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883050-24-6,MFCD00113783
Catalog No.:AA00H08G

883050-24-6 | Ccg 50014

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$16.00   $11.00
- +
5mg
98%
in stock  
$45.00   $32.00
- +
10mg
98%
in stock  
$66.00   $47.00
- +
25mg
98%
in stock  
$112.00   $78.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00H08G
Chemical Name:
Ccg 50014
CAS Number:
883050-24-6
Molecular Formula:
C16H13FN2O2S
Molecular Weight:
316.3500
MDL Number:
MFCD00113783
SMILES:
Cc1ccc(cc1)n1sc(=O)n(c1=O)Cc1ccc(cc1)F
Properties
Computed Properties
 
Complexity:
432  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.5  

Downstream Synthesis Route
107-03-9    883050-24-6   
C19H21FN2O2S2 

[1]ACSMedicinalChemistryLetters,2012,vol.3,p.146-150

[2]Patent:US2012/277273,2012,A1.Locationinpatent:Page/Pagecolumn37-38

[1]ACSMedicinalChemistryLetters,2012,vol.3,p.146-150

[2]Patent:US2012/277273,2012,A1.Locationinpatent:Page/Pagecolumn22-23

Literature

Title: Inhibition of mycobacterial alanine racemase activity and growth by thiadiazolidinones.

Journal: Biochemical pharmacology 20130715

Title: Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins.

Journal: ACS medicinal chemistry letters 20120209

Title: A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins.

Journal: Biochemistry 20110419

Title: Blazer LL, et al. A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins. Biochemistry. 2011 Apr 19;50(15):3181-92.

Title: Yoon SY, et al. Intrathecal RGS4 inhibitor, CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test. Anesth Analg. 2015 Mar;120(3):671-7.

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SDS
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Tags:883050-24-6 Molecular Formula|883050-24-6 MDL|883050-24-6 SMILES|883050-24-6 Ccg 50014
Catalog No.: AA00H08G
883050-24-6,MFCD00113783
883050-24-6 | Ccg 50014
Pack Size： 1mg
Purity： 98%
in stock
$16.00 $11.00
Pack Size： 5mg
Purity： 98%
in stock
$45.00 $32.00
Pack Size： 10mg
Purity： 98%
in stock
$66.00 $47.00
Pack Size： 25mg
Purity： 98%
in stock
$112.00 $78.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00H08G
Chemical Name: Ccg 50014
CAS Number: 883050-24-6
Molecular Formula: C16H13FN2O2S
Molecular Weight: 316.3500
MDL Number: MFCD00113783
SMILES: Cc1ccc(cc1)n1sc(=O)n(c1=O)Cc1ccc(cc1)F
Properties
Complexity: 432  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 22  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 0  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.5  
Downstream Synthesis Route
107-03-9    883050-24-6   
C19H21FN2O2S2 

[1]ACSMedicinalChemistryLetters,2012,vol.3,p.146-150

[2]Patent:US2012/277273,2012,A1.Locationinpatent:Page/Pagecolumn37-38

2740-88-7    622-58-2    883050-24-6 

[1]ACSMedicinalChemistryLetters,2012,vol.3,p.146-150

[2]Patent:US2012/277273,2012,A1.Locationinpatent:Page/Pagecolumn22-23

Literature fold

Title: Inhibition of mycobacterial alanine racemase activity and growth by thiadiazolidinones.

Journal: Biochemical pharmacology20130715

Title: Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins.

Journal: ACS medicinal chemistry letters20120209

Title: A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins.

Journal: Biochemistry20110419

Title: Blazer LL, et al. A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins. Biochemistry. 2011 Apr 19;50(15):3181-92.

Title: Yoon SY, et al. Intrathecal RGS4 inhibitor, CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test. Anesth Analg. 2015 Mar;120(3):671-7.

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