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51298-62-5,MFCD00039052
Catalog No.:AA00I943

51298-62-5 | H-Arg(NO2)-OMe HCl

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
95%
in stock  
$18.00   $13.00
- +
5g
95%
in stock  
$24.00   $17.00
- +
10g
98%
in stock  
$33.00   $23.00
- +
25g
95%
in stock  
$70.00   $49.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I943
Chemical Name:
H-Arg(NO2)-OMe HCl
CAS Number:
51298-62-5
Molecular Formula:
C7H16ClN5O4
Molecular Weight:
269.6860
MDL Number:
MFCD00039052
SMILES:
COC(=O)[C@H](CCCNC(=N)N[N+](=O)[O-])N.Cl
Properties
Properties
 
BP:
383.5°C at 760 mmHg  
Form:
Solid  
MP:
157-161 °C  
Refractive Index:
15 ° (C=3, MeOH)  
Solubility:
H2O: 50 mg/mL  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
274  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
7  

Literature

Title: Discovery of N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl) thiophene-2-carboximidamide as a selective inhibitor of human neuronal nitric oxide synthase (nNOS) for the treatment of pain.

Journal: Journal of medicinal chemistry 20111027

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Pfeiffer S, et al. Inhibition of nitric oxide synthesis by NG-nitro-L-arginine methyl ester (L-NAME): requirement forbioactivation to the free acid, NG-nitro-L-arginine. Br J Pharmacol. 1996 Jul;118(6):1433-40.

Title: Kopincová J, et al. L-NAME in the cardiovascular system - nitric oxide synthase activator? Pharmacol Rep. 2012;64(3):511-20.

Title: Lo HC, et al. The Nitric Oxide Synthase Inhibitor NG-Nitro-L-Arginine Methyl Ester Diminishes the Immunomodulatory Effects of Parental Arginine in Rats with Subacute Peritonitis. PLoSOne. 2016 Mar 23;11(3):e0151973.

Title: Luo H, et al. Effect of nitric oxide synthase inhibitor L-NAME on fear extinction in rats: a task-dependent effect. Neurosci Lett. 2014 Jun 20;572:13-8.

Title: Ocsan RJ, et al. Chronic NG-nitro-l-arginine methyl ester (L-NAME) administration in C57BL/6J mice induces a sustained decrease in c-kit positive cells during development of cardiac hypertrophy. J Physiol Pharmacol. 2013 Dec;64(6):727-36.

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