Home Amines 51-78-5
51-78-5,MFCD00012996
Catalog No.:AA00ILE9

51-78-5 | 4-Aminophenol hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25g
>98.0%(HPLC)(N)
in stock  
$75.00   $52.00
- +
100g
>98.0%(HPLC)(N)
in stock  
$230.00   $161.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ILE9
Chemical Name:
4-Aminophenol hydrochloride
CAS Number:
51-78-5
Molecular Formula:
C6H8ClNO
Molecular Weight:
145.5868
MDL Number:
MFCD00012996
SMILES:
Oc1ccc(cc1)[NH3+].[Cl-]
Properties
Properties
 
Form:
Solid  
MP:
302 °C  

Computed Properties
 
Complexity:
66.9  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
3  

Literature

Title: In vitro safety assessment of food ingredients in canine renal proximal tubule cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20150301

Title: Facile synthesis of highly dispersed palladium/polypyrrole nanocapsules for catalytic reduction of p-nitrophenol.

Journal: Journal of colloid and interface science 20120801

Title: Highly sensitive sequential injection determination of p-aminophenol in paracetamol formulations with 18-molybdodiphosphate heteropoly anion based on elimination of Schlieren effect.

Journal: Talanta 20120715

Title: Simultaneous spectrophotometric determination of paracetamol and para-aminophenol in pharmaceutical dosage forms using two novel multivariate standard addition methods based on net analyte signal and rank annihilation factor analysis.

Journal: Drug testing and analysis 20120601

Title: A Pt layer/Pt disk electrode configuration to evaluate respiration and alkaline phosphatase activities of mouse embryoid bodies.

Journal: Talanta 20120530

Title: Separation and electrochemical detection of paracetamol and 4-aminophenol in a paper-based microfluidic device.

Journal: Analytica chimica acta 20120506

Title: A manganese oxide with phenol groups as a promising structural model for water oxidizing complex in Photosystem II: a 'golden fish'.

Journal: Dalton transactions (Cambridge, England : 2003) 20120414

Title: Production of p-acetaminophenol by whole-cell catalysis using Escherichia coli overexpressing bacterial aryl acylamidase.

Journal: Biotechnology letters 20120401

Title: p-Aminophenol-induced cytotoxicity in Jurkat T cells: protective effect of 2(RS)-n-propylthiazolidine-4(R)-carboxylic acid.

Journal: Journal of biochemical and molecular toxicology 20120201

Title: 'Outer-sphere to inner-sphere' redox cycling for ultrasensitive immunosensors.

Journal: Analytical chemistry 20120117

Title: p-Aminophenol and p-paraphenylenediamine induce injury and apoptosis of human HK-2 proximal tubular epithelial cells.

Journal: Journal of nephrology 20120101

Title: Microbially supported synthesis of catalytically active bimetallic Pd-Au nanoparticles.

Journal: Biotechnology and bioengineering 20120101

Title: Highly-sensitive electrochemical immunosensing method based on dual amplification systems.

Journal: Biosensors & bioelectronics 20120101

Title: Catalytic reduction of 4-nitrophenol using biogenic gold and silver nanoparticles derived from Breynia rhamnoides.

Journal: Langmuir : the ACS journal of surfaces and colloids 20111220

Title: Facile synthesis of two-dimensional graphene/SnO₂ /Pt ternary hybrid nanomaterials and their catalytic properties.

Journal: Nanoscale 20111005

Title: Simultaneous determination of N-acetyl-p-aminophenol and p-aminophenol with poly(3,4-ethylenedioxythiophene) modified glassy carbon electrode.

Journal: Talanta 20110915

Title: Aqueous two-phase systems: a new approach for the determination of p-aminophenol.

Journal: Journal of hazardous materials 20110815

Title: High-sensitivity electrochemical enzyme-linked assay on a microfluidic interdigitated microelectrode.

Journal: Biosensors & bioelectronics 20110715

Title: A graphene-based Au(111) platform for electrochemical biosensing based catalytic recycling of products on gold nanoflowers.

Journal: The Analyst 20110607

Title: Nanoband electrode for high-performance in-channel amperometric detection in dual-channel microchip capillary electrophoresis.

Journal: Electrophoresis 20110401

Title: Enzyme-free electrochemical immunoassay with catalytic reduction of p-nitrophenol and recycling of p-aminophenol using gold nanoparticles-coated carbon nanotubes as nanocatalysts.

Journal: Biosensors & bioelectronics 20110315

Title: Electrochemical detection of quorum sensing signaling molecules by dual signal confirmation at microelectrode arrays.

Journal: Analytical chemistry 20110315

Title: Redox cycling amplified electrochemical detection of DNA hybridization: application to pathogen E. coli bacterial RNA.

Journal: Analytica chimica acta 20110309

Title: Acute toxicity and mutagenesis of three metabolites mixture of nitrobenzene in mice.

Journal: Toxicology and industrial health 20110301

Title: Fe-superoxide dismutase and 2-hydroxy-1,4-benzoquinone reductase preclude the auto-oxidation step in 4-aminophenol metabolism by Burkholderia sp. strain AK-5.

Journal: Biodegradation 20110201

Title: Porous, catalytically active palladium nanostructures by tuning nanoparticle interactions in an organic medium.

Journal: Nanoscale 20110201

Title: A voltammetric sensor for the simultaneous determination of L-cysteine and tryptophan using a p-aminophenol-multiwall carbon nanotube paste electrode.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101

Title: Light triggered detection of aminophenyl phosphate with a quantum dot based enzyme electrode.

Journal: Journal of nanobiotechnology 20110101

Title: Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety.

Journal: PloS one 20110101

Title: p-Aminophenol-multiwall carbon nanotubes-TiO2 electrode as a sensor for simultaneous determination of penicillamine and uric acid.

Journal: Colloids and surfaces. B, Biointerfaces 20101101

Title: Low-temperature co-fired ceramic microchannels with individually addressable screen-printed gold electrodes on four walls for self-contained electrochemical immunoassays.

Journal: Analytical and bioanalytical chemistry 20101101

Title: Synthesis of new azo compounds based on N-(4-hydroxypheneyl)maleimide and N-(4-methylpheneyl)maleimide.

Journal: Molecules (Basel, Switzerland) 20101025

Title: An electrochemical enzyme bioaffinity electrode based on biotin-streptavidin conjunction and bienzyme substrate recycling for amplification.

Journal: Analytical biochemistry 20101001

Title: Amperometric detection of Enterobacteriaceae in river water by measuring β-galactosidase activity at interdigitated microelectrode arrays.

Journal: Analytica chimica acta 20100916

Title: Synthesis of self-supporting gold microstructures with three-dimensional morphologies by direct replication of diatom templates.

Journal: Langmuir : the ACS journal of surfaces and colloids 20100907

Title: Redox-magnetohydrodynamic microfluidics without channels and compatible with electrochemical detection under immunoassay conditions.

Journal: Analytical chemistry 20100901

Title: Four-week oral toxicity study of three metabolites of nitrobenzene in rats.

Journal: Drug and chemical toxicology 20100701

Title: Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis.

Journal: Chemistry & biology 20100528

Title: A greener and highly sensitive flow-based procedure for carbaryl determination exploiting long pathlength spectrophotometry and photochemical waste degradation.

Journal: Talanta 20100415

Title: Diffusion and reaction in microbead agglomerates.

Journal: Analytical chemistry 20100401

Title: Photochemical green synthesis of calcium-alginate-stabilized Ag and Au nanoparticles and their catalytic application to 4-nitrophenol reduction.

Journal: Langmuir : the ACS journal of surfaces and colloids 20100216

Title: Integrated microfluidic magnetic immunosensor for quantification of human serum IgG antibodies to Helicobacter pylori.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100115

Title: The role of para-aminophenol in acetaminophen-induced methemoglobinemia in dogs and cats.

Journal: Journal of veterinary pharmacology and therapeutics 20091201

Title: Reduction of nitro phenols using nitroreductase from E. coli in the presence of NADH.

Journal: Journal of hazardous materials 20091015

Title: Multiple-point electrochemical detection for a dual-channel hybrid PDMS-glass microchip electrophoresis device.

Journal: Electrophoresis 20091001

Title: Dermal penetration and metabolism of p-aminophenol and p-phenylenediamine: application of the EpiDerm human reconstructed epidermis model.

Journal: Toxicology letters 20090724

Title: Oxidative carbon-carbon bond formation in the synthesis of bioactive spiro beta-lactams.

Journal: Organic letters 20090702

Title: Fast electrochemical detection of anti-HIV antibodies: coupling allosteric enzymes and disk microelectrode arrays.

Journal: Analytica chimica acta 20090508

Title: Permeation of hair dye ingredients, p-phenylenediamine and aminophenol isomers, through protective gloves.

Journal: The Annals of occupational hygiene 20090401

Title: Electrochemical gene-function analysis for single cells with addressable microelectrode/microwell arrays.

Journal: Angewandte Chemie (International ed. in English) 20090101

Title: Structure analysis of aromatic medicines containing nitrogen using near-infrared spectroscopy and generalized two-dimensional correlation spectroscopy.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081215

Title: An electrochemical immunosensor using p-aminophenol redox cycling by NADH on a self-assembled monolayer and ferrocene-modified Au electrodes.

Journal: The Analyst 20081101

Title: Immuno-column for on-line quantification of human serum IgG antibodies to Helicobacter pylori in human serum samples.

Journal: Talanta 20080915

Title: Contribution of reactive oxygen species to para-aminophenol toxicity in LLC-PK1 cells.

Journal: Toxicology and applied pharmacology 20080715

Title: Multiwalled carbon nanotube modified screen-printed electrodes for the detection of p-aminophenol: optimisation and application in alkaline phosphatase-based assays.

Journal: Analytica chimica acta 20080512

Title: Validation of a fluorimetric assay for 4-aminophenol in paracetamol formulations.

Journal: Talanta 20080315

Title: A sensitive spectrophotometric method for the determination of H2-receptor antagonists by means of N-bromosuccinimide and p-aminophenol.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20080301

Title: Rapid determination of acetaminophen and p-aminophenol in pharmaceutical formulations using miniaturized capillary electrophoresis with amperometric detection.

Journal: Analytica chimica acta 20080114

Title: Reproductive and developmental toxicity screening study of 4-aminophenol in rats.

Journal: Drug and chemical toxicology 20080101

Title: Separation and analysis of trace degradants in a pharmaceutical formulation using on-line capillary isotachophoresis-NMR.

Journal: Analytical chemistry 20071115

Title: A catalytically active molecularly imprinted polymer that mimics peroxidase based on hemin: application to the determination of p-aminophenol.

Journal: Analytical and bioanalytical chemistry 20071101

Title: Cisplatin, gentamicin, and p-aminophenol induce markers of endoplasmic reticulum stress in the rat kidneys.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070901

Title: Calpain inhibition but not reticulum endoplasmic stress preconditioning protects rat kidneys from p-aminophenol toxicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070901

Title: Comparison of 2-aminophenol and 4-nitrophenol as in vitro probe substrates for the major human hepatic sulfotransferase, SULT1A1, demonstrates improved selectivity with 2-aminophenol.

Journal: Biochemical pharmacology 20070715

Title: Theoretical studies on electrochemistry of p-aminophenol.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070701

Title: p-Aminophenol degradation by ozonation combined with sonolysis: operating conditions influence and mechanism.

Journal: Ultrasonics sonochemistry 20070701

Title: Electron paramagnetic resonance analyses of biotransformation reactions with cytochrome P-450 immobilized on mesoporous molecular sieves.

Journal: Biotechnology letters 20070601

Title: Clinicopathological and tissue indicators of para-aminophenol nephrotoxicity in sprague-dawley rats.

Journal: Toxicologic pathology 20070601

Title: Ozonation of aniline promoted by activated carbon.

Journal: Chemosphere 20070301

Title: Simultaneous determination of paracetamol, chlorzoxazone, and related impurities 4-aminophenol, 4'-chloroacetanilide, and p-chlorophenol in pharmaceutical preparations by high-performance liquid chromatography.

Journal: Journal of AOAC International 20070101

Title: Catalytic properties of carboxylic acid functionalized-polymer microsphere-stabilized gold metallic colloids.

Journal: Journal of colloid and interface science 20061201

Title: Effects of lipoic acid and dihydrolipoic acid on 4-aminophenol-mediated erythrocytic toxicity in vitro.

Journal: Basic & clinical pharmacology & toxicology 20060901

Title: Unconsumed precursors and couplers after formation of oxidative hair dyes.

Journal: Contact dermatitis 20060801

Title: Pyruvate reduces 4-aminophenol in vitro toxicity.

Journal: Toxicology and applied pharmacology 20060601

Title: Spectrophotometric determination of paracetamol in urine with tetrahydroxycalix[4]arene as a coupling reagent and preconcentration with triton X-114 using cloud point extraction.

Journal: Chemical & pharmaceutical bulletin 20060601

Title: Plasma/blood pharmacokinetics and metabolism after dermal exposure to para-aminophenol or para-phenylenediamine.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060301

Title: Time-dependent effect of p-aminophenol (PAP) toxicity in renal slices and development of oxidative stress.

Journal: Toxicology and applied pharmacology 20051115

Title: New prodrugs derived from 6-aminodopamine and 4-aminophenol as candidates for melanocyte-directed enzyme prodrug therapy (MDEPT).

Journal: Organic & biomolecular chemistry 20051107

Title: Under the skin: Biotransformation of para-aminophenol and para-phenylenediamine in reconstructed human epidermis and human hepatocytes.

Journal: Toxicology letters 20050915

Title: Migration behaviour and separation of acetaminophen and p-aminophenol in capillary zone electrophoresis: analysis of drugs based on acetaminophen.

Journal: Journal of pharmaceutical and biomedical analysis 20050601

Title: Comparison of para-aminophenol cytotoxicity in rat renal epithelial cells and hepatocytes.

Journal: Toxicology 20050401

Title: Spectrofluorimetric determination of acetaminophen with N-bromosuccinimide.

Journal: Journal of AOAC International 20050101

Title: Toxic effects of aminophenols on aquatic life using the zebrafish embryo test and the comet assay.

Journal: Bulletin of environmental contamination and toxicology 20041001

Title: The demonstration of an enhanced microelectrochemical transistor for measurements in neutral solution at low analyte concentration.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20040801

Title: The measurement of alkaline phosphatase at nanomolar concentration within 70 s using a disposable microelectrochemical transistor.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20040801

Title: Bead-based immunoassays with microelectrode detection.

Journal: Analytical and bioanalytical chemistry 20040601

Title: Enzyme-amplified electrochemical detection of DNA using electrocatalysis of ferrocenyl-tethered dendrimer.

Journal: Analytical chemistry 20031101

Title: Aromatic amines and biomarkers of human exposure.

Journal: Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews 20031101

Title: Determination of 4-aminophenol impurities in multicomponent analgesic preparations by HPLC with amperometric detection.

Journal: Journal of pharmaceutical and biomedical analysis 20030808

Title: A potential biomarker of kidney damage identified by proteomics: preliminary findings.

Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101

Title: Biological activity of p-methylaminophenol, an essential structural component of N-(4-hydroxyphenyl)retinamide, fenretinide.

Journal: Journal of biochemistry 20021101

Title: Deviceless decoupled electrochemical detection of catecholamines in capillary electrophoresis using gold microband array electrodes.

Journal: Electrophoresis 20021101

Title: NMR and Bayesian regularized neural network regression for impurity determination of 4-aminophenol.

Journal: Journal of pharmaceutical and biomedical analysis 20020701

Title: Cytokinin oxidase/cytokinin dehydrogenase assay: optimized procedures and applications.

Journal: Analytical biochemistry 20020701

Title: [Research into simultaneous spectrophotometric determination of components in cough syrup by principal component regression method].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20020601

Title: Cross-sensitization to haptens: formation of common haptenic metabolites, T cell recognition of cryptic peptides, and true T cell cross-reactivity.

Journal: European journal of immunology 20020501

Title: The spectrum of allergic (cross-)sensitivity in clinical patch testing with 'para amino' compounds.

Journal: Allergy 20020401

Title: Determination of 4-aminophenol using the quartz crystal microbalance sensor.

Journal: The Analyst 20020301

Title: Renal PGE2 production in the human and rat following phenacetin, acetaminophen and p-aminophenol.

Journal: Research communications in molecular pathology and pharmacology 20020101

Title: Contact anaphylaxis due to para-aminophenol and para-methylaminophenol in hair dye.

Journal: Contact dermatitis 20011201

Title: Metabolism of (R)- and (S)-3-(phenylamino)propane-1,2-diol in C57BL/6- and A/J-strain mice. Identification of new metabolites with potential toxicological significance to the toxic oil syndrome.

Journal: Chemical research in toxicology 20010801

Title: p-Aminophenol-induced liver toxicity: tentative evidence of a role for acetaminophen.

Journal: Journal of biochemical and molecular toxicology 20010101

Title: Determination of 4-aminophenol impurities in selected pharmaceutical preparations by HPLC method with amperometric detection.

Journal: Acta poloniae pharmaceutica 20010101

Title: Isolation and characterization of a pseudomonas strain that degrades 4-acetamidophenol and 4-aminophenol.

Journal: Biodegradation 20010101

Title: Metabonomics: evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20001001

Title: Genotoxic effects of p-aminophenol in Chinese hamster ovary and mouse lymphoma cells: results of a multiple endpoint test.

Journal: Environmental and molecular mutagenesis 19950101

Title: Studies on the mechanism of 4-aminophenol-induced toxicity to renal proximal tubules.

Journal: Human & experimental toxicology 19930901

Title: Studies on the effects of L(alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) on 4-aminophenol-induced nephrotoxicity in the Fischer 344 rat.

Journal: Archives of toxicology 19930101

Title: Nephrotoxicity of 4-aminophenol glutathione conjugate.

Journal: Human & experimental toxicology 19911101

Title: Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse.

Journal: Toxicology and applied pharmacology 19910101

Title: Study on cross-reactivity to the para group.

Journal: Dermatologica 19900101

Title: Urinalysis for detection of chemically induced renal damage (2)--Changes in urinary excretions of enzymes and various components caused by p-aminophenol, puromycin aminonucleoside and hexadimethrine.

Journal: The Journal of toxicological sciences 19871101

Title: The role of p-aminophenol in acetaminophen-induced nephrotoxicity: effect of bis(p-nitrophenyl) phosphate on acetaminophen and p-aminophenol nephrotoxicity and metabolism in Fischer 344 rats.

Journal: Toxicology and applied pharmacology 19851201

Title: Incorporation of chorismic acid and 4-aminobenzoic acid into the 4-hydroxyaniline moiety of N-(gamma-L-glutamyl)-4-hydroxyaniline in Agaricus bisporus.

Journal: Biochimica et biophysica acta 19850618

Title: Acetaminophen nephrotoxicity in the rat. II. Strain differences in nephrotoxicity and metabolism of p-aminophenol, a metabolite of acetaminophen.

Journal: Toxicology and applied pharmacology 19830630

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:51-78-5 Molecular Formula|51-78-5 MDL|51-78-5 SMILES|51-78-5 4-Aminophenol hydrochloride |Organic_Building_Blocks