Title: Depletion of follicles accelerated by combined exposure to phthalates and 4-vinylcyclohexene diepoxide, leading to premature ovarian failure in rats.
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Journal: Redox biology 20150801
Title: Glutathione S-transferase class μ regulation of apoptosis signal-regulating kinase 1 protein during VCD-induced ovotoxicity in neonatal rat ovaries.
Journal: Toxicology and applied pharmacology 20130215
Title: An update on primary ovarian insufficiency.
Journal: Science China. Life sciences 20120801
Title: Analysis of second-harmonic-generation microscopy in a mouse model of ovarian carcinoma.
Journal: Journal of biomedical optics 20120701
Title: Modeling perimenopause in Sprague-Dawley rats by chemical manipulation of the transition to ovarian failure.
Journal: Comparative medicine 20120601
Title: Decreased bone mineral density in rats rendered follicle-deplete by an ovotoxic chemical correlates with changes in follicle-stimulating hormone and inhibin A.
Journal: Calcified tissue international 20120301
Title: 4-vinylcyclohexene diepoxide: a model chemical for ovotoxicity.
Journal: Systems biology in reproductive medicine 20120201
Title: Ovarian expressed microsomal epoxide hydrolase: role in detoxification of 4-vinylcyclohexene diepoxide and regulation by phosphatidylinositol-3 kinase signaling.
Journal: Toxicology and applied pharmacology 20120101
Title: Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats.
Journal: Biology of reproduction 20111001
Title: Estradiol treatment, physical activity, and muscle function in ovarian-senescent mice.
Journal: Experimental gerontology 20110801
Title: 4-Vinylcyclohexene diepoxide (VCD) inhibits mammary epithelial differentiation and induces fibroadenoma formation in female Sprague Dawley rats.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20110701
Title: Induction of a menopausal state alters the growth and histology of ovarian tumors in a mouse model of ovarian cancer.
Journal: Menopause (New York, N.Y.) 20110501
Title: Inhibition of PIK3 signaling pathway members by the ovotoxicant 4-vinylcyclohexene diepoxide in rats.
Journal: Biology of reproduction 20110401
Title: Accelerated ovarian failure: a novel, chemically induced animal model of menopause.
Journal: Brain research 20110316
Title: Midkine, a heparin-binding protein, is increased in the diabetic mouse kidney postmenopause.
Journal: American journal of physiology. Renal physiology 20110101
Title: Chemotherapy-induced late transgenerational effects in mice.
Journal: PloS one 20110101
Title: 4-Vinyl-1-cyclohexene diepoxide.
Journal: Report on carcinogens : carcinogen profiles 20110101
Title: Strategies and methods to study sex differences in cardiovascular structure and function: a guide for basic scientists.
Journal: Biology of sex differences 20110101
Title: Adding insult to injury: effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101201
Title: Distribution and responsiveness of rat anti-Müllerian hormone during ovarian development and VCD-induced ovotoxicity.
Journal: Toxicology and applied pharmacology 20101115
Title: Experimental induction of reduced ovarian reserve in a nonhuman primate model (Macaca fascicularis).
Journal: Comparative medicine 20101001
Title: Dual protective role for glutathione S-transferase class pi against VCD-induced ovotoxicity in the rat ovary.
Journal: Toxicology and applied pharmacology 20100901
Title: Simultaneous optical coherence tomography and laser induced fluorescence imaging in rat model of ovarian carcinogenesis.
Journal: Cancer biology & therapy 20100901
Title: The cognitive effects of conjugated equine estrogens depend on whether menopause etiology is transitional or surgical.
Journal: Endocrinology 20100801
Title: 7,12-dimethylbenz[a]anthracene induces sertoli-leydig-cell tumors in the follicle-depleted ovaries of mice treated with 4-vinylcyclohexene diepoxide.
Journal: Comparative medicine 20100201
Title: Retaining Residual Ovarian Tissue following Ovarian Failure Has Limited Influence on Bone Loss in Aged Mice.
Journal: Journal of osteoporosis 20100101
Title: A longitudinal study of the effect of genistein on bone in two different murine models of diminished estrogen-producing capacity.
Journal: Journal of osteoporosis 20100101
Title: Effect of phosphatidylinositol-3 kinase inhibition on ovotoxicity caused by 4-vinylcyclohexene diepoxide and 7, 12-dimethylbenz[a]anthracene in neonatal rat ovaries.
Journal: Toxicology and applied pharmacology 20091201
Title: Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090901
Title: Transitional versus surgical menopause in a rodent model: etiology of ovarian hormone loss impacts memory and the acetylcholine system.
Journal: Endocrinology 20090901
Title: Using basic science to design a clinical trial: baseline characteristics of women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS).
Journal: Journal of cardiovascular translational research 20090901
Title: Lactational coumestrol exposure increases ovarian apoptosis in adult rats.
Journal: Archives of toxicology 20090601
Title: Neuroprotection against excitotoxic brain injury in mice after ovarian steroid depletion.
Journal: Brain research 20090410
Title: Ovarian neoplasm development by 7,12-dimethylbenz[a]anthracene (DMBA) in a chemically-induced rat model of ovarian failure.
Journal: Gynecologic oncology 20090301
Title: Steroidogenic capacity of residual ovarian tissue in 4-vinylcyclohexene diepoxide-treated mice.
Journal: Biology of reproduction 20090201
Title: Effects of 4-vinylcyclohexene diepoxide on peripubertal and adult Sprague-Dawley rats: ovarian, clinical, and pathologic outcomes.
Journal: Comparative medicine 20090201
Title: Collaborative work on evaluation of ovarian toxicity. 4) Two- or four-week repeated dose study of 4-vinylcyclohexene diepoxide in female rats.
Journal: The Journal of toxicological sciences 20090101
Title: Collaborative work on evaluation of ovarian toxicity. 4) Effects of fertility study of 4-vinylcyclohexene diepoxide in female rats.
Journal: The Journal of toxicological sciences 20090101
Title: Behavioral consequences of ovarian atrophy and estrogen replacement in the APPswe mouse.
Journal: Neurobiology of aging 20081001
Title: Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081001
Title: Correlation of serum anti-Müllerian hormone with accelerated follicle loss following 4-vinylcyclohexene diepoxide-induced follicle loss in mice.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20081001
Title: Oridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive response.
Journal: Environmental health perspectives 20080901
Title: Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080801
Title: Involvement of the KIT/KITL signaling pathway in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in rats.
Journal: Biology of reproduction 20080801
Title: Expression of ovarian microsomal epoxide hydrolase and glutathione S-transferase during onset of VCD-induced ovotoxicity in B6C3F(1) mice.
Journal: Toxicology and applied pharmacology 20080701
Title: Peer review and reflection continues forever.
Journal: Fertility and sterility 20080401
Title: Development of a sampling and analysis method for 4-vinyl-1-cyclohexene in air.
Journal: Journal of occupational health 20080101
Title: Effects of impending ovarian failure induced by 4-vinylcyclohexene diepoxide on fertility in C57BL/6 female mice.
Journal: Comparative medicine 20071001
Title: Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause.
Journal: American journal of physiology. Renal physiology 20070701
Title: Destruction of primordial ovarian follicles in adult cynomolgus macaques after exposure to 4-vinylcyclohexene diepoxide: a nonhuman primate model of the menopausal transition.
Journal: Fertility and sterility 20061001
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Recent female mouse models displaying advanced reproductive aging.
Journal: Experimental gerontology 20060201
Title: Effect of duration of dosing on onset of ovarian failure in a chemical-induced mouse model of perimenopause.
Journal: Menopause (New York, N.Y.) 20060101
Title: Dual modality imaging of a novel rat model of ovarian carcinogenesis.
Journal: Journal of biomedical optics 20060101
Title: Characterization of cyclicity and hormonal profile with impending ovarian failure in a novel chemical-induced mouse model of perimenopause.
Journal: Comparative medicine 20051201
Title: Atherosclerotic lesion development in a novel ovary-intact mouse model of perimenopause.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050901
Title: Differences between rats and mice in the involvement of the aryl hydrocarbon receptor in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss.
Journal: Toxicology and applied pharmacology 20050301
Title: Initiation of delayed ovotoxicity by in vitro and in vivo exposures of rat ovaries to 4-vinylcyclohexene diepoxide.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20041101
Title: The follicle-deplete mouse ovary produces androgen.
Journal: Biology of reproduction 20040701
Title: 4-Vinyl-1-cyclohexene diepoxide.
Journal: Report on carcinogens : carcinogen profiles 20040101
Title: Expression and activity of cytochromes P450 2E1, 2A, and 2B in the mouse ovary: the effect of 4-vinylcyclohexene and its diepoxide metabolite.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030601
Title: Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene diepoxide exposure of female mice in vivo.
Journal: Endocrinology 20030101
Title: Ovarian follicle counts--not as simple as 1, 2, 3.
Journal: Reproductive biology and endocrinology : RB&E 20030101
Title: In vivo exposure of female rats to toxicants may affect oocyte quality.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20030101
Title: Characterization of a rat in vitro ovarian culture system to study the ovarian toxicant 4-vinylcyclohexene diepoxide.
Journal: Toxicology and applied pharmacology 20021015
Title: Activation of mitogen-activated protein kinases and AP-1 transcription factor in ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats.
Journal: Biology of reproduction 20020901
Title: Expression and activity of microsomal epoxide hydrolase in follicles isolated from mouse ovaries.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020701
Title: 17beta-estradiol affords protection against 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in Fischer-344 rats.
Journal: Endocrinology 20020301
Title: Long-term effects of ovarian follicular depletion in rats by 4-vinylcyclohexene diepoxide.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20020101
Title: 4-Vinyl-1-cyclohexene diepoxide.
Journal: Report on carcinogens : carcinogen profiles 20020101
Title: Expression and redistribution of cellular Bad, Bax, and Bcl-X(L) protein is associated with VCD-induced ovotoxicity in rats.
Journal: Biology of reproduction 20011101
Title: Effect of 4-vinylcyclohexene diepoxide dosing in rats on GSH levels in liver and ovaries.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010801
Title: Evaluation of hepatic cytochrome P4502E1 in the species-dependent bioactivation of 4-vinylcyclohexene.
Journal: Life sciences 20010713
Title: Apoptosis induced in rats by 4-vinylcyclohexene diepoxide is associated with activation of the caspase cascades.
Journal: Biology of reproduction 20010701
Title: Stereochemical aspects in the 4-vinylcyclohexene biotransformation with rat liver microsomes and purified p450s. monoepoxides and diols.
Journal: Chemical research in toxicology 20010501
Title: Ovarian toxicity of 4-vinylcyclohexene diepoxide: a mechanistic model.
Journal: Toxicologic pathology 20010101
Title: Mechanisms of ovotoxicity induced by environmental chemicals: 4-vinylcyclohexene diepoxide as a model chemical.
Journal: Advances in experimental medicine and biology 20010101
Title: Induction of cytochrome P-450 enzymes after repeated exposure to 4-vinylcyclohexene in B6C3F1 mice.
Journal: Drug metabolism and disposition: the biological fate of chemicals 19990201
Title: Enhanced expression of bax in small preantral follicles during 4-vinylcyclohexene diepoxide-induced ovotoxicity in the rat.
Journal: Toxicology and applied pharmacology 19960801
Title: Irritant symptoms and immunologic responses to multiple chemicals: importance of clinical and immunologic correlations.
Journal: International archives of allergy and applied immunology 19880101