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564-87-4,MFCD00148944
Catalog No.:AA00EEF8

564-87-4 | 11-cis Retinal

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2mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EEF8
Chemical Name:
11-cis Retinal
CAS Number:
564-87-4
Molecular Formula:
C20H28O
Molecular Weight:
284.4357
MDL Number:
MFCD00148944
SMILES:
O=C/C=C(/C=C\C=C(\C=C\C1=C(C)CCCC1(C)C)/C)\C
Properties
Computed Properties
 
Complexity:
522  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
4  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
6.2  

Literature

Title: Characterization of human short chain dehydrogenase/reductase SDR16C family members related to retinol dehydrogenase 10.

Journal: Chemico-biological interactions 20171001

Title: All-trans-retinal dimer formation alleviates the cytotoxicity of all-trans-retinal in human retinal pigment epithelial cells.

Journal: Toxicology 20160914

Title: The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20131201

Title: Aldo-keto reductases in retinoid metabolism: search for substrate specificity and inhibitor selectivity.

Journal: Chemico-biological interactions 20130225

Title: All-trans retinal mediates light-induced oxidation in single living rod photoreceptors.

Journal: Photochemistry and photobiology 20121101

Title: Retinal photodamage mediated by all-trans-retinal.

Journal: Photochemistry and photobiology 20121101

Title: Evidence for the Two-State-Two-Mode model in retinal protonated Schiff-bases from pump degenerate four-wave-mixing experiments.

Journal: Physical chemistry chemical physics : PCCP 20121028

Title: Ultrafast photochemistry of light-adapted and dark-adapted bacteriorhodopsin: effects of the initial retinal configuration.

Journal: The journal of physical chemistry. B 20120906

Title: Adoptive transfer of all-trans-retinal-induced regulatory T cells ameliorates experimental autoimmune arthritis in an interferon-gamma knockout model.

Journal: Autoimmunity 20120901

Title: A microparticle/hydrogel combination drug-delivery system for sustained release of retinoids.

Journal: Investigative ophthalmology & visual science 20120901

Title: Excitation energies of retinal chromophores: critical role of the structural model.

Journal: Physical chemistry chemical physics : PCCP 20120821

Title: Vitamin A metabolism in rod and cone visual cycles.

Journal: Annual review of nutrition 20120821

Title: Distinct loops in arrestin differentially regulate ligand binding within the GPCR opsin.

Journal: Nature communications 20120807

Title: Cultured Müller cells from mammals can synthesize and accumulate retinyl esters.

Journal: Experimental eye research 20120801

Title: Critical role of Asp227 in the photocycle of proteorhodopsin.

Journal: Biochemistry 20120717

Title: Photochemical properties of mammalian melanopsin.

Journal: Biochemistry 20120710

Title: Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy.

Journal: Biochimica et biophysica acta 20120701

Title: Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.

Journal: The Journal of biological chemistry 20120622

Title: Melanopsin is highly resistant to light and chemical bleaching in vivo.

Journal: The Journal of biological chemistry 20120615

Title: The exciton origin of the visible circular dichroism spectrum of bacteriorhodopsin.

Journal: The journal of physical chemistry. B 20120614

Title: An S-opsin knock-in mouse (F81Y) reveals a role for the native ligand 11-cis-retinal in cone opsin biosynthesis.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120606

Title: Tuning the primary reaction of channelrhodopsin-2 by imidazole, pH, and site-specific mutations.

Journal: Biophysical journal 20120606

Title: Determination of vitamin A and its metabolites in rat testis: possible involvement of vitamin A in testicular toxicity caused by molinate.

Journal: Bulletin of environmental contamination and toxicology 20120601

Title: Rapid release of retinal from a cone visual pigment following photoactivation.

Journal: Biochemistry 20120522

Title: Vertebrate ancient opsin photopigment spectra and the avian photoperiodic response.

Journal: Biology letters 20120423

Title: Increased blood oxidative stress in experimental menopause rat model: the effects of vitamin A low-dose supplementation upon antioxidant status in bilateral ovariectomized rats.

Journal: Fundamental & clinical pharmacology 20120401

Title: Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state.

Journal: Biochimica et biophysica acta 20120401

Title: Enhancement of retinal production by supplementing the surfactant Span 80 using metabolically engineered Escherichia coli.

Journal: Journal of bioscience and bioengineering 20120401

Title: Insights into the activation mechanism of the visual receptor rhodopsin.

Journal: Biochemical Society transactions 20120401

Title: New therapeutic targets in dermatoporosis.

Journal: The journal of nutrition, health & aging 20120401

Title: Insight into molecular pathways of retinal metabolism, associated with vitellogenesis in zebrafish.

Journal: American journal of physiology. Endocrinology and metabolism 20120315

Title: Expression and activity of alcohol and aldehyde dehydrogenases in melanoma cells and in melanocytes.

Journal: Journal of cellular biochemistry 20120301

Title: The bisretinoids of retinal pigment epithelium.

Journal: Progress in retinal and eye research 20120301

Title: The effect of protein environment on photoexcitation properties of retinal.

Journal: The journal of physical chemistry. B 20120223

Title: Time-resolved spectroscopy of ultrafast photoisomerization of octopus rhodopsin under photoexcitation.

Journal: The journal of physical chemistry. B 20120216

Title: Crystal structure of the channelrhodopsin light-gated cation channel.

Journal: Nature 20120216

Title: Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration.

Journal: The Journal of biological chemistry 20120210

Title: Light-sensitive coupling of rhodopsin and melanopsin to G(i/o) and G(q) signal transduction in Caenorhabditis elegans.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120201

Title: Primary amines protect against retinal degeneration in mouse models of retinopathies.

Journal: Nature chemical biology 20120201

Title: Understanding rhodopsin mutations linked to the retinitis pigmentosa disease: a QM/MM and DFT/MRCI study.

Journal: The journal of physical chemistry. B 20120126

Title: Population branching in the conical intersection of the retinal chromophore revealed by multipulse ultrafast optical spectroscopy.

Journal: Journal of the American Chemical Society 20120118

Title: Chemistry and biology of vision.

Journal: The Journal of biological chemistry 20120113

Title: Rod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approaches.

Journal: The Journal of biological chemistry 20120113

Title: Key enzymes of the retinoid (visual) cycle in vertebrate retina.

Journal: Biochimica et biophysica acta 20120101

Title: Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids.

Journal: Biochimica et biophysica acta 20120101

Title: The mechanism of fenretinide (4-HPR) inhibition of β-carotene monooxygenase 1. New suspect for the visual side effects of fenretinide.

Journal: Advances in experimental medicine and biology 20120101

Title: Molecular clues to Bothnia-type retinal dystrophy.

Journal: Advances in experimental medicine and biology 20120101

Title: Acute systemic 11-cis-retinal intervention improves abnormal outer retinal ion channel closure in diabetic mice.

Journal: Molecular vision 20120101

Title: Differential expression of the demosponge (Suberites domuncula) carotenoid oxygenases in response to light: protection mechanism against the self-produced toxic protein (Suberitine).

Journal: Marine drugs 20120101

Title: [Photosensing by membrane-embedded receptors and its application for the life scientists].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101

Title: Retinol metabolism in the mollusk Osilinus lineatus indicates an ancient origin for retinyl ester storage capacity.

Journal: PloS one 20120101

Title: Cytotoxicity of all-trans-retinal increases upon photodegradation.

Journal: Photochemistry and photobiology 20120101

Title: Comparative analysis of the heptahelical transmembrane bundles of G protein-coupled receptors.

Journal: PloS one 20120101

Title: M-opsin protein degradation is inhibited by MG-132 in Rpe65⁻/⁻ retinal explant culture.

Journal: Molecular vision 20120101

Title: A novel source of methylglyoxal and glyoxal in retina: implications for age-related macular degeneration.

Journal: PloS one 20120101

Title: Retinal attenuates inflammatory arthritis by reciprocal regulation of IL-17-producing T cells and Foxp3(+) regulatory T cells and the inhibition of osteoclastogenesis.

Journal: Immunology letters 20120101

Title: Probing a polar cluster in the retinal binding pocket of bacteriorhodopsin by a chemical design approach.

Journal: PloS one 20120101

Title: The hepatic Raldh1 expression is elevated in Zucker fatty rats and its over-expression introduced the retinal-induced Srebp-1c expression in INS-1 cells.

Journal: PloS one 20120101

Title: Light-induced damage to the retina: current understanding of the mechanisms and unresolved questions: a symposium-in-print.

Journal: Photochemistry and photobiology 20120101

Title: Quantum mechanical/molecular mechanical structure, enantioselectivity, and spectroscopy of hydroxyretinals and insights into the evolution of color vision in small white butterflies.

Journal: The journal of physical chemistry. B 20111229

Title: Vibrational analysis of excited and ground electronic states of all-trans retinal protonated Schiff-bases.

Journal: Physical chemistry chemical physics : PCCP 20111228

Title: Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.

Journal: The Biochemical journal 20111215

Title: Vertebrate ancient-long opsin has molecular properties intermediate between those of vertebrate and invertebrate visual pigments.

Journal: Biochemistry 20111206

Title: Expression of salinarum halorhodopsin in Escherichia coli cells: solubilization in the presence of retinal yields the natural state.

Journal: Biochimica et biophysica acta 20111201

Title: Why 11-cis-retinal? Why not 7-cis-, 9-cis-, or 13-cis-retinal in the eye?

Journal: Journal of the American Chemical Society 20111130

Title: UVA phototransduction drives early melanin synthesis in human melanocytes.

Journal: Current biology : CB 20111122

Title: Molecular mechanisms of disease for mutations at Gly-90 in rhodopsin.

Journal: The Journal of biological chemistry 20111118

Title: Human retinal pigment epithelium cells as functional models for the RPE in vivo.

Journal: Investigative ophthalmology & visual science 20111101

Title: A novel bisretinoid of retina is an adduct on glycerophosphoethanolamine.

Journal: Investigative ophthalmology & visual science 20111101

Title: Light activation of the isomerization and deprotonation of the protonated Schiff base retinal.

Journal: Journal of molecular modeling 20111001

Title: Uncoupling of retinoic acid signaling from tailbud development before termination of body axis extension.

Journal: Genesis (New York, N.Y. : 2000) 20111001

Title: Time-resolved WAXS reveals accelerated conformational changes in iodoretinal-substituted proteorhodopsin.

Journal: Biophysical journal 20110921

Title: Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05).

Journal: Journal of neuro-oncology 20110901

Title: Alkylated hydroxylamine derivatives eliminate peripheral retinylidene Schiff bases but cannot enter the retinal binding pocket of light-activated rhodopsin.

Journal: Biochemistry 20110823

Title: An amino acid residue (S201) in the retinal binding pocket regulates the photoreaction pathway of phoborhodopsin.

Journal: Biochemistry 20110823

Title: H-bond network around retinal regulates the evolution of ultraviolet and violet vision.

Journal: ACS chemical biology 20110819

Title: Thermal properties of rhodopsin: insight into the molecular mechanism of dim-light vision.

Journal: The Journal of biological chemistry 20110805

Title: Steric and electronic influences on the torsional energy landscape of retinal.

Journal: Biophysical journal 20110803

Title: Evidence from Chlamydomonas on the photoactivation of rhodopsins without isomerization of their chromophore.

Journal: Chemistry & biology 20110624

Title: An intramolecular charge transfer state of carbonyl carotenoids: implications for excited state dynamics of apo-carotenals and retinal.

Journal: Physical chemistry chemical physics : PCCP 20110614

Title: Structural characteristics around the β-ionone ring of the retinal chromophore in Salinibacter sensory rhodopsin I.

Journal: Biochemistry 20110607

Title: Reduction of the virtual space for coupled-cluster excitation energies of large molecules and embedded systems.

Journal: The Journal of chemical physics 20110607

Title: Retinaldehyde/hyaluronic acid fragments: a synergistic association for the management of skin aging.

Journal: Journal of cosmetic dermatology 20110601

Title: Human and rodent aldo-keto reductases from the AKR1B subfamily and their specificity with retinaldehyde.

Journal: Chemico-biological interactions 20110530

Title: Role of bulk water in hydrolysis of the rhodopsin chromophore.

Journal: The Journal of biological chemistry 20110527

Title: Conserved Tyr223(5.58) plays different roles in the activation and G-protein interaction of rhodopsin.

Journal: Journal of the American Chemical Society 20110511

Title: Macular degeneration: a possible biochemical mechanism.

Journal: Medical hypotheses 20110501

Title: Binding affinities of CRBPI and CRBPII for 9-cis-retinoids.

Journal: Biochimica et biophysica acta 20110501

Title: Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice.

Journal: The Journal of biological chemistry 20110429

Title: Retinal and retinol are potential regulators of gene expression in the keratinocyte cell line HaCaT.

Journal: Experimental dermatology 20110401

Title: Light prevents exogenous 11-cis retinal from maintaining cone photoreceptors in chromophore-deficient mice.

Journal: Investigative ophthalmology & visual science 20110401

Title: Spectral tuning in sensory rhodopsin I from Salinibacter ruber.

Journal: The Journal of biological chemistry 20110401

Title: The structural basis of agonist-induced activation in constitutively active rhodopsin.

Journal: Nature 20110331

Title: Crystal structure of metarhodopsin II.

Journal: Nature 20110331

Title: Cyclopropyl and isopropyl derivatives of 11-cis and 9-cis retinals at C-9 and C-13: subtle steric differences with major effects on ligand efficacy in rhodopsin.

Journal: Journal of natural products 20110325

Title: Probing human red cone opsin activity with retinal analogues.

Journal: Journal of natural products 20110325

Title: Retinoids synergized with insulin to induce Srebp-1c expression and activated its promoter via the two liver X receptor binding sites that mediate insulin action.

Journal: Biochemical and biophysical research communications 20110311

Title: Product formation in rhodopsin by fast hydrogen motions.

Journal: Physical chemistry chemical physics : PCCP 20110307

Title: Retinal dynamics underlie its switch from inverse agonist to agonist during rhodopsin activation.

Journal: Nature structural & molecular biology 20110301

Title: Coherent control of the isomerization of retinal in bacteriorhodopsin in the high intensity regime.

Journal: The Journal of chemical physics 20110227

Title: Large-scale production of a disulfide-stabilized constitutively active mutant opsin.

Journal: Protein expression and purification 20110201

Title: Photochemistry of a putative new class of sensory rhodopsin (SRIII) coded by xop2 of Haloarcular marismortui.

Journal: Journal of photochemistry and photobiology. B, Biology 20110110

Title: Second-harmonic generation imaging of membrane potential with retinal analogues.

Journal: Biophysical journal 20110105

Title: Milk, revealed 'silent' chemistry: new mode of cycloretinal synthesis.

Journal: Molecular bioSystems 20110101

Title: Water pathways in the bacteriorhodopsin proton pump.

Journal: The Journal of membrane biology 20110101

Title: Retinal release from opsin in molecular dynamics simulations.

Journal: Journal of molecular recognition : JMR 20110101

Title: Regulation of gene expression by retinoids.

Journal: Current medicinal chemistry 20110101

Title: Altered expression of β-galactosidase-1-like protein 3 (Glb1l3) in the retinal pigment epithelium (RPE)-specific 65-kDa protein knock-out mouse model of Leber's congenital amaurosis.

Journal: Molecular vision 20110101

Title: Effects of mutations of Lys41 and Asp102 of bacteriorhodopsin.

Journal: Bioscience, biotechnology, and biochemistry 20110101

Title: Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system.

Journal: Microbial cell factories 20110101

Title: UV-sensitive photoreceptor protein OPN5 in humans and mice.

Journal: PloS one 20110101

Title: High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function.

Journal: Diabetes 20101201

Title: Exonic SINE insertion in STK38L causes canine early retinal degeneration (erd).

Journal: Genomics 20101201

Title: QM/MM study of dehydro and dihydro β-ionone retinal analogues in squid and bovine rhodopsins: implications for vision in salamander rhodopsin.

Journal: Journal of the American Chemical Society 20101117

Title: The contribution of a covalently bound cofactor to the folding and thermodynamic stability of an integral membrane protein.

Journal: Journal of molecular biology 20101105

Title: Parallel visual cycles in the zebrafish retina.

Journal: Progress in retinal and eye research 20101101

Title: Effective and sustained delivery of hydrophobic retinoids to photoreceptors.

Journal: Investigative ophthalmology & visual science 20101101

Title: Hydroxylamine as a thermal destabiliser of bacteriorhodopsin.

Journal: European biophysics journal : EBJ 20101101

Title: Improvement of visual performance with intravitreal administration of 9-cis-retinal in Rpe65-mutant dogs.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20101101

Title: Functional analysis of the second extracellular loop of rhodopsin by characterizing split variants.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20101101

Title: Blind dogs that can see: pharmacological treatment of Leber congenital amaurosis caused by a defective visual cycle.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20101101

Title: [Evaluation of factors associated with variability in retinal nerve fiber layer thickness in myopic juveniles aged 7-18 years].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20101101

Title: Coupling of retinal, protein, and water dynamics in squid rhodopsin.

Journal: Biophysical journal 20101006

Title: Biotransformation of carotenoids to retinal by carotenoid 15,15'-oxygenase.

Journal: Applied microbiology and biotechnology 20101001

Title: Retinobenzaldehydes as proper-trafficking inducers of folding-defective P23H rhodopsin mutant responsible for retinitis pigmentosa.

Journal: Bioorganic & medicinal chemistry 20101001

Title: Physical chemistry: Seaming is believing.

Journal: Nature 20100923

Title: Conical intersection dynamics of the primary photoisomerization event in vision.

Journal: Nature 20100923

Title: Retinoid storage in the egg of reptiles and birds.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20100901

Title: Interpretations of fundus autofluorescence from studies of the bisretinoids of the retina.

Journal: Investigative ophthalmology & visual science 20100901

Title: Lighting a candle in the dark: advances in genetics and gene therapy of recessive retinal dystrophies.

Journal: The Journal of clinical investigation 20100901

Title: Topical retinoids induce β-defensin 3 expression in mouse skin.

Journal: International journal of dermatology 20100901

Title: The efficacy of topical drugs in treatment of noninflammatory acne vulgaris.

Journal: Georgian medical news 20100901

Title: Nonadiabatic ab initio dynamics of a model protonated Schiff base of 9-cis retinal.

Journal: The journal of physical chemistry. A 20100819

Title: Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis.

Journal: FEBS letters 20100716

Title: Retinal production from beta-carotene by beta-carotene 15,15'-dioxygenase from an unculturable marine bacterium.

Journal: Biotechnology letters 20100701

Title: Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein.

Journal: Journal of lipid research 20100701

Title: Interaction of extracellular domain 2 of the human retina-specific ATP-binding cassette transporter (ABCA4) with all-trans-retinal.

Journal: The Journal of biological chemistry 20100618

Title: Binding of anions to proteorhodopsin affects the Asp97 pK(a).

Journal: Biochemistry 20100601

Title: Retinoids for treatment of retinal diseases.

Journal: Trends in pharmacological sciences 20100601

Title: Acne rosacea: effectiveness of 532 nm laser on the cosmetic appearance of the skin.

Journal: Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 20100601

Title: Putative active states of a prototypic g-protein-coupled receptor from biased molecular dynamics.

Journal: Biophysical journal 20100519

Title: Studies of the ground and excited-state surfaces of the retinal chromophore using CAM-B3LYP.

Journal: The journal of physical chemistry. B 20100429

Title: Protein fluctuations as the possible origin of the thermal activation of rod photoreceptors in the dark.

Journal: Journal of the American Chemical Society 20100428

Title: Low-temperature FTIR study of Gloeobacter rhodopsin: presence of strongly hydrogen-bonded water and long-range structural protein perturbation upon retinal photoisomerization.

Journal: Biochemistry 20100420

Title: Sequential rearrangement of interhelical networks upon rhodopsin activation in membranes: the Meta II(a) conformational substate.

Journal: Journal of the American Chemical Society 20100407

Title: Coherent ultrafast torsional motion and isomerization of a biomimetic dipolar photoswitch.

Journal: Physical chemistry chemical physics : PCCP 20100407

Title: Induction of uncoupling protein-1 in mouse embryonic fibroblast-derived adipocytes by retinoic acid.

Journal: Obesity (Silver Spring, Md.) 20100401

Title: Single doses of all-trans-N-retinylacetamide slow down the ERG amplitude recovery after bleaching in rats.

Journal: Documenta ophthalmologica. Advances in ophthalmology 20100401

Title: Degenerate two-photon absorption in all-trans retinal: nonlinear spectrum and theoretical calculations.

Journal: The journal of physical chemistry. A 20100318

Title: Regulation of photoreceptor gene expression by the retinal homeobox (Rx) gene product.

Journal: Developmental biology 20100315

Title: Synthesis and use of stable isotope enriched retinals in the field of vitamin A.

Journal: Molecules (Basel, Switzerland) 20100315

Title: Covalent bond between ligand and receptor required for efficient activation in rhodopsin.

Journal: The Journal of biological chemistry 20100312

Title: A pivot between helices V and VI near the retinal-binding site is necessary for activation in rhodopsins.

Journal: The Journal of biological chemistry 20100305

Title: {beta}-Apocarotenoids do not significantly activate retinoic acid receptors {alpha} or {beta}.

Journal: Experimental biology and medicine (Maywood, N.J.) 20100301

Title: Molecular mechanisms of rhodopsin retinitis pigmentosa and the efficacy of pharmacological rescue.

Journal: Journal of molecular biology 20100205

Title: A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors.

Journal: The Journal of biological chemistry 20100205

Title: Phospholipid meets all-trans-retinal: the making of RPE bisretinoids.

Journal: Journal of lipid research 20100201

Title: Retinal dynamics during light activation of rhodopsin revealed by solid-state NMR spectroscopy.

Journal: Biochimica et biophysica acta 20100201

Title: NinaB is essential for Drosophila vision but induces retinal degeneration in opsin-deficient photoreceptors.

Journal: The Journal of biological chemistry 20100115

Title: Rpe65 isomerase associates with membranes through an electrostatic interaction with acidic phospholipid headgroups.

Journal: The Journal of biological chemistry 20100108

Title: Dependence of photochemical reactivity of the all-trans retinal protonated Schiff base on the solvent and the excitation wavelength.

Journal: Photochemistry and photobiology 20100101

Title: The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier--implications for the pathogenesis of diabetic retinopathy.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Structure and activation of the visual pigment rhodopsin.

Journal: Annual review of biophysics 20100101

Title: Femtosecond formation dynamics of primary photoproducts of visual pigment rhodopsin.

Journal: Biochemistry. Biokhimiia 20100101

Title: Cosmeceuticals: the evidence behind the retinoids.

Journal: Aesthetic surgery journal 20100101

Title: Comparison of A2E cytotoxicity and phototoxicity with all-trans-retinal in human retinal pigment epithelial cells.

Journal: Photochemistry and photobiology 20100101

Title: Quantification of endogenous retinoids.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: In vitro assays of rod and cone opsin activity: retinoid analogs as agonists and inverse agonists.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Physiological studies of the interaction between opsin and chromophore in rod and cone visual pigments.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Binding of retinoids to ABCA4, the photoreceptor ABC transporter associated with Stargardt macular degeneration.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Molecular biology and analytical chemistry methods used to probe the retinoid cycle.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Photoreceptor structure and function is maintained in organotypic cultures of mouse retinas.

Journal: Molecular vision 20100101

Title: Bisretinoids of RPE lipofuscin: trigger for complement activation in age-related macular degeneration.

Journal: Advances in experimental medicine and biology 20100101

Title: Synergistic effect of hyaluronate fragments in retinaldehyde-induced skin hyperplasia which is a Cd44-dependent phenomenon.

Journal: PloS one 20100101

Title: Just in the nick of time: targeting acute versus chronic disease.

Journal: Oxidative medicine and cellular longevity 20100101

Title: Reaction pathways of photoexcited retinal in proteorhodopsin studied by pump-dump-probe spectroscopy.

Journal: The journal of physical chemistry. B 20091217

Title: Fluoro derivatives of retinal illuminate the decisive role of the C(12)-H element in photoisomerization and rhodopsin activation.

Journal: Journal of the American Chemical Society 20091216

Title: Retinal-protein interactions in halorhodopsin from Natronomonas pharaonis: binding and retinal thermal isomerization catalysis.

Journal: Journal of molecular biology 20091204

Title: Cortical dynamics of navigation and steering in natural scenes: Motion-based object segmentation, heading, and obstacle avoidance.

Journal: Neural networks : the official journal of the International Neural Network Society 20091201

Title: Elucidating the exact role of engineered CRABPII residues for the formation of a retinal protonated Schiff base.

Journal: Proteins 20091201

Title: Kinetic characterization of recombinant mouse retinal dehydrogenase types 3 and 4 for retinal substrates.

Journal: Biochimica et biophysica acta 20091201

Title: Calnexin improves the folding efficiency of mutant rhodopsin in the presence of pharmacological chaperone 11-cis-retinal.

Journal: The Journal of biological chemistry 20091127

Title: Reconstitution of Gloeobacter violaceus rhodopsin with a light-harvesting carotenoid antenna.

Journal: Biochemistry 20091124

Title: Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina.

Journal: Investigative ophthalmology & visual science 20091101

Title: Color tuning in short wavelength-sensitive human and mouse visual pigments: ab initio quantum mechanics/molecular mechanics studies.

Journal: The journal of physical chemistry. A 20091029

Title: Is the photoinduced isomerization in retinal protonated Schiff bases a single- or double-torsional process?

Journal: The journal of physical chemistry. A 20091029

Title: 6-s-cis Conformation and polar binding pocket of the retinal chromophore in the photoactivated state of rhodopsin.

Journal: Journal of the American Chemical Society 20091028

Title: Evolution and the origin of the visual retinoid cycle in vertebrates.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20091012

Title: Evolution of vertebrate retinal photoreception.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20091012

Title: The evolution of early vertebrate photoreceptors.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20091012

Title: Cone outer segment morphology and cone function in the Rpe65-/- Nrl-/- mouse retina are amenable to retinoid replacement.

Journal: Investigative ophthalmology & visual science 20091001

Title: Identification and characterization of retinoid-active short-chain dehydrogenases/reductases in Drosophila melanogaster.

Journal: Biochimica et biophysica acta 20091001

Title: Ustilago maydis accumulates beta-carotene at levels determined by a retinal-forming carotenoid oxygenase.

Journal: Fungal genetics and biology : FG & B 20091001

Title: Picosecond time-resolved ultraviolet resonance Raman spectroscopy of bacteriorhodopsin: primary protein response to the photoisomerization of retinal.

Journal: The journal of physical chemistry. B 20090903

Title: Retinal-salinixanthin interactions in xanthorhodopsin: [corrected] a circular dichroism (CD) spectroscopy study with artificial pigments.

Journal: Biochemistry 20090901

Title: Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.

Journal: Nature chemical biology 20090901

Title: Acceleration of the Z to E photoisomerization of penta-2,4-dieniminium by hydrogen out-of-plane motion: theoretical study on a model system of retinal protonated Schiff base.

Journal: Physical chemistry chemical physics : PCCP 20090814

Title: Rlbp1 promoter drives robust Müller glial GFP expression in transgenic mice.

Journal: Investigative ophthalmology & visual science 20090801

Title: Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease.

Journal: The Journal of biological chemistry 20090724

Title: Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design.

Journal: Journal of medicinal chemistry 20090723

Title: X-ray structure breakthroughs in the GPCR transmembrane region.

Journal: Biochemical pharmacology 20090701

Title: Thermal decay of rhodopsin: role of hydrogen bonds in thermal isomerization of 11-cis retinal in the binding site and hydrolysis of protonated Schiff base.

Journal: Journal of the American Chemical Society 20090701

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Title: Night blindness and the mechanism of constitutive signaling of mutant G90D rhodopsin.

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Title: Reprogramming progeny cells of embryonic RPE to produce photoreceptors: development of advanced photoreceptor traits under the induction of neuroD.

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Title: The molecular structure of a curl-shaped retinal isomer.

Journal: Journal of molecular modeling 20080801

Title: Retinal models: comparison of electronic absorption spectra in the gas phase and in methanol solution.

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Title: Kinetic analysis of human enzyme RDH10 defines the characteristics of a physiologically relevant retinol dehydrogenase.

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Title: 11-cis- and all-trans-retinols can activate rod opsin: rational design of the visual cycle.

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Title: Retinal pigment epithelium-retinal G protein receptor-opsin mediates light-dependent translocation of all-trans-retinyl esters for synthesis of visual chromophore in retinal pigment epithelial cells.

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Journal: Nature 20080710

Title: HPLC/UV quantitation of retinal, retinol, and retinyl esters in serum and tissues.

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Title: Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1.

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Title: Rpe65-/- and Lrat-/- mice: comparable models of leber congenital amaurosis.

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Title: Effect of lipid peroxidation products on the activity of human retinol dehydrogenase 12 (RDH12) and retinoid metabolism.

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Title: Screening and characterization of proteorhodopsin color-tuning mutations in Escherichia coli with endogenous retinal synthesis.

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Title: Crystal structure of squid rhodopsin.

Journal: Nature 20080515

Title: Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina.

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Title: Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080409

Title: Metabolism and biological activities of topical 4-oxoretinoids in mouse skin.

Journal: The Journal of investigative dermatology 20080401

Title: Nrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments.

Journal: Investigative ophthalmology & visual science 20080301

Title: Rhodopsin and 9-demethyl-retinal analog: effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors.

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Journal: Experimental eye research 20080201

Title: Light damaging action of all-trans-retinal and its derivatives on rhodopsin molecules in the photoreceptor membrane.

Journal: Biochemistry. Biokhimiia 20080201

Title: R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal.

Journal: Human molecular genetics 20080115

Title: Optimized formation of detergent micelles of beta-carotene and retinal production using recombinant human beta,beta-carotene 15,15'-monooxygenase.

Journal: Biotechnology progress 20080101

Title: Ocular biometry in preterm infants: implications for estimation of retinal illuminance.

Journal: Investigative ophthalmology & visual science 20080101

Title: A convenient and stereoselective synthesis of 11Z-3,4-didehydroretinal by Horner-Emmons reaction using diphenyl phosphonate.

Journal: Chemical & pharmaceutical bulletin 20080101

Title: A2E, a pigment of RPE lipofuscin, is generated from the precursor, A2PE by a lysosomal enzyme activity.

Journal: Advances in experimental medicine and biology 20080101

Title: Alpha-retinals as rhodopsin chromophores--preference for the 9-Z configuration and partial agonist activity.

Journal: Photochemistry and photobiology 20080101

Title: Rhodopsin regeneration is accelerated via noncovalent 11-cis retinal-opsin complex--a role of retinal binding pocket of opsin.

Journal: Photochemistry and photobiology 20080101

Title: Chromophore interaction in xanthorhodopsin--retinal dependence of salinixanthin binding.

Journal: Photochemistry and photobiology 20080101

Title: Activity switches of rhodopsin.

Journal: Photochemistry and photobiology 20080101

Title: Xanthorhodopsin: a bacteriorhodopsin-like proton pump with a carotenoid antenna.

Journal: Biochimica et biophysica acta 20080101

Title: [Synthesis of spyropyran derivatives of retinal and study of their interaction with bacterioopsin from Halobacterium salinarum].

Journal: Bioorganicheskaia khimiia 20080101

Title: Impairment of A2-rhodopsin regeneration induced by visible (blue) light.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20080101

Title: Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20071226

Title: Overproduction of bioactive retinoic acid in cells expressing disease-associated mutants of retinol dehydrogenase 12.

Journal: The Journal of biological chemistry 20071207

Title: Solid-state 2H NMR spectroscopy of retinal proteins in aligned membranes.

Journal: Biochimica et biophysica acta 20071201

Title: Chromophore switch from 11-cis-dehydroretinal (A2) to 11-cis-retinal (A1) decreases dark noise in salamander red rods.

Journal: The Journal of physiology 20071115

Title: Mechanism of spectral tuning in green-absorbing proteorhodopsin.

Journal: Biochemistry 20071106

Title: The dual substrate specificity of aldehyde oxidase 1 for retinal and acetaldehyde and its role in ABCA1 mediated efflux.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20071101

Title: [Vitamin A, in the eye of the fat].

Journal: Medecine sciences : M/S 20071101

Title: 7,8-dihydro retinals outperform the native retinals in conferring photosensitivity to visual opsin.

Journal: Journal of the American Chemical Society 20071031

Title: An opsin shift in rhodopsin: retinal S0-S1 excitation in protein, in solution, and in the gas phase.

Journal: Journal of the American Chemical Society 20071031

Title: CNDOL: A fast and reliable method for the calculation of electronic properties of very large systems. Applications to retinal binding pocket in rhodopsin and gas phase porphine.

Journal: The Journal of chemical physics 20071014

Title: Interpreting ion fluxes to channel arrays in monolayers.

Journal: Langmuir : the ACS journal of surfaces and colloids 20071009

Title: Effective production of retinal from beta-carotene using recombinant mouse beta-carotene 15,15'-monooxygenase.

Journal: Applied microbiology and biotechnology 20071001

Title: Evidence for RPE65-independent vision in the cone-dominated zebrafish retina.

Journal: The European journal of neuroscience 20071001

Title: Optical switches and triggers for the manipulation of ion channels and pores.

Journal: Molecular bioSystems 20071001

Title: Dynamic structure of retinylidene ligand of rhodopsin probed by molecular simulations.

Journal: Journal of molecular biology 20070928

Title: Structural analysis and dynamics of retinal chromophore in dark and meta I states of rhodopsin from 2H NMR of aligned membranes.

Journal: Journal of molecular biology 20070907

Title: The twisted C11=C12 bond of the rhodopsin chromophore--a photochemical hot spot.

Journal: Journal of the American Chemical Society 20070905

Title: IgG antibody patterns in aqueous humor of patients with primary open angle glaucoma and pseudoexfoliation glaucoma.

Journal: Molecular vision 20070905

Title: Dark rearing rescues P23H rhodopsin-induced retinal degeneration in a transgenic Xenopus laevis model of retinitis pigmentosa: a chromophore-dependent mechanism characterized by production of N-terminally truncated mutant rhodopsin.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070822

Title: Compensated adiabatic inversion pulses: broadband INEPT and HSQC.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20070801

Title: Comment on 'Coherent control of retinal isomerization in bacteriorhodopsin'.

Journal: Science (New York, N.Y.) 20070727

Title: Analysis of the NADH-dependent retinaldehyde reductase activity of amphioxus retinol dehydrogenase enzymes enhances our understanding of the evolution of the retinol dehydrogenase family.

Journal: The FEBS journal 20070701

Title: [The change of the level of the vascular endothelial growth factor in aqueous humor of patients with neovascular glaucoma before and after anterior retinal cryotherapy].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20070701

Title: Electron microscopy: molecular freeze frame.

Journal: Nature nanotechnology 20070701

Title: Imaging the dynamic behaviour of individual retinal chromophores confined inside carbon nanotubes.

Journal: Nature nanotechnology 20070701

Title: Direct observation of protein motion during the photochemical reaction cycle of bacteriorhodopsin.

Journal: Langmuir : the ACS journal of surfaces and colloids 20070619

Title: Cantilever-based sensor for the detection of different chromophore isomers.

Journal: Analytical chemistry 20070615

Title: Upregulation of thioredoxin system via Nrf2-antioxidant responsive element pathway in adaptive-retinal neuroprotection in vivo and in vitro.

Journal: Free radical biology & medicine 20070615

Title: Coupled-cluster studies of the lowest excited states of the 11-cis-retinal chromophore.

Journal: Physical chemistry chemical physics : PCCP 20070614

Title: Chromophore channeling in the G-protein coupled receptor rhodopsin.

Journal: Journal of the American Chemical Society 20070606

Title: Androgen regulation of aldehyde dehydrogenase 1A3 (ALDH1A3) in the androgen-responsive human prostate cancer cell line LNCaP.

Journal: Experimental biology and medicine (Maywood, N.J.) 20070601

Title: Retinaldehyde represses adipogenesis and diet-induced obesity.

Journal: Nature medicine 20070601

Title: Retinaldehyde: more than meets the eye.

Journal: Nature medicine 20070601

Title: The effects of copper and benzo[a]pyrene on retinoids and reproduction in zebrafish.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070531

Title: Probing the sub-microsecond photodissociation dynamics in gas-phase retinal chromophores.

Journal: The journal of physical chemistry. A 20070531

Title: Photoisomerization efficiency in UV-absorbing visual pigments: protein-directed isomerization of an unprotonated retinal Schiff base.

Journal: Biochemistry 20070529

Title: Protein design: reengineering cellular retinoic acid binding protein II into a rhodopsin protein mimic.

Journal: Journal of the American Chemical Society 20070516

Title: FTIR study of the retinal Schiff base and internal water molecules of proteorhodopsin.

Journal: Biochemistry 20070508

Title: Beyond retinotopic mapping: the spatial representation of objects in the human lateral occipital complex.

Journal: Cerebral cortex (New York, N.Y. : 1991) 20070501

Title: Cellular sites of Drosophila NinaB and NinaD activity in vitamin A metabolism.

Journal: Molecular and cellular neurosciences 20070501

Title: Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections.

Journal: Nature neuroscience 20070501

Title: Dissection of the pathway required for generation of vitamin A and for Drosophila phototransduction.

Journal: The Journal of cell biology 20070423

Title: Photochemistry of visual pigment chromophore models by ab initio molecular dynamics.

Journal: The journal of physical chemistry. B 20070412

Title: Deactivation and proton transfer in light-induced metarhodopsin II/metarhodopsin III conversion: a time-resolved fourier transform infrared spectroscopic study.

Journal: The Journal of biological chemistry 20070406

Title: Retinal biosynthesis in fungi: characterization of the carotenoid oxygenase CarX from Fusarium fujikuroi.

Journal: Eukaryotic cell 20070401

Title: Interactions of human serum albumin with retinoic acid, retinal and retinyl acetate.

Journal: Biochemical pharmacology 20070315

Title: Quantification of sudden light-induced polarization in bacteriorhodopsin by optical rectification.

Journal: The journal of physical chemistry. B 20070315

Title: Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1).

Journal: Biochimie 20070301

Title: How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.

Journal: Proteins 20070215

Title: Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration.

Journal: Biochemical pharmacology 20070215

Title: Solid-state NMR studies of two backbone conformations at Tyr185 as a function of retinal configurations in the dark, light, and pressure adapted bacteriorhodopsins.

Journal: Journal of the American Chemical Society 20070207

Title: Structural changes in the L photointermediate of bacteriorhodopsin.

Journal: Journal of molecular biology 20070202

Title: G-protein-coupled receptor signalling through protein networks.

Journal: Biochemical Society transactions 20070201

Title: RPE65 is essential for the function of cone photoreceptors in NRL-deficient mice.

Journal: Investigative ophthalmology & visual science 20070201

Title: Sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo.

Journal: The Journal of biological chemistry 20070112

Title: The role of the beta-ionone ring in the photochemical reaction of rhodopsin.

Journal: The journal of physical chemistry. A 20070111

Title: Photoisomerization in proteorhodopsin mutant D97N.

Journal: Photochemistry and photobiology 20070101

Title: Tryptophan 171 in Pharaonis phoborhodopsin (sensory rhodopsin II) interacts with the chromophore retinal and its substitution with alanine or threonine slowed down the decay of M- and O-intermediate.

Journal: Photochemistry and photobiology 20070101

Title: Pressure-induced isomerization of retinal on bacteriorhodopsin as disclosed by fast magic angle spinning NMR.

Journal: Photochemistry and photobiology 20070101

Title: Sub-5-fs real-time spectroscopy of transition states in bacteriorhodopsin during retinal isomerization.

Journal: Photochemistry and photobiology 20070101

Title: Light induces programmed cell death by activating multiple independent proteases in a cone photoreceptor cell line.

Journal: Investigative ophthalmology & visual science 20070101

Title: Combined 0.1% retinaldehyde/ 6% glycolic acid cream in prophylaxis and treatment of acne scarring.

Journal: Dermatology (Basel, Switzerland) 20070101

Title: Coupling of protonation switches during rhodopsin activation.

Journal: Photochemistry and photobiology 20070101

Title: Clay mimics color tuning in visual pigments.

Journal: Angewandte Chemie (International ed. in English) 20070101

Title: Substitution of Pro206 and Ser86 residues in the retinal binding pocket of Anabaena sensory rhodopsin is not sufficient for proton pumping function.

Journal: Journal of microbiology and biotechnology 20070101

Title: Conformational coupling between the cytoplasmic carboxylic acid and the retinal in a fungal light-driven proton pump.

Journal: Biochemistry 20061226

Title: Predisposition of the dark state of rhodopsin to functional changes in structure.

Journal: Proteins 20061201

Title: A methyl group at C7 of 11-cis-retinal allows chromophore formation but affects rhodopsin activation.

Journal: Vision research 20061201

Title: Arrestin can act as a regulator of rhodopsin photochemistry.

Journal: Vision research 20061201

Title: Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety.

Journal: Clinical interventions in aging 20061201

Title: The photochemical reaction cycle of retinal reconstituted bacteriorhodopsin.

Journal: Journal of photochemistry and photobiology. B, Biology 20061101

Title: The role of the 11-cis-retinal ring methyl substituents in visual pigment formation.

Journal: Chembiochem : a European journal of chemical biology 20061101

Title: Macular degeneration: recent advances and therapeutic opportunities.

Journal: Nature reviews. Neuroscience 20061101

Title: Quantum chemical study of electronic and structural properties of retinal and some aromatic analogs.

Journal: The Journal of chemical physics 20061014

Title: Excited-state properties and environmental effects for protonated schiff bases: a theoretical study.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20061013

Title: Methyl substituents at the 11 or 12 position of retinal profoundly and differentially affect photochemistry and signalling activity of rhodopsin.

Journal: Journal of molecular biology 20061013

Title: Assignment of the hydrogen-out-of-plane and -in-plane vibrations of the retinal chromophore in the K intermediate of pharaonis phoborhodopsin.

Journal: Biochemistry 20061003

Title: Propagating structural perturbation inside bacteriorhodopsin: crystal structures of the M state and the D96A and T46V mutants.

Journal: Biochemistry 20061003

Title: Effect of light exposure on the accumulation and depletion of retinyl ester in the chicken retina.

Journal: Experimental eye research 20061001

Title: Do we live in a quantum world? Advances in multidimensional coherent spectroscopies refine our understanding of quantum coherences and structural dynamics of biological systems.

Journal: Current opinion in structural biology 20061001

Title: Improvement in rod and cone function in mouse model of Fundus albipunctatus after pharmacologic treatment with 9-cis-retinal.

Journal: Investigative ophthalmology & visual science 20061001

Title: Retinal is formed from apo-carotenoids in Nostoc sp. PCC7120: in vitro characterization of an apo-carotenoid oxygenase.

Journal: The Biochemical journal 20060915

Title: Solvent effects on the low-lying excited states of a model of retinal.

Journal: The journal of physical chemistry. B 20060914

Title: Induced chirality of the light-harvesting carotenoid salinixanthin and its interaction with the retinal of xanthorhodopsin.

Journal: Biochemistry 20060912

Title: Chemistry. Controlling biological functions.

Journal: Science (New York, N.Y.) 20060901

Title: Coherent control of retinal isomerization in bacteriorhodopsin.

Journal: Science (New York, N.Y.) 20060901

Title: Exploring the molecular mechanism for color distinction in humans.

Journal: The journal of physical chemistry. B 20060831

Title: Solid-state 2H NMR structure of retinal in metarhodopsin I.

Journal: Journal of the American Chemical Society 20060830

Title: Autosomal recessive retinitis pigmentosa and E150K mutation in the opsin gene.

Journal: The Journal of biological chemistry 20060804

Title: Impacts of two point mutations of RPE65 from Leber's congenital amaurosis on the stability, subcellular localization and isomerohydrolase activity of RPE65.

Journal: FEBS letters 20060724

Title: A novel cytochrome P450, zebrafish Cyp26D1, is involved in metabolism of all-trans retinoic acid.

Journal: Molecular endocrinology (Baltimore, Md.) 20060701

Title: First steps of retinal photoisomerization in proteorhodopsin.

Journal: Biophysical journal 20060701

Title: Ground and excited states of retinal schiff base chromophores by multiconfigurational perturbation theory.

Journal: Biophysical journal 20060701

Title: Effects of quinones and flavonoids on the reduction of all-trans retinal to all-trans retinol in pig heart.

Journal: European journal of pharmacology 20060701

Title: Bacteriorhodopsin chimeras containing the third cytoplasmic loop of bovine rhodopsin activate transducin for GTP/GDP exchange.

Journal: Protein science : a publication of the Protein Society 20060701

Title: Heterogeneity in regeneration of bacteriorhodopsin from bacterio-opsin and all-trans retinal at high temperatures: implications for dynamic structural fluctuations.

Journal: Bioscience, biotechnology, and biochemistry 20060601

Title: Recombination reaction of rhodopsin in situ studied by photoconversion of 'indicator yellow'.

Journal: Vision research 20060501

Title: Novel retinylidene iminium salts for defining opsin shifts: synthesis and intrinsic chromophoric properties.

Journal: Organic & biomolecular chemistry 20060421

Title: Conformational change of bacteriorhodopsin quantitatively monitored by microcantilever sensors.

Journal: Biophysical journal 20060415

Title: FTIR study of the photoisomerization processes in the 13-cis and all-trans forms of Anabaena sensory rhodopsin at 77 K.

Journal: Biochemistry 20060411

Title: Dynamics of arrestin-rhodopsin interactions: acidic phospholipids enable binding of arrestin to purified rhodopsin in detergent.

Journal: The Journal of biological chemistry 20060407

Title: The role of Drosophila ninaG oxidoreductase in visual pigment chromophore biogenesis.

Journal: The Journal of biological chemistry 20060407

Title: Location of Trp265 in metarhodopsin II: implications for the activation mechanism of the visual receptor rhodopsin.

Journal: Journal of molecular biology 20060317

Title: Molecular evolution of adrenoceptors and dopamine receptors: implications for the binding of catecholamines.

Journal: Journal of medicinal chemistry 20060309

Title: Neuroglobin and cytoglobin: oxygen-binding proteins in retinal neurons.

Journal: Investigative ophthalmology & visual science 20060301

Title: RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice.

Journal: Investigative ophthalmology & visual science 20060301

Title: Uncompetitive inhibition of Xenopus laevis aldehyde dehydrogenase 1A1 by divalent cations.

Journal: Zoological science 20060301

Title: Agonists and partial agonists of rhodopsin: retinal polyene methylation affects receptor activation.

Journal: Biochemistry 20060214

Title: Illuminated rhodopsin is required for strong activation of retinal guanylate cyclase by guanylate cyclase-activating proteins.

Journal: Biochemistry 20060214

Title: Circular dichroism of heterochromophoric and partially regenerated purple membrane: search for exciton coupling.

Journal: Chirality 20060201

Title: Computation of vertical excitation energies of retinal and analogs: scope and limitations.

Journal: Journal of computational chemistry 20060115

Title: S1 and S2 excited States of gas-phase Schiff-base retinal chromophores.

Journal: Physical review letters 20060113

Title: Constitutive activity of a UV cone opsin.

Journal: FEBS letters 20060109

Title: Synthesis of enantiopure C3- and C4-hydroxyretinals and their enzymatic reduction by ADH8 from Xenopus laevis.

Journal: Organic & biomolecular chemistry 20060107

Title: Acetaldehyde inhibits the formation of retinoic acid from retinal in the rat esophagus.

Journal: Scandinavian journal of gastroenterology 20060101

Title: Letter: radical ion and protonated molecule formation with retinal in electrospray and nanospray.

Journal: European journal of mass spectrometry (Chichester, England) 20060101

Title: Scaffold proteins and the regeneration of visual pigments.

Journal: Photochemistry and photobiology 20060101

Title: 9-cis Retinal increased in retina of RPE65 knockout mice with decrease in coat pigmentation.

Journal: Photochemistry and photobiology 20060101

Title: UVA and UVB decrease the expression of CD44 and hyaluronate in mouse epidermis, which is counteracted by topical retinoids.

Journal: Photochemistry and photobiology 20060101

Title: [Photochemical properties of a bacteriorhodopsin analogue containing 13-desmethyl-13-(trifluoromethyl)retinal].

Journal: Biofizika 20060101

Title: Computational photochemistry of retinal proteins.

Journal: Journal of computer-aided molecular design 20060101

Title: Design of an ultrasonic micro-array for near field sensing during retinal microsurgery.

Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20060101

Title: Retinal degeneration associated with RDH12 mutations results from decreased 11-cis retinal synthesis due to disruption of the visual cycle.

Journal: Human molecular genetics 20051215

Title: Electrostatic potential at the retinal of three archaeal rhodopsins: implications for their different absorption spectra.

Journal: Proteins 20051201

Title: Steric constraint in the primary photoproduct of an archaeal rhodopsin from regiospecific perturbation of C-D stretching vibration of the retinyl chromophore.

Journal: Journal of the American Chemical Society 20051123

Title: Chemistry. Following the flow of energy in biomolecules.

Journal: Science (New York, N.Y.) 20051111

Title: Structural observation of the primary isomerization in vision with femtosecond-stimulated Raman.

Journal: Science (New York, N.Y.) 20051111

Title: Structural insights into the cellular retinaldehyde-binding protein (CRALBP).

Journal: Proteins 20051101

Title: Synthesis of N-heteroaryl retinals and their artificial bacteriorhodopsins.

Journal: Chembiochem : a European journal of chemical biology 20051101

Title: Partial agonism in a G Protein-coupled receptor: role of the retinal ring structure in rhodopsin activation.

Journal: The Journal of biological chemistry 20051007

Title: Opsin activation of transduction in the rods of dark-reared Rpe65 knockout mice.

Journal: The Journal of physiology 20051001

Title: Cone opsin mislocalization in Rpe65-/- mice: a defect that can be corrected by 11-cis retinal.

Journal: Investigative ophthalmology & visual science 20051001

Title: Efficiency of a few retinoids and carotenoids in vivo in controlling benzo[a]pyrene-induced forestomach tumour in female Swiss mice.

Journal: The British journal of nutrition 20051001

Title: Molecular dynamics simulations of retinal in rhodopsin: from the dark-adapted state towards lumirhodopsin.

Journal: Biochemistry 20050927

Title: Xanthorhodopsin: a proton pump with a light-harvesting carotenoid antenna.

Journal: Science (New York, N.Y.) 20050923

Title: Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20050920

Title: Crystal structure of the 13-cis isomer of bacteriorhodopsin in the dark-adapted state.

Journal: Journal of molecular biology 20050916

Title: Absorption of schiff-base retinal chromophores in vacuo.

Journal: Journal of the American Chemical Society 20050907

Title: Agonists and partial agonists of rhodopsin: retinals with ring modifications.

Journal: Biochemistry 20050906

Title: Expression of keratinocyte transglutaminase in cornea of vitamin A-deficient rats.

Journal: Current eye research 20050901

Title: The retinal G protein-coupled receptor (RGR) enhances isomerohydrolase activity independent of light.

Journal: The Journal of biological chemistry 20050819

Title: Involvement of carbonyl reductase in superoxide formation through redox cycling of adrenochrome and 9,10-phenanthrenequinone in pig heart.

Journal: Chemico-biological interactions 20050815

Title: A tiny excited-state barrier can induce a multiexponential decay of the retinal chromophore: a quantum dynamics investigation.

Journal: Angewandte Chemie (International ed. in English) 20050812

Title: Tuning of retinal twisting in bacteriorhodopsin controls the directionality of the early photocycle steps.

Journal: The journal of physical chemistry. B 20050811

Title: Probing the ultrafast charge translocation of photoexcited retinal in bacteriorhodopsin.

Journal: Science (New York, N.Y.) 20050805

Title: Mole quantity of RPE65 and its productivity in the generation of 11-cis-retinal from retinyl esters in the living mouse eye.

Journal: Biochemistry 20050726

Title: Intrinsically photosensitive retinal ganglion cells detect light with a vitamin A-based photopigment, melanopsin.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20050719

Title: Breaking the covalent bond--a pigment property that contributes to desensitization in cones.

Journal: Neuron 20050616

Title: Titration of the bacteriorhodopsin Schiff base involves titration of an additional protein residue.

Journal: Biochemistry 20050614

Title: FTIR studies of the photoactivation processes in squid retinochrome.

Journal: Biochemistry 20050607

Title: Novel mutation in RLBP1 gene in a Japanese patient with retinitis punctata albescens.

Journal: American journal of ophthalmology 20050601

Title: [Gene clone and sequence analysis of retinal specific rho promoter].

Journal: Yan ke xue bao = Eye science 20050601

Title: Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.

Journal: The Journal of biological chemistry 20050513

Title: Biochemical properties of purified human retinol dehydrogenase 12 (RDH12): catalytic efficiency toward retinoids and C9 aldehydes and effects of cellular retinol-binding protein type I (CRBPI) and cellular retinaldehyde-binding protein (CRALBP) on the oxidation and reduction of retinoids.

Journal: Biochemistry 20050510

Title: Exploring the potential energy surface of retinal, a comparison of the performance of different methods.

Journal: Journal of computational chemistry 20050501

Title: Vitamin a deficiency in patients with common variable immunodeficiency.

Journal: Journal of clinical immunology 20050501

Title: Selective interface detection: mapping binding site contacts in membrane proteins by NMR spectroscopy.

Journal: Journal of the American Chemical Society 20050427

Title: Photochromicity of Anabaena sensory rhodopsin, an atypical microbial receptor with a cis-retinal light-adapted form.

Journal: The Journal of biological chemistry 20050415

Title: The structure of a retinal-forming carotenoid oxygenase.

Journal: Science (New York, N.Y.) 20050408

Title: Downregulation of cone-specific gene expression and degeneration of cone photoreceptors in the Rpe65-/- mouse at early ages.

Journal: Investigative ophthalmology & visual science 20050401

Title: Ultrafast excited state dynamics of the protonated Schiff base of all-trans retinal in solvents.

Journal: Biophysical journal 20050401

Title: The Drosophila ninaG oxidoreductase acts in visual pigment chromophore production.

Journal: The Journal of biological chemistry 20050325

Title: Calculating absorption shifts for retinal proteins: computational challenges.

Journal: The journal of physical chemistry. B 20050303

Title: Photoisomerization mechanism of 11-cis-locked artificial retinal chromophores: acceleration and primary photoproduct assignment.

Journal: Journal of the American Chemical Society 20050302

Title: Reduction of all-trans retinal to all-trans retinol in the outer segments of frog and mouse rod photoreceptors.

Journal: Biophysical journal 20050301

Title: Restored epidermal CD44 expression in lichen sclerosus et atrophicus and clinical improvement with topical application of retinaldehyde.

Journal: The British journal of dermatology 20050301

Title: Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA).

Journal: Molecular vision 20050227

Title: Dynamics of arrestin-rhodopsin interactions: arrestin and retinal release are directly linked events.

Journal: The Journal of biological chemistry 20050225

Title: Addition of human melanopsin renders mammalian cells photoresponsive.

Journal: Nature 20050217

Title: Neurobiology: bright blue times.

Journal: Nature 20050217

Title: Water dynamics simulation as a tool for probing proton transfer pathways in a heptahelical membrane protein.

Journal: Proteins 20050215

Title: pH-dependent photoisomerization of retinal in proteorhodopsin.

Journal: Biochemistry 20050215

Title: Amino acid residues responsible for the meta-III decay rates in rod and cone visual pigments.

Journal: Biochemistry 20050215

Title: Cis-retinol dehydrogenase: 9-cis-retinol metabolism and its effect on proliferation of human MCF7 breast cancer cells.

Journal: Experimental cell research 20050201

Title: [Function of bestrophin].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20050201

Title: Retinal biosynthesis in Eubacteria: in vitro characterization of a novel carotenoid oxygenase from Synechocystis sp. PCC 6803.

Journal: Molecular microbiology 20050201

Title: Illumination of the melanopsin signaling pathway.

Journal: Science (New York, N.Y.) 20050128

Title: A dark and constitutively active mutant of the tiger salamander UV pigment.

Journal: Biochemistry 20050118

Title: High-field EPR spectroscopy applied to biological systems: characterization of molecular switches for electron and ion transfer.

Journal: Physical chemistry chemical physics : PCCP 20050107

Title: Accurate CSA measurements from uniformly isotopically labeled biomolecules at high magnetic field.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20050101

Title: Regeneration of bacteriorhodopsin from thermally unfolded bacterio-opsin and all-trans retinal at high temperatures.

Journal: Bioscience, biotechnology, and biochemistry 20050101

Title: Retinoid metabolism in the rat small intestine.

Journal: The British journal of nutrition 20050101

Title: Mixing glycolic acid with retinaldehyde: RALGA, a technical achievement.

Journal: Dermatology (Basel, Switzerland) 20050101

Title: Pharmacology of RALGA, a mixture of retinaldehyde and glycolic acid.

Journal: Dermatology (Basel, Switzerland) 20050101

Title: Efficacy and safety of 0.1% retinaldehyde/ 6% glycolic acid (diacneal) for mild to moderate acne vulgaris. A multicentre, double-blind, randomized, vehicle-controlled trial.

Journal: Dermatology (Basel, Switzerland) 20050101

Title: Topical retinaldehyde with glycolic acid: study of tolerance and acceptability in association with anti-acne treatments in 1,709 patients.

Journal: Dermatology (Basel, Switzerland) 20050101

Title: The depigmenting effect of RALGA in C57BL/6 mice.

Journal: Dermatology (Basel, Switzerland) 20050101

Title: RALGA (Diacneal) decreases melanin content in a human skin model.

Journal: Dermatology (Basel, Switzerland) 20050101

Title: RALGA (Diacneal), a retinaldehyde and glycolic acid association and postinflammatory hyperpigmentation in acne--a review.

Journal: Dermatology (Basel, Switzerland) 20050101

Title: Partial dehydration of the retinal binding pocket and proof for photochemical deprotonation of the retinal Schiff base in bicelle bacteriorhodopsin crystals.

Journal: Photochemistry and photobiology 20050101

Title: Light-induced damage to the retina: role of rhodopsin chromophore revisited.

Journal: Photochemistry and photobiology 20050101

Title: Comparative study of the anti-aging effect of retinaldehyde alone or associated with pretocopheryl in a surviving human skin model submitted to ultraviolet A and B irradiation.

Journal: International journal of tissue reactions 20050101

Title: N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR).

Journal: The Journal of biological chemistry 20041224

Title: Counterion controlled photoisomerization of retinal chromophore models: a computational investigation.

Journal: Journal of the American Chemical Society 20041215

Title: Activation and function of mitochondrial uncoupling protein in plants.

Journal: The Journal of biological chemistry 20041210

Title: Effect of vitamin A depletion on nonvisual phototransduction pathways in cryptochromeless mice.

Journal: Journal of biological rhythms 20041201

Title: A molecular spring for vision.

Journal: Journal of the American Chemical Society 20041201

Title: Retinal is the essential form of retinoid for storage and transport in the adult of the ascidian Halocynthia roretzi.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20041201

Title: Constraints of the 9-methyl group binding pocket of the rhodopsin chromophore probed by 9-halogeno substitution.

Journal: Biochemistry 20041123

Title: Synthesis of ring-oxidized retinoids as substrates of mouse class I alcohol dehydrogenase (ADH1).

Journal: Organic & biomolecular chemistry 20041121

Title: Transition of rhodopsin into the active metarhodopsin II state opens a new light-induced pathway linked to Schiff base isomerization.

Journal: The Journal of biological chemistry 20041112

Title: Key role of electrostatic interactions in bacteriorhodopsin proton transfer.

Journal: Journal of the American Chemical Society 20041110

Title: Patterns of retinal light absorption related to retinitis pigmentosa mutants from in silico model structures of rhodopsin.

Journal: Proteins 20041101

Title: Absolute configurational determination of an all-trans-retinal dimer isolated from photoreceptor outer segments.

Journal: Chirality 20041101

Title: TD-DFT calculations of the potential energy curves for the trans-cis photo-isomerization of protonated Schiff base of retinal.

Journal: Journal of photochemistry and photobiology. B, Biology 20041025

Title: Deuterium NMR structure of retinal in the ground state of rhodopsin.

Journal: Biochemistry 20041012

Title: Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro.

Journal: Experimental neurology 20041001

Title: The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure.

Journal: Journal of molecular biology 20040910

Title: Different SAR86 subgroups harbour divergent proteorhodopsins.

Journal: Environmental microbiology 20040901

Title: Support for a proposed retinoid-processing protein complex in apical retinal pigment epithelium.

Journal: Experimental eye research 20040901

Title: The quantum topological electrostatic potential as a probe for functional group transferability.

Journal: Acta crystallographica. Section A, Foundations of crystallography 20040901

Title: FTIR spectroscopy of the K photointermediate of Neurospora rhodopsin: structural changes of the retinal, protein, and water molecules after photoisomerization.

Journal: Biochemistry 20040803

Title: Impact of noise on retinal coding of visual signals.

Journal: Journal of neurophysiology 20040801

Title: [Visual cycle and dark adaptation: a new approach in research].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20040801

Title: What is the real crystallographic structure of the L photointermediate of bacteriorhodopsin?

Journal: Biochimica et biophysica acta 20040723

Title: Toward the active conformations of rhodopsin and the beta2-adrenergic receptor.

Journal: Proteins 20040701

Title: A novel compound heterozygous mutation in the cellular retinaldehyde-binding protein gene (RLBP1) in a patient with retinitis punctata albescens.

Journal: American journal of ophthalmology 20040701

Title: The visual cycle of the cone photoreceptors of the retina.

Journal: Nutrition reviews 20040701

Title: Identification of CRALBP ligand interactions by photoaffinity labeling, hydrogen/deuterium exchange, and structural modeling.

Journal: The Journal of biological chemistry 20040625

Title: Femtosecond primary events in bacteriorhodopsin and its retinal modified analogs: revision of commonly accepted interpretation of electronic spectra of transient intermediates in the bacteriorhodopsin photocycle.

Journal: The Journal of chemical physics 20040615

Title: A palmitoylation switch mechanism in the regulation of the visual cycle.

Journal: Cell 20040611

Title: FTIR spectroscopy of the O photointermediate in pharaonis phoborhodopsin.

Journal: Biochemistry 20040511

Title: Role of the 9-methyl group of retinal in cone visual pigments.

Journal: Biochemistry 20040511

Title: In vivo treatment with CPT-11 leads to differentiation of neuroblastoma xenografts and topoisomerase I alterations.

Journal: Cancer research 20040501

Title: Ultrasound imaging demonstration of the improvement of non-ablative laser remodeling by concomitant daily topical application of 0.05% retinaldehyde.

Journal: Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology 20040501

Title: Drosophila ninaB and ninaD act outside of retina to produce rhodopsin chromophore.

Journal: The Journal of biological chemistry 20040430

Title: Effect of beta-particles on the retinal chromophore in bacteriorhodopsin of Halobacterium salinarium.

Journal: Radiation measurements 20040401

Title: Impairment of the transient pupillary light reflex in Rpe65(-/-) mice and humans with leber congenital amaurosis.

Journal: Investigative ophthalmology & visual science 20040401

Title: [The frosted retinal vascular branch syndrome].

Journal: Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti 20040401

Title: Light adaptation of bacteriorhodopsin correlates with dielectric spectral kinetics in purple membrane.

Journal: Biochemical and biophysical research communications 20040319

Title: The nitrate transporting photochemical reaction cycle of the pharaonis halorhodopsin.

Journal: Biophysical journal 20040301

Title: A purified agonist-activated G-protein coupled receptor: truncated octopus Acid Metarhodopsin.

Journal: Zoological science 20040301

Title: Induction of 1,N(2)-etheno-2'-deoxyguanosine in DNA exposed to beta-carotene oxidation products.

Journal: FEBS letters 20040227

Title: Selectivity of retinal photoisomerization in proteorhodopsin is controlled by aspartic acid 227.

Journal: Biochemistry 20040217

Title: Cellular retinaldehyde-binding protein interacts with ERM-binding phosphoprotein 50 in retinal pigment epithelium.

Journal: Investigative ophthalmology & visual science 20040201

Title: Crystal structure of the L intermediate of bacteriorhodopsin: evidence for vertical translocation of a water molecule during the proton pumping cycle.

Journal: Journal of molecular biology 20040109

Title: Novel mutations in the cellular retinaldehyde-binding protein gene (RLBP1) associated with retinitis punctata albescens: evidence of interfamilial genetic heterogeneity and fundus changes in heterozygotes.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20040101

Title: Isotretinoin treatment inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration.

Journal: Novartis Foundation symposium 20040101

Title: Primary events in dim light vision: a chemical and spectroscopic approach toward understanding protein/chromophore interactions in rhodopsin.

Journal: Chemical record (New York, N.Y.) 20040101

Title: Interaction of class A G protein-coupled receptors with G proteins.

Journal: Acta biochimica Polonica 20040101

Title: X-ray diffraction of bacteriorhodopsin photocycle intermediates.

Journal: Molecular membrane biology 20040101

Title: Second harmonic imaging of membrane potential of neurons with retinal.

Journal: Journal of biomedical optics 20040101

Title: Retinaldehyde, a potent inhibitor of gap junctional intercellular communication.

Journal: Cell communication & adhesion 20040101

Title: Positive, accurate animal identification.

Journal: Animal reproduction science 20031215

Title: (9Z)- and (11Z)-8-methylretinals for artificial visual pigment studies: stereoselective synthesis, structure, and binding models.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20031205

Title: Human requirements for fat-soluble vitamins, and other things concerning these nutrients.

Journal: Molecular aspects of medicine 20031201

Title: Retinoid cycle in the vertebrate retina: experimental approaches and mechanisms of isomerization.

Journal: Vision research 20031201

Title: A2E, a byproduct of the visual cycle.

Journal: Vision research 20031201

Title: Secondary binding sites of retinoids in opsin: characterization and role in regeneration.

Journal: Vision research 20031201

Title: Bleaching desensitization: background and current challenges.

Journal: Vision research 20031201

Title: Interphotoreceptor retinoid-binding protein--an old gene for new eyes.

Journal: Vision research 20031201

Title: Availability of 11-cis retinal and opsins without chromophore as revealed by small bleaches of rhodopsin in excised albino mouse eyes.

Journal: Vision research 20031201

Title: Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term surgical trials.

Journal: Investigative ophthalmology & visual science 20031201

Title: Specific isomerization of rhodopsin-bound 11-cis-retinal to all-trans-retinal under thermal denaturation.

Journal: Cellular and molecular life sciences : CMLS 20031101

Title: Excited-state singlet manifold and oscillatory features of a nonatetraeniminium retinal chromophore model.

Journal: Journal of the American Chemical Society 20031015

Title: Heterogeneity effects in the binding of all-trans retinal to bacterio-opsin.

Journal: Biochemistry 20030930

Title: Molecular dynamics simulation of bacteriorhodopsin's photoisomerization using ab initio forces for the excited chromophore.

Journal: Biophysical journal 20030901

Title: A photochemical study of (E,E,E,E)-2-[9-(2-hydroxyethyl)imino-3,7-dimethyl-1,3,5,7-decatrien-1-yl]- 1,3,3-trimethylcyclohexene, a derivative of all-trans-retinal and ethanolamine.

Journal: Photochemistry and photobiology 20030901

Title: Structural changes of water molecules during the photoactivation processes in bovine rhodopsin.

Journal: Biochemistry 20030819

Title: Crystallographic structures of the M and N intermediates of bacteriorhodopsin: assembly of a hydrogen-bonded chain of water molecules between Asp-96 and the retinal Schiff base.

Journal: Journal of molecular biology 20030711

Title: Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin.

Journal: The Journal of biological chemistry 20030704

Title: Opsin activation as a cause of congenital night blindness.

Journal: Nature neuroscience 20030701

Title: Probing the rhodopsin cavity with reduced retinal models at the CASPT2//CASSCF/AMBER level of theory.

Journal: Journal of the American Chemical Society 20030611

Title: Photoexcitation of the O-intermediate in bacteriorhodopsin mutant L93A.

Journal: Biophysical journal 20030601

Title: Molecular basis of spectral tuning in the newt short wavelength sensitive visual pigment.

Journal: Biochemistry 20030527

Title: Enzymatic characterization of recombinant mouse retinal dehydrogenase type 1.

Journal: Biochemical pharmacology 20030515

Title: Provitamin A conversion to retinal via the beta,beta-carotene-15,15'-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis.

Journal: Development (Cambridge, England) 20030501

Title: Evaluation of the role of the retinal G protein-coupled receptor (RGR) in the vertebrate retina in vivo.

Journal: Journal of neurochemistry 20030501

Title: Mechanism of proton transport in bacteriorhodopsin from crystallographic structures of the K, L, M1, M2, and M2' intermediates of the photocycle.

Journal: Journal of molecular biology 20030425

Title: Reduction of all-trans-retinal in the mouse liver peroxisome fraction by the short-chain dehydrogenase/reductase RRD: induction by the PPAR alpha ligand clofibrate.

Journal: Biochemistry 20030415

Title: The photoreceptive capacity of the developing pineal gland and eye of the golden hamster (Mesocricetus auratus).

Journal: Journal of neuroendocrinology 20030401

Title: Acute radiolabeling of retinoids in eye tissues of normal and rpe65-deficient mice.

Journal: Investigative ophthalmology & visual science 20030401

Title: Decisive role of electronic polarization of the protein environment in determining the absorption maximum of halorhodopsin.

Journal: Journal of the American Chemical Society 20030312

Title: Relationship between photoisomerization path and intersection space in a retinal chromophore model.

Journal: Journal of the American Chemical Society 20030305

Title: Demonstration of a sensory rhodopsin in eubacteria.

Journal: Molecular microbiology 20030301

Title: Comparison of the aerobic photoreactivity of A2E with its precursor retinal.

Journal: Photochemistry and photobiology 20030301

Title: An opsin mutant with increased thermal stability.

Journal: Biochemistry 20030225

Title: Slow binding of retinal to rhodopsin mutants G90D and T94D.

Journal: Biochemistry 20030225

Title: Storage of retinal in the eggs of the ascidian, Halocynthia roretzi.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030201

Title: Cloning of monkey RALDH1 and characterization of retinoid metabolism in monkey kidney proximal tubule cells.

Journal: Journal of lipid research 20030201

Title: Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid.

Journal: Chemico-biological interactions 20030201

Title: Signaling states of rhodopsin. Formation of the storage form, metarhodopsin III, from active metarhodopsin II.

Journal: The Journal of biological chemistry 20030131

Title: Correlation of regenerable opsin with rod ERG signal in Rpe65-/- mice during development and aging.

Journal: Investigative ophthalmology & visual science 20030101

Title: Fourier transform IR spectroscopy study for new insights into molecular properties and activation mechanisms of visual pigment rhodopsin.

Journal: Biopolymers 20030101

Title: Visually perceived eye level with reversible pitch stimuli: implications for the great circle and implicit surface models.

Journal: Perception 20030101

Title: Differential expression of heparin-binding EGF-like growth factor (HB-EGF) mRNA in normal human keratinocytes induced by a variety of natural and synthetic retinoids.

Journal: Experimental dermatology 20030101

Title: A2E, a fluorophore of RPE lipofuscin: can it cause RPE degeneration?

Journal: Advances in experimental medicine and biology 20030101

Title: 11-cis-retinal protonated Schiff base: influence of the protein environment on the geometry of the rhodopsin chromophore.

Journal: Biochemistry 20021224

Title: Molecular dynamics investigation of primary photoinduced events in the activation of rhodopsin.

Journal: Biophysical journal 20021201

Title: Bacteriorhodopsin analog regenerated with 13-desmethyl-13-iodoretinal.

Journal: Biophysical journal 20021201

Title: Constraints of opsin structure on the ligand-binding site: studies with ring-fused retinals.

Journal: Photochemistry and photobiology 20021201

Title: Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina.

Journal: The Journal of biological chemistry 20021122

Title: Amphioxus homologs of Go-coupled rhodopsin and peropsin having 11-cis- and all-trans-retinals as their chromophores.

Journal: FEBS letters 20021120

Title: Biochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinals.

Journal: The Journal of biological chemistry 20021101

Title: Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE.

Journal: Investigative ophthalmology & visual science 20021101

Title: 11-cis-retinal reduces constitutive opsin phosphorylation and improves quantum catch in retinoid-deficient mouse rod photoreceptors.

Journal: The Journal of biological chemistry 20021025

Title: Rhodopsin with 11-cis-locked chromophore is capable of forming an active state photoproduct.

Journal: The Journal of biological chemistry 20021025

Title: Bacteriorhodopsin: a high-resolution structural view of vectorial proton transport.

Journal: Biochimica et biophysica acta 20021011

Title: Structural studies on rhodopsin.

Journal: Biochimica et biophysica acta 20021011

Title: Structural basis for sensory rhodopsin function.

Journal: Biochimica et biophysica acta 20021011

Title: Light-induced charge redistribution in the retinal chromophore is required for initiating the bacteriorhodopsin photocycle.

Journal: Journal of the American Chemical Society 20021009

Title: Crystal structure of rhodopsin: a G-protein-coupled receptor.

Journal: Chembiochem : a European journal of chemical biology 20021004

Title: Active states of rhodopsin.

Journal: Chembiochem : a European journal of chemical biology 20021004

Title: Relaxation of beta-structure in tear lipocalin and enhancement of retinoid binding.

Journal: Investigative ophthalmology & visual science 20021001

Title: Like night and day: rods and cones have different pigment regeneration pathways.

Journal: Neuron 20020926

Title: Isomerization and oxidation of vitamin a in cone-dominant retinas: a novel pathway for visual-pigment regeneration in daylight.

Journal: Neuron 20020926

Title: Large-scale morphological survey of mouse retinal ganglion cells.

Journal: The Journal of comparative neurology 20020916

Title: Early steps of the intramolecular signal transduction in rhodopsin explored by molecular dynamics simulations.

Journal: Biochemistry 20020903

Title: Recreating a functional ancestral archosaur visual pigment.

Journal: Molecular biology and evolution 20020901

Title: Selected retinoids: determination by isocratic normal-phase HPLC.

Journal: Endocrine regulations 20020901

Title: Crystallographic structure of the K intermediate of bacteriorhodopsin: conservation of free energy after photoisomerization of the retinal.

Journal: Journal of molecular biology 20020823

Title: Crystallographic structure of the retinal and the protein after deprotonation of the Schiff base: the switch in the bacteriorhodopsin photocycle.

Journal: Journal of molecular biology 20020823

Title: Opsins and melanopsins.

Journal: Current biology : CB 20020820

Title: Vibrational polarization and opsin shift of retinal schiff bases: theoretical study.

Journal: Journal of the American Chemical Society 20020807

Title: Femtosecond infrared spectroscopy of bacteriorhodopsin chromophore isomerization.

Journal: Science (New York, N.Y.) 20020802

Title: Beta-carotene cleavage products induce oxidative stress in vitro by impairing mitochondrial respiration.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020801

Title: The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation.

Journal: Journal of cell science 20020715

Title: Channelrhodopsin-1: a light-gated proton channel in green algae.

Journal: Science (New York, N.Y.) 20020628

Title: Solution and biologically relevant conformations of enantiomeric 11-cis-locked cyclopropyl retinals.

Journal: Journal of the American Chemical Society 20020626

Title: All-trans-retinal shuts down rod cyclic nucleotide-gated ion channels: a novel role for photoreceptor retinoids in the response to bright light?

Journal: Proceedings of the National Academy of Sciences of the United States of America 20020611

Title: The preparation of all-trans uniformly (13)C-labeled retinal via a modular total organic synthetic strategy. emerging central contribution of organic synthesis toward the structure and function study with atomic resolution in protein research.

Journal: Journal of the American Chemical Society 20020605

Title: Photoreduction of bacteriorhodopsin Schiff base at low humidity. A study with C13=C14 nonisomerizable artificial pigments.

Journal: Photochemistry and photobiology 20020601

Title: Proton translocation by bacteriorhodopsin in the absence of substantial conformational changes.

Journal: Journal of molecular biology 20020531

Title: Recovery of visual functions in a mouse model of Leber congenital amaurosis.

Journal: The Journal of biological chemistry 20020524

Title: A pharaonis phoborhodopsin mutant with the same retinal binding site residues as in bacteriorhodopsin.

Journal: Biochemistry 20020521

Title: Recombinant class I aldehyde dehydrogenases specific for all-trans- or 9-cis-retinal.

Journal: The Journal of biological chemistry 20020517

Title: Synthesis of 11-cis-locked bicyclo[5.1.0]octanyl retinal and an enantioselective binding to bovine opsin.

Journal: Chirality 20020505

Title: Light-induced hydrolysis and rebinding of nonisomerizable bacteriorhodopsin pigment.

Journal: Biophysical journal 20020501

Title: Reaction path analysis of the 'tunable' photoisomerization selectivity of free and locked retinal chromophores.

Journal: Journal of the American Chemical Society 20020417

Title: Interaction of Asn105 with the retinal chromophore during photoisomerization of pharaonis phoborhodopsin.

Journal: Biochemistry 20020409

Title: Electronic excitations of biomolecules studied by quantum chemistry.

Journal: Current opinion in structural biology 20020401

Title: All-trans to 13-cis retinal isomerization in light-adapted bacteriorhodopsin at acidic pH.

Journal: Journal of photochemistry and photobiology. B, Biology 20020401

Title: Effects of light and low oxygen tension on pigment biosynthesis in Halobacterium salinarum, revealed by a novel method to quantify both retinal and carotenoids.

Journal: Plant & cell physiology 20020401

Title: Kinetic analysis of mouse retinal dehydrogenase type-2 (RALDH2) for retinal substrates.

Journal: Biochimica et biophysica acta 20020401

Title: Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases.

Journal: Biochimica et biophysica acta 20020220

Title: Tryptophan interactions in bacteriorhodopsin: a heteronuclear solid-state NMR study.

Journal: Biochemistry 20020219

Title: Bleaching kinetics of artificial visual pigments with modifications near the ring-polyene chain connection.

Journal: Biochemistry 20020212

Title: Synthesis of the all-trans-retinal chromophore of retinal G protein-coupled receptor opsin in cultured pigment epithelial cells.

Journal: The Journal of biological chemistry 20020201

Title: Retinoid composition and retinal localization in the eggs of teleost fishes.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020201

Title: Changes in the retinal transition dipole moment in bacteriorhodopsin of the purple membrane of Halobacterium Salinarium at the so-called PH(rev).

Journal: Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) 20020201

Title: Combined QM/MM study of the opsin shift in bacteriorhodopsin.

Journal: Journal of computational chemistry 20020115

Title: Selective photostimulation of genetically chARGed neurons.

Journal: Neuron 20020103

Title: Use of retinal analogues for the study of visual pigment function.

Journal: Methods in enzymology 20020101

Title: The eye as metronome of the body.

Journal: Survey of ophthalmology 20020101

Title: 4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of all-trans retinal to all-trans retinoic acid by ALDH1A1, but not the differentiation of HL-60 promyelocytic leukemia cells exposed to all-trans retinal.

Journal: BMC pharmacology 20020101

Title: Designing and characterizing hammerhead ribozymes for use in AAV vector-mediated retinal gene therapies.

Journal: Methods in enzymology 20020101

Title: Energy transfer from tryptophane amino acid residues to retinal in a bacteriorhodopsin molecule within a femtosecond timescale.

Journal: Doklady. Biochemistry and biophysics 20020101

Title: A retrospective study of the effect of long-term topical application of retinaldehyde (0.05%) on the development of actinic keratosis.

Journal: Dermatology (Basel, Switzerland) 20020101

Title: The antibacterial activity of topical retinoids: the case of retinaldehyde.

Journal: Dermatology (Basel, Switzerland) 20020101

Title: [A convenient synthesis of retinal derivatives with a modified trimethylcyclohexene ring].

Journal: Bioorganicheskaia khimiia 20020101

Title: Topical retinaldehyde treatment in oral lichen planus and leukoplakia.

Journal: International journal of tissue reactions 20020101

Title: Biochemical defects in 11-cis-retinol dehydrogenase mutants associated with fundus albipunctatus.

Journal: The Journal of biological chemistry 20011228

Title: Environment around the chromophore in pharaonis phoborhodopsin: mutation analysis of the retinal binding site.

Journal: Biochimica et biophysica acta 20011201

Title: Direction tuning of inhibitory inputs to the turtle accessory optic system.

Journal: Journal of neurophysiology 20011201

Title: A semiempirical study of the optimized ground and excited state potential energy surfaces of retinal and its protonated Schiff base.

Journal: Journal of photochemistry and photobiology. B, Biology 20011201

Title: The nature of the delocalized cations in azulenic bacteriorhodopsin analogs.

Journal: Photochemistry and photobiology 20011201

Title: Real-time spectroscopy of transition states in bacteriorhodopsin during retinal isomerization.

Journal: Nature 20011129

Title: Regulation of phototransduction in short-wavelength cone visual pigments via the retinylidene Schiff base counterion.

Journal: Biochemistry 20011120

Title: Wavelength dependent cis-trans isomerization in vision.

Journal: Biochemistry 20011120

Title: Retinal isomerization in bacteriorhodopsin is controlled by specific chromophore-protein interactions. A study with noncovalent artificial pigments.

Journal: Biochemistry 20011106

Title: Photoreceptor current and photoorientation in chlamydomonas mediated by 9-demethylchlamyrhodopsin.

Journal: Biophysical journal 20011101

Title: Effect of Rpe65 knockout on accumulation of lipofuscin fluorophores in the retinal pigment epithelium.

Journal: Investigative ophthalmology & visual science 20011101

Title: Estimation of carbon-carbon bond lengths and medium-range internuclear distances by solid-state nuclear magnetic resonance.

Journal: Journal of the American Chemical Society 20011031

Title: Crystal structure of the D85S mutant of bacteriorhodopsin: model of an O-like photocycle intermediate.

Journal: Journal of molecular biology 20011026

Title: Steric barrier to bathorhodopsin decay in 5-demethyl and mesityl analogues of rhodopsin.

Journal: Journal of the American Chemical Society 20011017

Title: Metabolism of vitamin A affected by prostaglandin F synthase in contractile interstitial cells of bovine lung.

Journal: Biochemical and biophysical research communications 20011005

Title: Rhodopsin: structural basis of molecular physiology.

Journal: Physiological reviews 20011001

Title: Retinoic acid biosynthesis by normal human breast epithelium is via aldehyde dehydrogenase 6, absent in MCF-7 cells.

Journal: Cancer research 20011001

Title: On the bioactive conformation of the rhodopsin chromophore: absolute sense of twist around the 6-s-cis bond.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20011001

Title: Coupling of the reisomerization of the retinal, proton uptake, and reprotonation of Asp-96 in the N photointermediate of bacteriorhodopsin.

Journal: Biochemistry 20010925

Title: Kinetics of photo-active bacteriorhodopsin analog 3,4-didehydroretinal.

Journal: Journal of photochemistry and photobiology. B, Biology 20010915

Title: Crystal structure of sensory rhodopsin II at 2.4 angstroms: insights into color tuning and transducer interaction.

Journal: Science (New York, N.Y.) 20010824

Title: Structural changes of pharaonis phoborhodopsin upon photoisomerization of the retinal chromophore: infrared spectral comparison with bacteriorhodopsin.

Journal: Biochemistry 20010807

Title: The effects of 3,4,3'-triiodo-l-thyronine on didehydroretinol synthesis by isolated coho salmon retinal pigment epithelial cells.

Journal: General and comparative endocrinology 20010801

Title: Bacteriorhodopsin.

Journal: Current opinion in structural biology 20010801

Title: Crystal structure of rhodopsin: implications for vision and beyond.

Journal: Current opinion in structural biology 20010801

Title: Multiple phosphorylation of rhodopsin and the in vivo chemistry underlying rod photoreceptor dark adaptation.

Journal: Neuron 20010719

Title: A photic visual cycle of rhodopsin regeneration is dependent on Rgr.

Journal: Nature genetics 20010701

Title: Engineering a functional blue-wavelength-shifted rhodopsin mutant.

Journal: Biochemistry 20010619

Title: Interaction of 11-cis-retinol dehydrogenase with the chromophore of retinal g protein-coupled receptor opsin.

Journal: The Journal of biological chemistry 20010615

Title: Simultaneous quantification of retinol, retinal, and retinoic acid isomers by high-performance liquid chromatography with a simple gradiation.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010615

Title: Proteorhodopsin phototrophy in the ocean.

Journal: Nature 20010614

Title: The effect of metal cation binding on the protein, lipid and retinal isomeric ratio in regenerated bacteriorhodopsin of purple membrane.

Journal: Photochemistry and photobiology 20010501

Title: Standard apparent reduction potentials for biochemical half reactions as a function of pH and ionic strength.

Journal: Archives of biochemistry and biophysics 20010501

Title: Differential effects of retinoids on proliferation of bovine mammary epithelial cells in collagen gel culture.

Journal: The Journal of dairy research 20010501

Title: Free radical lipid peroxidation inhibits enzymatic conversion of beta-carotene into vitamin A.

Journal: Bulletin of experimental biology and medicine 20010501

Title: Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A.

Journal: The Journal of biological chemistry 20010427

Title: Time-resolved FT-IR spectroscopic investigation of the pH-dependent proton transfer reactions in the E194Q mutant of bacteriorhodopsin.

Journal: Biochemical and biophysical research communications 20010427

Title: Structure and function in bacteriorhodopsin: the role of the interhelical loops in the folding and stability of bacteriorhodopsin.

Journal: Journal of molecular biology 20010427

Title: Structure and function in bacteriorhodopsin: the effect of the interhelical loops on the protein folding kinetics.

Journal: Journal of molecular biology 20010427

Title: Proline residues in transmembrane alpha helices affect the folding of bacteriorhodopsin.

Journal: Journal of molecular biology 20010427

Title: ABCR, the ATP-binding cassette transporter responsible for Stargardt macular dystrophy, is an efficient target of all-trans-retinal-mediated photooxidative damage in vitro. Implications for retinal disease.

Journal: The Journal of biological chemistry 20010413

Title: All-trans-retinal forms a visible-absorbing pigment with human rod opsin.

Journal: Biochemistry 20010410

Title: Halide dependence of the halorhodopsin photocycle as measured by time-resolved infrared spectra.

Journal: Biophysical journal 20010301

Title: The relationship between opsin overexpression and photoreceptor degeneration.

Journal: Investigative ophthalmology & visual science 20010301

Title: Visual cycle impairment in cellular retinaldehyde binding protein (CRALBP) knockout mice results in delayed dark adaptation.

Journal: Neuron 20010301

Title: Role of noncovalent binding of 11-cis-retinal to opsin in dark adaptation of rod and cone photoreceptors.

Journal: Neuron 20010301

Title: brp and blh are required for synthesis of the retinal cofactor of bacteriorhodopsin in Halobacterium salinarum.

Journal: The Journal of biological chemistry 20010223

Title: Interphotoreceptor retinoid-binding protein contains three retinoid binding sites.

Journal: Experimental eye research 20010201

Title: Ocular phenotype of bothnia dystrophy, an autosomal recessive retinitis pigmentosa associated with an R234W mutation in the RLBP1 gene.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20010201

Title: Ternary complexes of liver alcohol dehydrogenase.

Journal: Chemico-biological interactions 20010130

Title: Bioinorganic and bioorganic studies of liver alcohol dehydrogenase.

Journal: Chemico-biological interactions 20010130

Title: Salt dependence of the formation and stability of the signaling state in G protein-coupled receptors: evidence for the involvement of the Hofmeister effect.

Journal: Biochemistry 20010116

Title: Inherent chirality of the retinal chromophore in rhodopsin-A nonempirical theoretical analysis of chiroptical data.

Journal: Chirality 20010101

Title: Nucleotide and deduced amino acid sequence of equine retinal and pineal gland phosducin.

Journal: American journal of veterinary research 20010101

Title: Studies of all-trans-retinal as a photooxidizing agent.

Journal: Photochemistry and photobiology 20010101

Title: The role of retinal in the long-range protein-lipid interactions in bacteriorhodopsin-phosphatidylcholine vesicles.

Journal: European biophysics journal : EBJ 20010101

Title: Xanthine oxidase catalyzes the synthesis of retinoic acid.

Journal: Journal of enzyme inhibition 20010101

Title: Oxidative DNA damage by vitamin A and its derivative via superoxide generation.

Journal: The Journal of biological chemistry 20000121

Title: Metabolism of retinaldehyde and other aldehydes in soluble extracts of human liver and kidney.

Journal: The Journal of biological chemistry 19991119

Title: Tolerance profile of retinol, retinaldehyde and retinoic acid under maximized and long-term clinical conditions.

Journal: Dermatology (Basel, Switzerland) 19990101

Title: Structural and functional characterization of recombinant human cellular retinaldehyde-binding protein.

Journal: Protein science : a publication of the Protein Society 19980301

Title: Synthesis and characterization of a novel retinylamine analog inhibitor of constitutively active rhodopsin mutants found in patients with autosomal dominant retinitis pigmentosa.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19971209

Title: Active site-directed inactivation of constitutively active mutants of rhodopsin.

Journal: The Journal of biological chemistry 19940304

Title: Virucidal activity of retinal.

Journal: Antimicrobial agents and chemotherapy 19790901

Title: Photoreceptor protein from the purple membrane of Halobacterium halobium. Molecular weight and retinal binding site.

Journal: Biochemistry 19760224

Title: Biochemical aspects of the visual process. XXXI. Chemical modification studies on rod outer segment retinol dehydrogenase.

Journal: Experimental eye research 19751201

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Tags:564-87-4 Molecular Formula|564-87-4 MDL|564-87-4 SMILES|564-87-4 11-cis Retinal