Catalog No.:AA00F2W4

61-90-5 | L-Leucine

Name: Name:L-Leucine
Brand: AABLOCKS
SKU: AA00F2W4
Availability: InStock
Rating: 90 (10 reviews)

Pack Size

Purity

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Price(USD)

Quantity

25g

97%

in stock

$6.00 $4.00

- +

100g

97%

in stock

$7.00 $5.00

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500g

97%

in stock

$33.00 $23.00

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Technical Information
Properties
Upstream Synthesis Route
Downstream Synthesis Route
Literature
Request for Quotation
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Technical Information
Properties
Upstream Synthesis Route
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA00F2W4

Chemical Name:

L-Leucine

CAS Number:

61-90-5

Molecular Formula:

C6H13NO2

Molecular Weight:

131.1729

MDL Number:

MFCD00002617

SMILES:

N[C@H](C(=O)O)CC(C)C

NSC Number:

760100

FEMA Number:

3297

Properties

BP:

225.8°C at 760 mmHg

Form:

Solid

MP:

>300 °C(lit.)

Refractive Index:

1.4630 (estimate)

Solubility:

1 M HCl: 50 mg/mL

Storage:

Inert atmosphere;Room Temperature;

Computed Properties

Complexity:

101

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

-1.5

Upstream Synthesis Route

61-90-5

57-13-6

67337-73-9

[1]AnnalidiChimica(Rome,Italy),1958,vol.48,p.1199,1202

75-44-5

61-90-5

3190-70-3

[1]AdvancedSynthesisandCatalysis,2004,vol.346,#9-10,p.1247-1249

[2]Patent:US2008/274173,2008,A1,.Locationinpatent:Page/Pagecolumn94

[3]JournaloftheChemicalSociety,1950,p.3222,3225

[4]Patent:US2789973,1950,,

[5]NipponKagakuZasshi,1956,vol.77,p.44,46

[6]Chem.Abstr.,1958,p.258

[7]BulletinoftheChemicalSocietyofJapan,1956,vol.29,p.654,658

[8]Chem.Abstr.,1958,p.258

[9]JournaloftheChemicalSociety,1950,p.3461,3465

[10]Synthesis,1984,#3,p.271-274

[11]LiebigsAnnalenderChemie,1983,#7,p.1133-1151

[12]TetrahedronLetters,2004,vol.45,#26,p.5065-5067

[13]Patent:WO2006/27788,2006,A1,.Locationinpatent:Page/Pagecolumn6

[14]Patent:US2789973,1950,,

61-90-5

503-38-8

3190-70-3

[1]JournalofOrganicChemistry,1985,vol.50,#5,p.715-716

[2]AdvancedSynthesisandCatalysis,2010,vol.352,#13,p.2159-2165

[3]SyntheticCommunications,2017,vol.47,#1,p.53-61

[4]OrganicProcessResearchandDevelopment,2005,vol.9,#6,p.757-763

[5]ChemicalCommunications,2017,vol.53,#37,p.5099-5102

[6]Patent:US5602118,1997,A,

[7]GreenChemistry,2018,vol.20,#6,p.1262-1269

61-90-5

32315-10-9

3190-70-3

[1]CarbohydratePolymers,2010,vol.80,#3,p.885-890

[2]ChemicalCommunications,2015,vol.51,#86,p.15645-15648

[3]OrganicLetters,2017,vol.19,#13,p.3544-3547

[4]TetrahedronLetters,2000,vol.41,#44,p.8615-8619

[5]Biomacromolecules,2010,vol.11,#1,p.60-67

[6]JournalofPolymerScience,PartA:PolymerChemistry,2011,vol.49,#1,p.286-292

[7]Polymer,2011,vol.52,#16,p.3580-3586

[8]Small,2015,vol.11,#21,p.2543-2554

61-90-5

3190-70-3

[1]Patent:US4946942,1990,A,

[2]Patent:US5028693,1991,A,

[3]Patent:US5028693,1991,A,

[4]JournalofOrganicChemistry,1992,vol.57,#28,p.7334-7338

[5]Tetrahedron,1983,vol.39,#9,p.1635-1642

[6]BulletinoftheChemicalSocietyofJapan,1939,vol.14,p.510,512

Downstream Synthesis Route

75-44-5

61-90-5

3190-70-3

[1]AdvancedSynthesisandCatalysis,2004,vol.346,p.1247-1249

[2]Patent:US2008/274173,2008,A1.Locationinpatent:Page/Pagecolumn94

[3]JournaloftheChemicalSociety,1950,p.3222,3225

[4]Synthesis,1984,p.271-274

[5]LiebigsAnnalenderChemie,1983,p.1133-1151

[6]TetrahedronLetters,2004,vol.45,p.5065-5067

[7]Patent:WO2006/27788,2006,A1.Locationinpatent:Page/Pagecolumn6

[8]Patent:US2789973,1950,

61-90-5

28659-87-2

[1]ChemischeBerichte,1907,vol.40,p.491

[2]Patent:WO2005/75471,2005,A2.Locationinpatent:Page/Pagecolumn150-151

[3]Patent:US6194451,2001,B1

[4]JournaloftheAmericanChemicalSociety,2014,vol.136,p.17869-17881

61-90-5

1234-35-1

1188-24-5

[1]JournaloftheAmericanChemicalSociety,1971,vol.93,p.2746-2754

50-00-0

55977-10-1

61-90-5

(S)-2-(3-Bromo-7-hydroxy-4-methyl-2-oxo-2H-chromen-8-ylmethyl)-amino-4-methyl-pentanoicacid

[1]IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1993,vol.32,p.679-680

5699-54-7

61-90-5

[1]JournaloftheChemicalSociety.Chemicalcommunications,1981,p.80-82

Literature

Title: Baoshan Xu, et al. Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet. 2013;9(10):e1003857.

Title: Bruckbauer A, et al. Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice. Nutr Metab (Lond). 2012 Aug 22;9(1):77.

Title: Rachdi L, et al. L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway. Diabetes. 2012 Feb;61(2):409-17.

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SDS