AjayK.;Pabbaraja,Srihari[RSCAdvances,2021,vol.12,#1,p.326-330]

139756-02-8    642928-07-2 

[1]Sthalam,VinayKumar;Mahajan,Bhushan;Karra,PurushothamReddy;Singh,AjayK.;Pabbaraja,Srihari[RSCAdvances,2021,vol.12,#1,p.326-330]

Literature fold

Title: Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5).

Journal: Neurochemistry international20041101

Title: Jackie D Corbin, et al. Vardenafil: Structural Basis for Higher Potency Over Sildenafil in Inhibiting cGMP-specific phosphodiesterase-5 (PDE5). Neurochem Int. 2004 Nov;45(6):859-63.

Related Products of of 642928-07-2
139756-22-2
139756-22-2
139755-85-4
139755-85-4
139755-95-6
139755-95-6
171599-83-0
171599-83-0
479073-82-0
479073-82-0
268203-93-6
268203-93-6
Building Blocks More >
61855-47-8
61855-47-8
2,2,4-Trimethyl-1,2,3,4-tetrahydro-8-quinolinol
AA00EDQC | MFCD03410239
64679-65-8
64679-65-8
[(3-Methyl-1h-1,2,4-triazol-5-yl)thio]acetic acid
AA00EDUC | MFCD03247350
56464-51-8
56464-51-8
2-((4-Oxo-4-phenylbut-2-en-2-yl)amino)acetonitrile
AA00EDY3 | MFCD00102733
613656-97-6
613656-97-6
5-Bromo-7-chloro-1h-indole-2,3-dione
AA00EE31 | MFCD03618553
626604-80-6
626604-80-6
1H-Pyrrolo[2,3-b]pyridine-3-acetic acid, a-oxo-, ethyl ester
AA00EE6M | MFCD05256119
6331-61-9
6331-61-9
2-(4-Allyl-2-methoxyphenoxy)acetic acid
AA00EEA9 | MFCD00017594
57637-97-5
57637-97-5
N-ACETYLAMINOMETHYLPHOSPHONATE
AA00EEG7 | MFCD14105617
566-03-0
566-03-0
5-B-PREGNANE-3-A-21-DIOL-11-20-DIONE
AA00EEL9 | MFCD00051127
62574-23-6
62574-23-6
2-Methyl-3-(methylsulfanyl)propanoic acid
AA00EES0 | MFCD12823558
602-07-3
602-07-3
1-(2-(Dimethylamino)ethyl)-3,8-dimethoxychromeno[5,4,3-cde]chromene-5,10-dione
AA00EEYF | MFCD09837996
Submit
© 2017 AA BLOCKS, INC. All rights reserved.