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99592-39-9,MFCD00918063
Catalog No.:AA00IK8L

99592-39-9 | 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole; nitric acid

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25mg
95%
in stock  
$32.00   $23.00
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100mg
95%
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$80.00   $56.00
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1g
95%
in stock  
$151.00   $106.00
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5g
95%
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$604.00   $423.00
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10g
95%
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$1,080.00   $756.00
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25g
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$1,905.00   $1,334.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IK8L
Chemical Name:
1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole; nitric acid
CAS Number:
99592-39-9
Molecular Formula:
C20H16Cl3N3O4S
Molecular Weight:
500.7827
MDL Number:
MFCD00918063
SMILES:
Clc1ccc(c(c1)Cl)C(Cn1ccnc1)OCc1csc2c1cccc2Cl.[O-][N+](=O)O
Properties
Computed Properties
 
Complexity:
513  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Why are most phospholipidosis inducers also hERG blockers?

Journal: Archives of toxicology 20171201

Title: Treatment of interdigital tinea pedis: once-daily therapy with sertaconazole nitrate.

Journal: Journal of drugs in dermatology : JDD 20111001

Title: An open-label study of the safety and efficacy of sertaconazole nitrate in the treatment of seborrheic dermatitis.

Journal: Journal of drugs in dermatology : JDD 20110801

Title: Efficacy and tolerability of sertaconazole nitrate 2% cream vs. miconazole in patients with cutaneous dermatophytosis.

Journal: Mycoses 20110501

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Induction of prostaglandin D2 through the p38 MAPK pathway is responsible for the antipruritic activity of sertaconazole nitrate.

Journal: The Journal of investigative dermatology 20101001

Title: Safety and efficacy of sertaconazole nitrate cream 2% in the treatment of tinea pedis interdigitalis: a subgroup analysis.

Journal: Cutis 20100201

Title: Sertaconazole 2% cream vs. miconazole 2% cream for cutaneous mycoses: a double-blind clinical trial.

Journal: Clinical and experimental dermatology 20091201

Title: A validated LC-MS/MS method for determination of sertaconazole nitrate in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091201

Title: What is your diagnosis? Tinea nigra.

Journal: Cutis 20091201

Title: Observational evaluation of sertaconazole nitrate cream 2% in the treatment of pruritus related to tinea pedis.

Journal: Cutis 20091101

Title: Safe and effective treatment of seborrheic dermatitis.

Journal: Cutis 20090601

Title: Sertaconazole nitrate cream 2% for the treatment of tinea pedis.

Journal: Cutis 20090501

Title: Sertaconazole: a review of its use in the management of superficial mycoses in dermatology and gynaecology.

Journal: Drugs 20090101

Title: Widespread, chronic, and fluconazole-resistant Trichophyton rubrum infection in an immunocompetent patient.

Journal: Mycoses 20081101

Title: In vitro antifungal activity of sertaconazole nitrate against recent isolates of onychomycosis causative agents.

Journal: Journal of chemotherapy (Florence, Italy) 20080801

Title: Comprehensive management of patients with superficial fungal infections: the role of sertaconazole nitrate.

Journal: Cutis 20080601

Title: Anti-inflammatory activity of sertaconazole nitrate is mediated via activation of a p38-COX-2-PGE2 pathway.

Journal: The Journal of investigative dermatology 20080201

Title: Comparative study of 2% sertaconazole solution and cream formulations in patients with tinea corporis, tinea pedis interdigitalis, or a corresponding candidosis.

Journal: American journal of clinical dermatology 20070101

Title: Review of in vitro activity of sertaconazole nitrate in the treatment of superficial fungal infections.

Journal: Diagnostic microbiology and infectious disease 20061001

Title: The safety and efficacy of sertaconazole nitrate cream 2% for tinea pedis.

Journal: Cutis 20061001

Title: Anti-inflammatory and anti-itch activity of sertaconazole nitrate.

Journal: Archives of dermatological research 20060901

Title: Sertaconazole/hydroxypropyl-beta-cyclodextrin complexation: isothermal titration calorimetry and solubility approaches.

Journal: Journal of pharmaceutical sciences 20060801

Title: Single-dose sertaconazole vaginal tablet treatment of vulvovaginal candidiasis.

Journal: Journal of the Chinese Medical Association : JCMA 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Nail penetration of sertaconazole with a sertaconazole-containing nail patch formulation.

Journal: American journal of clinical dermatology 20060101

Title: Drug solubilization and delivery from cyclodextrin-Pluronic aggregates.

Journal: Journal of nanoscience and nanotechnology 20060101

Title: Sertaconazole: updated review of a topical antifungal agent.

Journal: Expert review of anti-infective therapy 20050601

Title: Rate and extent of percutaneous absorption of sertaconazole nitrate after topical administration.

Journal: Arzneimittel-Forschung 20050101

Title: In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis.

Journal: Chemotherapy 20041201

Title: Topical sertaconazole (ertaczo)--another azole for tinea pedis.

Journal: The Medical letter on drugs and therapeutics 20040621

Title: In vitro antifungal activity of sertaconazole against 309 dermatophyte clinical isolates.

Journal: Journal of chemotherapy (Florence, Italy) 20031201

Title: In vitro activity of sertaconazole against dermatophyte isolates with reduced fluconazole susceptibility.

Journal: Chemotherapy 20030901

Title: Effect of cyclodextrins on the solubility and antimycotic activity of sertaconazole: experimental and computational studies.

Journal: Journal of pharmaceutical sciences 20021101

Title: Corneal ulcer caused by the new fungal species Sarcopodium oculorum.

Journal: Journal of clinical microbiology 20020801

Title: Sertaconazole: in-vitro antifungal activity against vaginal and other superficial yeast isolates.

Journal: Journal of chemotherapy (Florence, Italy) 20011001

Title: In vitro activity of sertaconazole, fluconazole, ketoconazole, fenticonazole, clotrimazole and itraconazole against pathogenic vaginal yeast isolates.

Journal: Methods and findings in experimental and clinical pharmacology 20010301

Title: Comparative study of antifungal activity of sertaconazole, terbinafine, and bifonazole against clinical isolates of Candida spp., Cryptococcus neoformans and dermatophytes.

Journal: Chemotherapy 19970101

Title: Antifungal activity of sertaconazole in vitro against clinical isolates of Candida spp.

Journal: Chemotherapy 19960101

Title: In-vitro antifungal activity of sertaconazole, econazole, and bifonazole against Candida spp.

Journal: The Journal of antimicrobial chemotherapy 19951001

Title: In vitro activity of sertaconazole.

Journal: Arzneimittel-Forschung 19920501

Title: In vitro antifungal activity of sertaconazole.

Journal: Arzneimittel-Forschung 19920501

Title: In vitro comparative study of the fungistatic and fungicidal activity of sertaconazole and other antifungals against Candida albicans.

Journal: Arzneimittel-Forschung 19920501

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Tags:99592-39-9 Molecular Formula|99592-39-9 MDL|99592-39-9 SMILES|99592-39-9 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole; nitric acid